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The TGFß-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors.
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The TGFß-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors.
The TGFß-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors. Cancer Res. 2014 Jul 15; 74(14):3995-4005.
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PubMed
subject areas
Adaptor Proteins, Signal Transducing
Animals
Antineoplastic Agents
Cell Line, Tumor
Disease Models, Animal
Drug Resistance, Neoplasm
Enzyme Activation
Epithelial-Mesenchymal Transition
ErbB Receptors
Gene Expression Regulation, Neoplastic
Humans
Lung Neoplasms
Mice
MicroRNAs
Organ Specificity
Pancreatic Neoplasms
Phenotype
Protein Kinase Inhibitors
Proto-Oncogene Proteins c-akt
Signal Transduction
Transforming Growth Factor beta
Tumor Suppressor Proteins
Xenograft Model Antitumor Assays
authors with profiles
Evgeny Izumchenko