"B7-2 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
| Descriptor ID |
D051940
|
| MeSH Number(s) |
D12.776.467.150.200 D12.776.543.095.200 D23.050.301.285.200 D23.529.168.200
|
| Concept/Terms |
B7-2 Antigen- B7-2 Antigen
- B7 2 Antigen
- B7-2 Costimulatory Molecule
- Costimulatory Molecule, B7-2
- B70 Costimulatory Molecule
- Costimulatory Molecule, B70
- Early T Cell Costimulatory Molecule 1
- CD86 Antigens
- Antigen, B7-2
- Antigen, B7 2
- Antigens, CD86
- CD86 Antigen
- Antigen, CD86
|
Below are MeSH descriptors whose meaning is more general than "B7-2 Antigen".
Below are MeSH descriptors whose meaning is more specific than "B7-2 Antigen".
This graph shows the total number of publications written about "B7-2 Antigen" by people in this website by year, and whether "B7-2 Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 4 | 4 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 2 | 3 |
| 2013 | 0 | 3 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
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Below are the most recent publications written about "B7-2 Antigen" by people in Profiles.
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Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells. Immunity. 2016 Apr 19; 44(4):847-59.
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Regulatory T and B lymphocytes in a spontaneous autoimmune polyneuropathy. Clin Exp Immunol. 2016 Apr; 184(1):50-61.
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High intensity focused ultrasound enhances anti-tumor immunity by inhibiting the negative regulatory effect of miR-134 on CD86 in a murine melanoma model. Oncotarget. 2015 Nov 10; 6(35):37626-37.
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Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4? T cells. Immunity. 2013 Sep 19; 39(3):560-72.
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The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation. Biomaterials. 2013 Nov; 34(34):8776-85.
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Transplantation: The promise of co-stimulatory blockade in transplantation. Nat Rev Nephrol. 2013 Apr; 9(4):189-90.
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Transgenic CCL2 expression in the central nervous system results in a dysregulated immune response and enhanced lethality after coronavirus infection. J Virol. 2013 Mar; 87(5):2376-89.
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Dexamethasone promotes tolerance in vivo by enriching CD11clo CD40lo tolerogenic macrophages. Eur J Immunol. 2013 Jan; 43(1):219-27.
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CD86 is expressed on murine hematopoietic stem cells and denotes lymphopoietic potential. Blood. 2012 May 24; 119(21):4889-97.
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Lactobacilli secreting a tumor antigen and IL15 activates neutrophils and dendritic cells and generates cytotoxic T lymphocytes against cancer cells. Cell Immunol. 2011; 271(1):89-96.