 Caspase 9
"Caspase 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
| Descriptor ID |
D053453
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| MeSH Number(s) |
D08.811.277.656.262.500.126.550.900 D08.811.277.656.300.200.126.550.900 D12.644.360.075.405.550.900 D12.776.476.075.405.550.900
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| Concept/Terms |
Caspase 9- Caspase 9
- ICE-Like Apoptotic Protease 6
- ICE Like Apoptotic Protease 6
- Apoptotic Protease Activating Factor 3
- ICE-LAP6 Protein
- ICE LAP6 Protein
- Caspase-9
Procaspase-9- Procaspase-9
- Procaspase 9
- Pro-Caspase-9
- Pro Caspase 9
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Below are MeSH descriptors whose meaning is more general than "Caspase 9".
Below are MeSH descriptors whose meaning is more specific than "Caspase 9".
This graph shows the total number of publications written about "Caspase 9" by people in this website by year, and whether "Caspase 9" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 0 | 5 | 5 | | 2001 | 0 | 5 | 5 | | 2002 | 0 | 9 | 9 | | 2003 | 0 | 6 | 6 | | 2004 | 0 | 3 | 3 | | 2005 | 0 | 3 | 3 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 9" by people in Profiles.
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Wang CZ, Wan JY, Zhang CF, Lu F, Chen L, Yuan CS. Deglycosylation of wogonoside enhances its anticancer potential. J Cancer Res Ther. 2018 Sep; 14(Supplement):S594-S599.
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Saikia M, Jobava R, Parisien M, Putnam A, Krokowski D, Gao XH, Guan BJ, Yuan Y, Jankowsky E, Feng Z, Hu GF, Pusztai-Carey M, Gorla M, Sepuri NB, Pan T, Hatzoglou M. Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress. Mol Cell Biol. 2014 Jul; 34(13):2450-63.
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MohanKumar K, Killingsworth CR, McIlwain RB, Timpa JG, Jagadeeswaran R, Namachivayam K, Kurundkar AR, Kelly DR, Garzon SA, Maheshwari A. Intestinal epithelial apoptosis initiates gut mucosal injury during extracorporeal membrane oxygenation in the newborn piglet. Lab Invest. 2014 Feb; 94(2):150-60.
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Zhu H, Pytel P, Gomez CM. Selective inhibition of caspases in skeletal muscle reverses the apoptotic synaptic degeneration in slow-channel myasthenic syndrome. Hum Mol Genet. 2014 Jan 01; 23(1):69-77.
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Ko DC, Gamazon ER, Shukla KP, Pfuetzner RA, Whittington D, Holden TD, Brittnacher MJ, Fong C, Radey M, Ogohara C, Stark AL, Akey JM, Dolan ME, Wurfel MM, Miller SI. Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):E2343-52.
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Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa M, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson Å, Tönjes A, Dehghan A, Chouraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 2012; 8(3):e1002584.
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Du GJ, Wang CZ, Zhang ZY, Wen XD, Somogyi J, Calway T, He TC, Du W, Yuan CS. Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells. J Pharm Pharmacol. 2012 May; 64(5):727-34.
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Zhu H, Bhattacharyya BJ, Lin H, Gomez CM. Skeletal muscle IP3R1 receptors amplify physiological and pathological synaptic calcium signals. J Neurosci. 2011 Oct 26; 31(43):15269-83.
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Panduri V, Liu G, Surapureddi S, Kondapalli J, Soberanes S, de Souza-Pinto NC, Bohr VA, Budinger GR, Schumacker PT, Weitzman SA, Kamp DW. Role of mitochondrial hOGG1 and aconitase in oxidant-induced lung epithelial cell apoptosis. Free Radic Biol Med. 2009 Sep 15; 47(6):750-9.
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Yamauchi H, Katayama K, Ueno M, He XJ, Mikami T, Uetsuka K, Doi K, Nakayama H. Essential role of p53 in trophoblastic apoptosis induced in the developing rodent placenta by treatment with a DNA-damaging agent. Apoptosis. 2007 Oct; 12(10):1743-54.
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