"Tyrosine 3-Monooxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydroxy-L-phenylalanine, dihydrobiopterin, and water. EC 1.14.16.2.
| Descriptor ID |
D014446
|
| MeSH Number(s) |
D08.811.682.690.708.923 D12.776.556.579.374.925
|
| Concept/Terms |
Tyrosine 3-Monooxygenase- Tyrosine 3-Monooxygenase
- 3-Monooxygenase, Tyrosine
- Tyrosine 3 Monooxygenase
- Tyrosine Hydroxylase
- Hydroxylase, Tyrosine
|
Below are MeSH descriptors whose meaning is more general than "Tyrosine 3-Monooxygenase".
Below are MeSH descriptors whose meaning is more specific than "Tyrosine 3-Monooxygenase".
This graph shows the total number of publications written about "Tyrosine 3-Monooxygenase" by people in this website by year, and whether "Tyrosine 3-Monooxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 0 | 3 | 3 |
| 2005 | 1 | 2 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 2 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tyrosine 3-Monooxygenase" by people in Profiles.
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Histologic validation of locus coeruleus MRI contrast in post-mortem tissue. Neuroimage. 2015 Jun; 113:235-45.
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Excitatory synaptic function and plasticity is persistently altered in ventral tegmental area dopamine neurons after prenatal ethanol exposure. Neuropsychopharmacology. 2015 Mar; 40(4):893-905.
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Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo. J Neurochem. 2013 Oct; 127(2):187-98.
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Calcium entry and a-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons. J Neurosci. 2013 Jun 12; 33(24):10154-64.
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Differential regulation of tyrosine hydroxylase by continuous and intermittent hypoxia. Adv Exp Med Biol. 2012; 758:381-5.
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DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 2011 Oct; 10(5):807-23.
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Acid sensitivity and ultrastructure of the retrotrapezoid nucleus in Phox2b-EGFP transgenic mice. J Comp Neurol. 2009 Nov 01; 517(1):69-86.
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The human insulin gene is part of a large open chromatin domain specific for human islets. Proc Natl Acad Sci U S A. 2009 Oct 13; 106(41):17419-24.
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Pattern-specific sustained activation of tyrosine hydroxylase by intermittent hypoxia: role of reactive oxygen species-dependent downregulation of protein phosphatase 2A and upregulation of protein kinases. Antioxid Redox Signal. 2009 Aug; 11(8):1777-89.
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Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats. J Neurosci. 2009 May 06; 29(18):5806-19.