 Interleukin-1 Receptor-Associated Kinases
"Interleukin-1 Receptor-Associated Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.
| Descriptor ID |
D053592
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| MeSH Number(s) |
D08.811.913.696.620.682.700.526 D12.644.360.379 D12.776.476.384
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| Concept/Terms |
Interleukin-1 Receptor-Associated Kinases- Interleukin-1 Receptor-Associated Kinases
- Interleukin 1 Receptor Associated Kinases
- Kinases, Interleukin-1 Receptor-Associated
- Receptor-Associated Kinases, Interleukin-1
- IRAK Kinases
- Kinases, IRAK
- IL-1 Receptor-Associated Kinase
- IL 1 Receptor Associated Kinase
- Kinase, IL-1 Receptor-Associated
- Receptor-Associated Kinase, IL-1
- Interleukin-1 Receptor-Associated Kinase
- Interleukin 1 Receptor Associated Kinase
- Kinase, Interleukin-1 Receptor-Associated
- Receptor-Associated Kinase, Interleukin-1
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1 Receptor-Associated Kinases".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1 Receptor-Associated Kinases".
This graph shows the total number of publications written about "Interleukin-1 Receptor-Associated Kinases" by people in this website by year, and whether "Interleukin-1 Receptor-Associated Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2007 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-1 Receptor-Associated Kinases" by people in Profiles.
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Chen Y, Zeng Z, Shen X, Wu Z, Dong Y, Cheng JC. MicroRNA-146a-5p Negatively Regulates Pro-Inflammatory Cytokine Secretion and Cell Activation in Lipopolysaccharide Stimulated Human Hepatic Stellate Cells through Inhibition of Toll-Like Receptor 4 Signaling Pathways. Int J Mol Sci. 2016 Jul 07; 17(7).
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Wu Q, van Dyk LF, Jiang D, Dakhama A, Li L, White SR, Gross A, Chu HW. Interleukin-1 receptor-associated kinase M (IRAK-M) promotes human rhinovirus infection in lung epithelial cells via the autophagic pathway. Virology. 2013 Nov; 446(1-2):199-206.
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Béla SR, Dutra MS, Mui E, Montpetit A, Oliveira FS, Oliveira SC, Arantes RM, Antonelli LR, McLeod R, Gazzinelli RT. Impaired innate immunity in mice deficient in interleukin-1 receptor-associated kinase 4 leads to defective type 1 T cell responses, B cell expansion, and enhanced susceptibility to infection with Toxoplasma gondii. Infect Immun. 2012 Dec; 80(12):4298-308.
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Pino-Yanes M, Ma SF, Sun X, Tejera P, Corrales A, Blanco J, Pérez-Méndez L, Espinosa E, Muriel A, Blanch L, Garcia JG, Villar J, Flores C. Interleukin-1 receptor-associated kinase 3 gene associates with susceptibility to acute lung injury. Am J Respir Cell Mol Biol. 2011 Oct; 45(4):740-5.
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Jacob CO, Zhu J, Armstrong DL, Yan M, Han J, Zhou XJ, Thomas JA, Reiff A, Myones BL, Ojwang JO, Kaufman KM, Klein-Gitelman M, McCurdy D, Wagner-Weiner L, Silverman E, Ziegler J, Kelly JA, Merrill JT, Harley JB, Ramsey-Goldman R, Vila LM, Bae SC, Vyse TJ, Gilkeson GS, Gaffney PM, Moser KL, Langefeld CD, Zidovetzki R, Mohan C. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6256-61.
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Jacob CO, Reiff A, Armstrong DL, Myones BL, Silverman E, Klein-Gitelman M, McCurdy D, Wagner-Weiner L, Nocton JJ, Solomon A, Zidovetzki R. Identification of novel susceptibility genes in childhood-onset systemic lupus erythematosus using a uniquely designed candidate gene pathway platform. Arthritis Rheum. 2007 Dec; 56(12):4164-73.
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Heckscher ES, Fetter RD, Marek KW, Albin SD, Davis GW. NF-kappaB, IkappaB, and IRAK control glutamate receptor density at the Drosophila NMJ. Neuron. 2007 Sep 20; 55(6):859-73.
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Cuschieri J, Umanskiy K, Solomkin J. PKC-zeta is essential for endotoxin-induced macrophage activation. J Surg Res. 2004 Sep; 121(1):76-83.
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Li X, Tupper JC, Bannerman DD, Winn RK, Rhodes CJ, Harlan JM. Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells. Infect Immun. 2003 Aug; 71(8):4414-20.
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