"Nanog Homeobox Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homeodomain protein and transcription regulator that functions in BLASTOCYST INNER CELL MASS and EMBRYONIC STEM CELL proliferation and CELL SELF RENEWAL. It confers pluripotency on embryonic stem cells and prevents their differentiation towards extraembryonic ENDODERM and trophectoderm (TROPHOBLAST) CELL LINEAGES.
| Descriptor ID |
D000071317
|
| MeSH Number(s) |
D12.776.260.400.530 D12.776.930.542
|
| Concept/Terms |
Nanog Homeobox Protein- Nanog Homeobox Protein
- Homeobox Protein, Nanog
- Nanog Protein
- Nanog Homeobox Transcription Factor
|
Below are MeSH descriptors whose meaning is more general than "Nanog Homeobox Protein".
Below are MeSH descriptors whose meaning is more specific than "Nanog Homeobox Protein".
This graph shows the total number of publications written about "Nanog Homeobox Protein" by people in this website by year, and whether "Nanog Homeobox Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nanog Homeobox Protein" by people in Profiles.
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Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase. Nat Commun. 2018 02 08; 9(1):578.
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Nutrient-driven O-linked N-acetylglucosamine (O-GlcNAc) cycling impacts neurodevelopmental timing and metabolism. J Biol Chem. 2017 04 14; 292(15):6076-6085.
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Cisplatin induces stemness in ovarian cancer. Oncotarget. 2016 May 24; 7(21):30511-22.
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Reporter Systems to Study Cancer Stem Cells. Methods Mol Biol. 2016; 1516:319-333.
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Aberrant lymphatic endothelial progenitors in lymphatic malformation development. PLoS One. 2015; 10(2):e0117352.
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The pluripotency factor Nanog is directly upregulated by the androgen receptor in prostate cancer cells. Prostate. 2014 Nov; 74(15):1530-43.
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Protecting against wayward human induced pluripotent stem cells with a suicide gene. Biomaterials. 2012 Apr; 33(11):3195-204.
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A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell. 2009 May 08; 4(5):403-15.