"Receptors, Somatomedin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors that bind somatomedins and trigger intracellular changes which influence the behavior of cells. Studies have disclosed two types of receptors for this family of peptide hormones. The type I receptor is homologous to the insulin receptor and has tyrosine kinase activity. The type II receptor is identical to the mannose-6-phosphate receptor which is important in trafficking of lysosomal enzymes.
| Descriptor ID |
D017451
|
| MeSH Number(s) |
D12.776.543.750.750.400.780
|
| Concept/Terms |
Receptors, Somatomedin- Receptors, Somatomedin
- Insulin-Like Growth Factor Receptors
- Insulin Like Growth Factor Receptors
- Somatomedin Receptor
- Receptor, Somatomedin
- Somatomedin Receptors
- Insulin-Like Growth Factor Receptor
- Insulin Like Growth Factor Receptor
- Receptors, Insulin-Like Growth Factors
- Receptors, Insulin Like Growth Factors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Somatomedin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatomedin".
This graph shows the total number of publications written about "Receptors, Somatomedin" by people in this website by year, and whether "Receptors, Somatomedin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Somatomedin" by people in Profiles.
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Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression. J Natl Cancer Inst. 2016 10; 108(10).
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An insulin-like growth factor I/insulin hybrid exhibiting high potency for interaction with the type I insulin-like growth factor and insulin receptors of placental plasma membranes. J Biol Chem. 1990 Oct 15; 265(29):17820-5.
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Insulin-like growth factor I and insulin potentiate luteinizing hormone-induced androgen synthesis by rat ovarian thecal-interstitial cells. Endocrinology. 1988 Aug; 123(2):733-9.