"Myeloblastin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.
| Descriptor ID |
D053146
|
| MeSH Number(s) |
D08.811.277.656.300.760.530 D08.811.277.656.959.350.530
|
| Concept/Terms |
Myeloblastin- Myeloblastin
- Leukocyte Proteinase 3
- Proteinase 3, Leukocyte
- Myeloblastin, Human
- Human Myeloblastin
- N-Proteinase 4
- N Proteinase 4
- PRTN3 Gene Protein
- Protein, PRTN3 Gene
- Neutrophil Proteinase 3, Human
- Neutrophil Proteinase 4
- Proteinase 4, Neutrophil
- Proteinase 3
- Wegener Autoantigen
- Autoantigen, Wegener
- C-ANCA Antigen
- Antigen, C-ANCA
- C ANCA Antigen
- Azurophil Granule Protein 7
- Neutrophil Proteinase 3
- Proteinase 3, Neutrophil
|
Below are MeSH descriptors whose meaning is more general than "Myeloblastin".
Below are MeSH descriptors whose meaning is more specific than "Myeloblastin".
This graph shows the total number of publications written about "Myeloblastin" by people in this website by year, and whether "Myeloblastin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myeloblastin" by people in Profiles.
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Prevalence and Clinical Significance of Antineutrophil Cytoplasmic Antibodies in North American Patients With Idiopathic Pulmonary Fibrosis. Chest. 2019 10; 156(4):715-723.
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A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury. Crit Care Med. 2015 Aug; 43(8):1646-53.
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Identification of constituents of human neutrophil azurophil granules that mediate fungistasis against Histoplasma capsulatum. Infect Immun. 2000 Oct; 68(10):5668-72.
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Antimicrobial proteins with homology to serine proteases. Ciba Found Symp. 1994; 186:237-47; discussion 247-9.
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Antibiotic peptides and serine protease homologs in human polymorphonuclear leukocytes: defensins and azurocidin. Curr Opin Immunol. 1993 Feb; 5(1):97-102.
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Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils. J Exp Med. 1990 Dec 01; 172(6):1709-15.