"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Descriptor ID |
D016207
|
MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
|
Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 4 | 4 | 8 |
1995 | 6 | 7 | 13 |
1996 | 2 | 6 | 8 |
1997 | 8 | 2 | 10 |
1998 | 1 | 5 | 6 |
1999 | 8 | 4 | 12 |
2000 | 3 | 5 | 8 |
2001 | 4 | 8 | 12 |
2002 | 3 | 11 | 14 |
2003 | 5 | 16 | 21 |
2004 | 5 | 14 | 19 |
2005 | 7 | 22 | 29 |
2006 | 3 | 15 | 18 |
2007 | 6 | 9 | 15 |
2008 | 13 | 9 | 22 |
2009 | 7 | 20 | 27 |
2010 | 10 | 14 | 24 |
2011 | 10 | 17 | 27 |
2012 | 9 | 16 | 25 |
2013 | 5 | 20 | 25 |
2014 | 2 | 16 | 18 |
2015 | 3 | 25 | 28 |
2016 | 8 | 16 | 24 |
2017 | 8 | 22 | 30 |
2018 | 6 | 19 | 25 |
2019 | 8 | 15 | 23 |
2020 | 11 | 14 | 25 |
2021 | 5 | 17 | 22 |
2022 | 2 | 16 | 18 |
2023 | 0 | 13 | 13 |
2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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Discordant Effects of Polyamine Depletion by DENSpm and DFMO on ß-cell Cytokine Stress and Diabetes Outcomes in Mice. Endocrinology. 2024 Jan 16; 165(3).
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A pairwise cytokine code explains the organism-wide response to sepsis. Nat Immunol. 2024 Feb; 25(2):226-239.
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Base-editing mutagenesis maps alleles to tune human T cell functions. Nature. 2024 Jan; 625(7996):805-812.
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Deletion of Endogenous Neuregulin-4 Limits Adaptive Immunity During Interleukin-10 Receptor-Neutralizing Colitis. Inflamm Bowel Dis. 2023 11 02; 29(11):1778-1792.
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Vancomycin modestly attenuates symptom severity during onset of and recovery from exertional heat stroke in mice. J Appl Physiol (1985). 2023 12 01; 135(6):1348-1359.
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Identification of Clinically Significant Cytokine Signature Clusters in Patients With Septic Shock. Crit Care Med. 2023 12 01; 51(12):e253-e263.
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TGF-ß Signaling Prevents MHC Class II-Expressing Lymphatic Endothelial Cells from Reactivating Human Allogenic Memory CD4+ T Cells. J Immunol. 2023 09 01; 211(5):782-790.
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Hypoxia Potentiates the Inflammatory Fibroblast Phenotype Promoted by Pancreatic Cancer Cell-Derived Cytokines. Cancer Res. 2023 05 15; 83(10):1596-1610.
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Partial tumor irradiation plus pembrolizumab in treating large advanced solid tumor metastases. J Clin Invest. 2023 05 15; 133(10).
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Amino acid solution mitigates hypothermia response and intestinal damage following exertional heat stroke in male mice. Physiol Rep. 2023 05; 11(10):e15681.