"Receptor, IGF Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor that is specific for IGF-II and mannose-6-phosphate. The receptor is a 250-kDa single chain polypeptide which is unrelated in structure to the type 1 IGF receptor (RECEPTOR, IGF TYPE 1) and does not have a tyrosine kinase domain.
| Descriptor ID |
D017527
|
| MeSH Number(s) |
D12.776.543.750.750.400.780.410
|
| Concept/Terms |
Receptor, IGF Type 2- Receptor, IGF Type 2
- IGF-2 Receptor
- IGF 2 Receptor
- Receptor, IGF-2
- IGF-II Receptor
- IGF II Receptor
- Insulin-Like-Growth-Factor II Receptor
- Insulin Like Growth Factor II Receptor
- Receptor, Insulin-Like-Growth-Factor II
- Mannose-6-Phosphate Receptor
- Mannose 6 Phosphate Receptor
- Receptor, Insulin-Like Growth Factor II
- Receptor, Insulin Like Growth Factor II
- Receptor, Insulin-Like Growth Factor Type 2
- Receptor, Insulin Like Growth Factor Type 2
- Receptor, Mannose-6-Phosphate
- Receptor, Mannose 6 Phosphate
- Receptors, IGF-2
- IGF-2 Receptors
- Receptors, IGF 2
- Receptors, Insulin-Like Growth Factor II
- Receptors, Insulin Like Growth Factor II
- IGF Type 2 Receptor
- Receptor, IGF-II
- Receptor, IGF II
|
Below are MeSH descriptors whose meaning is more general than "Receptor, IGF Type 2".
Below are MeSH descriptors whose meaning is more specific than "Receptor, IGF Type 2".
This graph shows the total number of publications written about "Receptor, IGF Type 2" by people in this website by year, and whether "Receptor, IGF Type 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, IGF Type 2" by people in Profiles.
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Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases. Mol Neurobiol. 2017 05; 54(4):2636-2658.
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Overexpression of the Insulin-Like Growth Factor II Receptor Increases ß-Amyloid Production and Affects Cell Viability. Mol Cell Biol. 2015 Jul; 35(14):2368-84.
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Overexpression of the IGF-II/M6P receptor in mouse fibroblast cell lines differentially alters expression profiles of genes involved in Alzheimer's disease-related pathology. PLoS One. 2014; 9(5):e98057.
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High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet. 2008 Feb 15; 17(4):617-27.
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Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells. J Biol Chem. 2004 May 07; 279(19):20200-10.
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A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death. J Cell Biol. 2003 Jan 20; 160(2):223-33.
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Transforming growth factor-beta 1 signaling contributes to Caco-2 cell growth inhibition induced by 1,25(OH)(2)D(3). Am J Physiol Gastrointest Liver Physiol. 2002 Oct; 283(4):G864-74.
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Cation-independent mannose 6-phosphate receptor blocks apoptosis induced by herpes simplex virus 1 mutants lacking glycoprotein D and is likely the target of antiapoptotic activity of the glycoprotein. J Virol. 2002 Jun; 76(12):6197-204.
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The influence of ethanol exposure on insulin-like growth factor (IGF) type II receptors in fetal rat tissues. Life Sci. 1996; 59(1):51-60.