"Pancreatic Elastase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protease of broad specificity, obtained from dried pancreas. Molecular weight is approximately 25,000. The enzyme breaks down elastin, the specific protein of elastic fibers, and digests other proteins such as fibrin, hemoglobin, and albumin. EC 3.4.21.36.
| Descriptor ID |
D010196
|
| MeSH Number(s) |
D08.811.277.656.300.760.560 D08.811.277.656.959.350.560
|
| Concept/Terms |
Pancreatic Elastase- Pancreatic Elastase
- Elastase, Pancreatic
- Pancreatic Elastase I
- Elastase I, Pancreatic
- Elastase
- Pancreatopeptidase
|
Below are MeSH descriptors whose meaning is more general than "Pancreatic Elastase".
Below are MeSH descriptors whose meaning is more specific than "Pancreatic Elastase".
This graph shows the total number of publications written about "Pancreatic Elastase" by people in this website by year, and whether "Pancreatic Elastase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Pancreatic Elastase" by people in Profiles.
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Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency. Chest. 2021 10; 160(4):1442-1458.
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Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis. Cell. 2021 06 10; 184(12):3163-3177.e21.
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Pancreatic Malnutrition in Children. Pediatr Ann. 2019 Nov 01; 48(11):e441-e447.
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Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma. J Clin Invest. 2019 08 01; 129(11):4676-4681.
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American Pancreatic Association Practice Guidelines in Chronic Pancreatitis: evidence-based report on diagnostic guidelines. Pancreas. 2014 Nov; 43(8):1143-62.
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Invited commentary. J Vasc Surg. 2014 Aug; 60(2):461.
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Therapeutic targets in pulmonary arterial hypertension. Pharmacol Ther. 2009 Jan; 121(1):69-88.
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Elements in the C terminus of apolipoprotein [a] responsible for the binding to the tenth type III module of human fibronectin. J Lipid Res. 2005 Dec; 46(12):2673-80.
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Caspases from apoptotic myocytes degrade extracellular matrix: a novel remodeling paradigm. FASEB J. 2005 Nov; 19(13):1848-50.
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Randomized, double-blind, placebo-controlled, dose-escalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease. Pediatr Pulmonol. 2005 Mar; 39(3):209-18.