"Liver X Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear receptors that bind OXYSTEROLS and function as heterodimers with RETINOID X RECEPTORS. They have important functions in regulating cholesterol homeostasis, ENERGY METABOLISM; INFLAMMATION; and the immune response.
| Descriptor ID |
D000071518
|
| MeSH Number(s) |
D12.776.260.531 D12.776.826.194
|
| Concept/Terms |
Liver X Receptors- Liver X Receptors
- Nuclear Oxysterol Receptors
- Oxysterol Receptors, Nuclear
- Liver X Receptor
Liver X Receptor Alpha- Liver X Receptor Alpha
- Liver X Receptor-Alpha
- NR1H3 Protein
- LXRalpha Protein
- Nuclear Orphan Receptor LXR-Alpha
- Nuclear Orphan Receptor LXR Alpha
- Oxysterols Receptor LXR-Alpha
- LXR-Alpha, Oxysterols Receptor
- Oxysterols Receptor LXR Alpha
- Nuclear Receptor Subfamily 1, Group H, Member 3
- LXR-Alpha Protein
- LXR Alpha Protein
Liver X Receptor Beta- Liver X Receptor Beta
- Liver X Receptor-Beta
- Nuclear Receptor Subfamily 1, Group H, Member 2
- Oxysterols Receptor LXR-Beta
- LXR-Beta, Oxysterols Receptor
- Oxysterols Receptor LXR Beta
- LXRbeta Protein
- NR1H2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Liver X Receptors".
Below are MeSH descriptors whose meaning is more specific than "Liver X Receptors".
This graph shows the total number of publications written about "Liver X Receptors" by people in this website by year, and whether "Liver X Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Liver X Receptors" by people in Profiles.
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Adiponectin Stimulates Apolipoprotein A-1 Gene Expression in HepG2 Cells via AMPK, PPARa, and LXRs Signaling Mechanisms. Biochemistry (Mosc). 2022 Nov; 87(11):1252-1259.
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EGFR/SRC/ERK-stabilized YTHDF2 promotes cholesterol dysregulation and invasive growth of glioblastoma. Nat Commun. 2021 01 08; 12(1):177.
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Mulberry Fruit Extract Promotes Serum HDL-Cholesterol Levels and Suppresses Hepatic microRNA-33 Expression in Rats Fed High Cholesterol/Cholic Acid Diet. Nutrients. 2020 May 21; 12(5).
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Tumor necrosis factor a stimulates endogenous apolipoprotein A-I expression and secretion by human monocytes and macrophages: role of MAP-kinases, NF-?B, and nuclear receptors PPARa and LXRs. Mol Cell Biochem. 2018 Nov; 448(1-2):211-223.
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Alu repeats as transcriptional regulatory platforms in macrophage responses to M. tuberculosis infection. Nucleic Acids Res. 2016 12 15; 44(22):10571-10587.
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PPAR? Represses Apolipoprotein A-I Gene but Impedes TNFa-Mediated ApoA-I Downregulation in HepG2 Cells. J Cell Biochem. 2016 09; 117(9):2010-22.
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Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis. Circulation. 2012 Oct 30; 126(18):2236-47.
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Modified low density lipoprotein stimulates complement C3 expression and secretion via liver X receptor and Toll-like receptor 4 activation in human macrophages. J Biol Chem. 2012 Feb 17; 287(8):5954-68.
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The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors. Endocrinology. 2011 Dec; 152(12):4691-705.
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Trans-10, cis-12 conjugated linoleic acid decreases de novo lipid synthesis in human adipocytes. J Nutr Biochem. 2012 Jun; 23(6):580-90.