 ZAP-70 Protein-Tyrosine Kinase
"ZAP-70 Protein-Tyrosine Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein tyrosine kinase that is required for T-CELL development and T-CELL ANTIGEN RECEPTOR function.
| Descriptor ID |
D051746
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| MeSH Number(s) |
D08.811.913.696.620.682.725.900 D12.776.476.950
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| Concept/Terms |
ZAP-70 Protein-Tyrosine Kinase- ZAP-70 Protein-Tyrosine Kinase
- Protein-Tyrosine Kinase, ZAP-70
- ZAP 70 Protein Tyrosine Kinase
- Syk-Related Tyrosine Kinase
- Syk Related Tyrosine Kinase
- Tyrosine Kinase, Syk-Related
- ZAP-70 Protein
- ZAP 70 Protein
- zeta-Chain Associated Protein Kinase (ZAP-70)
- 70 kDa Zeta-Associated Protein
- 70 kDa Zeta Associated Protein
- ZAP-70 Kinase
- Kinase, ZAP-70
- ZAP 70 Kinase
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Below are MeSH descriptors whose meaning is more general than "ZAP-70 Protein-Tyrosine Kinase".
Below are MeSH descriptors whose meaning is more specific than "ZAP-70 Protein-Tyrosine Kinase".
This graph shows the total number of publications written about "ZAP-70 Protein-Tyrosine Kinase" by people in this website by year, and whether "ZAP-70 Protein-Tyrosine Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2015 | 0 | 2 | 2 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "ZAP-70 Protein-Tyrosine Kinase" by people in Profiles.
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Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor. Elife. 2016 10 04; 5.
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Strati P, Uhm JH, Kaufmann TJ, Nabhan C, Parikh SA, Hanson CA, Chaffee KG, Call TG, Shanafelt TD. Prevalence and characteristics of central nervous system involvement by chronic lymphocytic leukemia. Haematologica. 2016 Apr; 101(4):458-65.
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Lucas DM, Ruppert AS, Lozanski G, Dewald GW, Lozanski A, Claus R, Plass C, Flinn IW, Neuberg DS, Paietta EM, Bennett JM, Jelinek DF, Gribben JG, Hussein MA, Appelbaum FR, Larson RA, Moore DF, Tallman MS, Byrd JC, Grever MR. Cytogenetic prioritization with inclusion of molecular markers predicts outcome in previously untreated patients with chronic lymphocytic leukemia treated with fludarabine or fludarabine plus cyclophosphamide: a long-term follow-up study of the US intergroup phase III trial E2997. Leuk Lymphoma. 2015; 56(11):3031-7.
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Nakagawa R, Vukovic M, Tarafdar A, Cosimo E, Dunn K, McCaig AM, Holroyd A, McClanahan F, Ramsay AG, Gribben JG, Michie AM. Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCa subversion induces up-regulation of PKCßII expression in B lymphocytes. Haematologica. 2015 Apr; 100(4):499-510.
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Claus R, Lucas DM, Stilgenbauer S, Ruppert AS, Yu L, Zucknick M, Mertens D, Bühler A, Oakes CC, Larson RA, Kay NE, Jelinek DF, Kipps TJ, Rassenti LZ, Gribben JG, Döhner H, Heerema NA, Marcucci G, Plass C, Byrd JC. Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia. J Clin Oncol. 2012 Jul 10; 30(20):2483-91.
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Qiao G, Li Z, Minto AW, Shia J, Yang L, Bao L, Tschopp J, Gao JX, Wang J, Quigg RJ, Zhang J. Altered thymic selection by overexpressing cellular FLICE inhibitory protein in T cells causes lupus-like syndrome in a BALB/c but not C57BL/6 strain. Cell Death Differ. 2010 Mar; 17(3):522-33.
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Kujawski L, Ouillette P, Erba H, Saddler C, Jakubowiak A, Kaminski M, Shedden K, Malek SN. Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia. Blood. 2008 Sep 01; 112(5):1993-2003.
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Grever MR, Lucas DM, Dewald GW, Neuberg DS, Reed JC, Kitada S, Flinn IW, Tallman MS, Appelbaum FR, Larson RA, Paietta E, Jelinek DF, Gribben JG, Byrd JC. Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997. J Clin Oncol. 2007 Mar 01; 25(7):799-804.
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Meresse B, Curran SA, Ciszewski C, Orbelyan G, Setty M, Bhagat G, Lee L, Tretiakova M, Semrad C, Kistner E, Winchester RJ, Braud V, Lanier LL, Geraghty DE, Green PH, Guandalini S, Jabri B. Reprogramming of CTLs into natural killer-like cells in celiac disease. J Exp Med. 2006 May 15; 203(5):1343-55.
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Lee KH, Dinner AR, Tu C, Campi G, Raychaudhuri S, Varma R, Sims TN, Burack WR, Wu H, Wang J, Kanagawa O, Markiewicz M, Allen PM, Dustin ML, Chakraborty AK, Shaw AS. The immunological synapse balances T cell receptor signaling and degradation. Science. 2003 Nov 14; 302(5648):1218-22.
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