Myogenic Regulatory Factors
"Myogenic Regulatory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of muscle-specific transcription factors which bind to DNA in control regions and thus regulate myogenesis. All members of this family contain a conserved helix-loop-helix motif which is homologous to the myc family proteins. These factors are only found in skeletal muscle. Members include the myoD protein (MYOD PROTEIN); MYOGENIN; myf-5, and myf-6 (also called MRF4 or herculin).
| Descriptor ID |
D018006
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| MeSH Number(s) |
D12.776.210.500.570 D12.776.260.103.750 D12.776.930.125.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myogenic Regulatory Factors".
Below are MeSH descriptors whose meaning is more specific than "Myogenic Regulatory Factors".
This graph shows the total number of publications written about "Myogenic Regulatory Factors" by people in this website by year, and whether "Myogenic Regulatory Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myogenic Regulatory Factors" by people in Profiles.
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Developmentally regulated expression of MEF2C limits the response to BCR engagement in transitional B cells. Eur J Immunol. 2012 May; 42(5):1327-36.
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Investigating divergent mechanisms of mesoderm development in arthropods: the expression of Ph-twist and Ph-mef2 in Parhyale hawaiensis. J Exp Zool B Mol Dev Evol. 2008 Jan 15; 310(1):24-40.
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Dephosphorylation and caspase processing generate distinct nuclear pools of histone deacetylase 4. Mol Cell Biol. 2007 Oct; 27(19):6718-32.
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TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters. Biochem Biophys Res Commun. 2002 Jun 21; 294(4):791-7.
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Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer. J Immunol. 1998 Nov 01; 161(9):4795-802.