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Marvin W. Makinen

TitlePROFESSOR
InstitutionUniversity of Chicago
DepartmentBiochem/Mol Bio
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hon J, Hwang MS, Charnetzki MA, Rashed IJ, Brady PB, Quillin S, Makinen MW. Kinetic characterization of the inhibition of protein tyrosine phosphatase-1B by Vanadyl (VO2+) chelates. J Biol Inorg Chem. 2017 Dec; 22(8):1267-1279. PMID: 29071441.
      View in: PubMed
    2. Makinen MW, Salehitazangi M. The Structural Basis of Action of Vanadyl (VO2+) Chelates in Cells. Coord Chem Rev. 2014 Nov 01; 279:1-22. PMID: 25237207.
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    3. Makinen MW, Bamba R, Ikejimba L, Wietholt C, Chen CT, Conzen SD. The vanadyl chelate bis(acetylacetonato)oxovanadium(IV) increases the fractional uptake of 2-(fluorine-18)-2-deoxy-D-glucose by cultured human breast carcinoma cells. Dalton Trans. 2013 Sep 07; 42(33):11862-7. PMID: 23644715.
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    4. Mustafi D, Peng B, Foxley S, Makinen MW, Karczmar GS, Zamora M, Ejnik J, Martin H. New vanadium-based magnetic resonance imaging probes: clinical potential for early detection of cancer. J Biol Inorg Chem. 2009 Nov; 14(8):1187-97. PMID: 19572156.
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    5. Mustafi D, Smith CM, Makinen MW, Lee RC. Multi-block poloxamer surfactants suppress aggregation of denatured proteins. Biochim Biophys Acta. 2008 Jan; 1780(1):7-15. PMID: 17951011.
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    6. Walsh AM, Mustafi D, Makinen MW, Lee RC. A surfactant copolymer facilitates functional recovery of heat-denatured lysozyme. Ann N Y Acad Sci. 2005 Dec; 1066:321-7. PMID: 16533935.
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    7. Ou H, Yan L, Mustafi D, Makinen MW, Brady MJ. The vanadyl (VO2+) chelate bis(acetylacetonato)oxovanadium(IV) potentiates tyrosine phosphorylation of the insulin receptor. J Biol Inorg Chem. 2005 Dec; 10(8):874-86. PMID: 16235045.
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    8. Mustafi D, Makinen MW. Structure and conformation of bis(acetylacetonato)oxovanadium(IV) and bis(maltolato)oxovanadium(IV) in solution determined by electron nuclear double resonance spectroscopy. Inorg Chem. 2005 Aug 08; 44(16):5580-90. PMID: 16060607.
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    9. Savard PY, Sosa-Peinado A, Levesque RC, Makinen MW, Gagné SM. 1H, 13C and 15N backbone resonance assignments for TEM-1, a 28.9 kDa beta-lactamase from E. coli. J Biomol NMR. 2004 Jul; 29(3):433-4. PMID: 15213455.
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    10. Mustafi D, Hofer JE, Huang W, Palzkill T, Makinen MW. Chromophoric spin-labeled beta-lactam antibiotics for ENDOR structural characterization of reaction intermediates of class A and class C beta-lactamases. Spectrochim Acta A Mol Biomol Spectrosc. 2004 May; 60(6):1279-89. PMID: 15134725.
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    11. Mustafi D, Bekesi A, Vertessy BG, Makinen MW. Catalytic and structural role of the metal ion in dUTP pyrophosphatase. Proc Natl Acad Sci U S A. 2003 May 13; 100(10):5670-5. PMID: 12721364.
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    12. Makinen MW, Brady MJ. Structural origins of the insulin-mimetic activity of bis(acetylacetonato)oxovanadium(IV). J Biol Chem. 2002 Apr 05; 277(14):12215-20. PMID: 11815612.
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    13. Mustafi D, Sosa-Peinado A, Gupta V, Gordon DJ, Makinen MW. Structure of spin-labeled methylmethanethiolsulfonate in solution and bound to TEM-1 beta-lactamase determined by electron nuclear double resonance spectroscopy. Biochemistry. 2002 Jan 22; 41(3):797-808. PMID: 11790101.
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    14. Rutthard H, Banerjee A, Makinen MW. Mg2+ is not catalytically required in the intrinsic and kirromycin-stimulated GTPase action of Thermus thermophilus EF-Tu. J Biol Chem. 2001 Jun 01; 276(22):18728-33. PMID: 11274193.
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    15. Mustafi D, Sosa-Peinado A, Makinen MW. ENDOR structural characterization of a catalytically competent acylenzyme reaction intermediate of wild-type TEM-1 beta-lactamase confirms glutamate-166 as the base catalyst. Biochemistry. 2001 Feb 27; 40(8):2397-409. PMID: 11327860.
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    16. Mustafi D, Nakagawa Y, Makinen MW. ENDOR studies of VO2+: probing protein-metal ion interactions in nephrocalcin. Cell Mol Biol (Noisy-le-grand). 2000 Dec; 46(8):1345-60. PMID: 11156480.
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    17. Sosa-Peinado A, Mustafi D, Makinen MW. Overexpression and biosynthetic deuterium enrichment of TEM-1 beta-lactamase for structural characterization by magnetic resonance methods. Protein Expr Purif. 2000 Jul; 19(2):235-45. PMID: 10873536.
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    18. Atanasov BP, Mustafi D, Makinen MW. Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases. Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7):3160-5. PMID: 10716727.
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    19. Horvath MP, Copeland RA, Makinen MW. The second derivative electronic absorption spectrum of cytochrome c oxidase in the Soret region. Biophys J. 1999 Sep; 77(3):1694-711. PMID: 10465779.
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    20. Makinen MW. Electron nuclear double resonance determined structures of enzyme reaction intermediates: structural evidence for substrate destabilization. Spectrochim Acta A Mol Biomol Spectrosc. 1998 Dec; 54A(14):2269-81. PMID: 9974225.
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    21. Halpern HJ, Peric M, Yu C, Barth ED, Chandramouli GV, Makinen MW, Rosen GM. In vivo spin-label murine pharmacodynamics using low-frequency electron paramagnetic resonance imaging. Biophys J. 1996 Jul; 71(1):403-9. PMID: 8804623.
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    22. Makinen MW, Mustafi D. The vanadyl ion: molecular structure of coordinating ligands by electron paramagnetic resonance and electron nuclear double resonance spectroscopy. Met Ions Biol Syst. 1995; 31:89-127. PMID: 8564821.
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    23. Wells GB, Mustafi D, Makinen MW. Structure at the active site of an acylenzyme of alpha-chymotrypsin and implications for the catalytic mechanism. An electron nuclear double resonance study. J Biol Chem. 1994 Feb 11; 269(6):4577-86. PMID: 8308029.
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    24. Mustafi D, Makinen MW. Catalytic conformation of carboxypeptidase A. Structure of a true enzyme reaction intermediate determined by electron nuclear double resonance. J Biol Chem. 1994 Feb 11; 269(6):4587-95. PMID: 8308030.
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    25. Boisvert WE, Mustafi D, Kasa S, Makinen MW, Halpern HJ, Yu C, Barth E, Peric M. Kinetically specific spin-label substrates of liver alcohol dehydrogenase and of liver aldehyde dehydrogenase. Adv Exp Med Biol. 1993; 328:501-12. PMID: 8388157.
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    26. Maret W, Makinen MW. The pH variation of steady-state kinetic parameters of site-specific Co(2+)-reconstituted liver alcohol dehydrogenase. A mechanistic probe for the assignment of metal-linked ionizations. J Biol Chem. 1991 Nov 05; 266(31):20636-44. PMID: 1939113.
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    27. Mustafi D, Boisvert WE, Makinen MW. Structure and conformation of the nitroxyl spin-label ethyl 3-(2,2,5,5-tetramethylpyrrolinyl-1-oxyl)-propen-2-oate determined by electron nuclear double resonance: comparison with the structure of a spin-label substrate of carboxypeptidase A. Biopolymers. 1990 Jan; 29(1):45-55. PMID: 2158361.
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    28. Mustafi D, Wells GB, Joela H, Makinen MW. Assignment of proton endor resonances of nitroxyl spin-labels in frozen solution. Free Radic Res Commun. 1990; 10(1-2):95-101. PMID: 2165991.
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    29. Makinen MW, Troyer JM, van der Werff H, Berendsen HJ, van Gunsteren WF. Dynamical structure of carboxypeptidase A. J Mol Biol. 1989 May 05; 207(1):201-16. PMID: 2738924.
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    30. Metzler CM, Mitra J, Metzler DE, Makinen MW, Hyde CC, Rogers PH, Arnone A. Correlation of polarized absorption spectroscopic and X-ray diffraction studies of crystalline cytosolic aspartate aminotransferase of pig hearts. J Mol Biol. 1988 Sep 05; 203(1):197-220. PMID: 3184186.
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    31. Brorson JR, Novak ES, Makinen MW. Solvent structure and enzyme activity. J Biomol Struct Dyn. 1985 Aug; 3(1):197-204. PMID: 3917015.
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    32. Makinen MW, Sigountos CW. Structural basis and dynamics of the fiber-to-crystal transition of sickle cell hemoglobin. J Mol Biol. 1984 Sep 15; 178(2):439-76. PMID: 6492156.
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    33. Arnone A, Rogers PH, Hyde CC, Makinen MW, Feldhaus R, Metzler CM, Metzler DE. Crystallographic and chemical studies on cytosolic aspartate aminotransferase. Prog Clin Biol Res. 1984; 144B:171-93. PMID: 6425857.
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    34. Makinen MW, Wells GB, Kang SO. Structure and mechanism of carboxypeptidase A. Adv Inorg Biochem. 1984; 6:1-69. PMID: 6398961.
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    35. Makinen MW, Maret W, Yim MB. Neutral metal-bound water is the base catalyst in liver alcohol dehydrogenase. Proc Natl Acad Sci U S A. 1983 May; 80(9):2584-8. PMID: 6302696.
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    36. Kuo LC, Fukuyama JM, Makinen MW. Catalytic conformation of carboxypeptidase A. The structure of a true reaction intermediate stabilized at subzero temperatures. J Mol Biol. 1983 Jan 05; 163(1):63-105. PMID: 6300411.
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    37. Kuo LC, Makinen MW. Hydrolysis of esters by carboxypeptidase A requires a penta-coordinate metal ion. J Biol Chem. 1982 Jan 10; 257(1):24-7. PMID: 6273427.
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    38. Makinen MW, Yim MB. Coordination environment of the active-site metal ion of liver alcohol dehydrogenase. Proc Natl Acad Sci U S A. 1981 Oct; 78(10):6221-5. PMID: 6273859.
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    39. Wilson SM, Makinen MW. Electron microscope study of the kinetics of the fiber-to-crystal transition of sickle cell hemoglobin. Proc Natl Acad Sci U S A. 1980 Feb; 77(2):944-8. PMID: 6928690.
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    40. Koch TR, Kuo LC, Douglas EG, Jaffer S, Makinen MW. Synthesis of chromophoric, spin label enzyme substrates useful for cryoenzymology. J Biol Chem. 1979 Dec 25; 254(24):12310-3. PMID: 227892.
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    41. Makinen MW, Houtchens RA, Caughey WS. Structure of carboxymyoglobin in crystals and in solution. Proc Natl Acad Sci U S A. 1979 Dec; 76(12):6042-6. PMID: 293700.
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    42. Makinen MW, Kuo LC, Dymowski JJ, Jaffer S. Catalytic role of the metal ion of carboxypeptidase A in ester hydrolysis. J Biol Chem. 1979 Jan 25; 254(2):356-66. PMID: 33168.
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    43. Makinen MW, Churg AK, Glick HA. Fe-O2 bonding and oxyheme structure in myoglobin. Proc Natl Acad Sci U S A. 1978 May; 75(5):2291-5. PMID: 276871.
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    44. Ohtsuki M, White SL, Zeitler E, Wellems TE, Fuller SD, Zwick M, Makinen MW, Sigler PB. Electron microscopy of fibers and discs of hemoglobin S having sixfold symmetry. Proc Natl Acad Sci U S A. 1977 Dec; 74(12):5538-42. PMID: 271978.
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    45. Makinen MW, Fink AL. Reactivity and cryoenzymology of enzymes in the crystalline state. Annu Rev Biophys Bioeng. 1977; 6:301-43. PMID: 194529.
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    46. Makinen MW, Yammura K, Kaiser ET. Mechanism of action of carboxypeptidase A in ester hydrolysis. Proc Natl Acad Sci U S A. 1976 Nov; 73(11):3882-6. PMID: 1069272.
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    47. Genzel L, Keilmann F, Martin TP, Winterling G, Yacoby Y, Fröhlich H, Makinen MW. Low-frequency Raman spectra of lysozyme. Biopolymers. 1976 Jan; 15(1):219-25. PMID: 1244901.
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    48. Eaton WA, Hofrichter J, Makinen MW, Andersen RD, Ludwig ML. Optical spectra and electronic structure of flavine mononucleotide in flavodoxin crystals. Biochemistry. 1975 May 20; 14(10):2146-51. PMID: 1148163.
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    49. Makinen MW, Eaton WA. Optically detected conformational changes in haemoglobin single crystals. Nature. 1974 Jan 04; 247(5435):62-4. PMID: 4808946.
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    50. Makinen MW, Eaton WA. Polarized single crystal absorption spectra of carboxy- and oxyhemoglobin. Ann N Y Acad Sci. 1973; 206:210-22. PMID: 4356180.
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    51. Makinen MW, Milstien JB, Kon H. Specificity of interaction of haptoglobin with mammalian hemoglobin. Biochemistry. 1972 Oct 10; 11(21):3851-60. PMID: 4342895.
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    52. Makinen MW, Kon H. Circular dichroism and electron paramagnetic resonance of the haptoglobin-hemoglobin complex. Biochemistry. 1971 Jan 05; 10(1):43-52. PMID: 4321120.
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