The University of Chicago Header Logo

Search Result Details

Back to Search Results
This page shows the details of why an item matched the keywords from your search.
Search Results
Nakamura, Yusuke
One or more keywords matched the following items that are connected to Nakamura, Yusuke
Item TypeName
Concept Alleles
Concept Amino Acid Sequence
Concept Analysis of Variance
Concept Base Sequence
Concept Genetic Vectors
Concept DNA Mutational Analysis
Concept Genes, Dominant
Concept Genetic Techniques
Concept Genetics
Concept Genes
Concept Genes, MHC Class II
Concept Oncogenes
Concept Genetic Engineering
Concept Genes, MHC Class I
Concept Multigene Family
Concept Genetics, Medical
Concept Genetics, Population
Concept Models, Molecular
Concept Models, Genetic
Concept Molecular Sequence Data
Concept Molecular Weight
Concept Recombination, Genetic
Concept Repetitive Sequences, Nucleic Acid
Concept Major Histocompatibility Complex
Concept Selection, Genetic
Concept Polymorphism, Genetic
Concept Pseudogenes
Concept Genetic Markers
Concept Regression Analysis
Concept Sequence Homology, Nucleic Acid
Concept Cluster Analysis
Concept Transcription, Genetic
Concept Genome
Concept Sequence Homology, Amino Acid
Concept Genetic Variation
Concept Transduction, Genetic
Concept Gene Library
Concept RNA Splice Sites
Concept Principal Component Analysis
Concept Genes, Tumor Suppressor
Concept Genome, Viral
Concept Molecular Conformation
Concept Leukemia, Myeloid, Acute
Concept Sequence Analysis, DNA
Concept Genes, APC
Concept Genes, Reporter
Concept Consensus Sequence
Concept Molecular Chaperones
Concept Genes, MDR
Concept src Homology Domains
Concept Genetic Association Studies
Concept Molecular Diagnostic Techniques
Concept Genetic Pleiotropy
Concept Exome
Concept Genetic Diseases, X-Linked
Concept Microarray Analysis
Concept Oligonucleotide Array Sequence Analysis
Concept Genes, BRCA1
Concept Genetic Diseases, Inborn
Concept Databases, Genetic
Concept Promoter Regions, Genetic
Concept Genetic Research
Concept Molecular Targeted Therapy
Concept Regulatory Elements, Transcriptional
Concept Multivariate Analysis
Concept Survival Analysis
Concept Open Reading Frames
Concept Meta-Analysis as Topic
Concept Genetic Therapy
Concept Molecular Structure
Concept Genome, Human
Concept Genes, p53
Concept Molecular Epidemiology
Concept Metabolic Networks and Pathways
Concept Genetic Heterogeneity
Concept Gene Components
Concept Transcriptome
Concept Mendelian Randomization Analysis
Concept Molecular Sequence Annotation
Concept Tissue Array Analysis
Concept Genes, Neoplasm
Concept Blood Chemical Analysis
Concept Cloning, Molecular
Concept Enhancer Elements, Genetic
Concept Genetic Testing
Concept Genetic Linkage
Concept Translocation, Genetic
Concept Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Concept Conserved Sequence
Concept Sequence Analysis, RNA
Concept Genetic Predisposition to Disease
Concept Polymorphism, Single Nucleotide
Concept Protein Array Analysis
Concept Quantitative Trait Loci
Concept Epigenesis, Genetic
Concept Genetic Loci
Concept Nucleotide Motifs
Academic Article The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Academic Article Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.
Academic Article An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines.
Academic Article A physical and genetic linkage map of the distal long arm of human chromosome 5.
Academic Article Expression profiles of non-small cell lung cancers on cDNA microarrays: identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs.
Academic Article Gene-expression profiles of human tumor xenografts in nude mice treated orally with the EGFR tyrosine kinase inhibitor ZD1839.
Academic Article Ring finger protein 43 as a new target for cancer immunotherapy.
Academic Article Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling.
Academic Article Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.
Academic Article Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
Academic Article Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
Academic Article A SNP in the ABCC11 gene is the determinant of human earwax type.
Academic Article Multiplex PCR-based real-time invader assay (mPCR-RETINA): a novel SNP-based method for detecting allelic asymmetries within copy number variation regions.
Academic Article Increased expression of insulin-like growth factor-II messenger RNA-binding protein 1 is associated with tumor progression in patients with lung cancer.
Academic Article When good drugs go bad.
Academic Article Genome-wide detection and characterization of positive selection in human populations.
Academic Article Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients.
Academic Article Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
Academic Article Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.
Academic Article Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function.
Academic Article Predicting response to docetaxel neoadjuvant chemotherapy for advanced breast cancers through genome-wide gene expression profiling.
Academic Article Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
Academic Article Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
Academic Article Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.
Academic Article Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.
Academic Article Japanese population structure, based on SNP genotypes from 7003 individuals compared to other ethnic groups: effects on population-based association studies.
Academic Article A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
Academic Article A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma.
Academic Article Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.
Academic Article Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
Academic Article Expression of novel molecules, MICAL2-PV (MICAL2 prostate cancer variants), increases with high Gleason score and prostate cancer progression.
Academic Article Automated SNPs typing system based on the Invader assay.
Academic Article Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
Academic Article Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.
Academic Article Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients.
Academic Article Common variations in PSMD3-CSF3 and PLCB4 are associated with neutrophil count.
Academic Article Genome-wide association study of intracranial aneurysm identifies three new risk loci.
Academic Article Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand.
Academic Article Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.
Academic Article Functional SNP of ARHGEF10 confers risk of atherothrombotic stroke.
Academic Article PADI4 polymorphism predisposes male smokers to rheumatoid arthritis.
Academic Article Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.
Academic Article A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.
Academic Article Establishment of a standardized system to perform population structure analyses with limited sample size or with different sets of SNP genotypes.
Academic Article Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
Academic Article Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
Academic Article A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.
Academic Article Common variation in GPC5 is associated with acquired nephrotic syndrome.
Academic Article Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility.
Academic Article Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population.
Academic Article A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
Academic Article SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
Academic Article Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.
Academic Article Should CYP2D6 inhibitors be administered in conjunction with tamoxifen?
Academic Article Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.
Academic Article Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese.
Academic Article A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.
Academic Article Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis.
Academic Article Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese.
Academic Article Genome-wide association meta-analysis identifies new endometriosis risk loci.
Academic Article Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
Academic Article A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
Academic Article Evaluating genetic risk for prostate cancer among Japanese and Latinos.
Academic Article Chondrolectin is a novel diagnostic biomarker and a therapeutic target for lung cancer.
Academic Article Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.
Academic Article A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
Academic Article A genome-wide association study identifies three new risk loci for Kawasaki disease.
Academic Article Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
Academic Article SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
Academic Article Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population.
Academic Article Multiple loci are associated with white blood cell phenotypes.
Academic Article Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.
Academic Article New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study.
Academic Article Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy.
Academic Article Physical localization of 70 polymorphic markers to human chromosome 5 by fluorescence in situ hybridization.
Academic Article Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response.
Academic Article A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
Academic Article A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression.
Academic Article Meta-analysis identifies common variants associated with body mass index in east Asians.
Academic Article A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis.
Academic Article A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
Academic Article Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.
Academic Article A genome-wide association study identifies genetic variants in the CDKN2BAS locus associated with endometriosis in Japanese.
Academic Article Optineurin mutations in Japanese amyotrophic lateral sclerosis.
Academic Article Replication analysis of SNPs on 9p21.2 and 19p13.3 with amyotrophic lateral sclerosis in East Asians.
Academic Article Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese.
Academic Article Pharmacogenomics of tamoxifen: roles of drug metabolizing enzymes and transporters.
Academic Article Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.
Academic Article PlatinumCNV: a Bayesian Gaussian mixture model for genotyping copy number polymorphisms using SNP array signal intensity data.
Academic Article A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.
Academic Article Prostate cancer genomics, biology, and risk assessment through genome-wide association studies.
Academic Article A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
Academic Article A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.
Academic Article Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
Academic Article Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes.
Academic Article A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.
Academic Article Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
Academic Article Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.
Academic Article Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.
Academic Article Identification of nine novel loci associated with white blood cell subtypes in a Japanese population.
Academic Article Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
Academic Article Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.
Academic Article IRX4 at 5p15 suppresses prostate cancer growth through the interaction with vitamin D receptor, conferring prostate cancer susceptibility.
Academic Article Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.
Academic Article Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.
Academic Article A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.
Academic Article Meta-analysis identifies six new susceptibility loci for atrial fibrillation.
Academic Article Pharmacogenomics and patient care: one size does not fit all.
Academic Article Functional variants in NFKBIE and RTKN2 involved in activation of the NF-?B pathway are associated with rheumatoid arthritis in Japanese.
Academic Article Physical and genetic map of 5q31: use of fluorescence in situ hybridization data to identify errors in the CEPH database. Centre d'Etude de Polymorphisme Humain.
Academic Article A second generation human haplotype map of over 3.1 million SNPs.
Academic Article Activation of KIF4A as a prognostic biomarker and therapeutic target for lung cancer.
Academic Article Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.
Academic Article SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
Academic Article CYP2D6 genotyping for functional-gene dosage analysis by allele copy number detection.
Academic Article Genome-wide association study of hematological and biochemical traits in a Japanese population.
Academic Article A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
Academic Article A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility.
Academic Article Replication study for the association between four Loci identified by a genome-wide association study on European American subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese subjects with type 2 diabetes.
Academic Article Genome-wide association study of pancreatic cancer in Japanese population.
Academic Article Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).
Academic Article Interstitial lung disease in gefitinib-treated Japanese patients with non-small-cell lung cancer: genome-wide analysis of genetic data.
Academic Article Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
Academic Article Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.
Academic Article ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations.
Academic Article Prediction of chemosensitivity for patients with acute myeloid leukemia, according to expression levels of 28 genes selected by genome-wide complementary DNA microarray analysis.
Academic Article Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
Academic Article Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy.
Academic Article Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population.
Academic Article Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
Academic Article Lack of association between variations of PDE4D and ischemic stroke in the Japanese population.
Academic Article A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
Academic Article Contribution of a haplotype in the HLA region to anti-cyclic citrullinated peptide antibody positivity in rheumatoid arthritis, independently of HLA-DRB1.
Academic Article Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population.
Academic Article Polymorphic human insulin-responsive glucose-transporter gene on chromosome 17p13.
Academic Article Development of new HLA-B*3505 genotyping method using Invader assay.
Academic Article Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.
Academic Article IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.
Academic Article Meta-analysis of published studies identified eight additional common susceptibility loci for Crohn's disease and ulcerative colitis.
Academic Article Genome-wide gene expression profiles of ovarian carcinoma: Identification of molecular targets for the treatment of ovarian carcinoma.
Academic Article A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
Academic Article HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.
Academic Article A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
Academic Article Identification of Epstein-Barr virus-induced gene 3 as a novel serum and tissue biomarker and a therapeutic target for lung cancer.
Academic Article Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
Academic Article A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.
Academic Article A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.
Academic Article Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese.
Academic Article Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene.
Academic Article Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.
Academic Article Association of allelic loss at 8p22 with poor prognosis among breast cancer cases treated with high-dose adjuvant chemotherapy.
Academic Article Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray.
Academic Article Correlation of allelic losses and clinicopathological factors in 504 primary breast cancers.
Academic Article Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy.
Academic Article Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21.
Academic Article Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.
Academic Article Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.
Academic Article Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors.
Academic Article Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations.
Academic Article Genome-wide gene expression profile analysis of esophageal squamous cell carcinomas.
Academic Article Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4.
Academic Article Similarity of the allele frequency and linkage disequilibrium pattern of single nucleotide polymorphisms in drug-related gene loci between Thai and northern East Asian populations: implications for tagging SNP selection in Thais.
Academic Article Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction.
Academic Article Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray.
Academic Article Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray.
Academic Article Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
Academic Article Genes associated with liver metastasis of colon cancer, identified by genome-wide cDNA microarray.
Academic Article Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma.
Academic Article Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction.
Academic Article Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes.
Academic Article Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.
Academic Article Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53.
Academic Article Functional haplotypes of IL-12B are associated with childhood atopic asthma.
Academic Article A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.
Academic Article Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors.
Academic Article Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
Academic Article Molecular features of hormone-refractory prostate cancer cells by genome-wide gene expression profiles.
Academic Article Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis.
Academic Article A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.
Academic Article Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.
Academic Article Association study of 71 European Crohn's disease susceptibility loci in a Japanese population.
Academic Article Regulation of protein Citrullination through p53/PADI4 network in DNA damage response.
Academic Article Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Academic Article An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
Academic Article Common variants in CASP3 confer susceptibility to Kawasaki disease.
Academic Article The textile plot: a new linkage disequilibrium display of multiple-single nucleotide polymorphism genotype data.
Academic Article Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
Academic Article Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs.
Academic Article Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.
Academic Article Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.
Academic Article Impact of four loci on serum tamsulosin hydrochloride concentration.
Academic Article Variations in the FTO gene are associated with severe obesity in the Japanese.
Academic Article C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
Academic Article INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.
Academic Article Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
Academic Article Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.
Academic Article Characterization of an Opa interacting protein 5 involved in lung and esophageal carcinogenesis.
Academic Article A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese.
Academic Article Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Academic Article Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Academic Article MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
Academic Article Impact of PSCA variation on gastric ulcer susceptibility.
Academic Article A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.
Academic Article Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
Academic Article Genome-wide gene expression profiles of clear cell renal cell carcinoma: identification of molecular targets for treatment of renal cell carcinoma.
Academic Article A genomewide linkage analysis of Kawasaki disease: evidence for linkage to chromosome 12.
Academic Article Genome wide association study of age at menarche in the Japanese population.
Academic Article Association of the RIP2 gene with childhood atopic asthma.
Academic Article Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
Academic Article ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
Academic Article MOCSphaser: a haplotype inference tool from a mixture of copy number variation and single nucleotide polymorphism data.
Academic Article Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome.
Academic Article Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays.
Academic Article Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.
Academic Article Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
Academic Article Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus.
Academic Article Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
Academic Article A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
Academic Article TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
Academic Article Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese.
Academic Article Identification of a functional variant in the MICA promoter which regulates MICA expression and increases HCV-related hepatocellular carcinoma risk.
Academic Article Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.
Academic Article High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
Academic Article Identification of CAG repeat-containing genes expressed in human brain as candidate genes for autosomal dominant spinocerebellar ataxias and other neurodegenerative diseases.
Academic Article Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.
Academic Article Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice.
Academic Article Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.
Academic Article Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection.
Academic Article Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes.
Academic Article A functional polymorphism in the 5' UTR of GDF5 is associated with susceptibility to osteoarthritis.
Academic Article Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.
Academic Article Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.
Academic Article Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population.
Academic Article Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
Academic Article The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
Academic Article Cancer peptide vaccine therapy developed from oncoantigens identified through genome-wide expression profile analysis for bladder cancer.
Academic Article Whole-genome-wide association study in the Bulgarian population reveals HHAT as schizophrenia susceptibility gene.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6).
Academic Article An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes.
Academic Article Seven new loci associated with age-related macular degeneration.
Academic Article Pathway analysis of genome-wide data improves warfarin dose prediction.
Academic Article Cyclin K as a direct transcriptional target of the p53 tumor suppressor.
Academic Article Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Academic Article Trans-ethnic meta-analysis of white blood cell phenotypes.
Academic Article Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
Academic Article Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway.
Academic Article Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
Academic Article Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease.
Academic Article An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis.
Academic Article Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma.
Academic Article p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.
Academic Article A replication study for three nephrolithiasis loci at 5q35.3, 7p14.3 and 13q14.1 in the Japanese population.
Academic Article Critical role of lysine 134 methylation on histone H2AX for ?-H2AX production and DNA repair.
Academic Article Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy.
Academic Article New gene functions in megakaryopoiesis and platelet formation.
Academic Article The Xq22 inversion breakpoint interrupted a novel Ras-like GTPase gene in a patient with Duchenne muscular dystrophy and profound mental retardation.
Academic Article Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Academic Article Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8.
Academic Article Maturational sequence of neuroblastoma revealed by molecular analysis on cDNA microarrays.
Academic Article Comparison of gene expression profiles between Opisthorchis viverrini and non-Opisthorchis viverrini associated human intrahepatic cholangiocarcinoma.
Academic Article CD40 ligand gene and Kawasaki disease.
Academic Article DKK1, a negative regulator of Wnt signaling, is a target of the beta-catenin/TCF pathway.
Academic Article Isolation and characterization of a novel human gene, VANGL1, as a therapeutic target for hepatocellular carcinoma.
Academic Article Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis.
Academic Article Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
Academic Article Identification of Myc-associated protein with JmjC domain as a novel therapeutic target oncogene for lung cancer.
Academic Article Catalog of 238 variations among six human genes encoding solute carriers ( hSLCs) in the Japanese population.
Academic Article Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
Academic Article Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease.
Academic Article Activation of CDCA1-KNTC2, members of centromere protein complex, involved in pulmonary carcinogenesis.
Academic Article Classification of sensitivity or resistance of cervical cancers to ionizing radiation according to expression profiles of 62 genes selected by cDNA microarray analysis.
Academic Article The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
Academic Article ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
Academic Article Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.
Academic Article Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer.
Academic Article Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.
Academic Article Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.
Academic Article DNA variations in human and medical genetics: 25 years of my experience.
Academic Article Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.
Academic Article Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas.
Academic Article Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis.
Academic Article 906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.
Academic Article Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma.
Academic Article Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839).
Academic Article Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers.
Academic Article A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction.
Academic Article Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines.
Academic Article Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR.
Academic Article Oncogenic role of NALP7 in testicular seminomas.
Academic Article Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.
Academic Article Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase.
Academic Article Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).
Academic Article p53RDL1 regulates p53-dependent apoptosis.
Academic Article Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy.
Academic Article Host molecular defense mechanisms against Chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma.
Academic Article Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells.
Academic Article A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese.
Academic Article Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
Academic Article Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Academic Article Genome-wide association study identified SNP on 15q24 associated with bladder cancer risk in Japanese population.
Academic Article Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis.
Academic Article [Possible role of genetic factors on reduced risk for gastric cancer among duodenal ulcer patients].
Academic Article Expression profiles of two types of human knee-joint cartilage.
Academic Article Microarray analysis of gene-expression profiles in diffuse large B-cell lymphoma: identification of genes related to disease progression.
Academic Article High-density SNP map of human ITR, a gene associated with vascular remodeling.
Academic Article Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
Academic Article Vaccination with multiple peptides derived from novel cancer-testis antigens can induce specific T-cell responses and clinical responses in advanced esophageal cancer.
Academic Article Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
Academic Article Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas.
Academic Article SNPs in BRAP associated with risk of myocardial infarction in Asian populations.
Academic Article Genetic variants associated with angiotensin-converting enzyme inhibitor-associated angioedema.
Academic Article Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism.
Academic Article Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma.
Academic Article Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population.
Academic Article Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface.
Academic Article Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cells.
Academic Article Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma.
Academic Article Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
Academic Article Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.
Academic Article Genome-wide cDNA microarray analysis of gene-expression profiles involved in ovarian endometriosis.
Academic Article Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.
Academic Article Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
Academic Article A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2.
Academic Article Catalog of 178 variations in the Japanese population among eight human genes encoding G protein-coupled receptors (GPCRs).
Academic Article Analysis of gene-expression profiles after gamma irradiation of normal human fibroblasts.
Academic Article Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.
Academic Article Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas.
Academic Article Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
Academic Article Phosphorylation and activation of cell division cycle associated 8 by aurora kinase B plays a significant role in human lung carcinogenesis.
Academic Article A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
Academic Article Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy.
Academic Article Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
Academic Article WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation.
Academic Article Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
Academic Article hCDC4b, a regulator of cyclin E, as a direct transcriptional target of p53.
Academic Article Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.
Academic Article A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis.
Academic Article Plasma low-molecular-weight proteome profiling identified neuropeptide-Y as a prostate cancer biomarker polypeptide.
Academic Article Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.
Academic Article ESE-3, an Ets family transcription factor, is up-regulated in cellular senescence.
Academic Article Association of EMCN with susceptibility to rheumatoid arthritis in a Japanese population.
Academic Article A functional polymorphism in IL-18 is associated with severity of bronchial asthma.
Academic Article Tumor budding is a significant indicator of a poor prognosis in lung squamous cell carcinoma patients.
Academic Article Prediction of response to imatinib by cDNA microarray analysis.
Academic Article A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells.
Academic Article Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
Academic Article Genome-wide association study of breast cancer in the Japanese population.
Academic Article Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
Academic Article Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.
Academic Article Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
Academic Article High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis.
Academic Article [S-1/CDDP combined neoadjuvant chemotherapy and surgical resection for advanced gastric cancer. Analysis of 12 patients with lymph node metastasis in Saitama Red Cross Hospital].
Academic Article Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma.
Academic Article Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
Academic Article Recombination rates of genes expressed in human tissues.
Academic Article Japanese single nucleotide polymorphism database for 267 possible drug-related genes.
Academic Article The oncogenic polycomb histone methyltransferase EZH2 methylates lysine 120 on histone H2B and competes ubiquitination.
Academic Article hzAnalyzer: detection, quantification, and visualization of contiguous homozygosity in high-density genotyping datasets.
Academic Article Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.
Academic Article Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
Academic Article Cystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathway.
Academic Article IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C.
Academic Article Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
Academic Article Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population.
Academic Article Identification of an HLA-A2-restricted epitope peptide derived from hypoxia-inducible protein 2 (HIG2).
Academic Article Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.
Academic Article Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.
Academic Article HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.
Academic Article [BioBank Japan project].
Academic Article The construction of risk prediction models using GWAS data and its application to a type 2 diabetes prospective cohort.
Academic Article Activation of an oncogenic TBC1D7 (TBC1 domain family, member 7) protein in pulmonary carcinogenesis.
Academic Article Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
Academic Article Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
Academic Article ANLN plays a critical role in human lung carcinogenesis through the activation of RHOA and by involvement in the phosphoinositide 3-kinase/AKT pathway.
Academic Article A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population.
Academic Article Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
Academic Article Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.
Academic Article Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses.
Academic Article Expression profiles of metastatic brain tumor from lung adenocarcinomas on cDNA microarray.
Academic Article The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Academic Article Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.
Academic Article Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese.
Academic Article A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.
Academic Article A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
Academic Article The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Academic Article Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.
Academic Article The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells.
Academic Article A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.
Academic Article A rare polymorphic variant of NBS1 reduces DNA repair activity and elevates chromosomal instability.
Academic Article A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells.
Academic Article Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma by hypermethylation.
Academic Article Population-genetic nature of copy number variations in the human genome.
Academic Article Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro.
Academic Article Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer.
Academic Article Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray.
Academic Article A functional polymorphism in MMP-9 is associated with childhood atopic asthma.
Academic Article A single nucleotide polymorphism in KCNQ1 is associated with susceptibility to diabetic nephropathy in japanese subjects with type 2 diabetes.
Academic Article Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population.
Academic Article A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
Academic Article Identification of semaphorin3B as a direct target of p53.
Academic Article Prediction of outcome of advanced cervical cancer to thermoradiotherapy according to expression profiles of 35 genes selected by cDNA microarray analysis.
Academic Article Identification of SPARC as a candidate target antigen for immunotherapy of various cancers.
Academic Article Serial analysis of gene expression in progressing and regressing mouse tumors implicates the involvement of RANTES and TARC in antitumor immune responses.
Academic Article Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.
Academic Article Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.
Academic Article A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.
Academic Article Identification of PDZK4, a novel human gene with PDZ domains, that is upregulated in synovial sarcomas.
Academic Article Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction.
Academic Article Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer.
Academic Article SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation.
Academic Article The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1).
Academic Article An algorithm for inferring complex haplotypes in a region of copy-number variation.
Academic Article Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
Academic Article Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers.
Academic Article New correction algorithms for multiple comparisons in case-control multilocus association studies based on haplotypes and diplotype configurations.
Academic Article Heterozygous TGFBR2 mutations in Marfan syndrome.
Academic Article SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
Academic Article Thirteen single-nucleotide polymorphisms (SNPs) in the alcohol dehydrogenase 4 (ADH4) gene locus.
Academic Article International network of cancer genome projects.
Academic Article Expression profile analysis of colon cancer cells in response to sulindac or aspirin.
Academic Article Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population.
Academic Article Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.
Academic Article Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis.
Academic Article Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
Academic Article A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers.
Academic Article Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas.
Academic Article An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.
Academic Article FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.
Academic Article Isolation of development and differentiation enhancing factor-like 1 (DDEFL1) as a drug target for hepatocellular carcinomas.
Academic Article Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
Academic Article Molecular target therapy for synovial sarcoma.
Academic Article Large-scale single-nucleotide polymorphism (SNP) and haplotype analyses, using dense SNP Maps, of 199 drug-related genes in 752 subjects: the analysis of the association between uncommon SNPs within haplotype blocks and the haplotypes constructed with haplotype-tagging SNPs.
Academic Article Catalog of 77 single-nucleotide polymorphisms (SNPs) in the carbohydrate sulfotransferase 1 (CHST1) and carbohydrate sulfotransferase 3 (CHST3) genes.
Academic Article A phase ?I study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study).
Academic Article Isolation of a novel gene, CABC1, encoding a mitochondrial protein that is highly homologous to yeast activity of bc1 complex.
Academic Article Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues.
Academic Article Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
Academic Article Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor.
Academic Article Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
Academic Article Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.
Academic Article Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
Academic Article DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1 in renal cell carcinomas.
Academic Article Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients.
Academic Article The NSD family of protein methyltransferases in human cancer.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Identification of COX17 as a therapeutic target for non-small cell lung cancer.
Academic Article PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.
Academic Article SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells.
Academic Article Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy.
Academic Article Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.
Academic Article Understanding the functional significance of ghrelin processing and degradation.
Academic Article Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.
Academic Article Germline PARP4 mutations in patients with primary thyroid and breast cancers.
Academic Article Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
Academic Article Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway.
Academic Article Isolation of p53-target genes and their functional analysis.
Academic Article Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens.
Academic Article Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
Academic Article Identification of HLA-A24-restricted novel T Cell epitope peptides derived from P-cadherin and kinesin family member 20A.
Academic Article From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma.
Academic Article Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation.
Academic Article Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapy.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Academic Article Deep-sequencing of the T-cell receptor repertoire in patients with haplo-cord and matched-donor transplants.
Academic Article Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
Academic Article Integrated pathway analysis of nasopharyngeal carcinoma implicates the axonemal dynein complex in the Malaysian cohort.
Academic Article Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.
Academic Article Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
Academic Article p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.
Academic Article The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.
Academic Article Pharmacogenomics and drug toxicity.
Academic Article Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
Academic Article Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy.
Academic Article Diagnostic evaluation of RNA sequencing for the detection of genetic abnormalities associated with Ph-like acute lymphoblastic leukemia (ALL).
Academic Article Characterization of a VNTR polymorphism in the coding region of the CEL gene.
Academic Article Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors.
Academic Article Quantitative T cell repertoire analysis by deep cDNA sequencing of T cell receptor a and ß chains using next-generation sequencing (NGS).
Academic Article Mutations in the gene encoding KIAA1199 protein, an inner-ear protein expressed in Deiters' cells and the fibrocytes, as the cause of nonsyndromic hearing loss.
Academic Article Accurate automated clustering of two-dimensional data for single-nucleotide polymorphism genotyping by a combination of clustering methods: evaluation by large-scale real data.
Academic Article WHSC1L1 drives cell cycle progression through transcriptional regulation of CDC6 and CDK2 in squamous cell carcinoma of the head and neck.
Academic Article Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymes.
Academic Article Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan.
Academic Article Expression of hypoxia-inducible protein 2 in renal cell carcinoma: A promising candidate for molecular targeting therapy.
Academic Article Cross-sectional analysis of BioBank Japan clinical data: A large cohort of 200,000 patients with 47 common diseases.
Academic Article Overview of BioBank Japan follow-up data in 32 diseases.
Academic Article Overview of the BioBank Japan Project: Study design and profile.
Academic Article Demographic and lifestyle factors and survival among patients with esophageal and gastric cancer: The Biobank Japan Project.
Academic Article Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Academic Article Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort.
Academic Article Combined hepatocellular/cholangiocellular carcinoma with sarcomatoid features: genetic analysis for histogenesis.
Academic Article Integrated analysis of somatic mutations and immune microenvironment in malignant pleural mesothelioma.
Academic Article SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway.
Academic Article The Transcriptional Landscape of p53 Signalling Pathway.
Academic Article Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
Academic Article Quantitative analysis and clonal characterization of T-cell receptor ß repertoires in patients with advanced non-small cell lung cancer treated with cancer vaccine.
Academic Article Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.
Academic Article Development of small molecular compounds targeting cancer stem cells.
Academic Article Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer.
Academic Article Integrated analysis of somatic mutations and immune microenvironment of multiple regions in breast cancers.
Academic Article WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia.
Academic Article The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation.
Academic Article miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.
Academic Article GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
Academic Article The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck.
Academic Article Molecular targeting of cell-permeable peptide inhibits pancreatic ductal adenocarcinoma cell proliferation.
Academic Article Breast cancer: The translation of big genomic data to cancer precision medicine.
Academic Article Genome-wide association study identifies gastric cancer susceptibility loci at 12q24.11-12 and 20q11.21.
Academic Article MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
Academic Article TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients.
Academic Article Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients.
Academic Article Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population.
Academic Article CMOS-based bio-image sensor spatially resolves neural activity-dependent proton dynamics in the living brain.
Academic Article Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.
Academic Article Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.
Academic Article Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
Academic Article Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?
Academic Article CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
Academic Article Clinicopathologic significance of protein lysine methyltransferases in cancer.
Academic Article Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer.
Academic Article Genome-wide association study of epilepsy in a Japanese population identified an associated region at chromosome 12q24.
Academic Article Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
Academic Article Diversity in immunogenomics: the value and the challenge.
Academic Article Immunogenomics in personalized cancer treatments.
Academic Article Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis.
Academic Article A cross-population atlas of genetic associations for 220 human phenotypes.
Concept Spatio-Temporal Analysis
Academic Article Treatment satisfaction with molidustat in CKD-related anemia in non-dialysis patients: a post-hoc analysis of two clinical trials.
Academic Article Immunological analysis of hybrid neoantigen peptide encompassing class I/II neoepitope-pulsed dendritic cell vaccine.
Search Criteria
  • Molecular
  • analysis
  • genetic
  • pathways
  • leading
  • myeloid leukemias