 Necrosis
"Necrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. Distinguish it from APOPTOSIS which is a normal, regulated cellular process.
| Descriptor ID |
D009336
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| MeSH Number(s) |
C23.550.717 G04.299.139.638
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Necrosis".
Below are MeSH descriptors whose meaning is more specific than "Necrosis".
This graph shows the total number of publications written about "Necrosis" by people in this website by year, and whether "Necrosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 3 | 3 | | 1983 | 0 | 4 | 4 | | 1984 | 0 | 2 | 2 | | 1985 | 0 | 2 | 2 | | 1987 | 1 | 3 | 4 | | 1988 | 1 | 1 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1992 | 0 | 2 | 2 | | 1993 | 0 | 1 | 1 | | 1995 | 0 | 7 | 7 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 6 | 6 | | 1998 | 0 | 4 | 4 | | 1999 | 0 | 3 | 3 | | 2000 | 0 | 7 | 7 | | 2001 | 0 | 7 | 7 | | 2002 | 0 | 4 | 4 | | 2003 | 1 | 4 | 5 | | 2004 | 2 | 5 | 7 | | 2005 | 0 | 4 | 4 | | 2006 | 1 | 5 | 6 | | 2007 | 0 | 2 | 2 | | 2009 | 0 | 5 | 5 | | 2010 | 2 | 7 | 9 | | 2011 | 0 | 4 | 4 | | 2012 | 1 | 3 | 4 | | 2013 | 0 | 6 | 6 | | 2014 | 0 | 7 | 7 | | 2015 | 0 | 5 | 5 | | 2016 | 0 | 1 | 1 | | 2017 | 2 | 4 | 6 | | 2018 | 1 | 4 | 5 | | 2019 | 0 | 4 | 4 | | 2020 | 1 | 1 | 2 | | 2021 | 0 | 4 | 4 | | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Necrosis" by people in Profiles.
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Zhang L, Luo H, Ni HM, Liu S, Xing H, Zhang J, Sellin M, Breslin S J P, Wei W, Denning MF, Small W, Ding WX, Huang S, Zhang J. Ripk3 signaling regulates HSCs during stress and represses radiation-induced leukemia in mice. Stem Cell Reports. 2022 06 14; 17(6):1428-1441.
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Chapel DB, Sharma A, Lastra RR, Maccio L, Bragantini E, Zannoni GF, George S, Quade BJ, Parra-Herran C, Nucci MR. A novel morphology-based risk stratification model for stage I uterine leiomyosarcoma: an analysis of 203 cases. Mod Pathol. 2022 06; 35(6):794-807.
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Cifu AS, Stein SL. Yellow Sac Spider Bite. N Engl J Med. 2021 Nov 11; 385(20):1893.
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Schulte JJ, Chapel DB, Attanoos R, Brcic L, Burn J, Butnor KJ, Chang N, Chen H, Dacic S, De Perrot M, Fukuoka J, Galateau-Salle F, Godschachner T, Hiroshima K, Klebe S, Krausz T, Litzky L, Marchevsky AM, Mueller J, Nabeshima K, Nicholson AG, Pal P, Roden AC, Rorvig S, Santoni-Rugiu E, Tazelaar H, Tsao MS, Walts AE, Weynand B, Zaizen Y, Zhang YZ, Husain AN. Comparison of Nuclear Grade, Necrosis, and Histologic Subtype Between Biopsy and Resection in Pleural Malignant Mesothelioma: An International Multi-Institutional Analysis. Am J Clin Pathol. 2021 Nov 08; 156(6):989-999.
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Stassen PMC, de Jonge PJF, Bruno MJ, Koch AD, Trindade AJ, Benias PC, Sejpal DV, Siddiqui UD, Chapman CG, Villa E, Tharian B, Inamdar S, Hwang JH, Barakat MT, Andalib I, Gaidhane M, Sarkar A, Shahid H, Tyberg A, Binmoeller K, Watson RR, Nett A, Schlag C, Abdelhafez M, Friedrich-Rust M, Schlachterman A, Chiang AL, Loren D, Kowalski T, Kahaleh M. Safety and efficacy of a novel resection system for direct endoscopic necrosectomy of walled-off pancreas necrosis: a prospective, international, multicenter trial. Gastrointest Endosc. 2022 03; 95(3):471-479.
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Meleca JB, Ahmad U, Prendes BL, Lamarre E. The "bowtie" reconstruction flap: A unique solution to cervical esophageal discontinuity repair. Am J Otolaryngol. 2021 Mar-Apr; 42(2):102890.
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Khan N, Downey J, Sanz J, Kaufmann E, Blankenhaus B, Pacis A, Pernet E, Ahmed E, Cardoso S, Nijnik A, Mazer B, Sassetti C, Behr MA, Soares MP, Barreiro LB, Divangahi M. M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity. Cell. 2020 10 29; 183(3):752-770.e22.
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Samaratunga H, Delahunt B, Srigley JR, Berney DM, Cheng L, Evans A, Furusato B, Leite KRM, MacLennan GT, Martignoni G, Moch H, Pan CC, Paner G, Ro J, Thunders M, Tsuzuki T, Wheeler T, van der Kwast T, Varma M, Williamson SR, Yaxley JW, Egevad L. Granular necrosis: a distinctive form of cell death in malignant tumours. Pathology. 2020 Aug; 52(5):507-514.
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Deucher A, Wool GD. How I investigate bone marrow necrosis. Int J Lab Hematol. 2019 Oct; 41(5):585-592.
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Egaña-Gorroño L, Chinnasamy P, Casimiro I, Almonte VM, Parikh D, Oliveira-Paula GH, Jayakumar S, Law C, Riascos-Bernal DF, Sibinga NES. Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques. Atherosclerosis. 2019 10; 289:184-194.
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