Zinc Finger E-box Binding Homeobox 2
"Zinc Finger E-box Binding Homeobox 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME.
| Descriptor ID |
D000074165
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| MeSH Number(s) |
D12.776.260.400.883 D12.776.260.703.700 D12.776.930.780.918
|
| Concept/Terms |
Zinc Finger E-box Binding Homeobox 2- Zinc Finger E-box Binding Homeobox 2
- Zinc Finger E box Binding Homeobox 2
- Zinc Finger E-box Binding Homeobox 2 Protein
- Zinc Finger E box Binding Homeobox 2 Protein
- Zeb2 Transcription Factor
- Transcription Factor, Zeb2
- Smad-Interacting Protein 1
- Smad Interacting Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Zinc Finger E-box Binding Homeobox 2".
Below are MeSH descriptors whose meaning is more specific than "Zinc Finger E-box Binding Homeobox 2".
This graph shows the total number of publications written about "Zinc Finger E-box Binding Homeobox 2" by people in this website by year, and whether "Zinc Finger E-box Binding Homeobox 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Zinc Finger E-box Binding Homeobox 2" by people in Profiles.
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Neuroimaging findings in Mowat-Wilson syndrome: a study of 54 patients. Genet Med. 2017 06; 19(6):691-700.
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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 2008 Apr 01; 22(7):894-907.