 Lymphotoxin-alpha
"Lymphotoxin-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.
| Descriptor ID |
D008233
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| MeSH Number(s) |
D12.644.276.374.480.438 D12.644.276.374.750.500 D12.644.276.972.500 D12.776.467.374.480.438 D12.776.467.374.750.500 D12.776.467.972.500 D23.529.374.480.438 D23.529.374.750.500 D23.529.972.500
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| Concept/Terms |
Lymphotoxin-alpha- Lymphotoxin-alpha
- Lymphotoxin alpha
- Lymphotoxin
- TNF Superfamily, Member 1
- Tumor Necrosis Factor Ligand Superfamily Member 1
- Tumor Necrosis Factor-beta
- Tumor Necrosis Factor beta
- alpha-Lymphotoxin
- alpha Lymphotoxin
- TNF-beta
Lymphotoxin-alpha3- Lymphotoxin-alpha3
- Lymphotoxin alpha3
- Soluble Lymphotoxin-alpha
- Lymphotoxin-alpha, Soluble
- Soluble Lymphotoxin alpha
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Below are MeSH descriptors whose meaning is more general than "Lymphotoxin-alpha".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin-alpha".
This graph shows the total number of publications written about "Lymphotoxin-alpha" by people in this website by year, and whether "Lymphotoxin-alpha" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 2 | 2 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 4 | 2 | 6 | | 2003 | 4 | 2 | 6 | | 2004 | 3 | 0 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lymphotoxin-alpha" by people in Profiles.
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Wroblewska JA, Zhang Y, Tang H, Guo X, Nagler C, Fu YX. Cutting Edge: Lymphotoxin Signaling Is Essential for Clearance of Salmonella from the Gut Lumen and Generation of Anti-Salmonella Protective Immunity. J Immunol. 2017 01 01; 198(1):55-60.
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Kim TJ, Upadhyay V, Kumar V, Lee KM, Fu YX. Innate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironment. J Exp Med. 2014 Jun 30; 211(7):1421-31.
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Upadhyay V, Fu YX. Lymphotoxin organizes contributions to host defense and metabolic illness from innate lymphoid cells. Cytokine Growth Factor Rev. 2014 Apr; 25(2):227-33.
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Upadhyay V, Fu YX. Linking the microbiota and metabolic disease with lymphotoxin. Int Immunol. 2013 Jul; 25(7):397-403.
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Upadhyay V, Fu YX. Lymphotoxin signalling in immune homeostasis and the control of microorganisms. Nat Rev Immunol. 2013 Apr; 13(4):270-9.
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Ubeda C, Pamer EG. Securing the border: lymphotoxin, IL-23 and IL-22 keep out the bad guys and 'fatten' the homeland. Nat Immunol. 2012 Oct; 13(10):940-1.
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Upadhyay V, Poroyko V, Kim TJ, Devkota S, Fu S, Liu D, Tumanov AV, Koroleva EP, Deng L, Nagler C, Chang EB, Tang H, Fu YX. Lymphotoxin regulates commensal responses to enable diet-induced obesity. Nat Immunol. 2012 Oct; 13(10):947-53.
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Kolokythas A, Karas M, Sarna T, Flick W, Miloro M. Does cytokine profiling of aspirate from jaw cysts and tumors have a role in diagnosis? J Oral Maxillofac Surg. 2012 May; 70(5):1070-80.
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Tumanov AV, Koroleva EP, Guo X, Wang Y, Kruglov A, Nedospasov S, Fu YX. Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge. Cell Host Microbe. 2011 Jul 21; 10(1):44-53.
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Blink SE, Fu YX. IgE regulates T helper cell differentiation through FcgammaRIII mediated dendritic cell cytokine modulation. Cell Immunol. 2010; 264(1):54-60.
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