CRADD Signaling Adaptor Protein
"CRADD Signaling Adaptor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A death domain receptor signaling adaptor protein that plays a role in signaling the activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds to and activates CASPASES such as CASPASE 2.
|CRADD Signaling Adaptor Protein
- CRADD Signaling Adaptor Protein
- RIP-Associated Protein With a Death Domain
- RIP Associated Protein With a Death Domain
- RAIDD Signaling Adaptor Protein
- Caspase and Rip Adaptor with Death Domain Protein
Below are MeSH descriptors whose meaning is more general than "CRADD Signaling Adaptor Protein".
Below are MeSH descriptors whose meaning is more specific than "CRADD Signaling Adaptor Protein".
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Below are the most recent publications written about "CRADD Signaling Adaptor Protein" by people in Profiles.
Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant. Am J Hum Genet. 2016 Nov 03; 99(5):1117-1129.