"Steroidogenic Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.
| Descriptor ID |
D054339
|
| MeSH Number(s) |
D12.776.826.925
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| Concept/Terms |
Steroidogenic Factor 1- Steroidogenic Factor 1
- Ad4-Binding Protein
- Ad4 Binding Protein
- Adrenal 4 Binding Protein
- AD4BP Protein
- Fushi Tarazu Factor Homolog 1
- NR5A1 Protein
- Nuclear Receptor 5A1 Protein
- FTZF1 Protein
- SF-1 Transcription Factor
- Transcription Factor, SF-1
- Steroid Hormone Receptor Ad4BP
|
Below are MeSH descriptors whose meaning is more general than "Steroidogenic Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Steroidogenic Factor 1".
This graph shows the total number of publications written about "Steroidogenic Factor 1" by people in this website by year, and whether "Steroidogenic Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Steroidogenic Factor 1" by people in Profiles.
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Sterol O-acyltransferase 1 (SOAT1, ACAT) is a novel target of steroidogenic factor-1 (SF-1, NR5A1, Ad4BP) in the human adrenal. J Clin Endocrinol Metab. 2011 Apr; 96(4):E663-8.
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Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus. J Neurosci. 2005 Apr 20; 25(16):4181-8.
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Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. Cell. 2005 Feb 11; 120(3):343-55.
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Modulation of human luteinizing hormone beta gene transcription by MIP-2A. J Biol Chem. 2003 Jun 27; 278(26):24033-8.