"HMGA2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An AT-hook-containing (AT-HOOK MOTIFS) nuclear protein that is expressed predominantly in proliferating and undifferentiated mesenchymal cells.
| Descriptor ID |
D025743
|
| MeSH Number(s) |
D12.776.260.312.937 D12.776.660.235.400.500.600 D12.776.664.235.400.500.600
|
| Concept/Terms |
HMGA2 Protein- HMGA2 Protein
- HMGI-C Protein
- HMGI C Protein
- HMG I-C Protein
- HMG I C Protein
|
Below are MeSH descriptors whose meaning is more general than "HMGA2 Protein".
Below are MeSH descriptors whose meaning is more specific than "HMGA2 Protein".
This graph shows the total number of publications written about "HMGA2 Protein" by people in this website by year, and whether "HMGA2 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 2 | 1 | 3 |
| 2013 | 3 | 0 | 3 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "HMGA2 Protein" by people in Profiles.
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Progenitor cell diversity in the developing mouse neocortex. Proc Natl Acad Sci U S A. 2021 03 09; 118(10).
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Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target. Nat Commun. 2020 07 03; 11(1):3303.
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H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas. Oncogene. 2019 07; 38(27):5356-5366.
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Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages. Cancer Res. 2015 Oct 01; 75(19):4063-73.
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RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2. Oncogene. 2014 Jul 03; 33(27):3528-37.
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HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9920-5.
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WNT10B/ß-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer. EMBO Mol Med. 2013 Feb; 5(2):264-79.
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HMGA2 levels in CML: reflective of miRNA gene regulation in a hematopoietic tumor? Leuk Lymphoma. 2007 Oct; 48(10):1898-9.
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Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2. Cell Cycle. 2007 Nov 01; 6(21):2585-90.
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Let-7 expression defines two differentiation stages of cancer. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11400-5.