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Marvin W. Makinen

TitleProfessor
InstitutionUniversity of Chicago
DepartmentBiochemistry and Molecular Biology
AddressChicago IL 60637
Phone+1 (773) 7021080
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Broder BA, Bhuiyan M, Freifelder R, Rotsch DA, Chitneni SK, Makinen MW, Chen CT. Efficient Synthesis and HPLC-Based Characterization for Developing Vanadium-48-Labeled Vanadyl Acetylacetonate as a Novel Cancer Radiotracer for PET Imaging. Molecules. 2024 Feb 09; 29(4). PMID: 38398551; PMCID: PMC10892645.
      Citations:    Fields:    Translation:Animals
    2. Broder BA, Bhuiyan MP, Freifelder R, Zhang HJ, Kucharski A, Makinen MW, Rotsch DA, Chen CT. Preliminary investigation of 48V-labeled VO(acac)2 for cancer imaging: An initial proof-of-concept study. Appl Radiat Isot. 2022 Aug; 186:110270. PMID: 35569262.
      Citations: 1     Fields:    Translation:Humans
    3. Hon J, Hwang MS, Charnetzki MA, Rashed IJ, Brady PB, Quillin S, Makinen MW. Kinetic characterization of the inhibition of protein tyrosine phosphatase-1B by Vanadyl (VO2+) chelates. J Biol Inorg Chem. 2017 Dec; 22(8):1267-1279. PMID: 29071441; PMCID: PMC5671894.
      Citations: 2     Fields:    Translation:Cells
    4. Makinen MW, Salehitazangi M. The Structural Basis of Action of Vanadyl (VO2+) Chelates in Cells. Coord Chem Rev. 2014 Nov 01; 279:1-22. PMID: 25237207; PMCID: PMC4163958.
      Citations: 11     
    5. Makinen MW, Bamba R, Ikejimba L, Wietholt C, Chen CT, Conzen SD. The vanadyl chelate bis(acetylacetonato)oxovanadium(IV) increases the fractional uptake of 2-(fluorine-18)-2-deoxy-D-glucose by cultured human breast carcinoma cells. Dalton Trans. 2013 Sep 07; 42(33):11862-7. PMID: 23644715; PMCID: PMC3733664.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    6. Mustafi D, Peng B, Foxley S, Makinen MW, Karczmar GS, Zamora M, Ejnik J, Martin H. New vanadium-based magnetic resonance imaging probes: clinical potential for early detection of cancer. J Biol Inorg Chem. 2009 Nov; 14(8):1187-97. PMID: 19572156.
      Citations: 11     Fields:    Translation:HumansAnimals
    7. Mustafi D, Smith CM, Makinen MW, Lee RC. Multi-block poloxamer surfactants suppress aggregation of denatured proteins. Biochim Biophys Acta. 2008 Jan; 1780(1):7-15. PMID: 17951011.
      Citations: 11     Fields:    Translation:AnimalsCells
    8. Walsh AM, Mustafi D, Makinen MW, Lee RC. A surfactant copolymer facilitates functional recovery of heat-denatured lysozyme. Ann N Y Acad Sci. 2005 Dec; 1066:321-7. PMID: 16533935.
      Citations: 5     Fields:    Translation:AnimalsCells
    9. Ou H, Yan L, Mustafi D, Makinen MW, Brady MJ. The vanadyl (VO2+) chelate bis(acetylacetonato)oxovanadium(IV) potentiates tyrosine phosphorylation of the insulin receptor. J Biol Inorg Chem. 2005 Dec; 10(8):874-86. PMID: 16235045.
      Citations: 16     Fields:    Translation:AnimalsCells
    10. Mustafi D, Makinen MW. Structure and conformation of bis(acetylacetonato)oxovanadium(IV) and bis(maltolato)oxovanadium(IV) in solution determined by electron nuclear double resonance spectroscopy. Inorg Chem. 2005 Aug 08; 44(16):5580-90. PMID: 16060607.
      Citations: 8     Fields:    Translation:Cells
    11. Savard PY, Sosa-Peinado A, Levesque RC, Makinen MW, Gagné SM. 1H, 13C and 15N backbone resonance assignments for TEM-1, a 28.9 kDa beta-lactamase from E. coli. J Biomol NMR. 2004 Jul; 29(3):433-4. PMID: 15213455.
      Citations: 3     Fields:    Translation:Cells
    12. Mustafi D, Hofer JE, Huang W, Palzkill T, Makinen MW. Chromophoric spin-labeled beta-lactam antibiotics for ENDOR structural characterization of reaction intermediates of class A and class C beta-lactamases. Spectrochim Acta A Mol Biomol Spectrosc. 2004 May; 60(6):1279-89. PMID: 15134725.
      Citations: 1     Fields:    Translation:Cells
    13. Mustafi D, Bekesi A, Vertessy BG, Makinen MW. Catalytic and structural role of the metal ion in dUTP pyrophosphatase. Proc Natl Acad Sci U S A. 2003 May 13; 100(10):5670-5. PMID: 12721364; PMCID: PMC156259.
      Citations: 16     Fields:    Translation:Cells
    14. Makinen MW, Brady MJ. Structural origins of the insulin-mimetic activity of bis(acetylacetonato)oxovanadium(IV). J Biol Chem. 2002 Apr 05; 277(14):12215-20. PMID: 11815612.
      Citations: 14     Fields:    Translation:AnimalsCells
    15. Mustafi D, Sosa-Peinado A, Gupta V, Gordon DJ, Makinen MW. Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy. Biochemistry. 2002 Jan 22; 41(3):797-808. PMID: 11790101.
      Citations: 1     Fields:    Translation:Cells
    16. Banerjee A, Makinen MW, Rutthard H. Mg2+ is not catalytically required in the intrinsic and kirromycin-stimulated GTPase action of Thermus thermophilus EF-Tu. J Biol Chem. 2001 Jun 01; 276(22):18728-33. PMID: 11274193.
      Citations: 4     Fields:    Translation:Cells
    17. Mustafi D, Sosa-Peinado A, Makinen MW. ENDOR structural characterization of a catalytically competent acylenzyme reaction intermediate of wild-type TEM-1 beta-lactamase confirms glutamate-166 as the base catalyst. Biochemistry. 2001 Feb 27; 40(8):2397-409. PMID: 11327860.
      Citations: 4     Fields:    Translation:Cells
    18. Mustafi D, Nakagawa Y, Makinen MW. ENDOR studies of VO2+: probing protein-metal ion interactions in nephrocalcin. Cell Mol Biol (Noisy-le-grand). 2000 Dec; 46(8):1345-60. PMID: 11156480.
      Citations: 2     Fields:    Translation:AnimalsCells
    19. Sosa-Peinado A, Mustafi D, Makinen MW. Overexpression and biosynthetic deuterium enrichment of TEM-1 beta-lactamase for structural characterization by magnetic resonance methods. Protein Expr Purif. 2000 Jul; 19(2):235-45. PMID: 10873536.
      Citations: 14     Fields:    Translation:Cells
    20. Atanasov BP, Mustafi D, Makinen MW. Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases. Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7):3160-5. PMID: 10716727; PMCID: PMC16209.
      Citations: 29     Fields:    Translation:Cells
    21. Horvath MP, Copeland RA, Makinen MW. The second derivative electronic absorption spectrum of cytochrome c oxidase in the Soret region. Biophys J. 1999 Sep; 77(3):1694-711. PMID: 10465779; PMCID: PMC1300456.
      Citations:    Fields:    Translation:AnimalsCells
    22. Makinen MW. Electron nuclear double resonance determined structures of enzyme reaction intermediates: structural evidence for substrate destabilization. Spectrochim Acta A Mol Biomol Spectrosc. 1998 Dec; 54A(14):2269-81. PMID: 9974225.
      Citations:    Fields:    Translation:Cells
    23. Halpern HJ, Peric M, Yu C, Barth ED, Chandramouli GV, Makinen MW, Rosen GM. In vivo spin-label murine pharmacodynamics using low-frequency electron paramagnetic resonance imaging. Biophys J. 1996 Jul; 71(1):403-9. PMID: 8804623; PMCID: PMC1233491.
      Citations: 12     Fields:    Translation:AnimalsCells
    24. Makinen MW, Mustafi D. The vanadyl ion: molecular structure of coordinating ligands by electron paramagnetic resonance and electron nuclear double resonance spectroscopy. Met Ions Biol Syst. 1995; 31:89-127. PMID: 8564821.
      Citations: 4     Fields:    
    25. Wells GB, Mustafi D, Makinen MW. Structure at the active site of an acylenzyme of alpha-chymotrypsin and implications for the catalytic mechanism. An electron nuclear double resonance study. J Biol Chem. 1994 Feb 11; 269(6):4577-86. PMID: 8308029.
      Citations:    Fields:    Translation:Cells
    26. Mustafi D, Makinen MW. Catalytic conformation of carboxypeptidase A. Structure of a true enzyme reaction intermediate determined by electron nuclear double resonance. J Biol Chem. 1994 Feb 11; 269(6):4587-95. PMID: 8308030.
      Citations: 5     Fields:    Translation:Cells
    27. Boisvert WE, Mustafi D, Kasa S, Makinen MW, Halpern HJ, Yu C, Barth E, Peric M. Kinetically specific spin-label substrates of liver alcohol dehydrogenase and of liver aldehyde dehydrogenase. Adv Exp Med Biol. 1993; 328:501-12. PMID: 8388157.
      Citations:    Fields:    Translation:AnimalsCells
    28. Maret W, Makinen MW. The pH variation of steady-state kinetic parameters of site-specific Co(2+)-reconstituted liver alcohol dehydrogenase. A mechanistic probe for the assignment of metal-linked ionizations. J Biol Chem. 1991 Nov 05; 266(31):20636-44. PMID: 1939113.
      Citations: 3     Fields:    Translation:AnimalsCells
    29. Mustafi D, Boisvert WE, Makinen MW. Structure and conformation of the nitroxyl spin-label ethyl 3-(2,2,5,5-tetramethylpyrrolinyl-1-oxyl)-propen-2-oate determined by electron nuclear double resonance: comparison with the structure of a spin-label substrate of carboxypeptidase A. Biopolymers. 1990 Jan; 29(1):45-55. PMID: 2158361.
      Citations:    Fields:    Translation:Cells
    30. Mustafi D, Wells GB, Joela H, Makinen MW. Assignment of proton endor resonances of nitroxyl spin-labels in frozen solution. Free Radic Res Commun. 1990; 10(1-2):95-101. PMID: 2165991.
      Citations:    Fields:    
    31. Makinen MW, Troyer JM, van der Werff H, Berendsen HJ, van Gunsteren WF. Dynamical structure of carboxypeptidase A. J Mol Biol. 1989 May 05; 207(1):201-16. PMID: 2738924.
      Citations: 1     Fields:    Translation:AnimalsCells
    32. Metzler CM, Mitra J, Metzler DE, Makinen MW, Hyde CC, Rogers PH, Arnone A. Correlation of polarized absorption spectroscopic and X-ray diffraction studies of crystalline cytosolic aspartate aminotransferase of pig hearts. J Mol Biol. 1988 Sep 05; 203(1):197-220. PMID: 3184186.
      Citations: 3     Fields:    Translation:AnimalsCells
    33. Brorson JR, Novak ES, Makinen MW. Solvent structure and enzyme activity. J Biomol Struct Dyn. 1985 Aug; 3(1):197-204. PMID: 3917015.
      Citations:    Fields:    Translation:Cells
    34. Makinen MW, Sigountos CW. Structural basis and dynamics of the fiber-to-crystal transition of sickle cell hemoglobin. J Mol Biol. 1984 Sep 15; 178(2):439-76. PMID: 6492156.
      Citations: 4     Fields:    Translation:HumansCells
    35. Arnone A, Rogers PH, Hyde CC, Makinen MW, Feldhaus R, Metzler CM, Metzler DE. Crystallographic and chemical studies on cytosolic aspartate aminotransferase. Prog Clin Biol Res. 1984; 144B:171-93. PMID: 6425857.
      Citations: 1     Fields:    Translation:AnimalsCells
    36. Makinen MW, Wells GB, Kang SO. Structure and mechanism of carboxypeptidase A. Adv Inorg Biochem. 1984; 6:1-69. PMID: 6398961.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    37. Makinen MW, Maret W, Yim MB. Neutral metal-bound water is the base catalyst in liver alcohol dehydrogenase. Proc Natl Acad Sci U S A. 1983 May; 80(9):2584-8. PMID: 6302696; PMCID: PMC393870.
      Citations: 10     Fields:    Translation:AnimalsCells
    38. Kuo LC, Fukuyama JM, Makinen MW. Catalytic conformation of carboxypeptidase A. The structure of a true reaction intermediate stabilized at subzero temperatures. J Mol Biol. 1983 Jan 05; 163(1):63-105. PMID: 6300411.
      Citations: 2     Fields:    Translation:Cells
    39. Kuo LC, Makinen MW. Hydrolysis of esters by carboxypeptidase A requires a penta-coordinate metal ion. J Biol Chem. 1982 Jan 10; 257(1):24-7. PMID: 6273427.
      Citations: 9     Fields:    Translation:AnimalsCells
    40. Makinen MW, Yim MB. Coordination environment of the active-site metal ion of liver alcohol dehydrogenase. Proc Natl Acad Sci U S A. 1981 Oct; 78(10):6221-5. PMID: 6273859; PMCID: PMC349010.
      Citations: 9     Fields:    Translation:AnimalsCells
    41. Wilson SM, Makinen MW. Electron microscope study of the kinetics of the fiber-to-crystal transition of sickle cell hemoglobin. Proc Natl Acad Sci U S A. 1980 Feb; 77(2):944-8. PMID: 6928690; PMCID: PMC348399.
      Citations: 3     Fields:    Translation:HumansCells
    42. Koch TR, Kuo LC, Douglas EG, Jaffer S, Makinen MW. Synthesis of chromophoric, spin label enzyme substrates useful for cryoenzymology. J Biol Chem. 1979 Dec 25; 254(24):12310-3. PMID: 227892.
      Citations: 1     Fields:    Translation:AnimalsCells
    43. Makinen MW, Houtchens RA, Caughey WS. Structure of carboxymyoglobin in crystals and in solution. Proc Natl Acad Sci U S A. 1979 Dec; 76(12):6042-6. PMID: 293700; PMCID: PMC411796.
      Citations: 27     Fields:    Translation:AnimalsCells
    44. Makinen MW, Kuo LC, Dymowski JJ, Jaffer S. Catalytic role of the metal ion of carboxypeptidase A in ester hydrolysis. J Biol Chem. 1979 Jan 25; 254(2):356-66. PMID: 33168.
      Citations: 20     Fields:    Translation:AnimalsCells
    45. Makinen MW, Churg AK, Glick HA. Fe-O2 bonding and oxyheme structure in myoglobin. Proc Natl Acad Sci U S A. 1978 May; 75(5):2291-5. PMID: 276871; PMCID: PMC392538.
      Citations: 3     Fields:    Translation:AnimalsCells
    46. Ohtsuki M, White SL, Zeitler E, Wellems TE, Fuller SD, Zwick M, Makinen MW, Sigler PB. Electron microscopy of fibers and discs of hemoglobin S having sixfold symmetry. Proc Natl Acad Sci U S A. 1977 Dec; 74(12):5538-42. PMID: 271978; PMCID: PMC431798.
      Citations: 6     Fields:    Translation:HumansCells
    47. Makinen MW, Fink AL. Reactivity and cryoenzymology of enzymes in the crystalline state. Annu Rev Biophys Bioeng. 1977; 6:301-43. PMID: 194529.
      Citations: 18     Fields:    Translation:Cells
    48. Makinen MW, Yammura K, Kaiser ET. Mechanism of action of carboxypeptidase A in ester hydrolysis. Proc Natl Acad Sci U S A. 1976 Nov; 73(11):3882-6. PMID: 1069272; PMCID: PMC431251.
      Citations: 6     Fields:    Translation:Cells
    49. Genzel L, Keilmann F, Martin TP, Winterling G, Yacoby Y, Makinen MW, Fröhlich H. Low-frequency Raman spectra of lysozyme. Biopolymers. 1976 Jan; 15(1):219-25. PMID: 1244901.
      Citations: 14     Fields:    
    50. Eaton WA, Hofrichter J, Makinen MW, Andersen RD, Ludwig ML. Optical spectra and electronic structure of flavine mononucleotide in flavodoxin crystals. Biochemistry. 1975 May 20; 14(10):2146-51. PMID: 1148163.
      Citations: 8     Fields:    Translation:Cells
    51. Makinen MW, Eaton WA. Optically detected conformational changes in haemoglobin single crystals. Nature. 1974 Jan 04; 247(5435):62-4. PMID: 4808946.
      Citations: 9     Fields:    Translation:AnimalsCells
    52. Makinen MW, Eaton WA. Polarized single crystal absorption spectra of carboxy- and oxyhemoglobin. Ann N Y Acad Sci. 1973; 206:210-22. PMID: 4356180.
      Citations: 10     Fields:    Translation:AnimalsCells
    53. Makinen MW, Milstien JB, Kon H. Specificity of interaction of haptoglobin with mammalian hemoglobin. Biochemistry. 1972 Oct 10; 11(21):3851-60. PMID: 4342895.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    54. Makinen MW, Kon H. Circular dichroism and electron paramagnetic resonance of the haptoglobin-hemoglobin complex. Biochemistry. 1971 Jan 05; 10(1):43-52. PMID: 4321120.
      Citations: 1     Fields:    Translation:HumansCells
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