AlkB Homolog 8, tRNA Methyltransferase
"AlkB Homolog 8, tRNA Methyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dioxygenase and alkylation repair homolog that catalyzes the methylation of 5-carboxymethyl URIDINE to 5-methylcarboxymethyl uridine at the wobble position of the ANTICODON loop in TRANSFER RNA (tRNA) via its methyltransferase domain. It has a preference for tRNA (ARGININE) and tRNA (GLUTAMATE), and does not bind tRNA (LYSINE).
| Descriptor ID |
D000071503
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| MeSH Number(s) |
D08.811.682.690.416.139.984 D08.811.913.555.500.925.500
|
| Concept/Terms |
AlkB Homolog 8, tRNA Methyltransferase- AlkB Homolog 8, tRNA Methyltransferase
- Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH8
- Probable Alpha Ketoglutarate Dependent Dioxygenase ABH8
- tRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH8
- Alkylated DNA Repair Protein Alkb Homolog 8
- S-Adenosyl-L-Methionine-Dependent tRNA Methyltransferase ABH8
- S Adenosyl L Methionine Dependent tRNA Methyltransferase ABH8
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Below are MeSH descriptors whose meaning is more general than "AlkB Homolog 8, tRNA Methyltransferase".
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This graph shows the total number of publications written about "AlkB Homolog 8, tRNA Methyltransferase" by people in this website by year, and whether "AlkB Homolog 8, tRNA Methyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "AlkB Homolog 8, tRNA Methyltransferase" by people in Profiles.
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The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. Angew Chem Int Ed Engl. 2010 Nov 15; 49(47):8885-8.