| Item Type | Name |
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Concept
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Insulin-Like Growth Factor I
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Concept
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Platelet-Derived Growth Factor
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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Macrophage Colony-Stimulating Factor
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Concept
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Transforming Growth Factor beta
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Concept
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Receptors, Fibroblast Growth Factor
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Concept
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Receptors, Tumor Necrosis Factor
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Concept
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E2F4 Transcription Factor
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Concept
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Eukaryotic Initiation Factor-4E
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Concept
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Receptors, Tumor Necrosis Factor, Type I
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Concept
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Octamer Transcription Factor-1
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Concept
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Interferon Regulatory Factor-3
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Concept
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Tumor Necrosis Factor Decoy Receptors
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Concept
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GATA6 Transcription Factor
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Concept
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E2F2 Transcription Factor
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Concept
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NF-E2-Related Factor 2
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Concept
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Hypoxia-Inducible Factor 1
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Concept
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Transforming Growth Factor alpha
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Concept
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Transcription Factor RelA
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Concept
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Granulocyte Colony-Stimulating Factor
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Concept
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Receptors, Tumor Necrosis Factor, Member 10c
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Concept
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Myeloid Differentiation Factor 88
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Concept
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ADP-Ribosylation Factor 1
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Concept
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Receptors, Tumor Necrosis Factor, Type II
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|
Concept
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E2F1 Transcription Factor
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Concept
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STAT1 Transcription Factor
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Concept
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Vascular Endothelial Growth Factor A
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Concept
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Transcription Factor DP1
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Concept
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Host Cell Factor C1
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Concept
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Epidermal Growth Factor
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Concept
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Fibroblast Growth Factor 2
|
|
Concept
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Receptors, Transforming Growth Factor beta
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Concept
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E2F5 Transcription Factor
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Concept
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Apoptotic Protease-Activating Factor 1
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Academic Article
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Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
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Academic Article
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p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.
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Academic Article
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Phase I dose-escalation study of tumor necrosis factor-alpha and concomitant radiation therapy.
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Academic Article
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Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature.
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Academic Article
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Differential retention of tumor- and differentiation-suppressor functions in cells derived from a human squamous cell carcinoma.
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Academic Article
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Growth factors alter the therapeutic ratio in radiotherapy.
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Academic Article
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Phase I study of concomitant chemoradiotherapy with paclitaxel, fluorouracil, and hydroxyurea with granulocyte colony-stimulating factor support for patients with poor-prognosis cancer of the head and neck.
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Academic Article
|
Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein.
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Academic Article
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Increased injection number enhances adenoviral genetic radiotherapy.
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Academic Article
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Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage.
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Academic Article
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Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase.
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Academic Article
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Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
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Academic Article
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Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
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Academic Article
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Radiation-inducible gene therapy.
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Academic Article
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Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
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Academic Article
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Molecular targeting of gene therapy and radiotherapy.
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Academic Article
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E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
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Academic Article
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Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3.
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Academic Article
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TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene.
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Academic Article
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Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.
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Academic Article
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Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma.
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Academic Article
|
Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors.
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Academic Article
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cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor.
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Academic Article
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Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model.
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Academic Article
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Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.
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Academic Article
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Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells.
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Academic Article
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Transcriptional control of viral gene therapy by cisplatin.
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Academic Article
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Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.
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Academic Article
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Control of gene therapy by MDR1 and EGR1 promoter sequences in transcriptional targeting by chemotherapy (Review).
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Academic Article
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STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
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Academic Article
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Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy.
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Academic Article
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Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology.
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Academic Article
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Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance.
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Academic Article
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Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.
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Academic Article
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Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay.
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Academic Article
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Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation.
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Academic Article
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Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
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Academic Article
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Ionizing radiation: a genetic switch for cancer therapy.
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Academic Article
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Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
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Academic Article
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Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB.
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Academic Article
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TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors.
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Academic Article
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A Phase I trial of TNFerade biologic in patients with soft tissue sarcoma in the extremities.
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Academic Article
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MUCing around with tumor suppression.
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Academic Article
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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.
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Academic Article
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Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers.
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Academic Article
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Vascular endothelial growth factor pathway.
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Academic Article
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STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.
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Academic Article
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Where it's at really matters: in situ in vivo vascular endothelial growth factor spatially correlates with electron paramagnetic resonance pO2 images in tumors of living mice.
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Academic Article
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Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
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Academic Article
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Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines.
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Academic Article
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Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
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Academic Article
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Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth.
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Academic Article
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SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine.
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Academic Article
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Intensified concomitant chemoradiotherapy with and without filgrastim for poor-prognosis head and neck cancer.
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Academic Article
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Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy.
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Academic Article
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Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-beta-dependent activation of antigen-specific CD8+ T cells.
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Academic Article
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Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner.
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Academic Article
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The role of paclitaxel in the treatment of head and neck cancer.
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Academic Article
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Clonal interactions in a human squamous cell carcinoma.
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Academic Article
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Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
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Academic Article
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Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response.
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Academic Article
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Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.
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Academic Article
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Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.
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Academic Article
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Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy.
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Academic Article
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Spatial and temporal control of gene therapy using ionizing radiation.
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Academic Article
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Ketoconazole attenuates radiation-induction of tumor necrosis factor.
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Academic Article
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Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
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Academic Article
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Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
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Academic Article
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Retraction. Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1.
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Academic Article
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Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1.
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Academic Article
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Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.
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Academic Article
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Radiation tolerance and the new biology: growth factor involvement in radiation injury to the lung.
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Academic Article
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Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer.
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Academic Article
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Tumor production of angiostatin is enhanced after exposure to TNF-alpha.
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Academic Article
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Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
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Academic Article
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Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.
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Academic Article
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Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.
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Academic Article
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Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
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Academic Article
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The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
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Academic Article
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Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
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Academic Article
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Genetic radiotherapy overcomes tumor resistance to cytotoxic agents.
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Academic Article
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Platelet-derived growth factor stimulates bone resorption by monocyte monolayers.
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Academic Article
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Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation.
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Academic Article
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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
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Academic Article
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Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.
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Academic Article
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CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.
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Academic Article
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Systemic delivery of the tumor necrosis factor gene to tumors by a novel dual DNA-nanocomplex in a nanoparticle system.
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Academic Article
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BCL3 expression promotes resistance to alkylating chemotherapy in gliomas.
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Academic Article
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Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis.
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Academic Article
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Non-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.
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Academic Article
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Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity.
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Academic Article
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The relationship between expression of PD-L1 and HIF-1a in glioma cells under hypoxia.
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Academic Article
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Epitranscriptional regulation of TGF-ß pseudoreceptor BAMBI by m6A/YTHDF2 drives extrinsic radioresistance.
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