"Lactoferrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the TYPE III SECRETION SYSTEM used by bacteria to export virulence proteins for host cell invasion.
| Descriptor ID |
D007781
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| MeSH Number(s) |
D08.811.277.656.300.760.471 D08.811.277.656.959.350.471 D12.776.157.427.750.249 D12.776.256.626.816.500.507 D12.776.377.457.507 D12.776.395.507 D12.776.556.579.750.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lactoferrin".
Below are MeSH descriptors whose meaning is more specific than "Lactoferrin".
This graph shows the total number of publications written about "Lactoferrin" by people in this website by year, and whether "Lactoferrin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lactoferrin" by people in Profiles.
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Multiplex immunoassay of lower genital tract mucosal fluid from women attending an urban STD clinic shows broadly increased IL1ß and lactoferrin. PLoS One. 2011 May 10; 6(5):e19560.
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Phase 2 trial of talactoferrin in previously treated patients with metastatic renal cell carcinoma. Cancer. 2008 Jul 01; 113(1):72-7.
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Changes in salivary proteome following allogeneic hematopoietic stem cell transplantation. Exp Hematol. 2007 Feb; 35(2):184-92.
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Neutrophil granule products: can they identify subclinical chorioamnionitis in patients with preterm premature rupture of membranes? Am J Obstet Gynecol. 2003 Sep; 189(3):808-12.
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Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation. Am J Gastroenterol. 2003 Jun; 98(6):1309-14.
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Platelet and leukocyte activation and design consequences for thoracic artificial lungs. ASAIO J. 2002 Nov-Dec; 48(6):620-30.
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Surface expression of lactoferrin by resting neutrophils. Biochem Biophys Res Commun. 2000 Aug 18; 275(1):241-6.
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Comparison of nasal mucosal responsiveness to neuronal stimulation in non-allergic and allergic rhinitis: effects of capsaicin nasal challenge. Clin Exp Allergy. 1998 Jan; 28(1):92-100.
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Treatment with hot, humid air reduces the nasal response to allergen challenge. J Allergy Clin Immunol. 1997 Jan; 99(1 Pt 1):77-86.
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The human nasal response to capsaicin. J Allergy Clin Immunol. 1994 Dec; 94(6 Pt 1):1035-45.