"Cycloheximide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
| Descriptor ID |
D003513
|
| MeSH Number(s) |
D03.383.621.808.240
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cycloheximide".
Below are MeSH descriptors whose meaning is more specific than "Cycloheximide".
This graph shows the total number of publications written about "Cycloheximide" by people in this website by year, and whether "Cycloheximide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 2 | 3 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 6 | 6 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cycloheximide" by people in Profiles.
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Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress. Cell. 2015 Sep 10; 162(6):1286-98.
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Degradation of a connexin40 mutant linked to atrial fibrillation is accelerated. J Mol Cell Cardiol. 2014 Sep; 74:330-9.
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Loss of PINK1 attenuates HIF-1a induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia. J Neurosci. 2014 Feb 19; 34(8):3079-89.
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A connexin50 mutant, CX50fs, that causes cataracts is unstable, but is rescued by a proteasomal inhibitor. J Biol Chem. 2013 Jul 12; 288(28):20427-34.
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HSV carrying WT REST establishes latency but reactivates only if the synthesis of REST is suppressed. Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):E498-506.
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Translational control of inducible nitric oxide synthase by p38 MAPK in islet ß-cells. Mol Endocrinol. 2013 Feb; 27(2):336-49.
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The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes. Proc Natl Acad Sci U S A. 2009 Jul 21; 106(29):12139-44.
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Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines. Mol Cancer Res. 2008 Mar; 6(3):501-8.
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The intrinsic apoptotic pathway is required for lipopolysaccharide-induced lung endothelial cell death. J Immunol. 2007 Aug 01; 179(3):1834-41.
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The role of protein synthesis in striatal long-term depression. J Neurosci. 2006 Nov 15; 26(46):11811-20.