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Andrzej Joachimiak

AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tan K, Teschler JK, Wu R, Jedrzejczak RP, Zhou M, Shuvalova LA, Endres MJ, Welk LF, Kwon K, Anderson WF, Satchell KJF, Yildiz FH, Joachimiak A. Sensor Domain of Histidine Kinase VxrA of Vibrio cholerae- A Hairpin-swapped Dimer and its Conformational Change. J Bacteriol. 2021 Mar 22. PMID: 33753465.
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    2. Kim Y, Wower J, Maltseva N, Chang C, Jedrzejczak R, Wilamowski M, Kang S, Nicolaescu V, Randall G, Michalska K, Joachimiak A. Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2. Commun Biol. 2021 02 09; 4(1):193. PMID: 33564093.
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    3. Osipiuk J, Azizi SA, Dvorkin S, Endres M, Jedrzejczak R, Jones KA, Kang S, Kathayat RS, Kim Y, Lisnyak VG, Maki SL, Nicolaescu V, Taylor CA, Tesar C, Zhang YA, Zhou Z, Randall G, Michalska K, Snyder SA, Dickinson BC, Joachimiak A. Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors. Nat Commun. 2021 02 02; 12(1):743. PMID: 33531496.
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    4. Guthmiller JJ, Stovicek O, Wang J, Changrob S, Li L, Halfmann P, Zheng NY, Utset H, Stamper CT, Dugan HL, Miller WD, Huang M, Dai YN, Nelson CA, Hall PD, Jansen M, Shanmugarajah K, Donington JS, Krammer F, Fremont DH, Joachimiak A, Kawaoka Y, Tesic V, Madariaga ML, Wilson PC. SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike. mBio. 2021 01 19; 12(1). PMID: 33468695.
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    5. Guthmiller JJ, Stovicek O, Wang J, Changrob S, Li L, Halfmann P, Zheng NY, Utset H, Stamper CT, Dugan HL, Miller WD, Huang M, Dai YN, Nelson CA, Hall PD, Jansen M, Shanmugarajah K, Donington JS, Krammer F, Fremont DH, Joachimiak A, Kawaoka Y, Tesic V, Madariaga ML, Wilson PC. SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike. bioRxiv. 2020 Sep 13. PMID: 32935099.
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    6. Michalska K, Kim Y, Jedrzejczak R, Maltseva NI, Stols L, Endres M, Joachimiak A. Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. IUCrJ. 2020 Sep 01; 7(Pt 5):814-824. PMID: 32939273.
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    7. Kim Y, Jedrzejczak R, Maltseva NI, Wilamowski M, Endres M, Godzik A, Michalska K, Joachimiak A. Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2. Protein Sci. 2020 07; 29(7):1596-1605. PMID: 32304108.
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    8. Rosas-Lemus M, Minasov G, Shuvalova L, Inniss NL, Kiryukhina O, Wiersum G, Kim Y, Jedrzejczak R, Maltseva NI, Endres M, Jaroszewski L, Godzik A, Joachimiak A, Satchell KJF. The crystal structure of nsp10-nsp16 heterodimer from SARS-CoV-2 in complex with S-adenosylmethionine. bioRxiv. 2020 Apr 26. PMID: 32511376.
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    9. Michalska K, Chang C, Maltseva NI, Jedrzejczak R, Robertson GT, Gusovsky F, McCarren P, Schreiber SL, Nag PP, Joachimiak A. Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase. Protein Sci. 2020 03; 29(3):779-788. PMID: 31930594.
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    10. Kim Y, Maltseva N, Wilamowski M, Tesar C, Endres M, Joachimiak A. Structural and biochemical analysis of the metallo-ß-lactamase L1 from emerging pathogen Stenotrophomonas maltophilia revealed the subtle but distinct di-metal scaffold for catalytic activity. Protein Sci. 2020 03; 29(3):723-743. PMID: 31846104.
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    11. Filippova EV, Kuhn ML, Osipiuk J, Kiryukhina O, Joachimiak A, Ballicora MA, Anderson WF. Corrigendum to "A Novel Polyamine Allosteric Site of SpeG from Vibrio Cholerae is Revealed by its Dodecameric Structure" [J. Mol. Biol. 427 (6 Part B) (2015) 1316-1334]. J Mol Biol. 2019 Nov 08; 431(22):4527. PMID: 31653437.
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    12. Fang X, Osipiuk J, Chakravarthy S, Yuan M, Menzer WM, Nissen D, Liang P, Raba DA, Tuz K, Howard AJ, Joachimiak A, Minh DDL, Juarez O. Conserved residue His-257 of Vibrio cholerae flavin transferase ApbE plays a critical role in substrate binding and catalysis. J Biol Chem. 2019 09 13; 294(37):13800-13810. PMID: 31350338.
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    13. Michalska K, Gale J, Joachimiak G, Chang C, Hatzos-Skintges C, Nocek B, Johnston SE, Bigelow L, Bajrami B, Jedrzejczak RP, Wellington S, Hung DT, Nag PP, Fisher SL, Endres M, Joachimiak A. Conservation of the structure and function of bacterial tryptophan synthases. IUCrJ. 2019 Jul 01; 6(Pt 4):649-664. PMID: 31316809.
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    14. Michalska K, Zhang K, March ZM, Hatzos-Skintges C, Pintilie G, Bigelow L, Castellano LM, Miles LJ, Jackrel ME, Chuang E, Jedrzejczak R, Shorter J, Chiu W, Joachimiak A. Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events. Structure. 2019 03 05; 27(3):449-463.e7. PMID: 30595457.
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    15. Tan K, Deatherage Kaiser BL, Wu R, Cuff M, Fan Y, Bigelow L, Jedrzejczak RP, Adkins JN, Cort JR, Babnigg G, Joachimiak A. Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi. Protein Sci. 2017 Sep; 26(9):1738-1748. PMID: 28580643.
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    16. Sachleben JR, Adhikari AN, Gawlak G, Hoey RJ, Liu G, Joachimiak A, Montelione GT, Sosnick TR, Koide S. Aromatic claw: A new fold with high aromatic content that evades structural prediction. Protein Sci. 2017 02; 26(2):208-217. PMID: 27750371.
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    17. Makowska-Grzyska M, Kim Y, Gorla SK, Wei Y, Mandapati K, Zhang M, Maltseva N, Modi G, Boshoff HI, Gu M, Aldrich C, Cuny GD, Hedstrom L, Joachimiak A. Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds. PLoS One. 2015; 10(10):e0138976. PMID: 26440283.
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    18. Filippova EV, Weigand S, Osipiuk J, Kiryukhina O, Joachimiak A, Anderson WF. Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG. J Mol Biol. 2015 Nov 06; 427(22):3538-3553. PMID: 26410587.
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    19. Starus A, Nocek B, Bennett B, Larrabee JA, Shaw DL, Sae-Lee W, Russo MT, Gillner DM, Makowska-Grzyska M, Joachimiak A, Holz RC. Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril. Biochemistry. 2015 Aug 11; 54(31):4834-44. PMID: 26186504.
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    20. Michalska K, Steen AD, Chhor G, Endres M, Webber AT, Bird J, Lloyd KG, Joachimiak A. New aminopeptidase from "microbial dark matter" archaeon. FASEB J. 2015 Sep; 29(9):4071-9. PMID: 26062601.
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    21. Kim Y, Makowska-Grzyska M, Gorla SK, Gollapalli DR, Cuny GD, Joachimiak A, Hedstrom L. Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity. Acta Crystallogr F Struct Biol Commun. 2015 May; 71(Pt 5):531-8. PMID: 25945705.
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    22. Filippova EV, Kuhn ML, Osipiuk J, Kiryukhina O, Joachimiak A, Ballicora MA, Anderson WF. A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure. J Mol Biol. 2015 Mar 27; 427(6 Pt B):1316-1334. PMID: 25623305.
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    23. Makowska-Grzyska M, Kim Y, Maltseva N, Osipiuk J, Gu M, Zhang M, Mandapati K, Gollapalli DR, Gorla SK, Hedstrom L, Joachimiak A. A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity. J Biol Chem. 2015 Feb 27; 290(9):5893-911. PMID: 25572472.
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    24. Grabowska-Joachimiak A, Kula A, Ksiazczyk T, Chojnicka J, Sliwinska E, Joachimiak AJ. Chromosome landmarks and autosome-sex chromosome translocations in Rumex hastatulus, a plant with XX/XY1Y2 sex chromosome system. Chromosome Res. 2015 Jun; 23(2):187-97. PMID: 25394583.
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    25. Grabowska-Joachimiak A, Kula A, Gernand-Kliefoth D, Joachimiak AJ. Karyotype structure and chromosome fragility in the grass Phleum echinatum Host. Protoplasma. 2015 Jan; 252(1):301-6. PMID: 25056831.
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    26. Musial K, Koscinska-Pajak M, Antolec R, Joachimiak AJ. Deposition of callose in young ovules of two Taraxacum species varying in the mode of reproduction. Protoplasma. 2015 Jan; 252(1):135-44. PMID: 24938673.
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    27. Nocek B, Starus A, Makowska-Grzyska M, Gutierrez B, Sanchez S, Jedrzejczak R, Mack JC, Olsen KW, Joachimiak A, Holz RC. The dimerization domain in DapE enzymes is required for catalysis. PLoS One. 2014; 9(5):e93593. PMID: 24806882.
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    28. Makowska-Grzyska M, Kim Y, Maltseva N, Li H, Zhou M, Joachimiak G, Babnigg G, Joachimiak A. Protein production for structural genomics using E. coli expression. Methods Mol Biol. 2014; 1140:89-105. PMID: 24590711.
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    29. Binkowski TA, Jiang W, Roux B, Anderson WF, Joachimiak A. Virtual high-throughput ligand screening. Methods Mol Biol. 2014; 1140:251-61. PMID: 24590723.
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    30. Peruzzi L, Góralski G, Joachimiak AJ, Bedini G. Does actually mean chromosome number increase with latitude in vascular plants? An answer from the comparison of Italian, Slovak and Polish floras. Comp Cytogenet. 2012; 6(4):371-7. PMID: 24260677.
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    31. Tan K, Zhou M, Zhang R, Anderson WF, Joachimiak A. The crystal structures of the a-subunit of the a(2)ß (2) tetrameric Glycyl-tRNA synthetase. J Struct Funct Genomics. 2012 Dec; 13(4):233-9. PMID: 23054484.
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    32. Makowska-Grzyska M, Kim Y, Wu R, Wilton R, Gollapalli DR, Wang XK, Zhang R, Jedrzejczak R, Mack JC, Maltseva N, Mulligan R, Binkowski TA, Gornicki P, Kuhn ML, Anderson WF, Hedstrom L, Joachimiak A. Bacillus anthracis inosine 5'-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes. Biochemistry. 2012 Aug 07; 51(31):6148-63. PMID: 22788966.
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    33. Filippova EV, Brunzelle JS, Cuff ME, Li H, Joachimiak A, Anderson WF. Crystal structure of the novel PaiB transcriptional regulator from Geobacillus stearothermophilus. Proteins. 2011 Aug; 79(8):2578-82. PMID: 21633969.
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    34. Filippova EV, Shuvalova L, Minasov G, Kiryukhina O, Zhang Y, Clancy S, Radhakrishnan I, Joachimiak A, Anderson WF. Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production. Proteins. 2011 Aug; 79(8):2566-77. PMID: 21633970.
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    35. Kern J, Wilton R, Zhang R, Binkowski TA, Joachimiak A, Schneewind O. Structure of surface layer homology (SLH) domains from Bacillus anthracis surface array protein. J Biol Chem. 2011 Jul 22; 286(29):26042-9. PMID: 21572039.
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    36. Klos J, Sliwinska E, Kula A, Golczyk H, Grabowska-Joachimiak A, Ilnicki T, Szostek K, Stewart A, Joachimiak AJ. Karyotype and nuclear DNA content of hexa-, octo-, and duodecaploid lines of Bromus subgen. Ceratochloa. Genet Mol Biol. 2009 Jul; 32(3):528-37. PMID: 21637516.
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    37. Granovsky AE, Clark MC, McElheny D, Heil G, Hong J, Liu X, Kim Y, Joachimiak G, Joachimiak A, Koide S, Rosner MR. Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism. Mol Cell Biol. 2009 Mar; 29(5):1306-20. PMID: 19103740.
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    38. Richter S, Anderson VJ, Garufi G, Lu L, Budzik JM, Joachimiak A, He C, Schneewind O, Missiakas D. Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol. 2009 Jan; 71(2):404-20. PMID: 19017271.
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    39. Gillner DM, Bienvenue DL, Nocek BP, Joachimiak A, Zachary V, Bennett B, Holz RC. The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae contains two active-site histidine residues. J Biol Inorg Chem. 2009 Jan; 14(1):1-10. PMID: 18712420.
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    40. Qiu Y, Zhang R, Binkowski TA, Tereshko V, Joachimiak A, Kossiakoff A. The 1.38 A crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway. Proteins. 2008 May 01; 71(2):525-33. PMID: 18175314.
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    41. Maresso AW, Wu R, Kern JW, Zhang R, Janik D, Missiakas DM, Duban ME, Joachimiak A, Schneewind O. Activation of inhibitors by sortase triggers irreversible modification of the active site. J Biol Chem. 2007 Aug 10; 282(32):23129-39. PMID: 17545669.
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    42. Gernand D, Golczyk H, Rutten T, Ilnicki T, Houben A, Joachimiak AJ. Tissue culture triggers chromosome alterations, amplification, and transposition of repeat sequences in Allium fistulosum. Genome. 2007 May; 50(5):435-42. PMID: 17612612.
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    43. Gerdts CJ, Tereshko V, Yadav MK, Dementieva I, Collart F, Joachimiak A, Stevens RC, Kuhn P, Kossiakoff A, Ismagilov RF. Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization. Angew Chem Int Ed Engl. 2006 Dec 11; 45(48):8156-60. PMID: 17099920.
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    44. Shen Y, Joachimiak A, Rosner MR, Tang WJ. Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature. 2006 Oct 19; 443(7113):870-4. PMID: 17051221.
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    45. Qiu Y, Tereshko V, Kim Y, Zhang R, Collart F, Yousef M, Kossiakoff A, Joachimiak A. The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold. Proteins. 2006 Jan 01; 62(1):8-16. PMID: 16287087.
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    46. Binkowski TA, Joachimiak A, Liang J. Protein surface analysis for function annotation in high-throughput structural genomics pipeline. Protein Sci. 2005 Dec; 14(12):2972-81. PMID: 16322579.
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    47. Golczyk H, Hasterok R, Joachimiak AJ. FISH-aimed karyotyping and characterization of Renner complexes in permanent heterozygote Rhoeo spathacea. Genome. 2005 Feb; 48(1):145-53. PMID: 15729406.
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    48. Mosiolek M, Pasierbek P, Malarz J, Mos M, Joachimiak AJ. Rumex acetosa Y chromosomes: constitutive or facultative heterochromatin? Folia Histochem Cytobiol. 2005; 43(3):161-7. PMID: 16201317.
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    49. Williams WA, Zhang RG, Zhou M, Joachimiak G, Gornicki P, Missiakas D, Joachimiak A. The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions. Biochemistry. 2004 Dec 28; 43(51):16193-202. PMID: 15610013.
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    50. Brunzelle JS, Wu R, Korolev SV, Collart FR, Joachimiak A, Anderson WF. Crystal structure of Bacillus subtilis YdaF protein: a putative ribosomal N-acetyltransferase. Proteins. 2004 Dec 01; 57(4):850-3. PMID: 15468321.
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    51. Ruiz F, Hazemann I, Mitschler A, Joachimiak A, Schneider T, Karplus M, Podjarny A. The crystallographic structure of the aldose reductase-IDD552 complex shows direct proton donation from tyrosine 48. Acta Crystallogr D Biol Crystallogr. 2004 Aug; 60(Pt 8):1347-54. PMID: 15272156.
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    52. El-Kabbani O, Darmanin C, Schneider TR, Hazemann I, Ruiz F, Oka M, Joachimiak A, Schulze-Briese C, Tomizaki T, Mitschler A, Podjarny A. Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with Fidarestat and Minalrestat: implications for the binding of cyclic imide inhibitors. Proteins. 2004 Jun 01; 55(4):805-13. PMID: 15146479.
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    53. Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M. X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution. Biopolymers. 1998; 48(4):234-52. PMID: 10699842.
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    54. Otwinowski Z, Schevitz RW, Zhang RG, Lawson CL, Joachimiak A, Marmorstein RQ, Luisi BF, Sigler PB. Crystal structure of trp repressor/operator complex at atomic resolution. Nature. 1988 Sep 22; 335(6188):321-9. PMID: 3419502.
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    55. Lawson CL, Zhang RG, Schevitz RW, Otwinowski Z, Joachimiak A, Sigler PB. Flexibility of the DNA-binding domains of trp repressor. Proteins. 1988; 3(1):18-31. PMID: 3375234.
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