"Demethylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Removal of one or more methyl groups from a chemical compound.
| Descriptor ID |
D000073398
|
| MeSH Number(s) |
G02.111.188.500 G02.607.141.500 G03.219.500
|
| Concept/Terms |
Oxidative Demethylation- Oxidative Demethylation
- Demethylation, Oxidative
- Demethylations, Oxidative
- Oxidative Demethylations
|
Below are MeSH descriptors whose meaning is more general than "Demethylation".
Below are MeSH descriptors whose meaning is more specific than "Demethylation".
This graph shows the total number of publications written about "Demethylation" by people in this website by year, and whether "Demethylation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Demethylation" by people in Profiles.
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Evi1 governs Kdm6b-mediated histone demethylation to regulate the Laptm4b-driven mTOR pathway in hematopoietic progenitor cells. J Clin Invest. 2024 Dec 16; 134(24).
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The Molecular Basis of Human ALKBH3 Mediated RNA N1 -methyladenosine (m1 A) Demethylation. Angew Chem Int Ed Engl. 2024 02 12; 63(7):e202313900.
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Iron drives anabolic metabolism through active histone demethylation and mTORC1. Nat Cell Biol. 2023 Oct; 25(10):1478-1494.
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Demethylation of dimethyl phosphonate esters with sodium ethanethiolate: Improved synthesis of 5'-methylene substituted 2',5'-deoxyribonucleotides. Nucleosides Nucleotides Nucleic Acids. 2023; 42(7):538-546.
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FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 05 27; 376(6596):968-973.
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m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782.
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Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell. 2018 09 20; 71(6):973-985.e5.
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Selective Enzymatic Demethylation of N2 ,N2 -Dimethylguanosine in RNA and Its Application in High-Throughput tRNA Sequencing. Angew Chem Int Ed Engl. 2017 04 24; 56(18):5017-5020.