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Nicole Cipriani

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentPathology
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Cipriani is a surgical pathologist with a clinical subspecialty focus in Head & Neck, Thyroid, and Bone & Soft Tissue Pathology. Her diagnostic and research interests include neoplastic diseases of the thyroid gland, salivary glands, and upper aerodigestive tract. She also has an interest in Anatomic Pathologic Informatics, including web design, digital imaging, and virtual slides.

    Medical Director of Gross Pathology, The University of Chicago
    Director of Anatomic Pathology Informatics, The University of Chicago
    Treasurer, North American Society of Head & Neck Pathology


    Collapse Biography 
    Collapse education and training
    The University of Chicago, Chicago, ILAB06-2002Biological Sciences & Visual Arts
    The University of Illinois at Chicago, Chicago, ILMS05-2004Medical Illustration / Biomedical Visualization
    The University of Chicago Pritzker School of Medicine, Chicago, ILMD06-2008Medicine
    The University of Chicago, Chicago, ILResidency06-2012Anatomic & Clinical Pathology
    Massachusetts General Hospital, Boston, MAFellowship06-2013Head & Neck and Bone & Soft Tissue Pathology

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Wallace A, Liu P, Cipriani NA, Ginat D, Portugal L. Pituitary Adenoma Deposit in the Nasolabial Region Following Sublabial Transsphenoidal Surgery in the Setting of Nelson Syndrome. J Craniofac Surg. 2019 Oct 17. PMID: 31633667.
      View in: PubMed
    2. Cipriani NA. Prognostic Parameters in Differentiated Thyroid Carcinomas. Surg Pathol Clin. 2019 Dec; 12(4):883-900. PMID: 31672296.
      View in: PubMed
    3. Cracolici V, Judd R, Golden D, Cipriani NA. Art as a Learning Tool: Medical Student Perspectives on Implementing Visual Art into Histology Education. Cureus. 2019 Jul 23; 11(7):e5207. PMID: 31565612.
      View in: PubMed
    4. Cipriani NA, Lusardi JJ, McElherne J, Pearson AT, Olivas AD, Fitzpatrick C, Lingen MW, Blair EA. Mucoepidermoid Carcinoma: A Comparison of Histologic Grading Systems and Relationship to MAML2 Rearrangement and Prognosis. Am J Surg Pathol. 2019 Jul; 43(7):885-897. PMID: 31021855.
      View in: PubMed
    5. Cracolici V, Parilla M, Henriksen KJ, Cipriani NA. An Evaluation of CD61 Immunohistochemistry in Identification of Vascular Invasion in Follicular Thyroid Neoplasms. Head Neck Pathol. 2019 Jun 19. PMID: 31218593.
      View in: PubMed
    6. Cracolici V, Kadri S, Ritterhouse LL, Segal JP, Wanjari P, Cipriani NA. Clinicopathologic and Molecular Features of Metastatic Follicular Thyroid Carcinoma in Patients Presenting With a Thyroid Nodule Versus a Distant Metastasis. Am J Surg Pathol. 2019 Apr; 43(4):514-522. PMID: 30557173.
      View in: PubMed
    7. Banach BS, Antic T, Bridge JA, Cipriani NA, Frye L, Krausz TN, Biernacka A. Fine-needle aspiration of dermatofibrosarcoma protuberans metastasizing to hemithorax with superior vena cava compression: Case report and literature review. Diagn Cytopathol. 2019 Aug; 47(8):797-802. PMID: 30919592.
      View in: PubMed
    8. Johnson DN, Cavallo AB, Uraizee I, Tanager K, Lastra RR, Antic T, Cipriani NA. A Proposal for Separation of Nuclear Atypia and Architectural Atypia in Bethesda Category III (AUS/FLUS) Based on Differing Rates of Thyroid Malignancy. Am J Clin Pathol. 2019 01 01; 151(1):86-94. PMID: 30212867.
      View in: PubMed
    9. Scherpelz KP, Wong AC, Lingen MW, Taxy JB, Cipriani NA. Histological features and prognostic significance of treatment effect in lymph node metastasis in head and neck squamous cell carcinoma. Histopathology. 2019 Jan; 74(2):321-331. PMID: 30144145.
      View in: PubMed
    10. Williams EA, Moy AP, Cipriani NA, Nigwekar SU, Nazarian RM. Factors associated with false-negative pathologic diagnosis of calciphylaxis. J Cutan Pathol. 2019 Jan; 46(1):16-25. PMID: 30280393.
      View in: PubMed
    11. Cipriani NA, White MG, Angelos P, Grogan RH. Large Cytologically Benign Thyroid Nodules Do Not Have High Rates of Malignancy or False-Negative Rates and Clinical Observation Should be Considered: A Meta-Analysis. Thyroid. 2018 Oct 30. PMID: 30280990.
      View in: PubMed
    12. McMullen PD, Bridge JA, Blair EA, Yang CW, Collins J, Cipriani NA. Aneurysmal Bone Cyst of the Maxillary Sinus with USP6 Rearrangement: Case Report of a Rare Entity and Review of the Literature. Head Neck Pathol. 2019 Sep; 13(3):281-285. PMID: 30076509.
      View in: PubMed
    13. Fidai SS, Cipriani NA, Ginat DT. Histiocytic Necrotizing Lymphadenitis Involving the Neck: Radiology-Pathology Correlation. Head Neck Pathol. 2019 Dec; 13(4):648-651. PMID: 29858834.
      View in: PubMed
    14. Ginat DT, Cipriani NA, Christoforidis G. Educational Impact of Trainee-Facilitated Head and Neck Radiology-Pathology Correlation Conferences. Head Neck Pathol. 2019 Jun; 13(2):177-181. PMID: 29774485.
      View in: PubMed
    15. Ginat D, Schulte J, Gooi Z, Cipriani N. High-Grade Conventional Osteosarcoma of the Mandible Associated With P53 Germline Mutation. J Craniofac Surg. 2018 May; 29(3):738-740. PMID: 29420387.
      View in: PubMed
    16. Johnson DN, Furtado LV, Long BC, Zhen CJ, Wurst M, Mujacic I, Kadri S, Segal JP, Antic T, Cipriani NA. Noninvasive Follicular Thyroid Neoplasms With Papillary-like Nuclear Features Are Genetically and Biologically Similar to Adenomatous Nodules and Distinct From Papillary Thyroid Carcinomas With Extensive Follicular Growth. Arch Pathol Lab Med. 2018 07; 142(7):838-850. PMID: 29582677.
      View in: PubMed
    17. Cracolici V, Krausz T, Cipriani NA. Ubiquitin Immunostaining in Thyroid Neoplasms Marks True Intranuclear Cytoplasmic Pseudoinclusions and May Help Differentiate Papillary Carcinoma from NIFTP. Head Neck Pathol. 2018 Dec; 12(4):522-528. PMID: 29512025.
      View in: PubMed
    18. Cracolici V, Mujacic I, Kadri S, Alikhan M, Niu N, Segal JP, Rosen LE, Sarne DH, Morgan A, Desouky S, Cipriani NA. Synchronous and Metastatic Papillary and Follicular Thyroid Carcinomas with Unique Molecular Signatures. Endocr Pathol. 2018 Mar; 29(1):9-14. PMID: 28710706.
      View in: PubMed
    19. Yesensky JA, Hasina R, Wroblewski KE, Bellairs J, Gooi Z, Saloura V, Cipriani NA, Vokes EE, Portugal LG, Seiwert TY, Blair ED, Agrawal N. Role of dental hardware in oral cavity squamous cell carcinoma in the low-risk nonsmoker nondrinker population. Head Neck. 2018 04; 40(4):784-792. PMID: 29356169.
      View in: PubMed
    20. Cracolici V, Grogan RH, Sukhanova M, Cheng JX, Gurbuxani S, Cipriani NA. A Herald of Plasma Cell Myeloma: A Report of Malignant Plasma Cells Identified in Parathyroid Adenoma and a Review of Non-parathyroid Malignancies in Parathyroid Glands. Head Neck Pathol. 2018 Jun; 12(2):286-290. PMID: 29030756.
      View in: PubMed
    21. Uraizee I, Cipriani NA, Ginat DT. Adenoid Cystic Carcinoma of the Oral Cavity: Radiology-Pathology Correlation. Head Neck Pathol. 2018 Dec; 12(4):562-566. PMID: 28879643.
      View in: PubMed
    22. Ginat DT, Johnson DN, Shogan A, Cipriani NA. Cervical Chondrocutaneous Branchial Remnants. Head Neck Pathol. 2018 Jun; 12(2):244-246. PMID: 28685414.
      View in: PubMed
    23. Can NT, Lingen MW, Mashek H, McElherne J, Briese R, Fitzpatrick C, van Zante A, Cipriani NA. Expression of Hormone Receptors and HER-2 in Benign and Malignant Salivary Gland Tumors. Head Neck Pathol. 2018 Mar; 12(1):95-104. PMID: 28681314.
      View in: PubMed
    24. Shelton J, Purgina BM, Cipriani NA, Dupont WD, Plummer D, Lewis JS. p16 immunohistochemistry in oropharyngeal squamous cell carcinoma: a comparison of antibody clones using patient outcomes and high-risk human papillomavirus RNA status. Mod Pathol. 2017 09; 30(9):1194-1203. PMID: 28621317.
      View in: PubMed
    25. Ginat DT, Schulte J, Portugal L, Cipriani NA. Laryngotracheal Involvement in Systemic Light Chain Amyloidosis. Head Neck Pathol. 2018 Mar; 12(1):127-130. PMID: 28616786.
      View in: PubMed
    26. Bawa HS, Moore DD, Pelayo JC, Cipriani N, Mak G, Haydon RC. Pediatric Chondrosarcoma of the Sternum Resected with Thorascopic Assistance. Open Orthop J. 2017; 11:479-485. PMID: 28694886.
      View in: PubMed
    27. Cipriani NA, Blair EA, Finkle J, Kraninger JL, Straus CM, Villaflor VM, Ginat DT. Salivary Gland Secretory Carcinoma With High-Grade Transformation, CDKN2A/B Loss, Distant Metastasis, and Lack of Sustained Response to Crizotinib. Int J Surg Pathol. 2017 Oct; 25(7):613-618. PMID: 28497708.
      View in: PubMed
    28. Saloura V, Fatima A, Zewde M, Kiyotani K, Brisson R, Park JH, Ikeda Y, Vougiouklakis T, Bao R, Khattri A, Seiwert T, Cipriani N, Lingen M, Vokes E, Nakamura Y. Characterization of the T-Cell Receptor Repertoire and Immune Microenvironment in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res. 2017 Aug 15; 23(16):4897-4907. PMID: 28442504.
      View in: PubMed
    29. Cipriani NA, Agarwal S, Dias-Santagata D, Faquin WC, Sadow PM. Clear Cell Change in Thyroid Carcinoma: A Clinicopathologic and Molecular Study with Identification of Variable Genetic Anomalies. Thyroid. 2017 06; 27(6):819-824. PMID: 28293986.
      View in: PubMed
    30. Hellquist H, French CA, Bishop JA, Coca-Pelaz A, Propst EJ, Paiva Correia A, Ngan BY, Grant R, Cipriani NA, Vokes D, Henrique R, Pardal F, Vizcaino JR, Rinaldo A, Ferlito A. NUT midline carcinoma of the larynx: an international series and review of the literature. Histopathology. 2017 May; 70(6):861-868. PMID: 27926786.
      View in: PubMed
    31. Cavallo A, Johnson DN, White MG, Siddiqui S, Antic T, Mathew M, Grogan RH, Angelos P, Kaplan EL, Cipriani NA. Thyroid Nodule Size at Ultrasound as a Predictor of Malignancy and Final Pathologic Size. Thyroid. 2017 05; 27(5):641-650. PMID: 28052718.
      View in: PubMed
    32. Choy B, Hyjek E, Montag AG, Pytel P, Haydon R, Luu HH, Zhen CJ, Long BC, Kadri S, Segal JP, Furtado LV, Cipriani NA. High prevalence of MiTF staining in undifferentiated pleomorphic sarcoma: caution in the use of melanocytic markers in sarcoma. Histopathology. 2017 Apr; 70(5):734-745. PMID: 27926791.
      View in: PubMed
    33. Ginat DT, Cipriani NA, Purakal A, Fitzpatrick C, Paral K, Krausz T, Pytel P. Disseminated Malignant Rhabdoid Tumor of the Head and Neck. Head Neck Pathol. 2017 Jun; 11(2):224-227. PMID: 27632188.
      View in: PubMed
    34. White MG, Cipriani NA, Abdulrasool L, Kaplan S, Aschebrook-Kilfoy B, Angelos P, Kaplan EL, Grogan RH, Onel K. Radiation-Induced Differentiated Thyroid Cancer Is Associated with Improved Overall Survival but Not Thyroid Cancer-Specific Mortality or Disease-Free Survival. Thyroid. 2016 08; 26(8):1053-60. PMID: 27279587.
      View in: PubMed
    35. Montague G, Cipriani N, Naclerio RM. A Rapidly Enlarging Forehead Mass in a Young Retinoblastoma Survivor. JAMA Otolaryngol Head Neck Surg. 2016 06 01; 142(6):597-8. PMID: 26967745.
      View in: PubMed
    36. Siddiqui S, White MG, Antic T, Grogan RH, Angelos P, Kaplan EL, Cipriani NA. Clinical and Pathologic Predictors of Lymph Node Metastasis and Recurrence in Papillary Thyroid Microcarcinoma. Thyroid. 2016 06; 26(6):807-15. PMID: 27117842.
      View in: PubMed
    37. Al-Saraf A, Yassan L, Cipriani NA, Agrawal N, Chang P, Ginat DT. Desmoid-Type Fibromatosis of the Tongue. Head Neck Pathol. 2016 Dec; 10(4):527-529. PMID: 27091208.
      View in: PubMed
    38. James BC, Aschebrook-Kilfoy B, Cipriani N, Kaplan EL, Angelos P, Grogan RH. The Incidence and Survival of Rare Cancers of the Thyroid, Parathyroid, Adrenal, and Pancreas. Ann Surg Oncol. 2016 Feb; 23(2):424-33. PMID: 26467460.
      View in: PubMed
    39. Partridge JC, Cipriani N, Faquin WC, Chuang SK, Keith DA, Lahey ET. Periarticular Cysts of the Temporomandibular Joint Are More Frequently Synovial Than Ganglion. J Oral Maxillofac Surg. 2016 Jul; 74(7):1396-402. PMID: 26902711.
      View in: PubMed
    40. Fidai SS, Ginat DT, Langerman AJ, Cipriani NA. Dedifferentiated Chondrosarcoma of the Larynx. Head Neck Pathol. 2016 Sep; 10(3):345-8. PMID: 26718693.
      View in: PubMed
    41. Karim SM, Colman MC, Cipriani NA, Nielsen GP, Schwab JH, Hornicek FJ. Surgical management of Gorham-Stout disease of the pelvis refractory to medical and radiation therapy. Am J Orthop (Belle Mead NJ). 2015 Nov; 44(11):E473-7. PMID: 26566566.
      View in: PubMed
    42. Cipriani NA, Nagar S, Kaplan SP, White MG, Antic T, Sadow PM, Aschebrook-Kilfoy B, Angelos P, Kaplan EL, Grogan RH. Follicular Thyroid Carcinoma: How Have Histologic Diagnoses Changed in the Last Half-Century and What Are the Prognostic Implications? Thyroid. 2015 Nov; 25(11):1209-16. PMID: 26440366.
      View in: PubMed
    43. Lennon FE, Cianci GC, Cipriani NA, Hensing TA, Zhang HJ, Chen CT, Murgu SD, Vokes EE, Vannier MW, Salgia R. Lung cancer-a fractal viewpoint. Nat Rev Clin Oncol. 2015 Nov; 12(11):664-75. PMID: 26169924.
      View in: PubMed
    44. Ginat DT, Villaflor V, Cipriani NA. Oral Cavity Clear Cell Odontogenic Carcinoma. Head Neck Pathol. 2016 Jun; 10(2):217-20. PMID: 25994920.
      View in: PubMed
    45. Ginat DT, Johnson DN, Cipriani NA. Langerhans Cell Histiocytosis of the Temporal Bone. Head Neck Pathol. 2016 Jun; 10(2):209-12. PMID: 25903273.
      View in: PubMed
    46. Cipriani NA, Pytel P, Grogan RH. Oncocytic adenoma in a black thyroid. Int J Surg Pathol. 2014 Oct; 22(7):629-30. PMID: 24942895.
      View in: PubMed
    47. Cipriani NA, Kurzawa P, Ahmad RA, Deshpande V, Hornicek FJ, Mullen JT, Nielsen GP. Prognostic value of myogenic differentiation in undifferentiated pleomorphic sarcomas of soft tissue. Hum Pathol. 2014 Jul; 45(7):1504-8. PMID: 24780826.
      View in: PubMed
    48. Cipriani NA, Letovanec I, Hornicek FJ, Mullen JT, Duan Z, Borger DR, Nielsen GP. BRAF mutation in 'sarcomas': a possible method to detect de-differentiated melanomas. Histopathology. 2014 Apr; 64(5):639-46. PMID: 24117833.
      View in: PubMed
    49. Cipriani NA, Ryan DP, Nielsen GP. Primitive myxoid mesenchymal tumor of infancy with rosettes: a new finding and literature review. Int J Surg Pathol. 2014 Oct; 22(7):647-51. PMID: 24240695.
      View in: PubMed
    50. Cipriani NA, Strek M, Noth I, Gordon IO, Charbeneau J, Krishnan JA, Krausz T, Husain AN. Pathologic quantification of connective tissue disease-associated versus idiopathic usual interstitial pneumonia. Arch Pathol Lab Med. 2012 Oct; 136(10):1253-8. PMID: 23020731.
      View in: PubMed
    51. Cipriani NA, Martin DE, Corey JP, Portugal L, Caballero N, Lester R, Anthony B, Taxy JB. The clinicopathologic spectrum of benign mass lesions of the vocal fold due to vocal abuse. Int J Surg Pathol. 2011 Oct; 19(5):583-7. PMID: 21685134.
      View in: PubMed
    52. Zoccali M, Cipriani N, Fichera A, Turner JR, Krane M. Acute appendicitis secondary to a granular cell tumor of the appendix in a 19-year-old male. J Gastrointest Surg. 2011 Aug; 15(8):1482-5. PMID: 21533589.
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    53. Gwin K, Cipriani N, Zhang X, Schmidt R, Hyjek E. Bilateral breast involvement by disseminated extranodal Rosai-Dorfman disease. Breast J. 2011 May-Jun; 17(3):309-11. PMID: 21450017.
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    54. Archer SL, Marsboom G, Kim GH, Zhang HJ, Toth PT, Svensson EC, Dyck JR, Gomberg-Maitland M, Th├ębaud B, Husain AN, Cipriani N, Rehman J. Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. Circulation. 2010 Jun 22; 121(24):2661-71. PMID: 20529999.
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    55. Cipriani NA, Blair E, Taxy JB. WHIM syndrome and oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jan; 109(1):105-8. PMID: 19926501.
      View in: PubMed
    56. Cipriani NA, Hong C, Rosenblum J, Pytel P. Air embolism with pneumocephalus. Arch Neurol. 2009 Sep; 66(9):1172-3. PMID: 19752312.
      View in: PubMed
    57. Gordon IO, Cipriani N, Arif Q, Mackinnon AC, Husain AN. Update in nonneoplastic lung diseases. Arch Pathol Lab Med. 2009 Jul; 133(7):1096-105. PMID: 19642736.
      View in: PubMed
    58. Clayburgh DR, Yoon JD, Cipriani NA, Ricketts PA, Arora VM. Clinical problem-solving. Collateral damage. N Engl J Med. 2008 Sep 04; 359(10):1048-54. PMID: 18768949.
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    59. Cipriani NA, Abidoye OO, Vokes E, Salgia R. MET as a target for treatment of chest tumors. Lung Cancer. 2009 Feb; 63(2):169-79. PMID: 18672314.
      View in: PubMed
    60. Tseng CY, Lang PO, Cipriani NA, Song DH. Pedicle preservation technique for arterial and venous turbocharging of free DIEP and muscle-sparing TRAM flaps. Plast Reconstr Surg. 2007 Sep 15; 120(4):851-4. PMID: 17805111.
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    61. Dachman AH, Dawson DO, Lefere P, Yoshida H, Khan NU, Cipriani N, Rubin DT. Comparison of routine and unprepped CT colonography augmented by low fiber diet and stool tagging: a pilot study. Abdom Imaging. 2007 Jan-Feb; 32(1):96-104. PMID: 16969601.
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    62. Yitta S, Tatineny KC, Cipriani NA, Dachman AH. Characterization of normal ileocecal valve density on CT colonography. J Comput Assist Tomogr. 2006 Jan-Feb; 30(1):58-61. PMID: 16365573.
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