"Liver X Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating cholesterol homeostasis, ENERGY METABOLISM; INFLAMMATION; and the immune response.
| Descriptor ID |
D000071518
|
| MeSH Number(s) |
D12.776.260.531 D12.776.826.194
|
| Concept/Terms |
Liver X Receptors- Liver X Receptors
- Nuclear Oxysterol Receptors
- Oxysterol Receptors, Nuclear
- Liver X Receptor
Liver X Receptor Alpha- Liver X Receptor Alpha
- Liver X Receptor-Alpha
- NR1H3 Protein
- LXRalpha Protein
- Nuclear Orphan Receptor LXR-Alpha
- Nuclear Orphan Receptor LXR Alpha
- Oxysterols Receptor LXR-Alpha
- LXR-Alpha, Oxysterols Receptor
- Oxysterols Receptor LXR Alpha
- Nuclear Receptor Subfamily 1, Group H, Member 3
- LXR-Alpha Protein
- LXR Alpha Protein
Liver X Receptor Beta- Liver X Receptor Beta
- Liver X Receptor-Beta
- Nuclear Receptor Subfamily 1, Group H, Member 2
- Oxysterols Receptor LXR-Beta
- LXR-Beta, Oxysterols Receptor
- Oxysterols Receptor LXR Beta
- LXRbeta Protein
- NR1H2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Liver X Receptors".
Below are MeSH descriptors whose meaning is more specific than "Liver X Receptors".
This graph shows the total number of publications written about "Liver X Receptors" by people in this website by year, and whether "Liver X Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Liver X Receptors" by people in Profiles.
-
Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection. Nucleic Acids Res. 2016 12 15; 44(22):10571-10587.
-
Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis. Circulation. 2012 Oct 30; 126(18):2236-47.
-
Trans-10, cis-12 conjugated linoleic acid decreases de novo lipid synthesis in human adipocytes. J Nutr Biochem. 2012 Jun; 23(6):580-90.
-
A novel potent synthetic steroidal liver X receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR(-/-) mice. Br J Pharmacol. 2011 Apr; 162(8):1792-804.
-
Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway. J Endocrinol. 2010 May; 205(2):179-86.
-
Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling. J Biol Chem. 2010 Feb 19; 285(8):5392-404.
-
Differential effects of activation of liver X receptor on plasma lipid homeostasis in wild-type and lipoprotein clearance-deficient mice. Atherosclerosis. 2010 Jan; 208(1):126-33.
-
Pharmacological approaches to modifying HDL: more basic science to understand HDL metabolism is necessary. Editorial to: "NO-1886 up-regulates Niemann-Pick C1 protein (NPC1) expression through liver X receptor alpha signaling pathway in THP-1 macrophage-derived foam cells" by Xin Ma et al. Cardiovasc Drugs Ther. 2009 Jun; 23(3):187-8.
-
Peroxisome proliferator-activated receptor {gamma} stimulation of adipocyte ApoE gene transcription mediated by the liver receptor X pathway. J Biol Chem. 2009 Apr 17; 284(16):10453-61.
-
The G protein-coupled receptor G2A: involvement in hepatic lipid metabolism and gallstone formation in mice. Hepatology. 2008 Oct; 48(4):1138-48.