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Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
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Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation. Arterioscler Thromb Vasc Biol. 2013 Jul; 33(7):1591-600.
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PubMed
subject areas
Adaptor Proteins, Signal Transducing
Angiotensin II
Animals
Biomarkers
Cardiomegaly
Cells, Cultured
Cholesterol
Cholesterol, LDL
Coronary Vessels
Cross-Over Studies
Cytoskeletal Proteins
Disease Models, Animal
Dose-Response Relationship, Drug
Fibrosis
Glycogen Synthase Kinase 3
Glycogen Synthase Kinase 3 beta
Guanine Nucleotide Exchange Factors
Heptanoic Acids
Human Umbilical Vein Endothelial Cells
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Japan
Male
Mice
Mice, Knockout
Neuropeptides
Oxidative Stress
Phosphatidylinositol 3-Kinase
Pravastatin
Proto-Oncogene Proteins c-akt
Pyrroles
Quinolines
rac GTP-Binding Proteins
rac1 GTP-Binding Protein
RNA Interference
Signal Transduction
Transfection
authors with profiles
James Liao