 Ryanodine Receptor Calcium Release Channel
"Ryanodine Receptor Calcium Release Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
| Descriptor ID |
D019837
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| MeSH Number(s) |
D12.776.157.530.400.150.800 D12.776.210.500.800 D12.776.543.550.425.150.800 D12.776.543.585.400.150.800
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| Concept/Terms |
Ryanodine Receptor Calcium Release Channel- Ryanodine Receptor Calcium Release Channel
- Ryanodine Receptor
- Receptor, Ryanodine
- Ca Release Channel-Ryanodine Receptor
- Ca Release Channel Ryanodine Receptor
- Calcium-Ryanodine Receptor Complex
- Calcium Ryanodine Receptor Complex
- Complex, Calcium-Ryanodine Receptor
- Receptor Complex, Calcium-Ryanodine
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Below are MeSH descriptors whose meaning is more general than "Ryanodine Receptor Calcium Release Channel".
Below are MeSH descriptors whose meaning is more specific than "Ryanodine Receptor Calcium Release Channel".
This graph shows the total number of publications written about "Ryanodine Receptor Calcium Release Channel" by people in this website by year, and whether "Ryanodine Receptor Calcium Release Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1998 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 2 | 0 | 2 | | 2007 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ryanodine Receptor Calcium Release Channel" by people in Profiles.
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Kohli U, Aziz Z, Beaser AD, Nayak HM. A large deletion in RYR2 exon 3 is associated with nadolol and flecainide refractory catecholaminergic polymorphic ventricular tachycardia. Pacing Clin Electrophysiol. 2019 08; 42(8):1146-1154.
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Bovo E, Mazurek SR, de Tombe PP, Zima AV. Increased Energy Demand during Adrenergic Receptor Stimulation Contributes to Ca(2+) Wave Generation. Biophys J. 2015 Oct 20; 109(8):1583-91.
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Bovo E, Mazurek SR, Fill M, Zima AV. Cytosolic Ca²? buffering determines the intra-SR Ca²? concentration at which cardiac Ca²? sparks terminate. Cell Calcium. 2015 Sep; 58(3):246-53.
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Mazurek SR, Bovo E, Zima AV. Regulation of sarcoplasmic reticulum Ca(2+) release by cytosolic glutathione in rabbit ventricular myocytes. Free Radic Biol Med. 2014 Mar; 68:159-67.
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Nagele P. Exome sequencing: one small step for malignant hyperthermia, one giant step for our specialty--why exome sequencing matters to all of us, not just the experts. Anesthesiology. 2013 Nov; 119(5):1006-8.
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Bovo E, Dvornikov AV, Mazurek SR, de Tombe PP, Zima AV. Mechanisms of Ca²+ handling in zebrafish ventricular myocytes. Pflugers Arch. 2013 Dec; 465(12):1775-84.
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Biancalana V, Beggs AH, Das S, Jungbluth H, Kress W, Nishino I, North K, Romero NB, Laporte J. Clinical utility gene card for: Centronuclear and myotubular myopathies. Eur J Hum Genet. 2012 Oct; 20(10).
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Bovo E, Mazurek SR, Blatter LA, Zima AV. Regulation of sarcoplasmic reticulum Ca²? leak by cytosolic Ca²? in rabbit ventricular myocytes. J Physiol. 2011 Dec 15; 589(Pt 24):6039-50.
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Ross J, Badner J, Garrido H, Sheppard B, Chavira DA, Grados M, Woo JM, Doo P, Umaña P, Fournier E, Murray SS, Mathews CA. Genomewide linkage analysis in Costa Rican families implicates chromosome 15q14 as a candidate region for OCD. Hum Genet. 2011 Dec; 130(6):795-805.
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Wasserstrom JA, Shiferaw Y, Chen W, Ramakrishna S, Patel H, Kelly JE, O'Toole MJ, Pappas A, Chirayil N, Bassi N, Akintilo L, Wu M, Arora R, Aistrup GL. Variability in timing of spontaneous calcium release in the intact rat heart is determined by the time course of sarcoplasmic reticulum calcium load. Circ Res. 2010 Oct 29; 107(9):1117-26.
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