"Smad6 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitory Smad protein that negatively regulates the SIGNAL TRANSDUCTION PATHWAYS from BONE MORPHOGENETIC PROTEIN RECEPTORS. Smad6 inhibits PHOSPHORYLATION of SMAD2 PROTEIN and SMAD3 PROTEIN.
| Descriptor ID |
D051905
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| MeSH Number(s) |
D12.644.360.024.334.200.600 D12.776.157.057.170.249.600 D12.776.476.024.428.249.600 D12.776.930.806.875
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Smad6 Protein".
Below are MeSH descriptors whose meaning is more specific than "Smad6 Protein".
This graph shows the total number of publications written about "Smad6 Protein" by people in this website by year, and whether "Smad6 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Smad6 Protein" by people in Profiles.
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Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-ß and Cardiac Fibrosis. Circulation. 2017 Aug 15; 136(7):664-679.
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Bone mesenchymal stem cell-conditioned medium induces the upregulation of Smad6, which inhibits the BMP-4/Smad1/5/8 signaling pathway. Neurol Res. 2016 Nov; 38(11):965-972.
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Transforming growth factor-beta stimulates epithelial-mesenchymal transformation in the proepicardium. Dev Dyn. 2006 Jan; 235(1):50-9.