Ribonucleoprotein, U1 Small Nuclear
"Ribonucleoprotein, U1 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction.
|Ribonucleoprotein, U1 Small Nuclear
- Ribonucleoprotein, U1 Small Nuclear
- U1 Small Nuclear Ribonucleoproteins
- Ribonucleoproteins, Small, U1
- Small Nuclear Ribonucleoproteins, U1
- U1 snRNP
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Below are the most recent publications written about "Ribonucleoprotein, U1 Small Nuclear" by people in Profiles.
Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor. Mol Cell. 2001 Jan; 7(1):227-32.
Altered expression level of a systemic nuclear autoantigen determines the fate of immune response to self. J Immunol. 1999 Jun 01; 162(11):6482-91.