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Richard A. Larson

TitleProfessor
InstitutionUniversity of Chicago
DepartmentMedicine-Hematology/Oncology
AddressChicago IL 60637
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    Collapse Biography 
    Collapse education and training
    University of Chicago, Chicago, ILFellowship1983Hematology & Oncology
    University of Chicago, Chicago. ILResidency1980Internal Medicine
    Stanford University School of Medicine, Stanford, CAMD1977Medicine
    King's College, University of Cambridge, Cambridge, England1973Chemistry
    Dartmouth College, Hanover, NHAB1972Chemistry

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. DeFilipp Z, Advani AS, Bachanova V, Cassaday RD, Deangelo DJ, Kebriaei P, Rowe JM, Seftel MD, Stock W, Tallman MS, Fanning S, Inamoto Y, Kansagra A, Johnston L, Nagler A, Sauter CS, Savani BN, Perales MA, Carpenter PA, Larson RA, Weisdorf D. Hematopoietic Cell Transplantation in the Treatment of Adult Acute Lymphoblastic Leukemia: Updated 2019 Evidence-Based Review from the American Society for Transplantation and Cellular Therapy. Biol Blood Marrow Transplant. 2019 Aug 22. PMID: 31446198.
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    2. Jabbour EJ, Gökbuget N, Kantarjian HM, Thomas X, Larson RA, Yoon SS, Ghobadi A, Topp MS, Tran Q, Franklin JL, Forman SJ, Stein AS. Transplantation in adults with relapsed/refractory acute lymphoblastic leukemia who are treated with blinatumomab from a phase 3 study. Cancer. 2019 Aug 21. PMID: 31433496.
      View in: PubMed
    3. Yin J, LaPlant B, Uy GL, Marcucci G, Blum W, Larson RA, Stone RM, Mandrekar SJ. Evaluation of event-free survival as a robust end point in untreated acute myeloid leukemia (Alliance A151614). Blood Adv. 2019 Jun 11; 3(11):1714-1721. PMID: 31171508.
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    4. Ustun C, Le-Rademacher J, Wang HL, Othus M, Sun Z, Major B, Zhang MJ, Storrick E, Lafky JM, Chow S, Mrózek K, Attar EC, Nand S, Bloomfield CD, Cripe LD, Tallman MS, Appelbaum F, Larson RA, Marcucci G, Roboz GJ, Uy GL, Stone RM, Jatoi A, Shea TC, de Lima M, Foran JM, Sandmaier BM, Litzow MR, Erba HP, Hurria A, Weisdorf DJ, Artz AS. Allogeneic hematopoietic cell transplantation compared to chemotherapy consolidation in older acute myeloid leukemia (AML) patients 60-75 years in first complete remission (CR1): an alliance (A151509), SWOG, ECOG-ACRIN, and CIBMTR study. Leukemia. 2019 May 09. PMID: 31073153.
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    5. Flynn KE, Mauro MJ, George G, Hinman A, Baim A, Kota V, Larson RA, Lipton JH, Thompson JE, Wadleigh M, Atallah E. Patients' perspectives on the definition of cure in chronic myeloid leukemia. Leuk Res. 2019 May; 80:40-42. PMID: 30955853.
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    6. Stock W, Luger SM, Advani AS, Yin J, Harvey RC, Mullighan CG, Willman CL, Fulton N, Laumann KM, Malnassy G, Paietta E, Parker E, Geyer S, Mrózek K, Bloomfield CD, Sanford B, Marcucci G, Liedtke M, Claxton DF, Foster MC, Bogart JA, Grecula JC, Appelbaum FR, Erba H, Litzow MR, Tallman MS, Stone RM, Larson RA. A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403. Blood. 2019 Apr 04; 133(14):1548-1559. PMID: 30658992.
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    7. Fan Y, Artz AS, van Besien K, Stock W, Larson RA, Odenike O, Godley LA, Kline J, Cunningham JM, LaBelle JL, Bishop MR, Liu H. Outcomes following second allogeneic stem cell transplant for disease relapse after T cell depleted transplant correlate with remission status and remission duration after the first transplant. Exp Hematol Oncol. 2019; 8:1. PMID: 30622841.
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    8. Hantel A, Larson RA. Imatinib is still recommended for frontline therapy for CML. Blood Adv. 2018 12 26; 2(24):3648-3652. PMID: 30587493.
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    9. Roboz GJ, Mandrekar SJ, Desai P, Laumann K, Walker AR, Wang ES, Kolitz JE, Powell BL, Attar EC, Stock W, Bloomfield CD, Kohlschmidt J, Mrózek K, Hassane DC, Garraway L, Jané-Valbuena J, Baltay M, Tracy A, Marcucci G, Stone RM, Larson RA. Randomized trial of 10 days of decitabine ± bortezomib in untreated older patients with AML: CALGB 11002 (Alliance). Blood Adv. 2018 12 26; 2(24):3608-3617. PMID: 30567725.
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    10. Woyach JA, Ruppert AS, Heerema NA, Zhao W, Booth AM, Ding W, Bartlett NL, Brander DM, Barr PM, Rogers KA, Parikh SA, Coutre S, Hurria A, Brown JR, Lozanski G, Blachly JS, Ozer HG, Major-Elechi B, Fruth B, Nattam S, Larson RA, Erba H, Litzow M, Owen C, Kuzma C, Abramson JS, Little RF, Smith SE, Stone RM, Mandrekar SJ, Byrd JC. Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL. N Engl J Med. 2018 12 27; 379(26):2517-2528. PMID: 30501481.
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    11. Kutny MA, Geyer S, Laumann KM, Gregory J, Willman CL, Stock W, Larson RA, Powell BL, Feusner JH. Outcome for pediatric acute promyelocytic leukemia patients at Children's Oncology Group sites on the Leukemia Intergroup Study CALGB 9710 (Alliance). Pediatr Blood Cancer. 2019 Mar; 66(3):e27542. PMID: 30393935.
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    12. Osman AEG, Anderson J, Churpek JE, Christ TN, Curran E, Godley LA, Liu H, Thirman MJ, Odenike T, Stock W, Larson RA. Treatment of Acute Promyelocytic Leukemia in Adults. J Oncol Pract. 2018 11; 14(11):649-657. PMID: 30423270.
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    13. D'Angelo CR, Novitsky B, Mee Lee S, Godley LA, Kline J, Larson RA, Liu H, Odenike O, Stock W, Bishop MR, Artz AS. Characterization of cancer comorbidity prior to allogeneic hematopoietic cell transplantation. Leuk Lymphoma. 2019 Mar; 60(3):629-638. PMID: 30070150.
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    14. Byrd JC, Ruppert AS, Heerema NA, Halvorson AE, Hoke E, Smith MR, Godwin JE, Couban S, Fehniger TA, Thirman MJ, Tallman MS, Appelbaum FR, Stone RM, Robinson S, Chang JE, Mandrekar SJ, Larson RA. Lenalidomide consolidation benefits patients with CLL receiving chemoimmunotherapy: results for CALGB 10404 (Alliance). Blood Adv. 2018 07 24; 2(14):1705-1718. PMID: 30030269.
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    15. Stein AS, Larson RA, Schuh AC, Stevenson W, Lech-Maranda E, Tran Q, Zimmerman Z, Kormany W, Topp MS. Exposure-adjusted adverse events comparing blinatumomab with chemotherapy in advanced acute lymphoblastic leukemia. Blood Adv. 2018 07 10; 2(13):1522-1531. PMID: 29954814.
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    16. Cheng JX, Chen L, Li Y, Cloe A, Yue M, Wei J, Watanabe KA, Shammo JM, Anastasi J, Shen QJ, Larson RA, He C, Le Beau MM, Vardiman JW. Author Correction: RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 06 06; 9(1):2286. PMID: 29875356.
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    17. Atallah E, Schiffer CA, Weinfurt KP, Zhang MJ, Radich JP, Oehler VG, Pinilla-Ibarz J, Deininger MWN, Lin L, Larson RA, Mauro MJ, Moore JO, Ritchie EK, Shah NP, Silver RT, Wadleigh M, Cortes J, Thompson J, Guhl J, Horowitz MM, Flynn KE. Design and rationale for the life after stopping tyrosine kinase inhibitors (LAST) study, a prospective, single-group longitudinal study in patients with chronic myeloid leukemia. BMC Cancer. 2018 04 02; 18(1):359. PMID: 29609532.
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    18. Cheng JX, Chen L, Li Y, Cloe A, Yue M, Wei J, Watanabe KA, Shammo JM, Anastasi J, Shen QJ, Larson RA, He C, Le Beau MM, Vardiman JW. RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 03 21; 9(1):1163. PMID: 29563491.
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    19. Stone RM, Manley PW, Larson RA, Capdeville R. Midostaurin: its odyssey from discovery to approval for treating acute myeloid leukemia and advanced systemic mastocytosis. Blood Adv. 2018 02 27; 2(4):444-453. PMID: 29487059.
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    20. Liu H, Zha Y, Choudhury N, Malnassy G, Fulton N, Green M, Park JH, Nakamura Y, Larson RA, Salazar AM, Odenike O, Gajewski TF, Stock W. WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia. Exp Hematol Oncol. 2018; 7:1. PMID: 29344432.
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    21. Wang AY, Weiner H, Green M, Chang H, Fulton N, Larson RA, Odenike O, Artz AS, Bishop MR, Godley LA, Thirman MJ, Kosuri S, Churpek JE, Curran E, Pettit K, Stock W, Liu H. A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia. J Hematol Oncol. 2018 01 05; 11(1):4. PMID: 29304833.
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    22. Tsai SB, Rhodes J, Liu H, Shore T, Bishop M, Cushing MM, Gergis U, Godley L, Kline J, Larson RA, Mayer S, Odenike O, Stock W, Wickrema A, van Besien K, Artz AS. Reduced-Intensity Allogeneic Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome Using Combined CD34-Selected Haploidentical Graft and a Single Umbilical Cord Unit Compared with Matched Unrelated Donor Stem Cells in Older Adults. Biol Blood Marrow Transplant. 2018 05; 24(5):997-1004. PMID: 29288821.
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    23. Stone RM, Larson RA, Döhner H. Midostaurin in FLT3-Mutated Acute Myeloid Leukemia. N Engl J Med. 2017 11 09; 377(19):1903. PMID: 29117486.
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    24. Stone RM, Mandrekar SJ, Sanford BL, Laumann K, Geyer S, Bloomfield CD, Thiede C, Prior TW, Döhner K, Marcucci G, Lo-Coco F, Klisovic RB, Wei A, Sierra J, Sanz MA, Brandwein JM, de Witte T, Niederwieser D, Appelbaum FR, Medeiros BC, Tallman MS, Krauter J, Schlenk RF, Ganser A, Serve H, Ehninger G, Amadori S, Larson RA, Döhner H. Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation. N Engl J Med. 2017 08 03; 377(5):454-464. PMID: 28644114.
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    25. Perl AE, Altman JK, Cortes J, Smith C, Litzow M, Baer MR, Claxton D, Erba HP, Gill S, Goldberg S, Jurcic JG, Larson RA, Liu C, Ritchie E, Schiller G, Spira AI, Strickland SA, Tibes R, Ustun C, Wang ES, Stuart R, Röllig C, Neubauer A, Martinelli G, Bahceci E, Levis M. Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1-2 study. Lancet Oncol. 2017 08; 18(8):1061-1075. PMID: 28645776.
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    26. Fenaux P, Muus P, Kantarjian H, Lyons RM, Larson RA, Sekeres MA, Becker PS, Orejudos A, Franklin J. Romiplostim monotherapy in thrombocytopenic patients with myelodysplastic syndromes: long-term safety and efficacy. Br J Haematol. 2017 09; 178(6):906-913. PMID: 28616874.
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    27. Larson RA. Managing CNS disease in adults with acute lymphoblastic leukemia. Leuk Lymphoma. 2018 01; 59(1):3-13. PMID: 28535095.
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    28. Hochhaus A, Larson RA, Guilhot F, Radich JP, Branford S, Hughes TP, Baccarani M, Deininger MW, Cervantes F, Fujihara S, Ortmann CE, Menssen HD, Kantarjian H, O'Brien SG, Druker BJ. Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia. N Engl J Med. 2017 03 09; 376(10):917-927. PMID: 28273028.
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    29. Knoebel RW, Larson RA. Pepsi® or Coke®? Influence of acid on dasatinib absorption. J Oncol Pharm Pract. 2018 Mar; 24(2):156-158. PMID: 29284366.
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    30. Khan N, Hantel A, Knoebel RW, Artz A, Larson RA, Godley LA, Thirman MJ, Liu H, Churpek JE, King D, Odenike O, Stock W. Efficacy of single-agent decitabine in relapsed and refractory acute myeloid leukemia. Leuk Lymphoma. 2017 09; 58(9):1-7. PMID: 28278716.
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    31. Uy GL, Mandrekar SJ, Laumann K, Marcucci G, Zhao W, Levis MJ, Klepin HD, Baer MR, Powell BL, Westervelt P, DeAngelo DJ, Stock W, Sanford B, Blum WG, Bloomfield CD, Stone RM, Larson RA. A phase 2 study incorporating sorafenib into the chemotherapy for older adults with FLT3-mutated acute myeloid leukemia: CALGB 11001. Blood Adv. 2017 Jan 24; 1(5):331-340. PMID: 29034366.
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    32. Mantha S, Goldman DA, Devlin SM, Lee JW, Zannino D, Collins M, Douer D, Iland HJ, Litzow MR, Stein EM, Appelbaum FR, Larson RA, Stone R, Powell BL, Geyer S, Laumann K, Rowe JM, Erba H, Coutre S, Othus M, Park JH, Wiernik PH, Tallman MS. Determinants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA era. Blood. 2017 Mar 30; 129(13):1763-1767. PMID: 28082441.
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    33. Li Z, Weng H, Su R, Weng X, Zuo Z, Li C, Huang H, Nachtergaele S, Dong L, Hu C, Qin X, Tang L, Wang Y, Hong GM, Huang H, Wang X, Chen P, Gurbuxani S, Arnovitz S, Li Y, Li S, Strong J, Neilly MB, Larson RA, Jiang X, Zhang P, Jin J, He C, Chen J. FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. Cancer Cell. 2017 01 09; 31(1):127-141. PMID: 28017614.
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    34. Wolfe AR, Trenton NJ, Debeb BG, Larson R, Ruffell B, Chu K, Hittelman W, Diehl M, Reuben JM, Ueno NT, Woodward WA. Mesenchymal stem cells and macrophages interact through IL-6 to promote inflammatory breast cancer in pre-clinical models. Oncotarget. 2016 Dec 13; 7(50):82482-82492. PMID: 27756885.
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    35. Cortes J, Talpaz M, Smith HP, Snyder DS, Khoury J, Bhalla KN, Pinilla-Ibarz J, Larson R, Mitchell D, Wise SC, Rutkoski TJ, Smith BD, Flynn DL, Kantarjian HM, Rosen O, Van Etten RA. Phase 1 dose-finding study of rebastinib (DCC-2036) in patients with relapsed chronic myeloid leukemia and acute myeloid leukemia. Haematologica. 2017 03; 102(3):519-528. PMID: 27927766.
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    36. Döhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, Büchner T, Dombret H, Ebert BL, Fenaux P, Larson RA, Levine RL, Lo-Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, Sanz M, Sierra J, Tallman MS, Tien HF, Wei AH, Löwenberg B, Bloomfield CD. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel. Blood. 2017 01 26; 129(4):424-447. PMID: 27895058.
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    37. Stock W, Diouf B, Crews KR, Pei D, Cheng C, Laumann K, Mandrekar SJ, Luger S, Advani A, Stone RM, Larson RA, Evans WE. An Inherited Genetic Variant in CEP72 Promoter Predisposes to Vincristine-Induced Peripheral Neuropathy in Adults With Acute Lymphoblastic Leukemia. Clin Pharmacol Ther. 2017 03; 101(3):391-395. PMID: 27618250.
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    38. Madan V, Shyamsunder P, Han L, Mayakonda A, Nagata Y, Sundaresan J, Kanojia D, Yoshida K, Ganesan S, Hattori N, Fulton N, Tan KT, Alpermann T, Kuo MC, Rostami S, Matthews J, Sanada M, Liu LZ, Shiraishi Y, Miyano S, Chendamarai E, Hou HA, Malnassy G, Ma T, Garg M, Ding LW, Sun QY, Chien W, Ikezoe T, Lill M, Biondi A, Larson RA, Powell BL, Lübbert M, Chng WJ, Tien HF, Heuser M, Ganser A, Koren-Michowitz M, Kornblau SM, Kantarjian HM, Nowak D, Hofmann WK, Yang H, Stock W, Ghavamzadeh A, Alimoghaddam K, Haferlach T, Ogawa S, Shih LY, Mathews V, Koeffler HP. Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia. Leukemia. 2016 12; 30(12):2430. PMID: 27713533.
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    39. Baljevic M, Dumitriu B, Lee JW, Paietta EM, Wiernik PH, Racevskis J, Chen C, Stein EM, Gallagher RE, Rowe JM, Appelbaum FR, Powell BL, Larson RA, Coutré SE, Lancet J, Litzow MR, Luger SM, Young NS, Tallman MS. Telomere Length Recovery: A Strong Predictor of Overall Survival in Acute Promyelocytic Leukemia. Acta Haematol. 2016; 136(4):210-218. PMID: 27632567.
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    40. Mullane KM, Nuss C, Ridgeway J, Prichard MN, Hartline CB, Theusch J, Mommeja-Marin H, Larson RA. Brincidofovir treatment of acyclovir-resistant disseminated varicella zoster virus infection in an immunocompromised host. Transpl Infect Dis. 2016 Oct; 18(5):785-790. PMID: 27481400.
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    41. Blum W, Sanford BL, Klisovic R, DeAngelo DJ, Uy G, Powell BL, Stock W, Baer MR, Kolitz JE, Wang ES, Hoke E, Mrózek K, Kohlschmidt J, Bloomfield CD, Geyer S, Marcucci G, Stone RM, Larson RA. Maintenance therapy with decitabine in younger adults with acute myeloid leukemia in first remission: a phase 2 Cancer and Leukemia Group B Study (CALGB 10503). Leukemia. 2017 01; 31(1):34-39. PMID: 27624549.
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    42. Rojek K, Nickels E, Neistadt B, Marquez R, Wickrema A, Artz A, van Besien K, Larson RA, Lee MK, Segal JP, King MC, Walsh T, Shimamura A, Keel SB, Churpek JE, Godley LA. Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy. Biol Blood Marrow Transplant. 2016 11; 22(11):2100-2103. PMID: 27497531.
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    43. Jiang X, Bugno J, Hu C, Yang Y, Herold T, Qi J, Chen P, Gurbuxani S, Arnovitz S, Strong J, Ferchen K, Ulrich B, Weng H, Wang Y, Huang H, Li S, Neilly MB, Larson RA, Le Beau MM, Bohlander SK, Jin J, Li Z, Bradner JE, Hong S, Chen J. Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles. Cancer Res. 2016 08 01; 76(15):4470-80. PMID: 27280396.
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    44. Debeb BG, Lacerda L, Larson R, Wolfe AR, Krishnamurthy S, Reuben JM, Ueno NT, Gilcrease M, Woodward WA. Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism. Oncotarget. 2016 May 10; 7(19):28329-39. PMID: 27078845.
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    45. Kantarjian HM, Stein AS, Bargou RC, Grande Garcia C, Larson RA, Stelljes M, Gökbuget N, Zugmaier G, Benjamin JE, Zhang A, Jia C, Topp MS. Blinatumomab treatment of older adults with relapsed/refractory B-precursor acute lymphoblastic leukemia: Results from 2 phase 2 studies. Cancer. 2016 07 15; 122(14):2178-85. PMID: 27143254.
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    46. Jiang X, Hu C, Arnovitz S, Bugno J, Yu M, Zuo Z, Chen P, Huang H, Ulrich B, Gurbuxani S, Weng H, Strong J, Wang Y, Li Y, Salat J, Li S, Elkahloun AG, Yang Y, Neilly MB, Larson RA, Le Beau MM, Herold T, Bohlander SK, Liu PP, Zhang J, Li Z, He C, Jin J, Hong S, Chen J. miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia. Nat Commun. 2016 04 26; 7:11452. PMID: 27116251.
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    47. Madan V, Shyamsunder P, Han L, Mayakonda A, Nagata Y, Sundaresan J, Kanojia D, Yoshida K, Ganesan S, Hattori N, Fulton N, Tan KT, Alpermann T, Kuo MC, Rostami S, Matthews J, Sanada M, Liu LZ, Shiraishi Y, Miyano S, Chendamarai E, Hou HA, Malnassy G, Ma T, Garg M, Ding LW, Sun QY, Chien W, Ikezoe T, Lill M, Biondi A, Larson RA, Powell BL, Lübbert M, Chng WJ, Tien HF, Heuser M, Ganser A, Koren-Michowitz M, Kornblau SM, Kantarjian HM, Nowak D, Hofmann WK, Yang H, Stock W, Ghavamzadeh A, Alimoghaddam K, Haferlach T, Ogawa S, Shih LY, Mathews V, Koeffler HP. Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia. Leukemia. 2016 08; 30(8):1672-81. PMID: 27063598.
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    48. Alachkar H, Fulton N, Sanford B, Malnassy G, Mutonga M, Larson RA, Bloomfield CD, Marcucci G, Nakamura Y, Stock W. Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia. Pharmacogenomics J. 2017 06; 17(3):274-279. PMID: 27019981.
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    49. Padula WV, Larson RA, Dusetzina SB, Apperley JF, Hehlmann R, Baccarani M, Eigendorff E, Guilhot J, Guilhot F, Hehlmann R, Mahon FX, Martinelli G, Mayer J, Müller MC, Niederwieser D, Saussele S, Schiffer CA, Silver RT, Simonsson B, Conti RM. Cost-effectiveness of Tyrosine Kinase Inhibitor Treatment Strategies for Chronic Myeloid Leukemia in Chronic Phase After Generic Entry of Imatinib in the United States. J Natl Cancer Inst. 2016 Jul; 108(7). PMID: 26944912.
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    50. Tsai SB, Liu H, Shore T, Fan Y, Bishop M, Cushing MM, Gergis U, Godley L, Kline J, Larson RA, Martinez G, Mayer S, Odenike O, Stock W, Wickrema A, van Besien K, Artz AS. Frequency and Risk Factors Associated with Cord Graft Failure after Transplant with Single-Unit Umbilical Cord Cells Supplemented by Haploidentical Cells with Reduced-Intensity Conditioning. Biol Blood Marrow Transplant. 2016 06; 22(6):1065-1072. PMID: 26912055.
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    51. DeBoer R, Koval G, Mulkey F, Wetzler M, Devine S, Marcucci G, Stone RM, Larson RA, Bloomfield CD, Geyer S, Mullighan CG, Stock W. Clinical impact of ABL1 kinase domain mutations and IKZF1 deletion in adults under age 60 with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB (Alliance) 10001 and 9665. Leuk Lymphoma. 2016 10; 57(10):2298-306. PMID: 26892479.
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    52. van Besien K, Hari P, Zhang MJ, Liu HT, Stock W, Godley L, Odenike O, Larson R, Bishop M, Wickrema A, Gergis U, Mayer S, Shore T, Tsai S, Rhodes J, Cushing MM, Korman S, Artz A. Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and graft-versus-host disease-free, relapse-free survival. Haematologica. 2016 05; 101(5):634-43. PMID: 26869630.
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    53. Hochhaus A, Saglio G, Hughes TP, Larson RA, Kim DW, Issaragrisil S, le Coutre PD, Etienne G, Dorlhiac-Llacer PE, Clark RE, Flinn IW, Nakamae H, Donohue B, Deng W, Dalal D, Menssen HD, Kantarjian HM. Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial. Leukemia. 2016 05; 30(5):1044-54. PMID: 26837842.
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    54. D'Angelo CR, Kocherginsky M, Pisano J, Bishop MR, Godley LA, Kline J, Larson RA, Liu H, Odenike O, Stock W, Artz AS. Incidence and predictors of respiratory viral infections by multiplex PCR in allogeneic hematopoietic cell transplant recipients 50 years and older including geriatric assessment. Leuk Lymphoma. 2016 08; 57(8):1807-13. PMID: 26699199.
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    55. Churpek JE, Marquez R, Neistadt B, Claussen K, Lee MK, Churpek MM, Huo D, Weiner H, Bannerjee M, Godley LA, Le Beau MM, Pritchard CC, Walsh T, King MC, Olopade OI, Larson RA. Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia. Cancer. 2016 Jan 15; 122(2):304-11. PMID: 26641009.
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    56. Castillo JJ, Mulkey F, Geyer S, Kolitz JE, Blum W, Powell BL, George SL, Larson RA, Stone RM. Relationship between obesity and clinical outcome in adults with acute myeloid leukemia: A pooled analysis from four CALGB (alliance) clinical trials. Am J Hematol. 2016 Feb; 91(2):199-204. PMID: 26526191.
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    57. Larson RA. Is there a best TKI for chronic phase CML? Blood. 2015 Nov 19; 126(21):2370-5. PMID: 26585806.
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    58. Devine SM, Owzar K, Blum W, Mulkey F, Stone RM, Hsu JW, Champlin RE, Chen YB, Vij R, Slack J, Soiffer RJ, Larson RA, Shea TC, Hars V, Sibley AB, Giralt S, Carter S, Horowitz MM, Linker C, Alyea EP. Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncology)/Blood and Marrow Transplant Clinical Trial Network 0502. J Clin Oncol. 2015 Dec 10; 33(35):4167-75. PMID: 26527780.
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    59. Li Z, Chen P, Su R, Li Y, Hu C, Wang Y, Arnovitz S, He M, Gurbuxani S, Zuo Z, Elkahloun AG, Li S, Weng H, Huang H, Neilly MB, Wang S, Olson EN, Larson RA, Le Beau MM, Zhang J, Jiang X, Wei M, Jin J, Liu PP, Chen J. Overexpression and knockout of miR-126 both promote leukemogenesis. Blood. 2015 Oct 22; 126(17):2005-15. PMID: 26361793.
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    338. Zhang Y, Strissel P, Strick R, Chen J, Nucifora G, Le Beau MM, Larson RA, Rowley JD. Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia. Proc Natl Acad Sci U S A. 2002 Mar 05; 99(5):3070-5. PMID: 11867721.
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    339. Diehl CA, Jafvert CT, Marley KA, Larson RA. Surfactant-assisted UV-photolysis of nitroarenes. Chemosphere. 2002 Jan; 46(4):553-60. PMID: 11838434.
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    342. Sievers EL, Larson RA, Stadtmauer EA, Estey E, Löwenberg B, Dombret H, Karanes C, Theobald M, Bennett JM, Sherman ML, Berger MS, Eten CB, Loken MR, van Dongen JJ, Bernstein ID, Appelbaum FR. Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse. J Clin Oncol. 2001 Jul 01; 19(13):3244-54. PMID: 11432892.
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    345. Siston AK, List MA, Daugherty CK, Banik DM, Menke C, Cornetta K, Larson RA. Psychosocial adjustment of patients and caregivers prior to allogeneic bone marrow transplantation. Bone Marrow Transplant. 2001 Jun; 27(11):1181-8. PMID: 11551029.
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    346. Mrózek K, Prior TW, Edwards C, Marcucci G, Carroll AJ, Snyder PJ, Koduru PR, Theil KS, Pettenati MJ, Archer KJ, Caligiuri MA, Vardiman JW, Kolitz JE, Larson RA, Bloomfield CD. Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer and Leukemia Group B Study. J Clin Oncol. 2001 May 01; 19(9):2482-92. PMID: 11331327.
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    347. Larson RA. New agents for induction and postremission therapy of acute myeloid leukemia. Leukemia. 2001 Apr; 15(4):675-6. PMID: 11368378.
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    349. Cervini-Silva J, Larson RA, Wu J, Stucki JW. Transformation of chlorinated aliphatic compounds by ferruginous smectite. Environ Sci Technol. 2001 Feb 15; 35(4):805-9. PMID: 11349296.
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    350. Lai F, Godley LA, Joslin J, Fernald AA, Liu J, Espinosa R, Zhao N, Pamintuan L, Till BG, Larson RA, Qian Z, Le Beau MM. Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q). Genomics. 2001 Jan 15; 71(2):235-45. PMID: 11161817.
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    351. Larson R. Children and adolescents in a changing media world. Monogr Soc Res Child Dev. 2001; 66(1):148-54. PMID: 11326590.
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    353. Larson RA. Recent clinical trials in acute lymphocytic leukemia by the Cancer and Leukemia Group B. Hematol Oncol Clin North Am. 2000 Dec; 14(6):1367-79, x. PMID: 11147228.
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    357. Schiffer CA, Miller K, Larson RA, Amrein PC, Antin JH, Zani VJ, Stone RM. A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia. Blood. 2000 Apr 15; 95(8):2530-5. PMID: 10753831.
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    358. Sobecks RM, Daugherty CK, Hallahan DE, Laport GF, Wagner ND, Larson RA. A dose escalation study of total body irradiation followed by high-dose etoposide and allogeneic blood stem cell transplantation for the treatment of advanced hematologic malignancies. Bone Marrow Transplant. 2000 Apr; 25(8):807-13. PMID: 10808200.
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    361. Czuczman MS, Dodge RK, Stewart CC, Frankel SR, Davey FR, Powell BL, Szatrowski TP, Schiffer CA, Larson RA, Bloomfield CD. Value of immunophenotype in intensively treated adult acute lymphoblastic leukemia: cancer and leukemia Group B study 8364. Blood. 1999 Jun 01; 93(11):3931-9. PMID: 10339502.
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    363. Toljanic JA, Bedard JF, Larson RA, Fox JP. A prospective pilot study to evaluate a new dental assessment and treatment paradigm for patients scheduled to undergo intensive chemotherapy for cancer. Cancer. 1999 Apr 15; 85(8):1843-8. PMID: 10223580.
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    364. Finiewicz KJ, Larson RA. Dose-intensive therapy for adult acute lymphoblastic leukemia. Semin Oncol. 1999 Feb; 26(1):6-20. PMID: 10073558.
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    367. Allen RJ, Smith SD, Moldwin RL, Lu MM, Giordano L, Vignon C, Suto Y, Harden A, Tomek R, Veldman T, Ried T, Larson RA, Le Beau MM, Rowley JD, Zeleznik-Le N. Establishment and characterization of a megakaryoblast cell line with amplification of MLL. Leukemia. 1998 Jul; 12(7):1119-27. PMID: 9665199.
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    368. Larson RA, Fretzin MH, Dodge RK, Schiffer CA. Hypersensitivity reactions to L-asparaginase do not impact on the remission duration of adults with acute lymphoblastic leukemia. Leukemia. 1998 May; 12(5):660-5. PMID: 9593262.
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    369. Dann EJ, Anastasi J, Larson RA. High-dose cladribine therapy for chronic myelogenous leukemia in the accelerated or blast phase. J Clin Oncol. 1998 Apr; 16(4):1498-504. PMID: 9552058.
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    370. Lee MY, Jensen E, Kwak S, Larson RA. Metastatic adenocarcinoma arising in a congenital foregut cyst of the esophagus: a case report with review of the literature. Am J Clin Oncol. 1998 Feb; 21(1):64-6. PMID: 9499261.
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    375. Wang P, Spielberger RT, Thangavelu M, Zhao N, Davis EM, Iannantuoni K, Larson RA, Le Beau MM. dic(5;17): a recurring abnormality in malignant myeloid disorders associated with mutations of TP53. Genes Chromosomes Cancer. 1997 Nov; 20(3):282-91. PMID: 9365836.
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    376. Dann EJ, Daugherty CK, Larson RA. Allogeneic bone marrow transplantation for relapsed and refractory Hodgkin's disease and non-Hodgkin's lymphoma. Bone Marrow Transplant. 1997 Sep; 20(5):369-74. PMID: 9339751.
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    378. Sathiakumar N, Delzell E, Amoateng-Adjepong Y, Larson R, Cole P. Epidemiologic evidence on the relationship between mists containing sulfuric acid and respiratory tract cancer. Crit Rev Toxicol. 1997 May; 27(3):233-51. PMID: 9189653.
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    379. Laport GF, Larson RA. Treatment of adult acute lymphoblastic leukemia. Semin Oncol. 1997 Feb; 24(1):70-82. PMID: 9045306.
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    382. Macaluso M, Larson R, Delzell E, Sathiakumar N, Hovinga M, Julian J, Muir D, Cole P. Leukemia and cumulative exposure to butadiene, styrene and benzene among workers in the synthetic rubber industry. Toxicology. 1996 Oct 28; 113(1-3):190-202. PMID: 8901898.
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    384. Le Beau MM, Espinosa R, Davis EM, Eisenbart JD, Larson RA, Green ED. Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases. Blood. 1996 Sep 15; 88(6):1930-5. PMID: 8822909.
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    385. Ong ST, Koeppen H, Larson RA, Olopade OI. Successful treatment of angioimmunoblastic lymphadenopathy with dysproteinemia with fludarabine. Blood. 1996 Sep 15; 88(6):2354-5. PMID: 8822958.
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    386. Anastasi J, Feng J, Dickstein JI, Le Beau MM, Rubin CM, Larson RA, Rowley JD, Vardiman JW. Lineage involvement by BCR/ABL in Ph+ lymphoblastic leukemias: chronic myelogenous leukemia presenting in lymphoid blast vs Ph+ acute lymphoblastic leukemia. Leukemia. 1996 May; 10(5):795-802. PMID: 8656674.
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    387. Thirman MJ, Larson RA. Therapy-related myeloid leukemia. Hematol Oncol Clin North Am. 1996 Apr; 10(2):293-320. PMID: 8707757.
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    390. Larson R, Lee M. The capacity to be alone as a stress buffer. J Soc Psychol. 1996 Feb; 136(1):5-16. PMID: 8851444.
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    393. Ong ST, Larson RA. Current management of acute lymphoblastic leukemia in adults. Oncology (Williston Park). 1995 May; 9(5):433-42; discussion 442-4, 449-50. PMID: 7547204.
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    394. Larson RA, Dodge RK, Burns CP, Lee EJ, Stone RM, Schulman P, Duggan D, Davey FR, Sobol RE, Frankel SR, et al. A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: cancer and leukemia group B study 8811. Blood. 1995 Apr 15; 85(8):2025-37. PMID: 7718875.
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    396. Somani J, Larson RA. Reimmunization after allogeneic bone marrow transplantation. Am J Med. 1995 Apr; 98(4):389-98. PMID: 7709953.
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    397. Joventino LP, Stock W, Lane NJ, Daly KM, Mick R, Le Beau MM, Larson RA. Certain HLA antigens are associated with specific morphologic and cytogenetic subsets of acute myeloid leukemia. Leukemia. 1995 Mar; 9(3):433-9. PMID: 7885042.
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    398. Drinkard LC, Waggoner S, Stein RN, Byrne RA, Larson RA. Acute myelomonocytic leukemia with abnormal eosinophils presenting as an ovarian mass: a report of two cases and a review of the literature. Gynecol Oncol. 1995 Feb; 56(2):307-11. PMID: 7896204.
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    399. Gidal BE, Sorkness CA, McGill KA, Larson R, Levine RR. Evaluation of a potential enantioselective interaction between ticlopidine and warfarin in chronically anticoagulated patients. Ther Drug Monit. 1995 Feb; 17(1):33-8. PMID: 7725374.
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    402. Martinez-Climent JA, Lane NJ, Rubin CM, Morgan E, Johnstone HS, Mick R, Murphy SB, Vardiman JW, Larson RA, Le Beau MM, et al. Clinical and prognostic significance of chromosomal abnormalities in childhood acute myeloid leukemia de novo. Leukemia. 1995 Jan; 9(1):95-101. PMID: 7845034.
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    403. Devine SM, Larson RA. Acute leukemia in adults: recent developments in diagnosis and treatment. CA Cancer J Clin. 1994 Nov-Dec; 44(6):326-52. PMID: 7953914.
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    406. Platanias LC, Ratain MJ, O'Brien S, Larson RA, Vardiman JW, Shaw JP, Williams SF, Baron JM, Parker K, Woodworth TG. Phase I trial of a genetically engineered interleukin-2 fusion toxin (DAB486IL-2) as a 6 hour intravenous infusion in patients with hematologic malignancies. Leuk Lymphoma. 1994 Jul; 14(3-4):257-62. PMID: 7950914.
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    407. Preisler HD, Raza A, Larson R, Goldberg J, Tricot G, Browman G, Bennett J. The relationship of the in vivo cell cycle characteristics and treatment outcome in acute myelogenous leukemia to the expression of the FMS and MYC proto-oncogenes. Leuk Lymphoma. 1994 Jul; 14(3-4):273-8. PMID: 7950916.
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    409. Super HJ, McCabe NR, Thirman MJ, Larson RA, Le Beau MM, Pedersen-Bjergaard J, Philip P, Diaz MO, Rowley JD. Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II. Blood. 1993 Dec 15; 82(12):3705-11. PMID: 8260707.
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    410. Nucifora G, Larson RA, Rowley JD. Persistence of the 8;21 translocation in patients with acute myeloid leukemia type M2 in long-term remission. Blood. 1993 Aug 01; 82(3):712-5. PMID: 8338940.
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    414. Preisler H, Larson R, Banavali S, Yin M, Li YQ, Banerjee M, Gopal V, Raza A. Effects of rhGM-CSF on myeloid clonogenic cells in acute myelogenous leukemia patients. Leuk Lymphoma. 1993 Jun; 10(3):183-6. PMID: 8220116.
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    415. Rabbitts TH, Forster A, Larson R, Nathan P. Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma. Nat Genet. 1993 Jun; 4(2):175-80. PMID: 7503811.
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    416. Lloyd RE, Larson RA, Adair TL, Tuveson RW. Cu(II) sensitizes pBR322 plasmid DNA to inactivation by UV-B (280-315 nm). Photochem Photobiol. 1993 Jun; 57(6):1011-7. PMID: 8367530.
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    417. Raza A, Preisler HD, Browman GP, Larson RA, Rustum YM, Goldberg J, Vogler R, Miller KA, Bennett J, Kukla C. Long-term outcome of patients with acute myelogenous leukemia: the role of maintenance therapy, consolidation therapy and the predictive value of two in vitro assays. Leuk Lymphoma. 1993 May; 10(1-2):57-66. PMID: 8374524.
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    418. Spielberger RT, Falleroni MJ, Coene AJ, Larson RA. Concomitant amphotericin B therapy, granulocyte transfusions, and GM-CSF administration for disseminated infection with Fusarium in a granulocytopenic patient. Clin Infect Dis. 1993 Apr; 16(4):528-30. PMID: 8513060.
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    419. Raza A, Preisler HD, Li YQ, Larson RA, Goldberg J, Browman G, Bennett J, Grunwald H, Vogler R, Kukla C. Biological characteristics of newly diagnosed poor prognosis acute myelogenous leukemia. Am J Hematol. 1993 Apr; 42(4):359-66. PMID: 8493986.
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    420. Spielberger RT, Stock W, Larson RA. Listeriosis after 2-chlorodeoxyadenosine treatment. N Engl J Med. 1993 Mar 18; 328(11):813-4. PMID: 8094890.
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    421. Anastasi J, Feng J, Le Beau MM, Larson RA, Rowley JD, Vardiman JW. Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy, and clone expansion. Blood. 1993 Mar 15; 81(6):1580-5. PMID: 8453104.
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    422. Spielberger RT, Dickstein JI, Le Beau MM, Larson RA, Daly KM, Vardiman JW, Golomb HM. Acute myeloid leukaemia following interferon-alfa treatment of hairy cell leukaemia. Br J Haematol. 1993 Mar; 83(3):519-20. PMID: 8485059.
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    423. Raza A, Yousuf N, Bokhari S, Abbas A, Lampkin B, Pancoast J, Bismayer J, Siegrist C, Browman G, Bennett J, Goldberg J, Grunwald H, Larson R, Tricot G, Vogler R, Gartside P, Preisler H. Cell-cycle characteristics - alterable determinants of remission duration in a study of 179 standard risk newly diagnosed patients with acute myeloid-leukemia. Int J Oncol. 1993 Feb; 2(2):301-7. PMID: 21573555.
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    424. Banavali SD, Pancoast JR, Tricot G, Larson R, Goldberg J, Raza A, Bismayer JA, Preisler HD. The serial study of c-myc expression in bone marrow biopsy specimens during treatment for acute myelogenous leukaemia. Eur J Cancer. 1993; 29A(8):1162-7. PMID: 8518028.
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    425. Westbrook CA, Hooberman AL, Spino C, Dodge RK, Larson RA, Davey F, Wurster-Hill DH, Sobol RE, Schiffer C, Bloomfield CD. Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study (8762). Blood. 1992 Dec 15; 80(12):2983-90. PMID: 1467514.
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    426. Olopade OI, Thangavelu M, Larson RA, Mick R, Kowal-Vern A, Schumacher HR, Le Beau MM, Vardiman JW, Rowley JD. Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia. Blood. 1992 Dec 01; 80(11):2873-82. PMID: 1450412.
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    427. Preisler HD, Raza A, Larson RA. Alteration of the proliferative rate of acute myelogenous leukemia cells in vivo in patients. Blood. 1992 Nov 15; 80(10):2600-3. PMID: 1421377.
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    428. Gradishar WJ, Le Beau MM, O'Laughlin R, Vardiman JW, Larson RA. Clinical and cytogenetic responses to granulocyte-macrophage colony-stimulating factor in therapy-related myelodysplasia. Blood. 1992 Nov 15; 80(10):2463-70. PMID: 1421369.
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    429. Raza A, Gezer S, Anderson J, Lykins J, Bennett J, Browman G, Goldberg J, Larson R, Vogler R, Preisler HD. Relationship of [3H]Ara-C incorporation and response to therapy with high-dose Ara-C in AML patients: a Leukemia Intergroup study. Exp Hematol. 1992 Nov; 20(10):1194-200. PMID: 1426099.
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    430. Barton K, Larson RA, O'Brien S, Ratain MJ. Rapid response of B-cell prolymphocytic leukemia to 2-chlorodeoxyadenosine. J Clin Oncol. 1992 Nov; 10(11):1821. PMID: 1357112.
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    431. Gopal V, Hulette B, Li YQ, Kuvelkar R, Raza A, Larson R, Goldberg J, Tricot G, Bennett J, Preisler H. c-myc and c-myb expression in acute myelogenous leukemia. Leuk Res. 1992 Oct; 16(10):1003-11. PMID: 1405703.
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    432. Larson RA, Day RS, Azarnia N, Bennett JM, Browman G, Goldberg J, Gottlieb A, Grunwald H, Miller K, Raza A, et al. The selective use of AMSA following high-dose cytarabine in patients with acute myeloid leukaemia in relapse: a Leukemia Intergroup study. Br J Haematol. 1992 Oct; 82(2):337-46. PMID: 1419816.
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    433. Myers SE, Devine SM, Topper RL, Ondrey M, Chandler C, O'Toole K, Williams SF, Larson RA, Geller RB. A pilot study of prophylactic aerosolized amphotericin B in patients at risk for prolonged neutropenia. Leuk Lymphoma. 1992 Oct; 8(3):229-33. PMID: 1490149.
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    434. Asthana A, Larson RA, Marley KA, Tuveson RW. Mechanisms of citral phototoxicity. Photochem Photobiol. 1992 Aug; 56(2):211-22. PMID: 1502265.
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    435. Larson RA, Lloyd RE, Marley KA, Tuveson RW. Ferric-ion-photosensitized damage to DNA by hydroxyl and non-hydroxyl radical mechanisms. J Photochem Photobiol B. 1992 Jul 30; 14(4):345-57. PMID: 1403376.
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    436. Larson RA, Le Beau MM, Ratain MJ, Rowley JD. Balanced translocations involving chromosome bands 11q23 and 21q22 in therapy-related leukemia. Blood. 1992 Apr 01; 79(7):1892-3. PMID: 1558980.
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    437. Anastasi J, Le Beau MM, Vardiman JW, Fernald AA, Larson RA, Rowley JD. Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: a simple and sensitive method. Blood. 1992 Apr 01; 79(7):1796-801. PMID: 1558972.
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    438. Neuman WL, Rubin CM, Rios RB, Larson RA, Le Beau MM, Rowley JD, Vardiman JW, Schwartz JL, Farber RA. Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders. Blood. 1992 Mar 15; 79(6):1501-10. PMID: 1347709.
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    439. Schiffer CA, Larson RA, Bloomfield CD. Cancer and Leukemia Group B (CALGB) studies in adult acute lymhocytic leukemia. Leukemia. 1992; 6 Suppl 2:171-4. PMID: 1578925.
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    440. Geller RB, Myers S, Devine S, Larson RA, Williams SF, Park CL, O'Toole K, Chandler C, Topper RL. Phase I study of busulfan, cyclophosphamide, and timed sequential escalating doses of cytarabine followed by bone marrow transplantation. Bone Marrow Transplant. 1992 Jan; 9(1):41-7. PMID: 1543948.
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    441. Preisler HD, Larson RA, Raza A, Browman G, Goldberg J, Vogler R, Day R, Gottlieb A, Vardiman JW, Bennett J, et al. The treatment of patients with newly diagnosed poor prognosis acute myelogenous leukaemia: response to treatment and treatment failure. Br J Haematol. 1991 Nov; 79(3):390-7. PMID: 1751366.
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    442. Preisler HD, Raza A, Kukla C, Larson R, Goldberg J, Browman G. Interleukin-1 beta expression and treatment outcome in acute myelogenous leukemia. Blood. 1991 Aug 01; 78(3):849-50. PMID: 1859896.
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    443. Larson R, Richards MH. Daily companionship in late childhood and early adolescence: changing developmental contexts. Child Dev. 1991 Apr; 62(2):284-300. PMID: 2055123.
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    444. Moormeier JA, Rubin CM, Le Beau MM, Vardiman JW, Larson RA, Winter JN. Trisomy 6: a recurring cytogenetic abnormality associated with marrow hypoplasia. Blood. 1991 Mar 15; 77(6):1397-8. PMID: 2001462.
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    445. Hohl RJ, Larson RA, Mannickarottu V, Yachnin S. Inhibition of hydroxymethylglutaryl coenzyme A reductase activity induces a paradoxical increase in DNA synthesis in myeloid leukemia cells. Blood. 1991 Mar 01; 77(5):1064-70. PMID: 1995091.
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    446. Anastasi J, Thangavelu M, Vardiman JW, Hooberman AL, Bian ML, Larson RA, Le Beau MM. Interphase cytogenetic analysis detects minimal residual disease in a case of acute lymphoblastic leukemia and resolves the question of origin of relapse after allogeneic bone marrow transplantation. Blood. 1991 Mar 01; 77(5):1087-91. PMID: 1995094.
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    447. Geller RB, Larson RA. Therapy for acute myeloid leukemia and acute lymphoblastic leukemia in adults. Curr Opin Oncol. 1991 Feb; 3(1):30-8. PMID: 2043696.
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    448. Larson RA, Lukin CL, Daly KM, Mick R, Gore S, Le Beau MM. Circulating immune complexes correlate with remission duration in acute myeloid leukemia. Leukemia. 1991 Feb; 5(2):131-7. PMID: 2020195.
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    449. Stock W, Larson RA. Neurocysticercosis Coincident with Acute Myeloid Leukemia: A Case Report. Leuk Lymphoma. 1991; 4(2):145-8. PMID: 27462945.
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    450. Preisler H, Raza A, Larson R, Goldberg J, Tricot G, Carey M, Kukla C. Some reasons for the lack of progress in the treatment of acute myelogenous leukemia: a review of three consecutive trials of the treatment of poor prognosis patients. Leuk Res. 1991; 15(9):773-80. PMID: 1921456.
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    451. Rubin CM, Larson RA, Anastasi J, Winter JN, Thangavelu M, Vardiman JW, Rowley JD, Le Beau MM. t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy-related myelodysplastic syndrome and acute myeloid leukemia. Blood. 1990 Dec 15; 76(12):2594-8. PMID: 2265251.
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    452. Platanias LC, Larson RA, Vardiman JW, Reisel H, Golomb HM, McKeithan TW. Complex rearrangement of the T cell receptor in large granular lymphocytosis associated with myeloid suppression. Leukemia. 1990 Dec; 4(12):863-5. PMID: 2173805.
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    453. Thangavelu M, Olopade O, Beckman E, Vardiman JW, Larson RA, McKeithan TW, Le Beau MM, Rowley JD. Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11). Genes Chromosomes Cancer. 1990 Jul; 2(2):147-58. PMID: 2278969.
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    454. Sato H, Preisler H, Day R, Raza A, Larson R, Browman G, Goldberg J, Vogler R, Grunwald H, Gottlieb A, et al. MDR1 transcript levels as an indication of resistant disease in acute myelogenous leukaemia. Br J Haematol. 1990 Jul; 75(3):340-5. PMID: 1696833.
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    455. Kaminer LS, Choi KE, Daley KM, Larson RA. Continuous infusion mitoxantrone in relapsed acute nonlymphocytic leukemia. Cancer. 1990 Jun 15; 65(12):2619-23. PMID: 2340463.
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    456. Bitter MA, Franklin WA, Larson RA, McKeithan TW, Rubin CM, Le Beau MM, Stephens JK, Vardiman JW. Morphology in Ki-1(CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35). Am J Surg Pathol. 1990 Apr; 14(4):305-16. PMID: 2157342.
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    457. Olopade OI, Larson RA, Mick R, Watson SM, Hoffman PC, Ultmann JE, Golomb HM. Long-term survival of patients with intermediate and high grade lymphoma treated with COMLA/ABP. Leukemia. 1990 Feb; 4(2):127-31. PMID: 1689439.
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    458. Diaz MO, Rubin CM, Harden A, Ziemin S, Larson RA, Le Beau MM, Rowley JD. Deletions of interferon genes in acute lymphoblastic leukemia. N Engl J Med. 1990 Jan 11; 322(2):77-82. PMID: 2294436.
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    459. Strauss B, Sagher D, Karrison T, Schwartz J, Larson R, Williams S. Methyl transferase activity in secondary leukemia. Basic Life Sci. 1990; 53:277-89. PMID: 2177980.
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    460. Platanias LC, Larson RA, Anastasi J, Golomb HM. Relapse of Hodgkin's Disease After 14 Years of Complete Remission. Leuk Lymphoma. 1990; 3(3):223-6. PMID: 27457442.
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    461. Le Beau MM, Bitter MA, Larson RA, Doane LA, Ellis ED, Franklin WA, Rubin CM, Kadin ME, Vardiman JW. The t(2;5)(p23;q35): a recurring chromosomal abnormality in Ki-1-positive anaplastic large cell lymphoma. Leukemia. 1989 Dec; 3(12):866-70. PMID: 2555633.
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    462. Williams SF, Larson RA. Hypersensitivity reaction to high-dose cytarabine. Br J Haematol. 1989 Oct; 73(2):274-5. PMID: 2530999.
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    463. Larson R, Lampman-Petraitis C. Daily emotional states as reported by children and adolescents. Child Dev. 1989 Oct; 60(5):1250-60. PMID: 2805902.
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    464. Sagher D, Karrison T, Schwartz JL, Larson RA, Strauss B. Heterogeneity of O6-alkylguanine-DNA alkyltransferase activity in peripheral blood lymphocytes: relationship between this activity in lymphocytes and in lymphoblastoid lines from normal controls and from patients with Hodgkin's disease or non-Hodgkin's lymphoma. Cancer Res. 1989 Oct 01; 49(19):5339-44. PMID: 2548719.
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    465. Schwartz JL, Karrison T, Le Beau MM, Larson RA, Sagher D, Strauss B, Rowley JD, Weichselbaum RR. Chromosomal sensitivity of lymphocytes from individuals with therapy-related acute nonlymphocytic leukemia. Mutat Res. 1989 Apr; 216(2):119-26. PMID: 2494444.
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    466. Le Beau MM, Lemons RS, Espinosa R, Larson RA, Arai N, Rowley JD. Interleukin-4 and interleukin-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q). Blood. 1989 Feb 15; 73(3):647-50. PMID: 2783863.
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    467. Raimondi SC, Dubé ID, Valentine MB, Mirro J, Watt HJ, Larson RA, Bitter MA, Le Beau MM, Rowley JD. Clinicopathologic manifestations and breakpoints of the t(3;5) in patients with acute nonlymphocytic leukemia. Leukemia. 1989 Jan; 3(1):42-7. PMID: 2642576.
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    468. Preisler HD, Raza A, Larson R, LeBeau M, Browman G, Goldberg J, Grunwald H, Volger R, Verkh L, Singh P, et al. Protooncogene expression and the clinical characteristics of acute nonlymphocytic leukemia: A Leukemia Intergroup pilot study. Blood. 1989 Jan; 73(1):255-62. PMID: 2910363.
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    469. Thangavelu M, Bitter MA, Larson RA, Davis EM, Rowley JD, Le Beau MM. Der(5)t(5;7)(q11.2;p11.2): a new recurring abnormality in malignant myeloid disorders. Cancer Genet Cytogenet. 1989 Jan; 37(1):1-8. PMID: 2917326.
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    470. Larson RA, Marley KA, Tuveson RW, Berenbaum MR. Beta-carboline alkaloids: mechanisms of phototoxicity to bacteria and insects. Photochem Photobiol. 1988 Nov; 48(5):665-74. PMID: 3071812.
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    471. Li YS, Anastasi J, Larson RA, Le Beau MM, Vardiman JW, Rowley JD. A recurring chromosome rearrangement, dic(16;22), in acute nonlymphocytic leukemia. Cancer Genet Cytogenet. 1988 Oct 15; 35(2):143-50. PMID: 3180017.
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    472. Larson RA, Wernli M, Le Beau MM, Daly KM, Pape LH, Rowley JD, Vardiman JW. Short remission durations in therapy-related leukemia despite cytogenetic complete responses to high-dose cytarabine. Blood. 1988 Oct; 72(4):1333-9. PMID: 3167210.
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    473. Larson R. The high school "Junior Theme" as an adolescent rite of passage. J Youth Adolesc. 1988 Aug; 17(4):267-83. PMID: 24277647.
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    474. Shepard KV, Larson R, Le Beau MM, Leichman L, Levin B. Acute leukemia occurring after radiotherapy and chemotherapy with a nitrosourea, PCNU. Invest New Drugs. 1988 Jun; 6(2):121-4. PMID: 3170132.
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    475. Sagher D, Karrison T, Schwartz JL, Larson R, Meier P, Strauss B. Low O6-alkylguanine DNA alkyltransferase activity in the peripheral blood lymphocytes of patients with therapy-related acute nonlymphocytic leukemia. Cancer Res. 1988 Jun 01; 48(11):3084-9. PMID: 2452685.
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    476. Daiter S, Larson RA, Weddington WW, Ultmann JE. Psychosocial symptomatology, personal growth, and development among young adult patients following the diagnosis of leukemia or lymphoma. J Clin Oncol. 1988 Apr; 6(4):613-7. PMID: 3357005.
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    477. Robertson MJ, Larson RA. Recurrent fungal pneumonias in patients with acute nonlymphocytic leukemia undergoing multiple courses of intensive chemotherapy. Am J Med. 1988 Feb; 84(2):233-9. PMID: 3407652.
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    478. Rippon JW, Larson RA, Rosenthal DM, Clayman J. Disseminated cutaneous and peritoneal hyalohyphomycosis caused by Fusarium species: three cases and review of the literature. Mycopathologia. 1988 Feb; 101(2):105-11. PMID: 3278237.
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    479. Samuels BL, Larson RA, Le Beau MM, Daly KM, Bitter MA, Vardiman JW, Barker CM, Rowley JD, Golomb HM. Specific chromosomal abnormalities in acute nonlymphocytic leukemia correlate with drug susceptibility in vivo. Leukemia. 1988 Feb; 2(2):79-83. PMID: 3343866.
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    480. Dalton DP, Rushovich AM, Victor TA, Larson R. Leiomyosarcoma of the scrotum in a man who had received scrotal irradiation as a child. J Urol. 1988 Jan; 139(1):136-8. PMID: 3275795.
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    481. Rubin CM, Larson RA, Bitter MA, Carrino JJ, Le Beau MM, Diaz MO, Rowley JD. Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia. Blood. 1987 Nov; 70(5):1338-42. PMID: 3478099.
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    482. Ratain MJ, Kaminer LS, Bitran JD, Larson RA, Le Beau MM, Skosey C, Purl S, Hoffman PC, Wade J, Vardiman JW, et al. Acute nonlymphocytic leukemia following etoposide and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung. Blood. 1987 Nov; 70(5):1412-7. PMID: 2822173.
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    483. Choi KE, Sinkule JA, Han DS, McGrath SC, Daly KM, Larson RA. High-performance liquid chromatographic assay for mitoxantrone in plasma using electrochemical detection. J Chromatogr. 1987 Sep 04; 420(1):81-8. PMID: 3667832.
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    484. Frankel DH, Larson RA, Lorincz AL. Acral lividosis--a sign of myeloproliferative diseases. Hyperleukocytosis syndrome in chronic myelogenous leukemia. Arch Dermatol. 1987 Jul; 123(7):921-4. PMID: 3475043.
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    485. Pettenati MJ, Le Beau MM, Lemons RS, Shima EA, Kawasaki ES, Larson RA, Sherr CJ, Diaz MO, Rowley JD. Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders. Proc Natl Acad Sci U S A. 1987 May; 84(9):2970-4. PMID: 3495006.
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    486. Bitter MA, Le Beau MM, Rowley JD, Larson RA, Golomb HM, Vardiman JW. Associations between morphology, karyotype, and clinical features in myeloid leukemias. Hum Pathol. 1987 Mar; 18(3):211-25. PMID: 3546071.
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    487. Larson RA, Daly KM, Choi KE, Han DS, Sinkule JA. A clinical and pharmacokinetic study of mitoxantrone in acute nonlymphocytic leukemia. J Clin Oncol. 1987 Mar; 5(3):391-7. PMID: 3546616.
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    488. Preisler HD, Raza A, Barcos M, Azarnia N, Larson R, Walker I, Browman M, Grunwald H, D'Arrigo P, Doeblin T, et al. High-dose cytosine arabinoside as the initial treatment of poor-risk patients with acute nonlymphocytic leukemia: a Leukemia Intergroup Study. J Clin Oncol. 1987 Jan; 5(1):75-82. PMID: 3806162.
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    489. Larson RA, Williams SF, Le Beau MM, Bitter MA, Vardiman JW, Rowley JD. Acute myelomonocytic leukemia with abnormal eosinophils and inv(16) or t(16;16) has a favorable prognosis. Blood. 1986 Dec; 68(6):1242-9. PMID: 3465376.
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    490. Preisler HD, Raza A, Barcos M, Azarnia N, Larson R, Browman G, Walker I, Grunwald H, D'Arrigo P, Stein A, et al. High-dose cytosine arabinoside in the treatment of preleukemic disorders: a leukemia intergroup study. Am J Hematol. 1986 Oct; 23(2):131-4. PMID: 3529939.
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    491. Slamon DJ, Boone TC, Murdock DC, Keith DE, Press MF, Larson RA, Souza LM. Studies of the human c-myb gene and its product in human acute leukemias. Science. 1986 Jul 18; 233(4761):347-51. PMID: 3014652.
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    492. Jacobs RH, Cornbleet MA, Vardiman JW, Larson RA, Le Beau MM, Rowley JD. Prognostic implications of morphology and karyotype in primary myelodysplastic syndromes. Blood. 1986 Jun; 67(6):1765-72. PMID: 3708160.
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    493. Fattore L, Larson RA, Mostofi RS. Dental management of cancer patients receiving chemotherapy. IMJ Ill Med J. 1986 Apr; 169(4):223-7. PMID: 2870997.
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    494. Larson RA. Insect defenses against phototoxic plant chemicals. J Chem Ecol. 1986 Apr; 12(4):859-70. PMID: 24306974.
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    495. Le Beau MM, Albain KS, Larson RA, Vardiman JW, Davis EM, Blough RR, Golomb HM, Rowley JD. Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7. J Clin Oncol. 1986 Mar; 4(3):325-45. PMID: 3950675.
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    496. Le Beau MM, Westbrook CA, Diaz MO, Larson RA, Rowley JD, Gasson JC, Golde DW, Sherr CJ. Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders. Science. 1986 Feb 28; 231(4741):984-7. PMID: 3484837.
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    497. Preisler HD, Raza A, Larson R, Browman G, Goldberg J, Grunwald H, Vogler R, Bennett J, Gottlieb A, D'Arrigo P. Limited efficacy of a four-day course of high-dose cytosine arabinoside in the treatment of poor-risk patients with acute nonlymphocytic leukemia. Cancer Chemother Pharmacol. 1986; 18(3):257-60. PMID: 3802381.
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    498. Le Beau MM, Pettenati MJ, Lemons RS, Diaz MO, Westbrook CA, Larson RA, Sherr CJ, Rowley JD. Assignment of the GM-CSF, CSF-1, and FMS genes to human chromosome 5 provides evidence for linkage of a family of genes regulating hematopoiesis and for their involvement in the deletion (5q) in myeloid disorders. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt 2:899-909. PMID: 3495397.
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    499. Larson RA, Gaynor ER, Shepard KV, Daly KM. High-dose Ara-C plus VM-26 in adult acute lymphoblastic leukemia. Eur J Cancer Clin Oncol. 1985 Oct; 21(10):1261-3. PMID: 3865776.
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    500. Winter JN, Variakojis D, Gaynor ER, Larson RA, Miller KB. Low-dose cytosine arabinoside (Ara-C) therapy in the myelodysplastic syndromes and acute leukemia. Cancer. 1985 Aug 01; 56(3):443-9. PMID: 3859362.
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    501. Larson RA. Management of myelodysplastic syndromes. Ann Intern Med. 1985 Jul; 103(1):136-8. PMID: 4003970.
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    502. Rippon JW, Arnow PM, Larson RA, Zang KL. 'Golden tongue' syndrome caused by Ramichloridium schulzeri. Arch Dermatol. 1985 Jul; 121(7):892-4. PMID: 3860191.
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    503. Kotake AN, Vogelzang NJ, Larson RA, Choporis N. New high-performance liquid chromatographic assay for plasma doxorubicin. J Chromatogr. 1985 Jan 11; 337(1):194-200. PMID: 3980653.
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    504. Larson R, Johnson C. Bulimia: disturbed patterns of solitude. Addict Behav. 1985; 10(3):281-90. PMID: 3866486.
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    505. Pegues DA, Daly KM, Larson RA. Use of decline in D-xylose absorption to predict infection following intensive chemotherapy. Cancer Treat Rep. 1984 Dec; 68(12):1489-91. PMID: 6509454.
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    506. Larson RA, Kluskens LE, Yachnin S. The DNA synthetic response of normal and abnormal human lymphocytes to mevalonic acid: the role of granulocytes as a helper population. J Allergy Clin Immunol. 1984 Sep; 74(3 Pt 1):280-90. PMID: 6236250.
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    507. Larson RA, Yachnin S. Mevalonic acid induces DNA synthesis in chronic lymphocytic leukemia cells. Blood. 1984 Jul; 64(1):257-62. PMID: 6610447.
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    508. Larson R, Csikszentmihalyi M, Freeman M. Alcohol and marijuana use in adolescents' daily lives: a random sample of experiences. Int J Addict. 1984 Jul; 19(4):367-81. PMID: 6480170.
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    509. Bitter MA, Le Beau MM, Larson RA, Rosner MC, Golomb HM, Rowley JD, Vardiman JW. A morphologic and cytochemical study of acute myelomonocytic leukemia with abnormal marrow eosinophils associated with inv(16)(p13q22). Am J Clin Pathol. 1984 Jun; 81(6):733-41. PMID: 6203400.
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    510. Larson RA, Kondo K, Vardiman JW, Butler AE, Golomb HM, Rowley JD. Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia. Am J Med. 1984 May; 76(5):827-41. PMID: 6586073.
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    511. Jacobs RH, Larson RA, LeBeau M, Kluskens LF, Vardiman JW, Rowley JD, Golomb HM. Hypercalcemia and lytic bone lesions in a patient with B-cell non-Hodgkin's lymphoma. N Engl J Med. 1984 Jan 26; 310(4):263-4. PMID: 6318111.
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    512. Larson RA, Le Beau MM, Vardiman JW, Testa JR, Golomb HM, Rowley JD. The predictive value of initial cytogenetic studies in 148 adults with acute nonlymphocytic leukemia: a 12-year study (1970-1982). Cancer Genet Cytogenet. 1983 Nov; 10(3):219-36. PMID: 6627222.
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    513. Larson RA, Gordon LI, Yachnin S. Neutrophil-assisted DNA synthesis by human lymphocytes in response to mevalonic acid; enhancement by cytochalasin B. Cell Immunol. 1983 Oct 15; 81(2):357-72. PMID: 6640672.
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    514. Larson RA, Yachnin S. Cytochalasin B is a potent mitogen for chronic lymphocytic leukemia cells in vitro. J Clin Invest. 1983 Oct; 72(4):1268-76. PMID: 6630510.
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    515. Le Beau MM, Larson RA, Bitter MA, Vardiman JW, Golomb HM, Rowley JD. Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association. N Engl J Med. 1983 Sep 15; 309(11):630-6. PMID: 6577285.
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    516. Yachnin S, Larson RA, West EJ. Rates of cholesterol biosynthesis are related to early differentiation in acute non-lymphocytic leukaemia cells. Br J Haematol. 1983 Jul; 54(3):459-66. PMID: 6574789.
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    517. Hoffman PC, Richman CM, Larson RA, Yachnin S. Cholesterol and mevalonic acid are independent requirements for the in vitro proliferation of human bone marrow granulocyte progenitor cells: studies using ML-236B. Blood. 1983 Apr; 61(4):667-71. PMID: 6831033.
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    518. Kaneko Y, Larson RA, Variakojis D, Haren JM, Rowley JD. Nonrandom chromosome abnormalities in angioimmunoblastic lymphadenopathy. Blood. 1982 Oct; 60(4):877-87. PMID: 6180784.
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    519. Larson RA, Sweet DL, Golomb HM, Testa JR, Rowley JD. Response to 5-azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings. Cancer. 1982 Jun 01; 49(11):2222-5. PMID: 6176310.
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    520. Larson RA, Chung J, Scanu AM, Yachnin S. Neutrophils are required for the DNA synthetic response of human lymphocytes to mevalonic acid: evidence suggesting that a nonsterol product of mevalonate is involved. Proc Natl Acad Sci U S A. 1982 May; 79(9):3028-32. PMID: 6953445.
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    521. Larson RA, Ultmann JE. The strategic role of laparotomy in staging Hodgkin's disease. Cancer Treat Rep. 1982 Apr; 66(4):767-74. PMID: 7074647.
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    522. Larson R, Johnson C. Anorexia nervosa in the context of daily experience. J Youth Adolesc. 1981 Dec; 10(6):455-71. PMID: 24310538.
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    523. Larson RA, Golomb HM, Rowley JD. Chromosome changes in hematologic malignancies. CA Cancer J Clin. 1981 Jul-Aug; 31(4):222-38. PMID: 6796217.
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