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Julian Solway

TitleProfessor
InstitutionUniversity of Chicago
DepartmentMedicine-Pulmonary and Critical Care
AddressChicago IL 60637
Email
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    Collapse Overview 
    Collapse overview
    Walter L. Palmer Distinguished Service Professor of Medicine and Pediatrics
    Dean for Translational Medicine
    Director, Institute for Translational Medicine

    I am Dean for Translational Medicine and founding Director of the Institute for Translational Medicine, home of the University of Chicago-Rush University NIH/NCATS CTSA award. I have served the CTSA Consortium as a co-Chair, Steering Committee member, and co-Chair of the Strategic Goal 3 and Collaboration/Engagement Domain Task Force. My research programs primarily address asthma. I have extensive experience studying airway smooth muscle (ASM) function and dysfunction in asthma, having studied smooth muscle specific gene transcription, protein accumulation, and hypertrophy, and signaling mechanisms that regulate these; ASM contraction and its reversal, and the mechanisms that regulate these; and ASM mediated-airway narrowing, airway constrictor responsiveness, and lung function in both animal models and humans. Additional studies address asthma genetics and therapeutics in mechanistic and therapeutic clinical studies and preclinical development of novel asthma treatments. Recently, I have focused on the inhibition of pulmonary fibrosis and on the inhibition of breast cancer metastasis using novel small molecules discovered in our asthma studies. I directed the University of Chicago's NHLBI-sponsored T32 Research Training Program in Respiratory Biology for 25 years, led or co-led two NHLBI Multidisciplinary K12 Training Programs, co-led an NIH Broadening Experiences in Scientific Training (BEST) award, and currently lead a Burroughs Wellcome Fund Physician Scientist Institutional Award.

    My ORCID is 0000-0002-0898-8530.
    My Scopus ID is 7006796752.
    My NIH COMMONS name is jsolway.

    BS 1974 Massachusetts Institute of Technology (Electrical Engineering)
    MD cum laude 1978 Harvard University (Medicine)
    Residency 1981 Brigham and Women's Hospital (Internal Medicine)
    Fellowship 1983 Harvard Medical School (Pulmonary Medicine)

    Collapse Biography 
    Collapse awards and honors
    1973Tau Beta Pi
    1973Eta Kappa Nu
    1991American Society for Clinical Investigation
    2001ACP-ASIM Award for Outstanding Work in Science as Related to Medicine
    2005Association of American Physicians
    2008UChicago Dept of Medicine Arthur H. Rubenstein Mentorship Award
    2010Joseph R. Rodarte Award for Scientific Distinction, Am Thoracic Soc Resp Struct & Function Assembly
    2020American Thoracic Society Recognition Award for Scientific Accomplishment
    2021UChicago Dept of Medicine Distinguished Service Award

    Collapse Research 
    Collapse research activities and funding
    R21AI163645     (SOLWAY, JULIAN)Nov 8, 2022 - Oct 31, 2024
    NIH
    Smooth Muscle Myosin PROTACs as a Novel Treatment for Asthma
    Role: Principal Investigator
    UG1HL139125     (ROSENBERG, SHARON R.;WHITE, STEVEN R)Sep 23, 2017 - Jun 30, 2023
    NIH
    Chicago Metropolitan Asthma Consortium for severe / exacerbation-prone asthma
    Role: Co-Investigator
    UL1TR002389     (SOLWAY, JULIAN)Sep 6, 2017 - Jun 30, 2027
    NIH
    The Institute for Translational Medicine
    Role: Multiple PI (Contact)
    U54MD010723     (PERERA, MINOLI)Aug 19, 2016 - May 31, 2021
    NIH
    African American Cardiovascular pharmacogenetic CONsorTium (ACCOuNT): discovery and translation
    Role: Co-Investigator
    UG3OD023189     (GREENLAND, PHILIP)Jul 6, 2016 - May 31, 2018
    NIH
    Illinois Precision Medicine Consortium (IPMC)
    Role: Co-Investigator
    R01HL122712     (SOLWAY, JULIAN)Sep 1, 2015 - Jun 30, 2020
    NIH
    Mendelian Disease - Asthma Comorbidity to Find Subgroup-Specific Asthma Genes
    Role: Multiple PI (Contact)
    UH3HL123816     (SOLWAY, JULIAN)Sep 22, 2014 - Jun 30, 2019
    NIH
    Preclinical development of myosolvins, a new class of medicine for asthma
    Role: Multiple PI (Contact)
    DP7OD020316     (ADAMS, ERIN JUNE)Sep 18, 2014 - Aug 31, 2021
    NIH
    MyChoice
    Role: Multiple PI
    R01HL113395     (THOMPSON, EMMA E)Mar 1, 2014 - Feb 29, 2020
    NIH
    Dissecting the Genetic Architecture of Airway Hyperresponsiveness
    Role: Co-Investigator
    T32HL007605     (MUTLU, GOKHAN M.)Jun 1, 1985 - Jun 30, 2025
    NIH
    Research training in respiratory biology
    Role: Multiple PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Thakur A, Mei S, Zhang N, Zhang K, Taslakjian B, Lian J, Wu S, Chen B, Solway J, Chen HJ. Pulmonary neuroendocrine cells: crucial players in respiratory function and airway-nerve communication. Front Neurosci. 2024; 18:1438188. PMID: 39176384; PMCID: PMC11340541.
      Citations:    
    2. Gobbi A, Antonelli A, Dellaca R, Pellegrino GM, Pellegrino R, Fredberg JJ, Solway J, Brusasco V. Effects of increasing tidal volume and end-expiratory lung volume on induced bronchoconstriction in healthy humans. Respir Res. 2024 Aug 07; 25(1):298. PMID: 39113017; PMCID: PMC11304934.
      Citations:    Fields:    Translation:Humans
    3. Tilmon S, Nyenhuis S, Solomonides A, Barbarioli B, Bhargava A, Birz S, Bouzein K, Cardenas C, Carlson B, Cohen E, Dillon E, Furner B, Huang Z, Johnson J, Krishnan N, Lazenby K, Li K, Makhni S, Miller D, Ozik J, Santos C, Sleiman M, Solway J, Krishnan S, Volchenbouma S. Erratum: Sociome Data Commons: A scalable and sustainable platform for investigating the full social context and determinants of health - ERRATUM. J Clin Transl Sci. 2024; 8(1):e82. PMID: 38745878; PMCID: PMC11091915.
      Citations:    
    4. Reed EB, Orbeta S, Miao BA, Sitikov A, Chen B, Levitan I, Solway J, Mutlu GM, Fang Y, Mongin AA, Dulin NO. Anoctamin-1 is induced by TGF-ß and contributes to lung myofibroblast differentiation. Am J Physiol Lung Cell Mol Physiol. 2024 01 01; 326(1):L111-L123. PMID: 38084409; PMCID: PMC11279757.
      Citations:    Fields:    Translation:HumansCells
    5. Mirmira RG, Kulkarni RN, Xu P, Drossos T, Varady K, Knutson KL, Reutrakul S, Martyn-Nemeth P, Sargis RM, Wallia A, Tuchman AM, Weissberg-Benchell J, Danielson KK, Oakes SA, Thomas CC, Layden BT, May SC, Burbea Hoffmann M, Gatta E, Solway J, Philipson LH. Stress and human health in diabetes: A report from the 19th Chicago Biomedical Consortium symposium. J Clin Transl Sci. 2023; 7(1):e263. PMID: 38229904; PMCID: PMC10790105.
      Citations:    
    6. Suver C, Harper J, Loomba J, Saltz M, Solway J, Anzalone AJ, Walters K, Pfaff E, Walden A, McMurry J, Chute CG, Haendel M. The N3C governance ecosystem: A model socio-technical partnership for the future of collaborative analytics at scale. J Clin Transl Sci. 2023; 7(1):e252. PMID: 38229902; PMCID: PMC10789985.
      Citations:    
    7. Reed EB, Orbeta S, Sitikov A, Levitan I, Mutlu GM, Dulin NO, Miao BA, Chen B, Solway J, Fang Y, Mongin AA. Anoctamin-1 is induced by TGF-beta and contributes to lung myofibroblast differentiation. bioRxiv. 2023 Nov 09. PMID: 37333255; PMCID: PMC10274757.
      Citations:    
    8. Tilmon S, Nyenhuis S, Solomonides A, Barbarioli B, Bhargava A, Birz S, Bouzein K, Cardenas C, Carlson B, Cohen E, Dillon E, Furner B, Huang Z, Johnson J, Krishnan N, Lazenby K, Li K, Makhni S, Miler D, Ozik J, Santos C, Sleiman M, Solway J, Krishnan S, Volchenboum S. Sociome Data Commons: A scalable and sustainable platform for investigating the full social context and determinants of health. J Clin Transl Sci. 2023; 7(1):e255. PMID: 38229897; PMCID: PMC10789989.
      Citations: 1     
    9. Adegunsoye A, Baccile R, Best TJ, Zaksas V, Zhang H, Karnik R, Patel BK, Solomonides AE, Parker WF, Solway J. Pharmacotherapy and pulmonary fibrosis risk after SARS-CoV-2 infection-response to Guangting Zeng and Yuchi Zhou. Lancet Reg Health Am. 2023 Oct; 26:100611. PMID: 37829195; PMCID: PMC10565760.
      Citations:    
    10. Adegunsoye A, Baccile R, Best TJ, Zaksas V, Zhang H, Karnik R, Patel BK, Solomonides AE, Parker WF, Solway J, N3C Consortium. Pharmacotherapy and pulmonary fibrosis risk after SARS-CoV-2 infection: a prospective nationwide cohort study in the United States. Lancet Reg Health Am. 2023 Sep; 25:100566. PMID: 37564420; PMCID: PMC10410516.
      Citations: 5     
    11. Jia G, Zhong X, Im HK, Schoettler N, Pividori M, Hogarth DK, Sperling AI, White SR, Naureckas ET, Lyttle CS, Terao C, Kamatani Y, Akiyama M, Matsuda K, Kubo M, Cox NJ, Ober C, Rzhetsky A, Solway J. Discerning asthma endotypes through comorbidity mapping. Nat Commun. 2022 11 07; 13(1):6712. PMID: 36344522; PMCID: PMC9640644.
      Citations: 7     Fields:    Translation:Humans
    12. Solway J, Kenyon N, Berglund L. Clinical and translational science and climate change: Time for action. J Clin Transl Sci. 2022; 6(1):e57. PMID: 35720971; PMCID: PMC9161039.
      Citations: 2     
    13. Deer RR, Rock MA, Vasilevsky N, Carmody L, Rando H, Anzalone AJ, Basson MD, Bennett TD, Bergquist T, Boudreau EA, Bramante CT, Byrd JB, Callahan TJ, Chan LE, Chu H, Chute CG, Coleman BD, Davis HE, Gagnier J, Greene CS, Hillegass WB, Kavuluru R, Kimble WD, Koraishy FM, Liang C, Liu F, Liu H, Madhira V, Madlock-Brown CR, Matentzoglu N, Mazzotti DR, McMurry JA, McNair DS, Moffitt RA, Monteith TS, Parker AM, Perry MA, Pfaff E, Reese JT, Saltz J, Schuff RA, Solomonides AE, Solway J, Spratt H, Stein GS, Sule AA, Topaloglu U, Vavougios GD, Wang L, Haendel MA, Robinson PN, Köhler S. Characterizing Long COVID: Deep Phenotype of a Complex Condition. EBioMedicine. 2021 Dec; 74:103722. PMID: 34839263; PMCID: PMC8613500.
      Citations: 96     Fields:    Translation:HumansCells
    14. Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, Cardet JC, Castro M, Denlinger LC, Eng C, Fitzpatrick AM, Holguin F, Hu D, Jackson DJ, Jarjour N, Kraft M, Krishnan JA, Lazarus SC, Lemanske RF, Lima JJ, Lugogo N, Mak A, Moore WC, Naureckas ET, Peters SP, Pongracic JA, Sajuthi SP, Seibold MA, Smith LJ, Solway J, Sorkness CA, Wenzel S, White SR, Burchard EG, Barnes K, Meyers DA, Israel E, Wechsler ME, NHLBI AsthmaNet. Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma. Lancet Child Adolesc Health. 2021 12; 5(12):862-872. PMID: 34762840; PMCID: PMC8787857.
      Citations: 8     Fields:    Translation:Humans
    15. McElvaine AT, Hawkins-Salsbury JA, Arora VM, Gladwin MT, Goldenring JR, Huston DP, Krakow D, Rhee K, Solway J, Steinman RA, Towler DA, Utz PJ, Yokoyama WM, Simpson RL, Muglia LJ, Permar SR, Gbadegesin RA. Innovations in MD-only physician-scientist training: experiences from the Burroughs Wellcome Fund physician-scientist institutional award initiative. J Clin Invest. 2021 05 17; 131(10). PMID: 33998594; PMCID: PMC8121502.
      Citations: 5     Fields:    Translation:Humans
    16. Meltzer DO, Best TJ, Zhang H, Vokes T, Arora VM, Solway J. Association of Vitamin D Levels, Race/Ethnicity, and Clinical Characteristics With COVID-19 Test Results. JAMA Netw Open. 2021 03 01; 4(3):e214117. PMID: 33739433; PMCID: PMC7980095.
      Citations: 35     Fields:    Translation:HumansCells
    17. Clougherty JE, Kinnee EJ, Cardet JC, Mauger D, Bacharier L, Beigelman A, Blake KV, Cabana MD, Castro M, Chmiel JF, Covar R, Fitzpatrick A, Gaffin JM, Gentile D, Israel E, Jackson DJ, Kraft M, Krishnan JA, Kumar HV, Lang JE, Lazarus SC, Lemanske RF, Lima J, Martinez FD, Morgan W, Moy J, Myers R, Naureckas ET, Ortega VE, Peters SP, Phipatanakul W, Pongracic JA, Ross K, Sheehan WJ, Smith LJ, Solway J, Sorkness CA, Wechsler ME, Wenzel S, White SR, Holguin F. Geography, generalisability, and susceptibility in clinical trials. Lancet Respir Med. 2021 04; 9(4):330-332. PMID: 33539731; PMCID: PMC8009610.
      Citations: 5     Fields:    Translation:Humans
    18. Meltzer DO, Best TJ, Zhang H, Vokes T, Arora V, Solway J. Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results. JAMA Netw Open. 2020 09 01; 3(9):e2019722. PMID: 32880651; PMCID: PMC7489852.
      Citations: 245     Fields:    Translation:HumansCellsPHPublic Health
    19. Thompson EE, Dang Q, Mitchell-Handley B, Rajendran K, Ram-Mohan S, Solway J, Ober C, Krishnan R. Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma. Genome Med. 2020 07 20; 12(1):64. PMID: 32690065; PMCID: PMC7370514.
      Citations: 8     Fields:    Translation:HumansCells
    20. Yeung BHY, Huang J, An SS, Solway J, Mitzner W, Tang WY. Role of Isocitrate Dehydrogenase 2 on DNA Hydroxymethylation in Human Airway Smooth Muscle Cells. Am J Respir Cell Mol Biol. 2020 07; 63(1):36-45. PMID: 32150688; PMCID: PMC7328249.
      Citations: 11     Fields:    Translation:HumansCells
    21. Meltzer DO, Best TJ, Zhang H, Vokes T, Arora V, Solway J. Association of Vitamin D Deficiency and Treatment with COVID-19 Incidence. medRxiv. 2020 May 13. PMID: 32511549; PMCID: PMC7274230.
      Citations: 2     
    22. Ram-Mohan S, Bai Y, Schaible N, Ehrlicher AJ, Cook DP, Suki B, Stoltz DA, Solway J, Ai X, Krishnan R. Tissue traction microscopy to quantify muscle contraction within precision-cut lung slices. Am J Physiol Lung Cell Mol Physiol. 2020 02 01; 318(2):L323-L330. PMID: 31774304; PMCID: PMC7052683.
      Citations: 9     Fields:    Translation:HumansAnimals
    23. Wechsler ME, Szefler SJ, Ortega VE, Pongracic JA, Chinchilli V, Lima JJ, Krishnan JA, Kunselman SJ, Mauger D, Bleecker ER, Bacharier LB, Beigelman A, Benson M, Blake KV, Cabana MD, Cardet JC, Castro M, Chmiel JF, Covar R, Denlinger L, DiMango E, Fitzpatrick AM, Gentile D, Grossman N, Holguin F, Jackson DJ, Kumar H, Kraft M, LaForce CF, Lang J, Lazarus SC, Lemanske RF, Long D, Lugogo N, Martinez F, Meyers DA, Moore WC, Moy J, Naureckas E, Olin JT, Peters SP, Phipatanakul W, Que L, Raissy H, Robison RG, Ross K, Sheehan W, Smith LJ, Solway J, Sorkness CA, Sullivan-Vedder L, Wenzel S, White S, Israel E, NHLBI AsthmaNet. Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma. N Engl J Med. 2019 09 26; 381(13):1227-1239. PMID: 31553835; PMCID: PMC7026584.
      Citations: 20     Fields:    Translation:Humans
    24. Feldmeth G, Lindau ST, Naureckas ET, Solway J. Embedding research recruitment in a community resource e-prescribing system: lessons from an implementation study on Chicago's South Side. J Am Med Inform Assoc. 2019 08 01; 26(8-9):840-846. PMID: 31181137; PMCID: PMC7587152.
      Citations: 6     Fields:    Translation:Humans
    25. Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E, AsthmaNet Investigators. Reply. J Allergy Clin Immunol. 2019 09; 144(3):873-874. PMID: 31300279.
      Citations:    Fields:    
    26. Sharma A, Laxman B, Naureckas ET, Hogarth DK, Sperling AI, Solway J, Ober C, Gilbert JA, White SR. Associations between fungal and bacterial microbiota of airways and asthma endotypes. J Allergy Clin Immunol. 2019 11; 144(5):1214-1227.e7. PMID: 31279011; PMCID: PMC6842419.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    27. White SR, Laxman B, Naureckas ET, Hogarth DK, Solway J, Sperling AI, Ober C. Evidence for an IL-6-high asthma phenotype in asthmatic patients of African ancestry. J Allergy Clin Immunol. 2019 07; 144(1):304-306.e4. PMID: 31029772; PMCID: PMC6612296.
      Citations: 8     Fields:    Translation:Humans
    28. Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E, AsthmaNet Investigators. Loss of bronchoprotection with ICS plus LABA treatment, ß-receptor dynamics, and the effect of alendronate. J Allergy Clin Immunol. 2019 08; 144(2):416-425.e7. PMID: 30872116; PMCID: PMC6950766.
      Citations: 1     Fields:    Translation:Humans
    29. Shigemura M, Lecuona E, Homma T, Gonzalez-Gonzalez FJ, Welch LC, Amarelle L, Kim SJ, Kaminski N, Budinger GRS, Solway J, Sznajder JI, Angulo M, Rodríguez DA. Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling. Sci Transl Med. 2018 09 05; 10(457). PMID: 30185650; PMCID: PMC6889079.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    30. Gray CL, Lobdell DT, Rappazzo KM, Jian Y, Jagai JS, Messer LC, Patel AP, DeFlorio-Barker SA, Lyttle C, Solway J, Rzhetsky A. Associations between environmental quality and adult asthma prevalence in medical claims data. Environ Res. 2018 10; 166:529-536. PMID: 29957506; PMCID: PMC6110955.
      Citations: 10     Fields:    Translation:Humans
    31. Chua MD, Hipolito KJ, Singerr OB, Solway J, Guttman JA. SM22 is required for the maintenance of actin-rich structures generated during bacterial infections. Exp Cell Res. 2018 08 01; 369(1):139-146. PMID: 29778753.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    32. Krishack PA, Wang K, Rzhetsky A, Solway J, Sperling AI, Verhoef PA. Preexisting Type 2 Immune Activation Protects against the Development of Sepsis. Am J Respir Cell Mol Biol. 2017 11; 57(5):628-630. PMID: 29090959; PMCID: PMC5705910.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    33. White SR, Nicodemus-Johnson J, Laxman B, Denner DR, Naureckas ET, Hogarth DK, Stern R, Minc A, Solway J, Sperling A, Ober C. Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma. J Allergy Clin Immunol. 2017 09; 140(3):857-860. PMID: 28363527; PMCID: PMC5591772.
      Citations: 9     Fields:    Translation:HumansCells
    34. Nicodemus-Johnson J, Myers RA, Sakabe NJ, Sobreira DR, Hogarth DK, Naureckas ET, Sperling AI, Solway J, White SR, Nobrega MA, Nicolae DL, Gilad Y, Ober C. DNA methylation in lung cells is associated with asthma endotypes and genetic risk. JCI Insight. 2016 12 08; 1(20):e90151. PMID: 27942592; PMCID: PMC5139904.
      Citations: 76     Fields:    Translation:HumansCells
    35. An SS, Mitzner W, Tang WY, Ahn K, Yoon AR, Huang J, Kilic O, Yong HM, Fahey JW, Kumar S, Biswal S, Holgate ST, Panettieri RA, Solway J, Liggett SB. An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma. J Allergy Clin Immunol. 2016 07; 138(1):294-297.e4. PMID: 26936804; PMCID: PMC4931984.
      Citations: 36     Fields:    Translation:HumansCells
    36. Nicodemus-Johnson J, Naughton KA, Sudi J, Hogarth K, Naurekas ET, Nicolae DL, Sperling AI, Solway J, White SR, Ober C. Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways. Am J Respir Crit Care Med. 2016 Feb 15; 193(4):376-85. PMID: 26474238; PMCID: PMC4803084.
      Citations: 54     Fields:    Translation:HumansCells
    37. Levy BD, Noel PJ, Freemer MM, Cloutier MM, Georas SN, Jarjour NN, Ober C, Woodruff PG, Barnes KC, Bender BG, Camargo CA, Chupp GL, Denlinger LC, Fahy JV, Fitzpatrick AM, Fuhlbrigge A, Gaston BM, Hartert TV, Kolls JK, Lynch SV, Moore WC, Morgan WJ, Nadeau KC, Ownby DR, Solway J, Szefler SJ, Wenzel SE, Wright RJ, Smith RA, Erzurum SC. Future Research Directions in Asthma. An NHLBI Working Group Report. Am J Respir Crit Care Med. 2015 Dec 01; 192(11):1366-72. PMID: 26305520; PMCID: PMC4731702.
      Citations: 37     Fields:    Translation:Humans
    38. Denner DR, Sangwan N, Becker JB, Hogarth DK, Oldham J, Castillo J, Sperling AI, Solway J, Naureckas ET, Gilbert JA, White SR. Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways. J Allergy Clin Immunol. 2016 05; 137(5):1398-1405.e3. PMID: 26627545; PMCID: PMC4860110.
      Citations: 91     Fields:    Translation:HumansCells
    39. Wang J, Chen L, Chen B, Meliton A, Liu SQ, Shi Y, Liu T, Deb DK, Solway J, Li YC. Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis. Sci Rep. 2015 Oct 23; 5:15561. PMID: 26494430; PMCID: PMC4616037.
      Citations: 32     Fields:    Translation:Animals
    40. Park CY, Zhou EH, Tambe D, Chen B, Lavoie T, Dowell M, Simeonov A, Maloney DJ, Marinkovic A, Tschumperlin DJ, Burger S, Frykenberg M, Butler JP, Stamer WD, Johnson M, Solway J, Fredberg JJ, Krishnan R. High-throughput screening for modulators of cellular contractile force. Integr Biol (Camb). 2015 Oct; 7(10):1318-24. PMID: 25953078; PMCID: PMC4657543.
      Citations: 35     Fields:    Translation:HumansCells
    41. Comer BS, Camoretti-Mercado B, Kogut PC, Halayko AJ, Solway J, Gerthoffer WT. Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells. Am J Respir Cell Mol Biol. 2015 Apr; 52(4):438-47. PMID: 25180620; PMCID: PMC4491121.
      Citations: 23     Fields:    Translation:HumansCells
    42. Wu K, Gamazon ER, Im HK, Geeleher P, White SR, Solway J, Clemmer GL, Weiss ST, Tantisira KG, Cox NJ, Ratain MJ, Huang RS. Genome-wide interrogation of longitudinal FEV1 in children with asthma. Am J Respir Crit Care Med. 2014 Sep 15; 190(6):619-27. PMID: 25221879; PMCID: PMC4214107.
      Citations: 8     Fields:    Translation:HumansCells
    43. Comer BS, Camoretti-Mercado B, Kogut PC, Halayko AJ, Solway J, Gerthoffer WT. MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2014 Nov 01; 307(9):L727-34. PMID: 25217662; PMCID: PMC4217003.
      Citations: 64     Fields:    Translation:HumansCells
    44. Sharma S, Zhou X, Thibault DM, Himes BE, Liu A, Szefler SJ, Strunk R, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Barraza-Villareal A, Lemanske RF, Solway J, Krishnan J, White SR, Cheadle C, Berger AE, Fan J, Boorgula MP, Nicolae D, Gilliland F, Barnes K, London SJ, Martinez F, Ober C, Carey VJ, Weiss ST, Raby BA, Avila L, Soto-Quiros M, Celedón JC. A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol. 2014 Nov; 134(5):1153-62. PMID: 24934276; PMCID: PMC4253878.
      Citations: 30     Fields:    Translation:HumansCells
    45. Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, Avila P, Bacharier LB, Bleecker E, Boushey HA, Chmiel J, Fitzpatrick AM, Gentile D, Hundal M, Israel E, Kraft M, Krishnan JA, LaForce C, Lazarus SC, Lemanske R, Lugogo N, Martin RJ, Mauger DT, Naureckas E, Peters SP, Phipatanakul W, Que LG, Sheshadri A, Smith L, Solway J, Sullivan-Vedder L, Sumino K, Wechsler ME, Wenzel S, White SR, Sutherland ER, National Heart, Lung, and Blood Institute’s AsthmaNet. Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial. JAMA. 2014 May; 311(20):2083-91. PMID: 24838406; PMCID: PMC4217655.
      Citations: 113     Fields:    Translation:Humans
    46. Rosner SR, Ram-Mohan S, Paez-Cortez JR, Lavoie TL, Dowell ML, Yuan L, Ai X, Fine A, Aird WC, Solway J, Fredberg JJ, Krishnan R. Airway contractility in the precision-cut lung slice after cryopreservation. Am J Respir Cell Mol Biol. 2014 May; 50(5):876-81. PMID: 24313705; PMCID: PMC4068941.
      Citations: 30     Fields:    Translation:AnimalsCells
    47. Mambetsariev I, Tian Y, Wu T, Lavoie T, Solway J, Birukov KG, Birukova AA. Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation. PLoS One. 2014; 9(4):e92670. PMID: 24739883; PMCID: PMC3989185.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    48. Chen B, Moore TV, Li Z, Sperling AI, Zhang C, Andrade J, Rodriguez A, Bahroos N, Huang Y, Morrisey EE, Gruber PJ, Solway J. Gata5 deficiency causes airway constrictor hyperresponsiveness in mice. Am J Respir Cell Mol Biol. 2014 Apr; 50(4):787-95. PMID: 24199649; PMCID: PMC4068924.
      Citations: 9     Fields:    Translation:AnimalsCells
    49. Qiao G, Ying H, Zhao Y, Liang Y, Guo H, Shen H, Li Z, Solway J, Tao E, Penninger JM, Langdon WY, Zhang J, Chiang YJ, Lipkowitz S. E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammation. Cell Rep. 2014 Feb 27; 6(4):709-23. PMID: 24508458; PMCID: PMC3969736.
      Citations: 32     Fields:    Translation:AnimalsCells
    50. Dowell ML, Lavoie TL, Solway J, Krishnan R. Airway smooth muscle: a potential target for asthma therapy. Curr Opin Pulm Med. 2014 Jan; 20(1):66-72. PMID: 24247041.
      Citations: 9     Fields:    Translation:HumansCells
    51. Gerthoffer WT, Solway J, Camoretti-Mercado B. Emerging targets for novel therapy of asthma. Curr Opin Pharmacol. 2013 Jun; 13(3):324-30. PMID: 23639507; PMCID: PMC3686997.
      Citations: 28     Fields:    Translation:HumansAnimals
    52. Reis SE, Patterson PD, Fitzgerald GA, Ford D, Sherwin RS, Solway J, Evanoff BA. The sharing partnership for innovative research in translation (SPIRiT) consortium: a model for collaboration across CTSA sites. Clin Transl Sci. 2013 Apr; 6(2):85-7. PMID: 23601335; PMCID: PMC3633092.
      Citations: 3     Fields:    Translation:Humans
    53. Nicodemus-Johnson J, Laxman B, Stern RK, Sudi J, Tierney CN, Norwick L, Hogarth DK, McConville JF, Naureckas ET, Sperling AI, Solway J, Krishnan JA, Nicolae DL, White SR, Ober C. Maternal asthma and microRNA regulation of soluble HLA-G in the airway. J Allergy Clin Immunol. 2013 Jun; 131(6):1496-503. PMID: 23534973; PMCID: PMC3779062.
      Citations: 26     Fields:    Translation:HumansPHPublic Health
    54. Doeing DC, Solway J. Airway smooth muscle in the pathophysiology and treatment of asthma. J Appl Physiol (1985). 2013 Apr; 114(7):834-43. PMID: 23305987; PMCID: PMC3633438.
      Citations: 63     Fields:    Translation:Humans
    55. Chen B, Hsu R, Li Z, Kogut PC, Du Q, Rouser K, Camoretti-Mercado B, Solway J. Upstream stimulatory factor 1 activates GATA5 expression through an E-box motif. Biochem J. 2012 Aug 15; 446(1):89-98. PMID: 22625849; PMCID: PMC3677829.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    56. Jude JA, Dileepan M, Subramanian S, Solway J, Panettieri RA, Walseth TF, Kannan MS. miR-140-3p regulation of TNF-a-induced CD38 expression in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2012 Sep; 303(5):L460-8. PMID: 22773691; PMCID: PMC3468424.
      Citations: 58     Fields:    Translation:HumansCells
    57. Lavoie TL, Krishnan R, Siegel HR, Maston ED, Fredberg JJ, Solway J, Dowell ML. Dilatation of the constricted human airway by tidal expansion of lung parenchyma. Am J Respir Crit Care Med. 2012 Aug 01; 186(3):225-32. PMID: 22679010; PMCID: PMC3423451.
      Citations: 48     Fields:    Translation:Humans
    58. Center DM, Schwartz DA, Solway J, Gail D, Laposky AD, Lin QS, Gan W. Genomic medicine and lung diseases. Am J Respir Crit Care Med. 2012 Aug 01; 186(3):280-5. PMID: 22652029; PMCID: PMC3423454.
      Citations: 4     Fields:    Translation:Humans
    59. CTSA Principal Investigators, Shamoon H, Center D, Davis P, Tuchman M, Ginsberg H, Califf R, Stephens D, Mellman T, Verbalis J, Nadler L, Shekhar A, Ford D, Rizza R, Shaker R, Brady K, Murphy B, Cronstein B, Hochman J, Greenland P, Orwoll E, Sinoway L, Greenberg H, Jackson R, Coller B, Topol E, Guay-Woodford L, Runge M, Clark R, McClain D, Selker H, Lowery C, Dubinett S, Berglund L, Cooper D, Firestein G, Johnston SC, Solway J, Heubi J, Sokol R, Nelson D, Tobacman L, Rosenthal G, Aaronson L, Barohn R, Kern P, Sullivan J, Shanley T, Blazar B, Larson R, FitzGerald G, Reis S, Pearson T, Buchanan T, McPherson D, Brasier A, Toto R, Disis M, Drezner M, Bernard G, Clore J, Evanoff B, Imperato-McGinley J, Sherwin R, Pulley J. Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS). Clin Transl Sci. 2012 Apr; 5(2):121-9. PMID: 22507116; PMCID: PMC3335735.
      Citations: 13     Fields:    Translation:HumansAnimals
    60. Ferreira CM, Chen JL, Li J, Shimomura K, Yang X, Lussier YA, Pinto LH, Solway J. Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice. PLoS One. 2012; 7(1):e29579. PMID: 22253740; PMCID: PMC3254621.
      Citations: 5     Fields:    Translation:AnimalsCells
    61. Brueggemann LI, Kakad PP, Love RB, Solway J, Dowell ML, Cribbs LL, Byron KL. Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy. Am J Physiol Lung Cell Mol Physiol. 2012 Jan 01; 302(1):L120-32. PMID: 21964407; PMCID: PMC3349372.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    62. Ma L, Brown M, Kogut P, Serban K, Li X, McConville J, Chen B, Bentley JK, Hershenson MB, Dulin N, Solway J, Camoretti-Mercado B. Akt activation induces hypertrophy without contractile phenotypic maturation in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2011 May; 300(5):L701-9. PMID: 21378028; PMCID: PMC3094029.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    63. Seow CY, Solway J. Mechanical and structural plasticity. Compr Physiol. 2011 Jan; 1(1):283-93. PMID: 23737173.
      Citations: 5     Fields:    Translation:HumansCells
    64. McConville JF, Fernandes DJ, Churchill J, Dewundara S, Kogut P, Shah S, Fuchs G, Kedainis D, Bellam SK, Patel NM, McCauley J, Dulin NO, Gupta MP, Adam S, Yoneda Y, Camoretti-Mercado B, Solway J. Nuclear import of serum response factor in airway smooth muscle. Am J Respir Cell Mol Biol. 2011 Sep; 45(3):453-8. PMID: 21131446; PMCID: PMC3175573.
      Citations: 2     Fields:    Translation:HumansCells
    65. Jude JA, Solway J, Panettieri RA, Walseth TF, Kannan MS. Differential induction of CD38 expression by TNF-{alpha} in asthmatic airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2010 Dec; 299(6):L879-90. PMID: 20693316; PMCID: PMC3006261.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    66. Dowell ML, Lavoie TL, Lakser OJ, Dulin NO, Fredberg JJ, Gerthoffer WT, Seow CY, Mitchell RW, Solway J. MEK modulates force-fluctuation-induced relengthening of canine tracheal smooth muscle. Eur Respir J. 2010 Sep; 36(3):630-7. PMID: 20110395; PMCID: PMC3918254.
      Citations: 8     Fields:    Translation:AnimalsCells
    67. Nesterovitch AB, Hogarth KD, Adarichev VA, Vinokour EI, Schwartz DE, Solway J, Danilov SM. Angiotensin I-converting enzyme mutation (Trp1197Stop) causes a dramatic increase in blood ACE. PLoS One. 2009 Dec 14; 4(12):e8282. PMID: 20011602; PMCID: PMC2788243.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    68. Solway J, Rehman B, Ross LF. The University of Chicago Institute for Translational Medicine. Clin Transl Sci. 2009 Dec; 2(6):394-7. PMID: 20443930; PMCID: PMC4263030.
      Citations:    Fields:    
    69. Chen B, Yates E, Huang Y, Kogut P, Ma L, Turner JR, Tao Y, Camoretti-Mercado B, Lang D, Svensson EC, Garcia JG, Gruber PJ, Morrisey EE, Solway J. Alternative promoter and GATA5 transcripts in mouse. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1214-22. PMID: 19779014; PMCID: PMC2850090.
      Citations: 7     Fields:    Translation:AnimalsCells
    70. Deng H, Hershenson MB, Lei J, Bitar KN, Fingar DC, Solway J, Bentley JK. p70 Ribosomal S6 kinase is required for airway smooth muscle cell size enlargement but not increased contractile protein expression. Am J Respir Cell Mol Biol. 2010 Jun; 42(6):744-52. PMID: 19648476; PMCID: PMC2891500.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    71. He D, Su Y, Usatyuk PV, Spannhake EW, Kogut P, Solway J, Natarajan V, Zhao Y. Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrier disruption and lung injury. J Biol Chem. 2009 Sep 04; 284(36):24123-32. PMID: 19586906; PMCID: PMC2782006.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    72. Lavoie TL, Dowell ML, Lakser OJ, Gerthoffer WT, Fredberg JJ, Seow CY, Mitchell RW, Solway J. Disrupting actin-myosin-actin connectivity in airway smooth muscle as a treatment for asthma? Proc Am Thorac Soc. 2009 May 01; 6(3):295-300. PMID: 19387033; PMCID: PMC2677405.
      Citations: 20     Fields:    Translation:HumansCells
    73. Laviolette M, Bergeron C, Zitouni N, Kogut P, Solway J, Kachmar L, Hamid Q, Lauzon AM, Léguillette R. Myosin, transgelin, and myosin light chain kinase: expression and function in asthma. Am J Respir Crit Care Med. 2009 Feb 01; 179(3):194-204. PMID: 19011151; PMCID: PMC2633053.
      Citations: 51     Fields:    Translation:HumansAnimals
    74. Lakser OJ, Dowell ML, Hoyte FL, Chen B, Lavoie TL, Ferreira C, Pinto LH, Dulin NO, Kogut P, Churchill J, Mitchell RW, Solway J. Steroids augment relengthening of contracted airway smooth muscle: potential additional mechanism of benefit in asthma. Eur Respir J. 2008 Nov; 32(5):1224-30. PMID: 18768574; PMCID: PMC2582388.
      Citations: 14     Fields:    Translation:AnimalsCells
    75. He D, Natarajan V, Stern R, Gorshkova IA, Solway J, Spannhake EW, Zhao Y. Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E(2) release via C/EBPbeta in human bronchial epithelial cells. Biochem J. 2008 May 15; 412(1):153-62. PMID: 18294142; PMCID: PMC2659593.
      Citations: 28     Fields:    Translation:HumansCells
    76. Mitchell RW, Dowell ML, Solway J, Lakser OJ. Force fluctuation-induced relengthening of acetylcholine-contracted airway smooth muscle. Proc Am Thorac Soc. 2008 Jan 01; 5(1):68-72. PMID: 18094087; PMCID: PMC2645304.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    77. Hershenson MB, Brown M, Camoretti-Mercado B, Solway J. Airway smooth muscle in asthma. Annu Rev Pathol. 2008; 3:523-55. PMID: 18039134.
      Citations: 40     Fields:    Translation:HumansAnimals
    78. Pinto LH, Eaton E, Chen B, Fleisher J, Shuster D, McCauley J, Kedainis D, Siepka SM, Shimomura K, Song EJ, Husain A, Lakser OJ, Mitchell RW, Dowell ML, Brown M, Camoretti-Mercado B, Naclerio R, Sperling AI, Levin SI, Turek FW, Solway J. Gene-environment interactions in a mutant mouse kindred with native airway constrictor hyperresponsiveness. Mamm Genome. 2008 Jan; 19(1):2-14. PMID: 18167028.
      Citations: 2     Fields:    Translation:Animals
    79. Tan Z, Randall G, Fan J, Camoretti-Mercado B, Brockman-Schneider R, Pan L, Solway J, Gern JE, Lemanske RF, Nicolae D, Ober C. Allele-specific targeting of microRNAs to HLA-G and risk of asthma. Am J Hum Genet. 2007 Oct; 81(4):829-34. PMID: 17847008; PMCID: PMC2227932.
      Citations: 175     Fields:    Translation:HumansCells
    80. Bandukwala HS, Clay BS, Tong J, Mody PD, Cannon JL, Shilling RA, Verbeek JS, Weinstock JV, Solway J, Sperling AI. Signaling through Fc gamma RIII is required for optimal T helper type (Th)2 responses and Th2-mediated airway inflammation. J Exp Med. 2007 Aug 06; 204(8):1875-89. PMID: 17664287; PMCID: PMC2118666.
      Citations: 38     Fields:    Translation:AnimalsCells
    81. An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PS, Smith PG, Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L, Paré PD. Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma. Eur Respir J. 2007 May; 29(5):834-60. PMID: 17470619; PMCID: PMC2527453.
      Citations: 144     Fields:    Translation:Humans
    82. Solway J, Irvin CG. Airway smooth muscle as a target for asthma therapy. N Engl J Med. 2007 Mar 29; 356(13):1367-9. PMID: 17392308.
      Citations: 11     Fields:    Translation:Humans
    83. Sun Y, Blink SE, Liu W, Lee Y, Chen B, Solway J, Weinstock J, Chen L, Fu YX. Inhibition of Th2-mediated allergic airway inflammatory disease by CD137 costimulation. J Immunol. 2006 Jul 15; 177(2):814-21. PMID: 16818735.
      Citations: 14     Fields:    Translation:AnimalsCells
    84. Nair RR, Solway J, Boyd DD. Expression cloning identifies transgelin (SM22) as a novel repressor of 92-kDa type IV collagenase (MMP-9) expression. J Biol Chem. 2006 Sep 08; 281(36):26424-36. PMID: 16835221.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    85. Camoretti-Mercado B, Fernandes DJ, Dewundara S, Churchill J, Ma L, Kogut PC, McConville JF, Parmacek MS, Solway J. Inhibition of transforming growth factor beta-enhanced serum response factor-dependent transcription by SMAD7. J Biol Chem. 2006 Jul 21; 281(29):20383-92. PMID: 16690609.
      Citations: 20     Fields:    Translation:AnimalsCells
    86. Tong J, Bandulwala HS, Clay BS, Anders RA, Shilling RA, Balachandran DD, Chen B, Weinstock JV, Solway J, Hamann KJ, Sperling AI. Fas-positive T cells regulate the resolution of airway inflammation in a murine model of asthma. J Exp Med. 2006 May 15; 203(5):1173-84. PMID: 16618792; PMCID: PMC2121201.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    87. Chen B, Liu G, Shardonofsky F, Dowell M, Lakser O, Mitchell RW, Fredberg JJ, Pinto LH, Solway J. Tidal breathing pattern differentially antagonizes bronchoconstriction in C57BL/6J vs. A/J mice. J Appl Physiol (1985). 2006 Jul; 101(1):249-55. PMID: 16484363.
      Citations: 9     Fields:    Translation:AnimalsCells
    88. Kim IM, Zhou Y, Ramakrishna S, Hughes DE, Solway J, Costa RH, Kalinichenko VV. Functional characterization of evolutionarily conserved DNA regions in forkhead box f1 gene locus. J Biol Chem. 2005 Nov 11; 280(45):37908-16. PMID: 16144835.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    89. Camoretti-Mercado B, Dulin NO, Solway J. SRF function in vascular smooth muscle: when less is more? Circ Res. 2005 Sep 02; 97(5):409-10. PMID: 16141114.
      Citations: 1     Fields:    Translation:Animals
    90. Weiss LA, Lester LA, Gern JE, Wolf RL, Parry R, Lemanske RF, Solway J, Ober C. Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations. Am J Respir Crit Care Med. 2005 Jul 01; 172(1):67-73. PMID: 15817799; PMCID: PMC2718448.
      Citations: 19     Fields:    Translation:HumansCells
    91. Camoretti-Mercado B, Solway J. Transforming growth factor-beta1 and disorders of the lung. Cell Biochem Biophys. 2005; 43(1):131-48. PMID: 16043890.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    92. Nicolae D, Cox NJ, Lester LA, Schneider D, Tan Z, Billstrand C, Kuldanek S, Donfack J, Kogut P, Patel NM, Goodenbour J, Howard T, Wolf R, Koppelman GH, White SR, Parry R, Postma DS, Meyers D, Bleecker ER, Hunt JS, Solway J, Ober C. Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet. 2005 Feb; 76(2):349-57. PMID: 15611928; PMCID: PMC1196380.
      Citations: 80     Fields:    Translation:HumansCells
    93. Bai TR, Bates JH, Brusasco V, Camoretti-Mercado B, Chitano P, Deng LH, Dowell M, Fabry B, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gunst SJ, Hai CM, Halayko AJ, Hirst SJ, James AL, Janssen LJ, Jones KA, King GG, Lakser OJ, Lambert RK, Lauzon AM, Lutchen KR, Maksym GN, Meiss RA, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Schellenberg RR, Seow CY, Sieck GC, Smith PG, Smolensky AV, Solway J, Stephens NL, Stewart AG, Tang DD, Wang L, Paré PD. On the terminology for describing the length-force relationship and its changes in airway smooth muscle. J Appl Physiol (1985). 2004 Dec; 97(6):2029-34. PMID: 15531570.
      Citations: 29     Fields:    Translation:HumansAnimals
    94. Fernandes DJ, McConville JF, Stewart AG, Kalinichenko V, Solway J. Can we differentiate between airway and vascular smooth muscle? Clin Exp Pharmacol Physiol. 2004 Nov; 31(11):805-10. PMID: 15566398.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    95. Dowell ML, Lakser OJ, Gerthoffer WT, Fredberg JJ, Stelmack GL, Halayko AJ, Solway J, Mitchell RW. Latrunculin B increases force fluctuation-induced relengthening of ACh-contracted, isotonically shortened canine tracheal smooth muscle. J Appl Physiol (1985). 2005 Feb; 98(2):489-97. PMID: 15465883.
      Citations: 21     Fields:    Translation:AnimalsCells
    96. Bates J, Irvin C, Brusasco V, Drazen J, Fredberg J, Loring S, Eidelman D, Ludwig M, Macklem P, Martin J, Milic-Emili J, Hantos Z, Hyatt R, Lai-Fook S, Leff A, Solway J, Lutchen K, Suki B, Mitzner W, Pride N, Sly P, Paré P. The use and misuse of Penh in animal models of lung disease. Am J Respir Cell Mol Biol. 2004 Sep; 31(3):373-4. PMID: 15317683.
      Citations: 72     Fields:    Translation:Animals
    97. Kotlikoff MI, Kannan MS, Solway J, Deng KY, Deshpande DA, Dowell M, Feldman M, Green KS, Ji G, Johnston R, Lakser O, Lee J, Lund FE, Milla C, Mitchell RW, Nakai J, Rishniw M, Walseth TF, White TA, Wilson J, Xin HB, Woodruff PG. Methodologic advancements in the study of airway smooth muscle. J Allergy Clin Immunol. 2004 Aug; 114(2 Suppl):S18-31. PMID: 15309016.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    98. Pinto JM, Assanasen P, Baroody FM, Naureckas E, Solway J, Naclerio RM. Treatment of nasal inflammation decreases the ability of subjects with asthma to condition inspired air. Am J Respir Crit Care Med. 2004 Oct 15; 170(8):863-9. PMID: 15172894.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    99. Halayko AJ, Kartha S, Stelmack GL, McConville J, Tam J, Camoretti-Mercado B, Forsythe SM, Hershenson MB, Solway J. Phophatidylinositol-3 kinase/mammalian target of rapamycin/p70S6K regulates contractile protein accumulation in airway myocyte differentiation. Am J Respir Cell Mol Biol. 2004 Sep; 31(3):266-75. PMID: 15105162.
      Citations: 33     Fields:    Translation:AnimalsCells
    100. Robin B, Kim YJ, Huth J, Klocksieben J, Torres M, Tepper RS, Castile RG, Solway J, Hershenson MB, Goldstein-Filbrun A. Pulmonary function in bronchopulmonary dysplasia. Pediatr Pulmonol. 2004 Mar; 37(3):236-42. PMID: 14966817.
      Citations: 48     Fields:    Translation:HumansCTClinical Trials
    101. Zhou L, Li J, Goldsmith AM, Newcomb DC, Giannola DM, Vosk RG, Eves EM, Rosner MR, Solway J, Hershenson MB. Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma. Am J Respir Crit Care Med. 2004 Mar 15; 169(6):703-11. PMID: 14693670.
      Citations: 13     Fields:    Translation:HumansCells
    102. Kang HS, Blink SE, Chin RK, Lee Y, Kim O, Weinstock J, Waldschmidt T, Conrad D, Chen B, Solway J, Sperling AI, Fu YX. Lymphotoxin is required for maintaining physiological levels of serum IgE that minimizes Th1-mediated airway inflammation. J Exp Med. 2003 Dec 01; 198(11):1643-52. PMID: 14638845; PMCID: PMC2194142.
      Citations: 13     Fields:    Translation:AnimalsCells
    103. Funkhouser AW, Kang JA, Tan A, Li J, Zhou L, Abe MK, Solway J, Hershenson MB. Rhinovirus 16 3C protease induces interleukin-8 and granulocyte-macrophage colony-stimulating factor expression in human bronchial epithelial cells. Pediatr Res. 2004 Jan; 55(1):13-8. PMID: 14605258.
      Citations: 11     Fields:    Translation:HumansCells
    104. Blumenthal MN, Langefeld CD, Beaty TH, Bleecker ER, Ober C, Lester L, Lange E, Barnes KC, Wolf R, King RA, Solway J, Oetting W, Meyers DA, Rich SS. A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma. Hum Genet. 2004 Jan; 114(2):157-64. PMID: 14586638.
      Citations: 21     Fields:    Translation:Humans
    105. Camoretti-Mercado B, Dulin NO, Solway J. Serum response factor function and dysfunction in smooth muscle. Respir Physiol Neurobiol. 2003 Sep 16; 137(2-3):223-35. PMID: 14516728.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    106. Fernandes DJ, Mitchell RW, Lakser O, Dowell M, Stewart AG, Solway J. Do inflammatory mediators influence the contribution of airway smooth muscle contraction to airway hyperresponsiveness in asthma? J Appl Physiol (1985). 2003 Aug; 95(2):844-53. PMID: 12851423.
      Citations: 9     Fields:    Translation:HumansAnimals
    107. Davis A, Hogarth K, Fernandes D, Solway J, Niu J, Kolenko V, Browning D, Miano JM, Orlov SN, Dulin NO. Functional significance of protein kinase A activation by endothelin-1 and ATP: negative regulation of SRF-dependent gene expression by PKA. Cell Signal. 2003 Jun; 15(6):597-604. PMID: 12681447.
      Citations: 17     Fields:    Translation:AnimalsCells
    108. Assanasen P, Baroody FM, Haney L, deTineo M, Naureckas E, Solway J, Naclerio RM. Elevation of the nasal mucosal surface temperature after warming of the feet occurs via a neural reflex. Acta Otolaryngol. 2003 Jun; 123(5):627-36. PMID: 12875586.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    109. Solway J, Bellam S, Dowell M, Camoretti-Mercado B, Dulin N, Fernandes D, Halayko A, Kocieniewski P, Kogut P, Lakser O, Liu HW, McCauley J, McConville J, Mitchell R. Actin dynamics: a potential integrator of smooth muscle (Dys-)function and contractile apparatus gene expression in asthma. Parker B. Francis lecture. Chest. 2003 Mar; 123(3 Suppl):392S-8S. PMID: 12629000.
      Citations: 5     Fields:    Translation:Humans
    110. Donfack J, Kogut P, Forsythe S, Solway J, Ober C. Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy. J Allergy Clin Immunol. 2003 Mar; 111(3):527-32. PMID: 12642833.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    111. Dulin NO, Fernandes DJ, Dowell M, Bellam S, McConville J, Lakser O, Mitchell R, Camoretti-Mercado B, Kogut P, Solway J. What evidence implicates airway smooth muscle in the cause of BHR? Clin Rev Allergy Immunol. 2003 Feb; 24(1):73-84. PMID: 12644719.
      Citations: 12     Fields:    Translation:HumansAnimals
    112. Liu HW, Halayko AJ, Fernandes DJ, Harmon GS, McCauley JA, Kocieniewski P, McConville J, Fu Y, Forsythe SM, Kogut P, Bellam S, Dowell M, Churchill J, Lesso H, Kassiri K, Mitchell RW, Hershenson MB, Camoretti-Mercado B, Solway J. The RhoA/Rho kinase pathway regulates nuclear localization of serum response factor. Am J Respir Cell Mol Biol. 2003 Jul; 29(1):39-47. PMID: 12600823.
      Citations: 54     Fields:    Translation:AnimalsCells
    113. Forsythe SM, Kogut PC, McConville JF, Fu Y, McCauley JA, Halayko AJ, Liu HW, Kao A, Fernandes DJ, Bellam S, Fuchs E, Sinha S, Bell GI, Camoretti-Mercado B, Solway J. Structure and transcription of the human m3 muscarinic receptor gene. Am J Respir Cell Mol Biol. 2002 Mar; 26(3):298-305. PMID: 11867338.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    114. Assanasen P, Baroody FM, Naureckas E, Solway J, Naclerio RM. Supine position decreases the ability of the nose to warm and humidify air. J Appl Physiol (1985). 2001 Dec; 91(6):2459-65. PMID: 11717205.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    115. Assanasen P, Baroody FM, Naureckas E, Solway J, Naclerio RM. The nasal passage of subjects with asthma has a decreased ability to warm and humidify inspired air. Am J Respir Crit Care Med. 2001 Nov 01; 164(9):1640-6. PMID: 11719303.
      Citations: 4     Fields:    Translation:HumansCells
    116. Naureckas ET, Solway J. Clinical practice. Mild asthma. N Engl J Med. 2001 Oct 25; 345(17):1257-62. PMID: 11680447.
      Citations:    Fields:    Translation:Humans
    117. Lester LA, Rich SS, Blumenthal MN, Togias A, Murphy S, Malveaux F, Miller ME, Dunston GM, Solway J, Wolf RL, Samet JM, Marsh DG, Meyers DA, Ober C, Bleecker ER, Collaborative Study on the Genetics of Asthma. Ethnic differences in asthma and associated phenotypes: collaborative study on the genetics of asthma. J Allergy Clin Immunol. 2001 Sep; 108(3):357-62. PMID: 11544453.
      Citations: 49     Fields:    Translation:Humans
    118. Xu J, Meyers DA, Ober C, Blumenthal MN, Mellen B, Barnes KC, King RA, Lester LA, Howard TD, Solway J, Langefeld CD, Beaty TH, Rich SS, Bleecker ER, Cox NJ, Collaborative Study on the Genetics of Asthma. Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma. Am J Hum Genet. 2001 Jun; 68(6):1437-46. PMID: 11349227; PMCID: PMC1226130.
      Citations: 52     Fields:    Translation:HumansCells
    119. Mathias RA, Freidhoff LR, Blumenthal MN, Meyers DA, Lester L, King R, Xu JF, Solway J, Barnes KC, Pierce J, Stine OC, Togias A, Oetting W, Marshik PL, Hetmanski JB, Huang SK, Ehrlich E, Dunston GM, Malveaux F, Banks-Schlegel S, Cox NJ, Bleecker E, Ober C, Beaty TH, Rich SS, CSGA (Collaborative Study of the Genetics of Asthma). Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families. Genet Epidemiol. 2001 Apr; 20(3):340-55. PMID: 11255243.
      Citations: 24     Fields:    Translation:Humans
    120. Halayko AJ, Solway J. Molecular mechanisms of phenotypic plasticity in smooth muscle cells. J Appl Physiol (1985). 2001 Jan; 90(1):358-68. PMID: 11133929.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    121. Assanasen P, Baroody FM, Abbott DJ, Naureckas E, Solway J, Naclerio RM. Natural and induced allergic responses increase the ability of the nose to warm and humidify air. J Allergy Clin Immunol. 2000 Dec; 106(6):1045-52. PMID: 11112885.
      Citations: 3     Fields:    Translation:Humans
    122. Fu Y, Liu HW, Forsythe SM, Kogut P, McConville JF, Halayko AJ, Camoretti-Mercado B, Solway J. Mutagenesis analysis of human SM22: characterization of actin binding. J Appl Physiol (1985). 2000 Nov; 89(5):1985-90. PMID: 11053353.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    123. Camoretti-Mercado B, Liu HW, Halayko AJ, Forsythe SM, Kyle JW, Li B, Fu Y, McConville J, Kogut P, Vieira JE, Patel NM, Hershenson MB, Fuchs E, Sinha S, Miano JM, Parmacek MS, Burkhardt JK, Solway J. Physiological control of smooth muscle-specific gene expression through regulated nuclear translocation of serum response factor. J Biol Chem. 2000 Sep 29; 275(39):30387-93. PMID: 10866994.
      Citations: 34     Fields:    Translation:AnimalsCells
    124. Assanasen P, Baroody FM, Rouadi P, Naureckas E, Solway J, Naclerio RM. Ipratropium bromide increases the ability of the nose to warm and humidify air. Am J Respir Crit Care Med. 2000 Sep; 162(3 Pt 1):1031-7. PMID: 10988126.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    125. Summerhill E, Leavitt SA, Gidley H, Parry R, Solway J, Ober C. beta(2)-adrenergic receptor Arg16/Arg16 genotype is associated with reduced lung function, but not with asthma, in the Hutterites. Am J Respir Crit Care Med. 2000 Aug; 162(2 Pt 1):599-602. PMID: 10934093.
      Citations: 21     Fields:    Translation:HumansCells
    126. Donfack J, Tsalenko A, Hoki DM, Parry R, Solway J, Lester LA, Ober C. HLA-DRB1*01 alleles are associated with sensitization to cockroach allergens. J Allergy Clin Immunol. 2000 May; 105(5):960-6. PMID: 10808177.
      Citations: 11     Fields:    Translation:HumansAnimalsPHPublic Health
    127. Mitchell RW, Halayko AJ, Kahraman S, Solway J, Wylam ME. Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes. Am J Physiol Lung Cell Mol Physiol. 2000 May; 278(5):L1091-100. PMID: 10781442.
      Citations: 17     Fields:    Translation:AnimalsCells
    128. Solway J. What makes the airways contract abnormally? Is it inflammation? Am J Respir Crit Care Med. 2000 Mar; 161(3 Pt 2):S164-7. PMID: 10712367.
      Citations: 3     Fields:    Translation:Humans
    129. Hamann KJ, Vieira JE, Halayko AJ, Dorscheid D, White SR, Forsythe SM, Camoretti-Mercado B, Rabe KF, Solway J. Fas cross-linking induces apoptosis in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2000 Mar; 278(3):L618-24. PMID: 10710535.
      Citations: 12     Fields:    Translation:HumansCells
    130. Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, Daniel R, Newman DL, Wu X, Parry R, Lester LA, Solway J, Blumenthal M, King RA, Xu J, Meyers DA, Bleecker ER, Cox NJ. Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet. 2000 Feb; 66(2):517-26. PMID: 10677312; PMCID: PMC1288105.
      Citations: 63     Fields:    Translation:HumansCells
    131. Naureckas ET, Ndukwu IM, Halayko AJ, Maxwell C, Hershenson MB, Solway J. Bronchoalveolar lavage fluid from asthmatic subjects is mitogenic for human airway smooth muscle. Am J Respir Crit Care Med. 1999 Dec; 160(6):2062-6. PMID: 10588629.
      Citations: 28     Fields:    Translation:HumansCells
    132. Rouadi P, Baroody FM, Abbott D, Naureckas E, Solway J, Naclerio RM. A technique to measure the ability of the human nose to warm and humidify air. J Appl Physiol (1985). 1999 Jul; 87(1):400-6. PMID: 10409601.
      Citations: 29     Fields:    Translation:Humans
    133. Halayko AJ, Camoretti-Mercado B, Forsythe SM, Vieira JE, Mitchell RW, Wylam ME, Hershenson MB, Solway J. Divergent differentiation paths in airway smooth muscle culture: induction of functionally contractile myocytes. Am J Physiol. 1999 01; 276(1):L197-206. PMID: 9887072.
      Citations: 46     Fields:    Translation:AnimalsCells
    134. Solway J, Forsythe SM, Halayko AJ, Vieira JE, Hershenson MB, Camoretti-Mercado B. Transcriptional regulation of smooth muscle contractile apparatus expression. Am J Respir Crit Care Med. 1998 Nov; 158(5 Pt 3):S100-8. PMID: 9817732.
      Citations: 10     Fields:    Translation:HumansCells
    135. Padrid PA, Qin Y, Wells TN, Solway J, Camoretti-Mercado B. Sequence and structural analysis of feline interleukin-5 cDNA. Am J Vet Res. 1998 Oct; 59(10):1263-9. PMID: 9781459.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    136. Camoretti-Mercado B, Forsythe SM, LeBeau MM, Espinosa R, Vieira JE, Halayko AJ, Willadsen S, Kurtz B, Ober C, Evans GA, Thweatt R, Shapiro S, Niu Q, Qin Y, Padrid PA, Solway J. Expression and cytogenetic localization of the human SM22 gene (TAGLN). Genomics. 1998 May 01; 49(3):452-7. PMID: 9615232.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    137. Garland A, Necheles J, White SR, Neeley SP, Leff AR, Carson SS, Alger LE, McAllister K, Solway J. Activated eosinophils elicit substance P release from cultured dorsal root ganglion neurons. Am J Physiol. 1997 11; 273(5):L1096-102. PMID: 9374740.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    138. Solway J, Fredberg JJ. Perhaps airway smooth muscle dysfunction contributes to asthmatic bronchial hyperresponsiveness after all. Am J Respir Cell Mol Biol. 1997 Aug; 17(2):144-6. PMID: 9271301.
      Citations: 30     Fields:    Translation:HumansAnimals
    139. Fein AM, Branman SS, Casaburi R, Irvin CG, Make BJ, Rodarte JR, Solway J. Lung volume reduction surgery. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, May 1996. Am J Respir Crit Care Med. 1996 Oct; 154(4 Pt 1):1151-2. PMID: 8887620.
      Citations: 2     Fields:    Translation:Humans
    140. Girod CE, Shin DH, Hershenson MB, Solway J, Dahl R, Miller YE. p172: An alveolar type II and Clara cell specific protein with late developmental expression and upregulation by hyperoxic lung injury. Am J Respir Cell Mol Biol. 1996 Jun; 14(6):538-47. PMID: 8652182.
      Citations:    Fields:    Translation:AnimalsCells
    141. Girod CE, Shin DH, Hershenson MB, Solway J, Redlich CA, Gilman LB, Miller YE. 2A3 and 3F9. Novel lung epithelial antigens with early upregulation in hyperoxic and radiation lung injury models. Chest. 1996 Mar; 109(3 Suppl):33S. PMID: 8598142.
      Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
    142. Samaha FF, Ip HS, Morrisey EE, Seltzer J, Tang Z, Solway J, Parmacek MS. Developmental pattern of expression and genomic organization of the calponin-h1 gene. A contractile smooth muscle cell marker. J Biol Chem. 1996 Jan 05; 271(1):395-403. PMID: 8550594.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    143. Mitchell RW, Ndukwu IM, Herrnreiter A, Uzendoski K, Gitter B, Solway J, Leff AR. Differential tachykinin receptor subtype activation in capsaicin and KCl contractions of guinea pig trachealis. Am J Physiol. 1995 Dec; 269(6 Pt 1):L837-42. PMID: 8572245.
      Citations: 2     Fields:    Translation:Animals
    144. Gavriely N, Gaver DP, Solway J, Grotberg JB. Comparative study of intra-airway gas transport by alternative modes of ventilation. J Appl Physiol (1985). 1995 Nov; 79(5):1512-8. PMID: 8594007.
      Citations:    Fields:    Translation:Animals
    145. Hershenson MB, Chao TS, Abe MK, Gomes I, Kelleher MD, Solway J, Rosner MR. Histamine antagonizes serotonin and growth factor-induced mitogen-activated protein kinase activation in bovine tracheal smooth muscle cells. J Biol Chem. 1995 Aug 25; 270(34):19908-13. PMID: 7650005.
      Citations: 11     Fields:    Translation:AnimalsCells
    146. Solway J, Seltzer J, Samaha FF, Kim S, Alger LE, Niu Q, Morrisey EE, Ip HS, Parmacek MS. Structure and expression of a smooth muscle cell-specific gene, SM22 alpha. J Biol Chem. 1995 Jun 02; 270(22):13460-9. PMID: 7768949.
      Citations: 74     Fields:    Translation:AnimalsCells
    147. Kelleher MD, Abe MK, Chao TS, Jain M, Green JM, Solway J, Rosner MR, Hershenson MB. Role of MAP kinase activation in bovine tracheal smooth muscle mitogenesis. Am J Physiol. 1995 Jun; 268(6 Pt 1):L894-901. PMID: 7611431.
      Citations: 20     Fields:    Translation:AnimalsCells
    148. White SR, Garland A, Gitter B, Rodger I, Alger LE, Necheles J, Nawrocki AR, Solway J. Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells. Am J Physiol. 1995 Jun; 268(6 Pt 1):L957-65. PMID: 7611437.
      Citations: 1     Fields:    Translation:AnimalsCells
    149. Garland A, Jordan JE, Necheles J, Alger LE, Scully MM, Miller RJ, Ray DW, White SR, Solway J. Hypertonicity, but not hypothermia, elicits substance P release from rat C-fiber neurons in primary culture. J Clin Invest. 1995 May; 95(5):2359-66. PMID: 7537764; PMCID: PMC295856.
      Citations: 6     Fields:    Translation:AnimalsCells
    150. Naureckas ET, Hershenson MB, Abe MK, Kelleher MD, Florio C, Heisler SI, Absher M, Evans JN, Samsel RW, Solway J. Bronchoalveolar lavage fluid from immature rats with hyperoxia-induced airway remodeling is mitogenic for airway smooth muscle. Am J Respir Cell Mol Biol. 1995 Mar; 12(3):268-74. PMID: 7873192.
      Citations: 1     Fields:    Translation:AnimalsCells
    151. Solway J, Hershenson MB. Structural and functional abnormalities of the airways of hyperoxia-exposed immature rats. Chest. 1995 Mar; 107(3 Suppl):89S-93S. PMID: 7875011.
      Citations: 2     Fields:    Translation:Animals
    152. Kelleher MD, Naureckas ET, Solway J, Hershenson MB. In vivo hyperoxic exposure increases cultured lung fibroblast proliferation and c-Ha-ras expression. Am J Respir Cell Mol Biol. 1995 Jan; 12(1):19-26. PMID: 7811467.
      Citations: 4     Fields:    Translation:AnimalsCells
    153. Padrid P, Snook S, Finucane T, Shiue P, Cozzi P, Solway J, Leff AR. Persistent airway hyperresponsiveness and histologic alterations after chronic antigen challenge in cats. Am J Respir Crit Care Med. 1995 Jan; 151(1):184-93. PMID: 7812551.
      Citations: 46     Fields:    Translation:AnimalsCellsPHPublic Health
    154. Abe MK, Chao TS, Solway J, Rosner MR, Hershenson MB. Hydrogen peroxide stimulates mitogen-activated protein kinase in bovine tracheal myocytes: implications for human airway disease. Am J Respir Cell Mol Biol. 1994 Nov; 11(5):577-85. PMID: 7946386.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    155. Hershenson MB, Kelleher MD, Naureckas ET, Abe MK, Rubinstein VJ, Zimmermann A, Bendele AM, McNulty JA, Panettieri RA, Solway J. Hyperoxia increases airway cell S-phase traversal in immature rats in vivo. Am J Respir Cell Mol Biol. 1994 Sep; 11(3):296-303. PMID: 8086167.
      Citations: 6     Fields:    Translation:AnimalsCells
    156. Hershenson MB, Abe MK, Kelleher MD, Naureckas ET, Garland A, Zimmermann A, Rubinstein VJ, Solway J. Recovery of airway structure and function after hyperoxic exposure in immature rats. Am J Respir Crit Care Med. 1994 Jun; 149(6):1663-9. PMID: 8004327.
      Citations: 12     Fields:    Translation:HumansAnimals
    157. Yap DY, Liebkemann WD, Solway J, Gaver DP. Influences of parenchymal tethering on the reopening of closed pulmonary airways. J Appl Physiol (1985). 1994 May; 76(5):2095-105. PMID: 8063673.
      Citations: 12     Fields:    Translation:Animals
    158. Ndukwu IM, Solway J, Arbetter K, Uzendoski K, Leff AR, Mitchell RW. Immune sensitization augments epithelium-dependent spontaneous tone in guinea pig trachealis. Am J Physiol. 1994 May; 266(5 Pt 1):L485-92. PMID: 8203543.
      Citations: 2     Fields:    Translation:AnimalsPHPublic Health
    159. Murphy TM, Ray DW, Alger LE, Phillips IJ, Roach JC, Leff AR, Solway J. Ontogeny of dry gas hyperpnea-induced bronchoconstriction in guinea pigs. J Appl Physiol (1985). 1994 Mar; 76(3):1150-5. PMID: 8005858.
      Citations: 2     Fields:    Translation:AnimalsCells
    160. Naureckas ET, Dawson CA, Gerber BS, Gaver DP, Gerber HL, Linehan JH, Solway J, Samsel RW. Airway reopening pressure in isolated rat lungs. J Appl Physiol (1985). 1994 Mar; 76(3):1372-7. PMID: 8005884.
      Citations: 11     Fields:    Translation:Animals
    161. Hershenson MB, Wylam ME, Punjabi N, Umans JG, Schumacker PT, Mitchell RW, Solway J. Exposure of immature rats to hyperoxia increases tracheal smooth muscle stress generation in vitro. J Appl Physiol (1985). 1994 Feb; 76(2):743-9. PMID: 8175585.
      Citations: 3     Fields:    Translation:Animals
    162. Garland A, Jordan JE, Ray DW, Spaethe SM, Alger L, Solway J. Role of eicosanoids in hyperpnea-induced airway responses in guinea pigs. J Appl Physiol (1985). 1993 Dec; 75(6):2797-804. PMID: 8125904.
      Citations: 1     Fields:    Translation:Animals
    163. Mitchell RW, Ndukwu IM, Arbetter K, Solway J, Leff AR. Effect of airway inflammation on smooth muscle shortening and contractility in guinea pig trachealis. Am J Physiol. 1993 Dec; 265(6 Pt 1):L549-54. PMID: 8279571.
      Citations: 4     Fields:    Translation:Animals
    164. Hsiue TR, Leff AR, Garland A, Hershenson MB, Ray DW, Solway J. Impaired sensorineural function after allergen-induced mediator release. Am Rev Respir Dis. 1993 Aug; 148(2):447-54. PMID: 7688201.
      Citations: 2     Fields:    Translation:AnimalsCells
    165. Solway J, Kao BM, Jordan JE, Gitter B, Rodger IW, Howbert JJ, Alger LE, Necheles J, Leff AR, Garland A. Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs. J Clin Invest. 1993 Jul; 92(1):315-23. PMID: 8392088; PMCID: PMC293598.
      Citations: 3     Fields:    Translation:Animals
    166. Gavriely N, Solway J, Elad D, Shabtai-Musih Y, Gaver DP, Grotberg JB, Drazen JM. Construction and uses of a concentric catheter for gas sampling in lung airways. J Appl Physiol (1985). 1993 Jun; 74(6):3063-7. PMID: 8366009.
      Citations:    Fields:    Translation:Animals
    167. White SR, Hershenson MB, Sigrist KS, Zimmermann A, Solway J. Proliferation of guinea pig tracheal epithelial cells induced by calcitonin gene-related peptide. Am J Respir Cell Mol Biol. 1993 Jun; 8(6):592-6. PMID: 8323744.
      Citations: 14     Fields:    Translation:AnimalsCells
    168. Padrid P, Wolf R, Munoz NM, Spaethe S, Finucane T, Solway J, Leff AR. Augmented muscarinic responsiveness caused by 5-lipoxygenase products secreted from alveolar macrophages in isolated-perfused rat lung. Am Rev Respir Dis. 1993 Jun; 147(6 Pt 1):1514-20. PMID: 8503563.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    169. Munoz NM, Hamann KJ, Vita A, Cozzi PJ, Baranowski S, Solway J, Leff AR. Activation of tracheal smooth muscle responsiveness by fMLP-treated HL-60 cells and neutrophils. Am J Physiol. 1993 Mar; 264(3 Pt 1):L222-8. PMID: 8460711.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    170. Hershenson MB, Garland A, Kelleher MD, Zimmermann A, Hernandez C, Solway J. Hyperoxia-induced airway remodeling in immature rats. Correlation with airway responsiveness. Am Rev Respir Dis. 1992 Nov; 146(5 Pt 1):1294-300. PMID: 1443886.
      Citations: 6     Fields:    Translation:Animals
    171. Hsiue TR, Garland A, Ray DW, Hershenson MB, Leff AR, Solway J. Endogenous sensory neuropeptide release enhances nonspecific airway responsiveness in guinea pigs. Am Rev Respir Dis. 1992 Jul; 146(1):148-53. PMID: 1320818.
      Citations: 7     Fields:    Translation:AnimalsCells
    172. Hershenson MB, Aghili S, Punjabi N, Hernandez C, Ray DW, Garland A, Glagov S, Solway J. Hyperoxia-induced airway hyperresponsiveness and remodeling in immature rats. Am J Physiol. 1992 Mar; 262(3 Pt 1):L263-9. PMID: 1550249.
      Citations: 14     Fields:    Translation:Animals
    173. Gaver DP, Solway J, Punjabi N, Elad D, Grotberg JB, Gavriely N. Gas dispersion in volume-cycled tube flow. II. Tracer bolus experiments. J Appl Physiol (1985). 1992 Jan; 72(1):321-31. PMID: 1537733.
      Citations: 2     Fields:    Translation:Cells
    174. Solway J, Leff AR. Sensory neuropeptides and airway function. J Appl Physiol (1985). 1991 Dec; 71(6):2077-87. PMID: 1663932.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    175. Ray DW, Garland A, Hernandez C, Eappen S, Alger L, Solway J. Time course of bronchoconstriction induced by dry gas hyperpnea in guinea pigs. J Appl Physiol (1985). 1991 Feb; 70(2):504-10. PMID: 2022539.
      Citations: 1     Fields:    Translation:Animals
    176. Garland A, Ray DW, Doerschuk CM, Alger L, Eappon S, Hernandez C, Jackson M, Solway J. Role of tachykinins in hyperpnea-induced bronchovascular hyperpermeability in guinea pigs. J Appl Physiol (1985). 1991 Jan; 70(1):27-35. PMID: 2010383.
      Citations: 3     Fields:    Translation:Animals
    177. Solway J. Airway heat and water fluxes and the tracheobronchial circulation. Eur Respir J Suppl. 1990 Dec; 12:608s-617s. PMID: 2076155.
      Citations:    Fields:    Translation:HumansAnimals
    178. Ray DW, Eappen S, Hernandez C, Jackson M, Alger LE, Leff AR, Solway J. Distribution of airway narrowing during hyperpnea-induced bronchoconstriction in guinea pigs. J Appl Physiol (1985). 1990 Oct; 69(4):1323-9. PMID: 2262449.
      Citations: 1     Fields:    Translation:Animals
    179. White SR, Ohno S, Munoz NM, Gleich GJ, Abrahams C, Solway J, Leff AR. Epithelium-dependent contraction of airway smooth muscle caused by eosinophil MBP. Am J Physiol. 1990 Oct; 259(4 Pt 1):L294-303. PMID: 2221089.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    180. Gaver DP, Samsel RW, Solway J. Effects of surface tension and viscosity on airway reopening. J Appl Physiol (1985). 1990 Jul; 69(1):74-85. PMID: 2394665.
      Citations: 47     Fields:    Translation:Humans
    181. Ingenito EP, Pichurko BM, Lafleur J, Drazen JM, Ingram RH, Solway J. Breathing pattern affects respiratory heat loss but not bronchoconstrictor response in asthma. Lung. 1990; 168(1):23-34. PMID: 2105410.
      Citations: 1     Fields:    Translation:Humans
    182. Ray DW, Ingenito EP, Strek M, Schumacker PT, Solway J. Longitudinal distribution of canine respiratory heat and water exchanges. J Appl Physiol (1985). 1989 Jun; 66(6):2788-98. PMID: 2745342.
      Citations: 4     Fields:    Translation:Animals
    183. Schumacker PT, Samsel RW, Sznajder JI, Wood LD, Solway J. Gas density dependence of regional VA/V and VA/Q inequality during constant-flow ventilation. J Appl Physiol (1985). 1989 Apr; 66(4):1722-9. PMID: 2659575.
      Citations:    Fields:    Translation:Animals
    184. Ray DW, Hernandez C, Leff AR, Drazen JM, Solway J. Tachykinins mediate bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs. J Appl Physiol (1985). 1989 Mar; 66(3):1108-12. PMID: 2496085.
      Citations: 3     Fields:    Translation:Animals
    185. Schumacker PT, Solway J, Wood LD, Sznajder JI. Lobar contribution to VA/Q inequality during constant-flow ventilation. J Appl Physiol (1985). 1988 Nov; 65(5):2132-7. PMID: 3145277.
      Citations:    Fields:    Translation:Animals
    186. Anderson S, Butler J, Cole P, McFadden R, Pare P, Solway J. Air conditioning and exercise-induced asthma. Am Rev Respir Dis. 1988 Oct; 138(4):1064-5. PMID: 3202437.
      Citations:    Fields:    Translation:Humans
    187. Ingenito E, Solway J, Lafleur J, Lombardo A, Drazen JM, Pichurko B. Dissociation of temperature-gradient and evaporative heat loss during cold gas hyperventilation in cold-induced asthma. Am Rev Respir Dis. 1988 Sep; 138(3):540-6. PMID: 3202410.
      Citations: 5     Fields:    Translation:Humans
    188. Ray DW, Hernandez C, Munoz N, Leff AR, Solway J. Bronchoconstriction elicited by isocapnic hyperpnea in guinea pigs. J Appl Physiol (1985). 1988 Aug; 65(2):934-9. PMID: 3170439.
      Citations: 4     Fields:    Translation:Animals
    189. Nahum A, Sznajder JI, Solway J, Wood LD, Schumacker PT. Pressure, flow, and density relationships in airway models during constant-flow ventilation. J Appl Physiol (1985). 1988 May; 64(5):2066-73. PMID: 3391905.
      Citations: 4     Fields:    
    190. Solway J. Properties of steady maximal expiratory flow within excised canine central airways. J Appl Physiol (1985). 1988 Apr; 64(4):1650-8. PMID: 3378999.
      Citations: 1     Fields:    Translation:Animals
    191. Ingenito EP, Solway J, McFadden ER, Pichurko B, Bowman HF, Michaels D, Drazen JM. Indirect assessment of mucosal surface temperatures in the airways: theory and tests. J Appl Physiol (1985). 1987 Nov; 63(5):2075-83. PMID: 3693240.
      Citations: 30     Fields:    Translation:HumansAnimals
    192. Solway J, Fredberg JJ, Ingram RH, Pedersen OF, Drazen JM. Interdependent regional lung emptying during forced expiration: a transistor model. J Appl Physiol (1985). 1987 May; 62(5):2013-25. PMID: 3597273.
      Citations: 3     Fields:    Translation:HumansAnimals
    193. Shioya T, Solway J, Munoz NM, Mack M, Leff AR. Distribution of airway contractile responses within the major diameter bronchi during exogenous bronchoconstriction. Am Rev Respir Dis. 1987 May; 135(5):1105-11. PMID: 3555187.
      Citations: 4     Fields:    Translation:Animals
    194. Ludwig MS, Dreshaj I, Solway J, Munoz A, Ingram RH. Partitioning of pulmonary resistance during constriction in the dog: effects of volume history. J Appl Physiol (1985). 1987 Feb; 62(2):807-15. PMID: 3558240.
      Citations: 12     Fields:    Translation:Animals
    195. Davidson AB, Lee TH, Scanlon PD, Solway J, McFadden ER, Ingram RH, Corey EJ, Austen KF, Drazen JM. Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects. Am Rev Respir Dis. 1987 Feb; 135(2):333-7. PMID: 3028218.
      Citations: 36     Fields:    Translation:Humans
    196. Ingenito EP, Solway J, McFadden ER, Pichurko BM, Cravalho EG, Drazen JM. Finite difference analysis of respiratory heat transfer. J Appl Physiol (1985). 1986 Dec; 61(6):2252-9. PMID: 3804930.
      Citations: 12     Fields:    Translation:Humans
    197. Drazen JM, Dreshaij I, Ingram RH, Khoo M, Kamm R, Solway J. CO2 elimination by high-frequency oscillation: effects of vagosympathetic stimulation. J Appl Physiol (1985). 1986 Nov; 61(5):1836-42. PMID: 3781992.
      Citations:    Fields:    Translation:Animals
    198. Solway J, Leff AR, Dreshaj I, Munoz NM, Ingenito EP, Michaels D, Ingram RH, Drazen JM. Circulatory heat sources for canine respiratory heat exchange. J Clin Invest. 1986 Oct; 78(4):1015-9. PMID: 3760181; PMCID: PMC423747.
      Citations: 4     Fields:    Translation:Animals
    199. Solway J, Rossing TH, Saari AF, Drazen JM. Expiratory flow limitation and dynamic pulmonary hyperinflation during high-frequency ventilation. J Appl Physiol (1985). 1986 Jun; 60(6):2071-8. PMID: 3722072.
      Citations: 8     Fields:    Translation:Humans
    200. Solway J, Pichurko BM, Ingenito EP, McFadden ER, Fanta CH, Ingram RH, Drazen JM. Breathing pattern affects airway wall temperature during cold air hyperpnea in humans. Am Rev Respir Dis. 1985 Oct; 132(4):853-7. PMID: 4051320.
      Citations: 9     Fields:    Translation:Humans
    201. Solway J, Fanta CH. Differential inhibition of bronchoconstriction by the calcium channel blockers, verapamil and nifedipine. Am Rev Respir Dis. 1985 Sep; 132(3):666-70. PMID: 4037540.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    202. Gavriely N, Solway J, Loring SH, Butler JP, Slutsky AS, Drazen JM. Pressure-flow relationships of endotracheal tubes during high-frequency ventilation. J Appl Physiol (1985). 1985 Jul; 59(1):3-11. PMID: 4030576.
      Citations: 2     Fields:    Translation:Animals
    203. Solway J, Gavriely N, Slutsky AS, Rossing TH, Drinker P, Saari AF, Drazen JM. Effect of bias flow rate on gas transport during high-frequency oscillatory ventilation. Respir Physiol. 1985 May; 60(2):267-76. PMID: 4012095.
      Citations: 1     Fields:    Translation:Animals
    204. McFadden ER, Pichurko BM, Bowman HF, Ingenito E, Burns S, Dowling N, Solway J. Thermal mapping of the airways in humans. J Appl Physiol (1985). 1985 Feb; 58(2):564-70. PMID: 3980358.
      Citations: 129     Fields:    Translation:Humans
    205. Gavriely N, Solway J, Drazen JM, Slutsky AS, Brown R, Loring SH, Ingram RH. Radiographic visualization of airway wall movement during oscillatory flow in dogs. J Appl Physiol (1985). 1985 Feb; 58(2):645-52. PMID: 3980367.
      Citations: 2     Fields:    Translation:Animals
    206. Pichurko BM, McFadden ER, Bowman HF, Solway J, Burns S, Dowling N. Influence of cromolyn sodium on airway temperature in normal subjects. Am Rev Respir Dis. 1984 Dec; 130(6):1002-5. PMID: 6439086.
      Citations: 1     Fields:    Translation:Humans
    207. Khoo MC, Slutsky AS, Drazen JM, Solway J, Gavriely N, Kamm RD. Gas mixing during high-frequency ventilation: an improved model. J Appl Physiol Respir Environ Exerc Physiol. 1984 Aug; 57(2):493-506. PMID: 6432754.
      Citations: 4     Fields:    
    208. Saari AF, Rossing TH, Solway J, Drazen JM. Lung inflation during high-frequency ventilation. Am Rev Respir Dis. 1984 Feb; 129(2):333-6. PMID: 6696330.
      Citations: 16     Fields:    Translation:Humans
    209. Solway J, Gavriely N, Kamm RD, Drazen JM, Ingram RH, Khoo MC, Brown R, Slutsky AS. Intra-airway gas mixing during high-frequency ventilation. J Appl Physiol Respir Environ Exerc Physiol. 1984 Feb; 56(2):343-54. PMID: 6706747.
      Citations: 4     Fields:    Translation:Humans
    210. Solway J. Calcium channel blocking agents in bronchial hyperreactivity. J Asthma. 1984; 21(6):419-26. PMID: 6396294.
      Citations:    Fields:    Translation:Humans
    211. Rossing TH, Solway J, Saari AF, Gavriely N, Slutsky AS, Lehr JL, Drazen JM. Influence of the endotracheal tube on CO2 transport during high-frequency ventilation. Am Rev Respir Dis. 1984 Jan; 129(1):54-7. PMID: 6422812.
      Citations:    Fields:    Translation:Humans
    212. Solway J, McDonald M, Bunn HF, Aun F, Cole R, Soeldner JS. Biosynthesis of glycosylated hemoglobins in the monkey. J Lab Clin Med. 1979 Jun; 93(6):962-72. PMID: 108346.
      Citations: 1     Fields:    Translation:HumansAnimals
    213. McDonald MJ, Shapiro R, Bleichman M, Solway J, Bunn HF. Glycosylated minor components of human adult hemoglobin. Purification, identification, and partial structural analysis. J Biol Chem. 1978 Apr 10; 253(7):2327-32. PMID: 632272.
      Citations: 26     Fields:    Translation:HumansCells
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