 Cytokines
"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
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| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1990 | 0 | 4 | 4 | | 1991 | 2 | 3 | 5 | | 1992 | 2 | 3 | 5 | | 1993 | 6 | 1 | 7 | | 1994 | 4 | 4 | 8 | | 1995 | 6 | 7 | 13 | | 1996 | 2 | 6 | 8 | | 1997 | 8 | 2 | 10 | | 1998 | 1 | 5 | 6 | | 1999 | 8 | 2 | 10 | | 2000 | 3 | 3 | 6 | | 2001 | 3 | 6 | 9 | | 2002 | 2 | 12 | 14 | | 2003 | 3 | 16 | 19 | | 2004 | 4 | 13 | 17 | | 2005 | 7 | 22 | 29 | | 2006 | 2 | 16 | 18 | | 2007 | 6 | 8 | 14 | | 2008 | 11 | 5 | 16 | | 2009 | 5 | 18 | 23 | | 2010 | 7 | 13 | 20 | | 2011 | 11 | 17 | 28 | | 2012 | 8 | 13 | 21 | | 2013 | 5 | 16 | 21 | | 2014 | 2 | 15 | 17 | | 2015 | 2 | 21 | 23 | | 2016 | 8 | 17 | 25 | | 2017 | 9 | 15 | 24 | | 2018 | 5 | 20 | 25 | | 2019 | 6 | 10 | 16 | | 2020 | 11 | 13 | 24 | | 2021 | 2 | 10 | 12 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytokines" by people in Profiles.
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Magnaye KM, Naughton KA, Huffman J, Hogarth DK, Naureckas ET, White SR, Ober C. A-to-I editing of miR-200b-3p in airway cells is associated with moderate-to-severe asthma. Eur Respir J. 2021 07; 58(1).
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Mansurov A, Lauterbach A, Budina E, Alpar AT, Hubbell JA, Ishihara J. Immunoengineering approaches for cytokine therapy. Am J Physiol Cell Physiol. 2021 08 01; 321(2):C369-C383.
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Liu CY, Cham CM, Chang EB. Epithelial wound healing in inflammatory bowel diseases: the next therapeutic frontier. Transl Res. 2021 10; 236:35-51.
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Kunz HE, Hart CR, Gries KJ, Parvizi M, Laurenti M, Dalla Man C, Moore N, Zhang X, Ryan Z, Polley EC, Jensen MD, Vella A, Lanza IR. Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity. Am J Physiol Endocrinol Metab. 2021 07 01; 321(1):E105-E121.
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Liu G, Lee JH, Parker ZM, Acharya D, Chiang JJ, van Gent M, Riedl W, Davis-Gardner ME, Wies E, Chiang C, Gack MU. ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity. Nat Microbiol. 2021 04; 6(4):467-478.
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Quandt J, Arnovitz S, Haghi L, Woehlk J, Mohsin A, Okoreeh M, Mathur PS, Emmanuel AO, Osman A, Krishnan M, Morin SB, Pearson AT, Sweis RF, Pekow J, Weber CR, Khazaie K, Gounari F. Wnt-ß-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression. Nat Immunol. 2021 04; 22(4):471-484.
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Major A, Collins J, Craney C, Heitman AK, Bauer E, Zerante E, Stock W, Bishop MR, Jasielec J. Management of hemophagocytic lymphohistiocytosis (HLH) associated with chimeric antigen receptor T-cell (CAR-T) therapy using anti-cytokine therapy: an illustrative case and review of the literature. Leuk Lymphoma. 2021 07; 62(7):1765-1769.
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Surette FA, Guthmiller JJ, Li L, Sturtz AJ, Vijay R, Pope RL, McClellan BL, Pack AD, Zander RA, Shao P, Lan LY, Fernandez-Ruiz D, Heath WR, Wilson PC, Butler NS. Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity. PLoS Pathog. 2021 02; 17(2):e1009288.
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Ferrara R, Campochiaro C, Garassino MC. Shifting From a "One Size Fits All" to a Tailored Approach for Immune-Related Adverse Events. J Thorac Oncol. 2021 02; 16(2):183-186.
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Kimani FW, Ajit J, Galluppi A, Manna S, Howitz WJ, Tang S, Esser-Kahn AP. Receptor-Ligand Kinetics Influence the Mechanism of Action of Covalently Linked TLR Ligands. ACS Chem Biol. 2021 02 19; 16(2):380-388.
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