 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1990 | 0 | 4 | 4 | | 1991 | 2 | 3 | 5 | | 1992 | 1 | 3 | 4 | | 1993 | 6 | 1 | 7 | | 1994 | 4 | 4 | 8 | | 1995 | 7 | 7 | 14 | | 1996 | 2 | 6 | 8 | | 1997 | 8 | 2 | 10 | | 1998 | 1 | 5 | 6 | | 1999 | 8 | 4 | 12 | | 2000 | 3 | 6 | 9 | | 2001 | 3 | 8 | 11 | | 2002 | 3 | 14 | 17 | | 2003 | 4 | 15 | 19 | | 2004 | 6 | 14 | 20 | | 2005 | 7 | 23 | 30 | | 2006 | 2 | 17 | 19 | | 2007 | 6 | 8 | 14 | | 2008 | 11 | 7 | 18 | | 2009 | 6 | 19 | 25 | | 2010 | 8 | 14 | 22 | | 2011 | 9 | 15 | 24 | | 2012 | 8 | 13 | 21 | | 2013 | 4 | 16 | 20 | | 2014 | 2 | 15 | 17 | | 2015 | 3 | 26 | 29 | | 2016 | 8 | 17 | 25 | | 2017 | 9 | 19 | 28 | | 2018 | 6 | 19 | 25 | | 2019 | 7 | 10 | 17 | | 2020 | 2 | 3 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytokines" by people in Profiles.
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Daneshkhah A, Agrawal V, Eshein A, Subramanian H, Roy HK, Backman V. Evidence for possible association of vitamin D status with cytokine storm and unregulated inflammation in COVID-19 patients. Aging Clin Exp Res. 2020 Oct; 32(10):2141-2158.
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Abasiyanik MF, Wolfe K, Van Phan H, Lin J, Laxman B, White SR, Verhoef PA, Mutlu GM, Patel B, Tay S. Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes. Nat Commun. 2020 05 25; 11(1):2607.
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Wu J, Hayes BW, Phoenix C, Macias GS, Miao Y, Choi HW, Hughes FM, Todd Purves J, Lee Reinhardt R, Abraham SN. A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections. Nat Immunol. 2020 06; 21(6):671-683.
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James JA, Guthridge JM, Chen H, Lu R, Bourn RL, Bean K, Munroe ME, Smith M, Chakravarty E, Baer AN, Noaiseh G, Parke A, Boyle K, Keyes-Elstein L, Coca A, Utset T, Genovese MC, Pascual V, Utz PJ, Holers VM, Deane KD, Sivils KL, Aberle T, Wallace DJ, McNamara J, Franchimont N, St Clair EW. Unique Sjögren's syndrome patient subsets defined by molecular features. Rheumatology (Oxford). 2020 04 01; 59(4):860-868.
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Kong D, Wan Q, Li J, Zuo S, Liu G, Liu Q, Wang C, Bai P, Duan SZ, Zhou B, Gounari F, Lyu A, Lazarus M, Breyer RM, Yu Y. DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells. Circulation. 2020 02 25; 141(8):655-666.
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Molinero L, Li Y, Chang CW, Maund S, Berg M, Harrison J, Fassò M, O'Hear C, Hegde P, Emens LA. Tumor immune microenvironment and genomic evolution in a patient with metastatic triple negative breast cancer and a complete response to atezolizumab. J Immunother Cancer. 2019 10 23; 7(1):274.
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Goel G, Tye-Din JA, Qiao SW, Russell AK, Mayassi T, Ciszewski C, Sarna VK, Wang S, Goldstein KE, Dzuris JL, Williams LJ, Xavier RJ, Lundin KEA, Jabri B, Sollid LM, Anderson RP. Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease. Sci Adv. 2019 08; 5(8):eaaw7756.
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Bao Y, Sun YW, Ji J, Gan L, Zhang CF, Wang CZ, Yuan CS. Genkwanin ameliorates adjuvant-induced arthritis in rats through inhibiting JAK/STAT and NF-?B signaling pathways. Phytomedicine. 2019 Oct; 63:153036.
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Sharma A, Laxman B, Naureckas ET, Hogarth DK, Sperling AI, Solway J, Ober C, Gilbert JA, White SR. Associations between fungal and bacterial microbiota of airways and asthma endotypes. J Allergy Clin Immunol. 2019 11; 144(5):1214-1227.e7.
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Yang Y, Xu W, Peng D, Wang H, Zhang X, Wang H, Xiao F, Zhu Y, Ji Y, Gulukota K, Helseth DL, Mangold KA, Sullivan M, Kaul K, Wang E, Prabhakar BS, Li J, Wu X, Wang L, Seth P. An Oncolytic Adenovirus Targeting Transforming Growth Factor ß Inhibits Protumorigenic Signals and Produces Immune Activation: A Novel Approach to Enhance Anti-PD-1 and Anti-CTLA-4 Therapy. Hum Gene Ther. 2019 09; 30(9):1117-1132.
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