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Schilsky, Richard
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full name Richard Schilsky
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Concept Alleles
Concept Blood Specimen Collection
Concept Carcinoma, Squamous Cell
Concept Anti-Inflammatory Agents, Non-Steroidal
Concept Antibody Specificity
Concept Digestive System
Concept Binding Sites
Concept Carcinoma, Non-Small-Cell Lung
Concept Evaluation Studies as Topic
Concept Cell-Free System
Concept Drug Synergism
Concept Immunologic Deficiency Syndromes
Concept Decision Support Techniques
Concept DNA, Recombinant
Concept Educational Status
Concept Health Services for the Aged
Concept Gas Chromatography-Mass Spectrometry
Concept Community Health Services
Concept Cross-Sectional Studies
Concept Follicle Stimulating Hormone
Concept Feasibility Studies
Concept Financial Support
Concept Hypnotics and Sedatives
Concept Health Services Accessibility
Concept Product Surveillance, Postmarketing
Concept Neoplasm Staging
Concept Peripheral Nervous System Diseases
Concept Silicon Dioxide
Concept Nervous System
Concept Pancoast Syndrome
Concept Radiation-Sensitizing Agents
Concept Research Support as Topic
Concept Salivary Gland Neoplasms
Concept Sex
Concept Skin Ulcer
Concept Cohort Studies
Concept Genes, ras
Concept Spermatogenesis
Concept Stomatitis
Concept Sensitivity and Specificity
Concept Spain
Concept Splenectomy
Concept Societies, Medical
Concept Statistics as Topic
Concept United States
Concept United States Food and Drug Administration
Concept Uric Acid
Concept Multicenter Studies as Topic
Concept Central Nervous System Neoplasms
Concept Salvage Therapy
Concept Chi-Square Distribution
Concept Adverse Drug Reaction Reporting Systems
Concept Private Sector
Concept Drug Delivery Systems
Concept Neoplasms, Unknown Primary
Concept Sequence Analysis, DNA
Concept Prostate-Specific Antigen
Concept National Institutes of Health (U.S.)
Concept Decision Support Systems, Clinical
Concept Sepsis
Concept Von Hippel-Lindau Tumor Suppressor Protein
Concept Cross-Over Studies
Concept Public Sector
Concept In Situ Hybridization, Fluorescence
Concept Self Report
Concept Peripheral Blood Stem Cell Transplantation
Concept Carcinoma, Small Cell
Concept Sodium Azide
Concept Amino Acid Substitution
Concept Oligonucleotide Array Sequence Analysis
Concept Genes, bcl-2
Concept Health Care Sector
Concept Surveys and Questionnaires
Concept National Cancer Institute (U.S.)
Concept Sarcoma
Concept Serum Albumin
Concept Socioeconomic Factors
Concept Specimen Handling
Concept Stomach Neoplasms
Concept Sulfonamides
Concept Ubiquitin-Protein Ligases
Concept Gastrointestinal Stromal Tumors
Concept High-Throughput Nucleotide Sequencing
Concept Uracil
Concept Sex Factors
Concept Skin Neoplasms
Concept Software Design
Concept Stereoisomerism
Concept Models, Statistical
Concept Small Cell Lung Carcinoma
Concept Survival Analysis
Concept Thymidylate Synthase
Concept Survivors
Concept Genome, Human
Concept Survival Rate
Concept Granulocyte Colony-Stimulating Factor
Concept Patient Selection
Concept Karnofsky Performance Status
Concept Validation Studies as Topic
Concept Gene Silencing
Concept SEER Program
Concept Tumor Suppressor Proteins
Concept Transcriptome
Concept Genome-Wide Association Study
Concept Secondary Prevention
Concept Standard of Care
Concept Drug Administration Schedule
Concept Drug Screening Assays, Antitumor
Concept Follow-Up Studies
Concept Health Services Research
Concept Injections, Subcutaneous
Concept Prospective Studies
Concept Retrospective Studies
Concept Serum Albumin, Bovine
Concept Spermatozoa
Concept Urogenital Neoplasms
Concept Signal Transduction
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Disease-Free Survival
Concept Unnecessary Procedures
Concept Polymorphism, Single Nucleotide
Concept Research Subjects
Concept Patient Safety
Academic Article 5-Fluorouracil, hydroxyurea and escalating doses of iododeoxyuridine with concomitant radiotherapy for malignant gliomas: a clinical and pharmacologic analysis.
Academic Article Phase I study of amonafide dosing based on acetylator phenotype.
Academic Article Statistical and ethical issues in the design and conduct of phase I and II clinical trials of new anticancer agents.
Academic Article Phase I clinical and pharmacology study of 502U83 given as a 24-h continuous intravenous infusion.
Academic Article Update on biochemical modulation of chemotherapeutic agents.
Academic Article Adjuvant therapy of colon cancer.
Academic Article Methotrexate: an effective agent for treating cancer and building careers. The polyglutamate era.
Academic Article Adjuvant therapy for colorectal cancer.
Academic Article Treatment-related fatal sepsis from topotecan/cisplatin and topotecan/paclitaxel.
Academic Article Biochemical pharmacology of chemotherapeutic drugs used as radiation enhancers.
Academic Article Individualized dosing of amonafide based on a pharmacodynamic model incorporating acetylator phenotype and gender.
Academic Article Prospects for fertility after cancer chemotherapy.
Academic Article Relationship between toxicity and obesity in women receiving adjuvant chemotherapy for breast cancer: results from cancer and leukemia group B study 8541.
Academic Article Phase I study of 3'-deamino-3'-(2-methoxy-4-morpholinyl)doxorubicin (FCE 23762, PNU 152243) administered on a daily x3 schedule.
Academic Article Safety and efficacy of using a single agent or a phase II agent before instituting standard combination chemotherapy in previously untreated metastatic breast cancer patients: report of a randomized study--Cancer and Leukemia Group B 8642.
Academic Article Phase I clinical and pharmacokinetic study of oral 9-aminocamptothecin (NSC-603071).
Academic Article Phase I study of treatment with oral 13-cis-retinoic acid, subcutaneous interferon alfa-2a, cisplatin, and 24-hour infusion 5-fluorouracil/leucovorin.
Academic Article Biochemical and clinical pharmacology of 5-fluorouracil.
Academic Article An investigational new drug treatment program for patients with gemcitabine: results for over 3000 patients with pancreatic carcinoma.
Academic Article Antifolates: the next generation.
Academic Article Eniluracil: an irreversible inhibitor of dihydropyrimidine dehydrogenase.
Academic Article Phase II trial of 150-minute weekly infusion of gemcitabine in advanced colorectal cancer: minimal activity in colorectal cancer.
Academic Article Phase I and pharmacokinetic trial of paclitaxel in patients with hepatic dysfunction: Cancer and Leukemia Group B 9264.
Academic Article Phase I study of ZD9331 on short daily intravenous bolus infusion for 5 days every 3 weeks with fixed dosing recommendations.
Academic Article Phase I and pharmacologic study of continuous infusion topotecan in combination with cisplatin in patients with advanced cancer: a Cancer and LeukemiaGroup B study.
Academic Article Phase II trial of uracil/tegafur (UFT) plus leucovorin in patients with advanced biliary carcinoma.
Academic Article Multicenter phase II study to evaluate a 28-day regimen of oral fluorouracil plus eniluracil in the treatment of patients with previously untreated metastatic colorectal cancer.
Academic Article Pharmacology of 21-day oral etoposide given in combination with i.v. cisplatin in patients with extensive-stage small cell lung cancer: a cancer and leukemia group B study (CALGB 9062).
Academic Article Phase II study of oral eniluracil, 5-fluorouracil, and leucovorin in patients with advanced colorectal carcinoma.
Academic Article Construct validity of medicare chemotherapy claims: the case of 5FU.
Academic Article End points in cancer clinical trials and the drug approval process.
Academic Article Estimation of the effect of food on the disposition of oral 5-fluorouracil in combination with eniluracil.
Academic Article A double-blind placebo-controlled randomized phase III trial of 5-fluorouracil and leucovorin, plus or minus trimetrexate, in previously untreated patients with advanced colorectal cancer.
Academic Article UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity.
Academic Article Cooperative group tissue banks as research resources: the cancer and leukemia group B tissue repositories.
Academic Article High dose cyclophosphamide plus recombinant human granulocyte-colony stimulating factor (rhG-CSF) in the treatment of follicular, low grade non-Hodgkin's lymphoma: CALGB 9150.
Academic Article Hydroxyurea with concomitant radiotherapy for locally advanced head and neck cancer.
Academic Article Laboratory and clinical studies of biochemical modulation by hydroxyurea.
Academic Article Pharmacology and clinical status of capecitabine.
Academic Article Antineoplastic drugs administered during pregnancy.
Academic Article Phase I clinical and pharmacogenetic study of weekly TAS-103 in patients with advanced cancer.
Academic Article A multicenter phase II study of a five-day regimen of oral 5-fluorouracil plus eniluracil with or without leucovorin in patients with metastatic colorectal cancer.
Academic Article Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer.
Academic Article Induction chemotherapy with cisplatin, fluorouracil, and high-dose leucovorin for locally advanced head and neck cancer: a clinical and pharmacologic analysis.
Academic Article Five-day infusion of fluorodeoxyuridine with high-dose oral leucovorin: a phase I study.
Academic Article Silence is golden: gene hypermethylation and survival in large-cell lymphoma.
Academic Article Dose-escalating study of capecitabine plus gemcitabine combination therapy in patients with advanced cancer.
Academic Article Phase I study to evaluate multiple regimens of intravenous 5-fluorouracil administered in combination with weekly gemcitabine in patients with advanced solid tumors: a potential broadly active regimen for advanced solid tumor malignancies.
Academic Article A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer.
Academic Article Tumor markers as clinical cancer tests--are we there yet?
Academic Article First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous 5-fluorouracil/leucovorin.
Academic Article Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741.
Academic Article Oncology physician and nurse practices and attitudes regarding offering clinical trial results to study participants.
Academic Article Paradoxical relationship between acetylator phenotype and amonafide toxicity.
Academic Article Colorectal adenomas: a prototype for the use of surrogate end points in the development of cancer prevention drugs.
Academic Article Hurry up and wait: is accelerated approval of new cancer drugs in the best interests of cancer patients?
Academic Article Cytosine arabinoside and cisplatin for advanced breast cancer. A phase II study of the Cancer and Leukemia Group B.
Academic Article Inhibiting 5-fluorouracil breakdown: a broken down approach to 5-fluorouracil modulation.
Academic Article A phase I study of cantuzumab mertansine administered as a single intravenous infusion once weekly in patients with advanced solid tumors.
Academic Article A phase I trial of escalating doses of trastuzumab combined with daily subcutaneous interleukin 2: report of cancer and leukemia group B 9661.
Academic Article A phase I study of the oral combination of CI-994, a putative histone deacetylase inhibitor, and capecitabine.
Academic Article Prospective, randomized comparison of high-dose chemotherapy with stem-cell support versus intermediate-dose chemotherapy after surgery and adjuvant chemotherapy in women with high-risk primary breast cancer: a report of CALGB 9082, SWOG 9114, and NCIC MA-13.
Academic Article Highlights from: 27th congress of the European Society for Medical Oncology. Nice, France. October 18-22, 2002.
Academic Article A concise history of the cancer and leukemia group B.
Academic Article Criterion validity of Medicare chemotherapy claims in Cancer and Leukemia Group B breast and lung cancer trial participants.
Academic Article Cancer and Leukemia Group B 90206: A randomized phase III trial of interferon-alpha or interferon-alpha plus anti-vascular endothelial growth factor antibody (bevacizumab) in metastatic renal cell carcinoma.
Academic Article Platinum-based combination chemotherapy in advanced non-small cell lung cancer: a randomized phase II trial of the Cancer and Leukemia Group B.
Academic Article Chronic calcium antagonist use in carcinoma of the lung and colon: a retrospective cohort observational study.
Academic Article The role of cooperative groups in cancer clinical trials.
Academic Article Drug safety and drug efficacy: two sides of the same coin.
Academic Article Phase I clinical and pharmacologic study of intraperitoneal cisplatin and fluorouracil in patients with advanced intraabdominal cancer.
Academic Article American Society of Clinical Oncology Statement on minimum standards and exemplary attributes of clinical trial sites.
Academic Article Clinical pharmacokinetics of high-dose leucovorin calcium after intravenous and oral administration.
Academic Article The Translational Research Working Group developmental pathway for anticancer agents (drugs or biologics).
Academic Article Introduction: contributions of the cooperative groups.
Academic Article Biomarkers, surrogate end points, and the acceleration of drug development for cancer prevention and treatment: an update prologue.
Academic Article Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.
Academic Article A phase I study of antisense oligonucleotide GTI-2040 given by continuous intravenous infusion in patients with advanced solid tumors.
Academic Article First-line treatment options for patients with metastatic colorectal cancer.
Academic Article Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803.
Academic Article Are targeted therapies really targeted?
Academic Article Personalizing cancer care: American Society of Clinical Oncology presidential address 2009.
Academic Article Pharmacologically based dosing of etoposide: a means of safely increasing dose intensity.
Academic Article Inhibition of thymidylate synthase by the diastereoisomers of leucovorin.
Academic Article The cancer and leukemia group B pharmacology and experimental therapeutics committee: a historical perspective.
Academic Article Translating the cancer genome into clinically useful tools and strategies.
Academic Article Refocusing the war on cancer: the critical role of personalized treatment.
Academic Article Personalized medicine in oncology: the future is now.
Academic Article A Cancer and Leukemia Group B phase II study of sunitinib malate in patients with previously treated metastatic pancreatic adenocarcinoma (CALGB 80603).
Academic Article Clinical cancer advances 2006: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.
Academic Article Optimizing collection of adverse event data in cancer clinical trials supporting supplemental indications.
Academic Article Nonmalignant complications of therapy for Hodgkin's disease.
Academic Article Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation.
Academic Article Male fertility following cancer chemotherapy.
Academic Article Hypomagnesemia and renal magnesium wasting in patients receiving cisplatin.
Academic Article Cancer and Leukemia Group B Pathology Committee guidelines for tissue microarray construction representing multicenter prospective clinical trial tissues.
Academic Article Concomitant 5-FU, hydroxyurea and cisplatin with external beam radiation therapy for locally advanced pancreatic cancer.
Academic Article Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups.
Academic Article Tomorrow's cancer treatments today: the first 50 years of the Cancer and Leukemia Group B.
Academic Article Zoledronic acid preserves bone mineral density in premenopausal women who develop ovarian failure due to adjuvant chemotherapy: final results from CALGB trial 79809.
Academic Article Vascular events in patients receiving high-dose infusional 5-fluorouracil-based chemotherapy: the University of Chicago experience.
Academic Article Tumor heterogeneity as the foundation of personalized cancer treatment.
Academic Article A randomized study of inpatient versus outpatient continuous intravenous infusion chemotherapy: psychosocial aspects.
Academic Article WIN Consortium--challenges and advances.
Academic Article Clinical cancer advances 2007: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology.
Academic Article Resolution of the stereoisomers of leucovorin and 5-methyltetrahydrofolate by chiral high-performance liquid chromatography.
Academic Article Ethical, scientific, and regulatory perspectives regarding the use of placebos in cancer clinical trials.
Academic Article Biological, clinical, and psychosocial correlates at the interface of cancer and aging research.
Academic Article Personalized cancer medicine - a strategy to counteract an increasing cancer challenge.
Academic Article Adaptive control of etoposide administration: impact of interpatient pharmacodynamic variability.
Academic Article Clinical pharmacology of the stereoisomers of leucovorin during repeated oral dosing.
Academic Article Development and use of integral assays in clinical trials.
Academic Article Concomitant hydroxyurea, 5-fluorouracil, and radiation therapy for recurrent head and neck cancer: early results.
Academic Article Measuring clinically significant chemotherapy-related toxicities using Medicare claims from Cancer and Leukemia Group B (CALGB) trial participants.
Academic Article How not to treat cancer.
Academic Article Accrual to cancer clinical trials in the era of molecular medicine.
Academic Article Infertility in patients with testicular cancer: testis, tumor, or treatment?
Academic Article Chemotherapy for testicular cancer: current status of the National Cancer Institute Combined Modality Trial.
Academic Article Cisplatin, fluorouracil, and high-dose leucovorin for recurrent or metastatic head and neck cancer.
Academic Article Phase I clinical and pharmacological study of 72-hour continuous infusion of etoposide in patients with advanced cancer.
Academic Article The synthesis and retention of methotrexate polyglutamates in cultured human breast cancer cells.
Academic Article Gallium-67 scanning: limited usefulness in staging patients with non-Hodgkin's lymphoma.
Academic Article Prognostic factors for survival in patients treated in phase I clinical trials.
Academic Article Phase I trial of granulocyte-macrophage colony-stimulating factor plus high-dose cyclophosphamide given every 2 weeks: a Cancer and Leukemia Group B study.
Academic Article Sequential hydroxyurea-cytarabine chemotherapy for refractory non-Hodgkin's lymphoma.
Academic Article Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells.
Academic Article Molecular markers to individualize adjuvant therapy for colon cancer.
Academic Article A randomized study of inpatient versus outpatient continuous infusion chemotherapy for patients with locally advanced head and neck cancer.
Academic Article Data submission standards and evidence requirements.
Academic Article Effects of cancer treatment on the reproductive system.
Academic Article Diagnosis, management, and evaluation of chemotherapy-induced peripheral neuropathy.
Academic Article GI cancers in 2010: New standards and a predictive biomarker for adjuvant therapy.
Academic Article Toxic effects of cis-dichlorodiammineplatinum(II) in man.
Academic Article A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
Academic Article Phase I clinical evaluation of cytarabine and cisplatin in patients with advanced cancer.
Academic Article Tumor cell heterogeneity: implications for clinical practice.
Academic Article Phase I study of topotecan and cisplatin in patients with advanced solid tumors: a cancer and leukemia group B study.
Academic Article Update in hematology and oncology: evidence published in 2010.
Academic Article Hydroxyurea, fluorouracil, and concomitant radiotherapy in poor-prognosis head and neck cancer: a phase I-II study.
Academic Article Cytarabine-cis-platin interactions in patients with advanced cancer.
Academic Article Simultaneous determination of cytosine arabinoside, its nucleotides and metabolites by ion-pair high-performance liquid chromatography.
Academic Article Evaluation of cognition in cancer patients: special focus on the elderly.
Academic Article Measuring disease-free survival and cancer relapse using Medicare claims from CALGB breast cancer trial participants (companion to 9344).
Academic Article Synthesis, binding and intracellular retention of methotrexate polyglutamates by cultured human breast cancer cells.
Academic Article Using patient-initiated study participation in the development of evidence for personalized cancer therapy.
Academic Article Gonadal dysfunction in patients receiving chemotherapy for cancer.
Academic Article Renal and metabolic toxicities of cancer chemotherapy.
Academic Article Clinical cardiotoxicity of esorubicin (4'-deoxydoxorubicin,DxDx): prospective studies with serial gated heart scans and reports of selected cases. A Cancer and Leukemia Group B report.
Academic Article Patient advocates' role in clinical trials: perspectives from Cancer and Leukemia Group B investigators and advocates.
Academic Article Phase II study of fludarabine phosphate for gastric adenocarcinoma. An Illinois Cancer Center trial.
Academic Article Scarcity of vital oncology drugs: finding long-term solutions.
Academic Article Targeted therapy for cancer: asking the right questions.
Academic Article Population pharmacodynamic study of amonafide: a Cancer and Leukemia Group B study.
Academic Article Sequential therapy with dacarbazine and carmustine: a phase I study.
Academic Article Human pharmacokinetics, excretion, and metabolism of the anthracycline antibiotic menogaril (7-OMEN, NSC 269148) and their correlation with clinical toxicities.
Academic Article Gonadal and sexual function in male patients with hairy cell leukemia: lack of adverse effects of recombinant alpha 2-interferon treatment.
Academic Article Hydroxyurea and etoposide: in vitro synergy and phase I clinical trial.
Academic Article A phase I study of intermittent infusion cladribine in patients with solid tumors.
Academic Article Phase I and pharmacokinetic study of a new antineoplastic agent: pyrazine diazohydroxide (NSC 361456).
Academic Article Phase I clinical and pharmacological study of thymidine (NSC 21548) and cis-diamminedichloroplatinum(II) in patients with advanced cancer.
Academic Article Clinical pharmacology of methotrexate.
Academic Article Persistent hypomagnesemia following cisplatin chemotherapy for testicular cancer.
Academic Article Phase I study of paclitaxel and topotecan in patients with advanced tumors: a cancer and leukemia group B study.
Academic Article Five-day infusional fluorodeoxyuridine with oral leucovorin and escalating doses of interferon alpha-2b: a phase I study.
Academic Article American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy.
Academic Article Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward.
Academic Article Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).
Academic Article Ovarian function following radiation and chemotherapy for cancer.
Academic Article The next phase of chemoprevention research.
Academic Article Limited sampling models for amonafide (NSC 308847) pharmacokinetics.
Academic Article Synthesis, retention, and biological activity of methotrexate polyglutamates in cultured human breast cancer cells.
Academic Article Phase III randomized study to compare interferon alfa-2a in combination with fluorouracil versus fluorouracil alone in patients with advanced colorectal cancer.
Academic Article Long-term follow up of ovarian function in women treated with MOPP chemotherapy for Hodgkin's disease.
Academic Article MOPP/ABV hybrid chemotherapy for advanced Hodgkin's disease significantly improves failure-free and overall survival: the 8-year results of the intergroup trial.
Academic Article Phase I clinical and pharmacological study of iododeoxyuridine and bleomycin in patients with advanced cancer.
Academic Article Phase II study of amonafide in gastric adenocarcinoma. An Illinois Cancer Center trial.
Academic Article Phase I clinical and pharmacologic study of eniluracil plus fluorouracil in patients with advanced cancer.
Academic Article Phase II and pharmacodynamic studies of pyrazine diazohydroxide (NSC 361456) in patients with advanced renal and colorectal cancer.
Academic Article Modulation of vinblastine resistance in metastatic renal cell carcinoma with cyclosporine A or tamoxifen: a cancer and leukemia group B study.
Academic Article Phase II trial of uracil/tegafur (UFT) plus leucovorin in patients with advanced pancreatic carcinoma: a University of Chicago phase II consortium study.
Academic Article The oral fluoropyrimidines in cancer chemotherapy.
Academic Article Phase I clinical and pharmacological study of O6-benzylguanine followed by carmustine in patients with advanced cancer.
Academic Article Recommendation for caution with irinotecan, fluorouracil, and leucovorin for colorectal cancer.
Academic Article Randomized, open-label, phase III study of a 28-day oral regimen of eniluracil plus fluorouracil versus intravenous fluorouracil plus leucovorin as first-line therapy in patients with metastatic/advanced colorectal cancer.
Academic Article Phase II study of echinomycin in patients with advanced breast cancer: a report of Cancer and Leukemia Group B protocol 8641.
Academic Article A phase I study of cisplatin, 5-fluorouracil and leucovorin with escalating doses of hydroxyurea in chemotherapy naive patients.
Academic Article Phase I study of an oral formulation of ZD9331 administered daily for 28 days.
Academic Article Phase I and pharmacokinetic study of 24-hour infusion 5-fluorouracil and leucovorin in patients with organ dysfunction.
Academic Article Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomised, phase III trials.
Academic Article A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital.
Academic Article Modulation of vinblastine resistance with cyclosporine: a phase I study.
Academic Article Phase I study of adozelesin administered by 24-hour continuous intravenous infusion.
Academic Article Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development.
Academic Article Processes to activate phase III clinical trials in a Cooperative Oncology Group: the Case of Cancer and Leukemia Group B.
Academic Article A phase II prospective multi-institutional trial of adjuvant active specific immunotherapy following curative resection of colorectal cancer hepatic metastases: cancer and leukemia group B study 89903.
Academic Article Insulin effects on methotrexate polyglutamate synthesis and enzyme binding in cultured human breast cancer cells.
Academic Article The impact of the privacy rule on cancer research: variations in attitudes and application of regulatory standards.
Academic Article An accelerated pathway for targeted cancer therapies.
Academic Article Phase-I trial of Thiotepa, granulocyte-macrophage colony-stimulating factor and prednisone or pentoxifylline in patients with refractory solid tumors.
Academic Article Cisplatin, 5-fluorouracil, and high-dose oral leucovorin for advanced head and neck cancer.
Academic Article Role of randomized phase III trials in an era of effective targeted therapies.
Academic Article Sequential administration of methotrexate, cisplatin, and 5-fluorouracil in multimodal therapy for locally advanced head and neck cancer.
Academic Article Methotrexate polyglutamate synthesis by cultured human breast cancer cells.
Academic Article Characteristics of membrane transport of methotrexate by cultured human breast cancer cells.
Academic Article Evaluation of food effect on pharmacokinetics of vismodegib in advanced solid tumor patients.
Academic Article Prevalence of off-label use and spending in 2010 among patent-protected chemotherapies in a population-based cohort of medical oncologists.
Academic Article Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer.
Academic Article Designing therapeutic clinical trials for older and frail adults with cancer: U13 conference recommendations.
Academic Article Clinical cancer advances 2015: Annual report on progress against cancer from the American Society of Clinical Oncology.
Academic Article Generalizability of trial results to elderly Medicare patients with advanced solid tumors (Alliance 70802).
Academic Article Circadian variation in plasma 5-fluorouracil concentrations during a 24 hour constant-rate infusion.
Academic Article First-in-human, phase I study of elisidepsin (PM02734) administered as a 30-min or as a 3-hour intravenous infusion every three weeks in patients with advanced solid tumors.
Academic Article American Society of Clinical Oncology Statement: A Conceptual Framework to Assess the Value of Cancer Treatment Options.
Academic Article Clinical Cancer Advances 2016: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology.
Academic Article Updating the American Society of Clinical Oncology Value Framework: Revisions and Reflections in Response to Comments Received.
Academic Article Enrollment Trends and Disparity Among Patients With Lung Cancer in National Clinical Trials, 1990 to 2012.
Academic Article Effect of First-Line Chemotherapy Combined With Cetuximab or Bevacizumab on Overall Survival in Patients With KRAS Wild-Type Advanced or Metastatic Colorectal Cancer: A Randomized Clinical Trial.
Academic Article Precision cancer medicine: the future is now, only better.
Academic Article Building a rapid learning health care system for oncology: the regulatory framework of CancerLinQ.
Academic Article Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015.
Academic Article Biologic determinants of tumor recurrence in stage II colon cancer: validation study of the 12-gene recurrence score in cancer and leukemia group B (CALGB) 9581.
Academic Article Breaking a vicious cycle.
Academic Article Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement.
Academic Article Progress against GI cancer during the American Society of Clinical Oncology's first 50 years.
Academic Article Highlights from the 2016 WIN Symposium, 27-29 June 2016, Paris: personalised therapy beyond next-generation sequencing.
Academic Article Association of Biomarker-Based Treatment Strategies With Response Rates and Progression-Free Survival in Refractory Malignant Neoplasms: A Meta-analysis.
Academic Article American Society of Clinical Oncology perspective: Raising the bar for clinical trials by defining clinically meaningful outcomes.
Academic Article Drivers of change in cancer care.
Academic Article Advanced clinical trials for China.
Academic Article Global Challenges for Cancer Imaging.
Academic Article Access versus evidence: The regulators' dilemma.
Academic Article A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer.
Academic Article Transformation of Health Care - Perspectives of Opinion Leaders.
Academic Article Highlights from the 2013 WIN Symposium: personalised cancer therapy from innovation to implementation.
Academic Article Strategies to overcome clinical, regulatory, and financial challenges in the implementation of personalized medicine.
Academic Article ASCO's initiative to define value in cancer care.
Academic Article Hans Christian Andersen and the Value of New Cancer Treatments.
Academic Article Trial Reporting in Immuno-Oncology (TRIO): An American Society of Clinical Oncology-Society for Immunotherapy of Cancer Statement.
Academic Article Trial Reporting in Immuno-Oncology (TRIO): an American society of clinical oncology-society for immunotherapy of cancer statement.
Academic Article Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group.
Academic Article Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review.
Academic Article Core Clinical Data Elements for Cancer Genomic Repositories: A Multi-stakeholder Consensus.
Academic Article Reply to S.D. Lucio.
Academic Article Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance).
Academic Article Risk of Neutropenia-Related Hospitalization in Patients Who Received Colony-Stimulating Factors With Chemotherapy for Breast Cancer.
Academic Article Reevaluating the accelerated approval process for oncology drugs.
Academic Article A New Look at the State of Cancer Care in America.
Academic Article Publicly funded clinical trials and the future of cancer care.
Academic Article Opportunities for translational epidemiology: the important role of observational studies to advance precision oncology.
Academic Article Challenges in initiating and conducting personalized cancer therapy trials: perspectives from WINTHER, a Worldwide Innovative Network (WIN) Consortium trial.
Academic Article Converging on the Value of Value Frameworks.
Academic Article Clinical Cancer Advances 2017: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology.
Academic Article Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review.
Academic Article Rationale, Opportunities, and Reality of Biosimilar Medications.
Academic Article Integrating biomarkers in colorectal cancer trials in the West and China.
Academic Article Reply to J.P. Jansen, A. Messori et al, and H.S.L. Jim et al.
Academic Article A New IDEA in Adjuvant Chemotherapy for Colon Cancer.
Academic Article Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-analysis of Clinical Trials Leading to FDA Approval.
Academic Article Finding the Evidence in Real-World Evidence: Moving from Data to Information to Knowledge.
Academic Article American Society of Clinical Oncology 2013 top five list in oncology.
Academic Article Wither the cooperative groups?
Academic Article Clinical Cancer Advances 2018: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology.
Academic Article Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015 Summary.
Academic Article Using Big Data to Track Trends in Medical Practice.
Academic Article Highlights from the 2015 WIN Symposium: novel targets, innovative agents, and advanced technologies-a WINning strategy?
Academic Article Reply to L.k. Griffeth et al and J.E. Battley et al.
Academic Article Improving evidence developed from population-level experience with targeted agents.
Academic Article Leveraging biospecimen resources for discovery or validation of markers for early cancer detection.
Academic Article In Memoriam: James Frederick Holland, 1925 to 2018.
Academic Article Reply to F.E. Vera-Badillo et al.
Academic Article Streamlining Adverse Events Reporting in Oncology: An American Society of Clinical Oncology Research Statement.
Academic Article The State of Oncology Practice in America, 2018: Results of the ASCO Practice Census Survey.
Academic Article Gains Against Cancer, But Enter 'Financial Toxicity'.
Academic Article American Society of Clinical Oncology Statement: Biosimilars in Oncology.
Academic Article Modernizing Eligibility Criteria for Molecularly Driven Trials.
Grant Cancer Center Support Grant
Academic Article Rationale and Design of the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Clinical Cancer Advances 2019: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology.
Academic Article Comparative Assessment of Clinical Benefit Using the ESMO-Magnitude of Clinical Benefit Scale Version 1.1 and the ASCO Value Framework Net Health Benefit Score.
Academic Article State of Cancer Care in America: Reflections on an Inaugural Year.
Academic Article Implementing Precision Medicine in Community-Based Oncology Programs: Three Models.
Academic Article Letter to the Editor: When Expertly Applied, ESMO-MCBS and ASCO Net Health Benefit Scores Usually Agree.
Academic Article Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial.
Academic Article Improving Cancer Diagnosis and Care: Patient Access to Oncologic Imaging Expertise.
Academic Article Determining If a Somatic Tumor Mutation Is Targetable and Options for Accessing Targeted Therapies.
Academic Article The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.
Academic Article Effect of Public Deliberation on Patient Attitudes Regarding Consent and Data Use in a Learning Health Care System for Oncology.
Academic Article Challenges and Opportunities to Updating Prescribing Information for Longstanding Oncology Drugs.
Academic Article Discrepancies in Financial Self-Disclosures and Open Payments Reporting Among Authors of Clinical Oncology Research Studies.
Academic Article Clinical Cancer Advances 2020: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology.
Academic Article Challenges and Opportunities to Updating Prescribing Information for Longstanding Oncology Drugs.
Academic Article Status Update on Data Required to Build a Learning Health System.
Academic Article Patient Preferences Regarding Informed Consent Models for Participation in a Learning Health Care System for Oncology.
Academic Article Early Impact of COVID-19 on the Conduct of Oncology Clinical Trials and Long-Term Opportunities for Transformation: Findings From an American Society of Clinical Oncology Survey.
Academic Article Closing the Rural Cancer Care Gap: Three Institutional Approaches.
Academic Article Progress in Cancer Research, Prevention, and Care.
Academic Article The National Clinical Trials Network and the cooperative groups: The road not taken.
Academic Article Delivering Cancer Care During the COVID-19 Pandemic: Recommendations and Lessons Learned From ASCO Global Webinars.
Academic Article Development and Validation of a Natural Language Processing Tool to Generate the CONSORT Reporting Checklist for Randomized Clinical Trials.
Academic Article Sunitinib in Patients with Metastatic Colorectal Cancer (mCRC) with FLT-3 Amplification: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Cetuximab in Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Ovarian Cancer Without KRAS, NRAS, or BRAF Mutations: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Governance of a Learning Health Care System for Oncology: Patient Recommendations.
Academic Article American Society of Clinical Oncology Road to Recovery Report: Learning From the COVID-19 Experience to Improve Clinical Research and Cancer Care.
Academic Article Recommendations to Streamline and Standardize Clinical Trial Site Feasibility Assessments: An ASCO Research Statement.
Academic Article Clinical Cancer Advances 2021: ASCO's Report on Progress Against Cancer.
Academic Article Continuing to Broaden Eligibility Criteria to Make Clinical Trials More Representative and Inclusive: ASCO-Friends of Cancer Research Joint Research Statement.
Academic Article Impact of Broadening Trial Eligibility Criteria for Patients with Advanced Non-Small Cell Lung Cancer: Real-World Analysis of Select ASCO-Friends Recommendations.
Academic Article Pembrolizumab in Patients With Metastatic Breast Cancer With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Digital Display Precision Predictor: the prototype of a global biomarker model to guide treatments with targeted therapy and predict progression-free survival.
Academic Article 'Strategic' development of precision cancer medicine in the United States.
Academic Article The Porto European Cancer Research Summit 2021.
Academic Article Changes Over Time in COVID-19 Severity and Mortality in Patients Undergoing Cancer Treatment in the United States: Initial Report From the ASCO Registry.
Academic Article Patient Experiences, Trust, and Preferences for Health Data Sharing.
Academic Article Palbociclib in Patients With Non-Small-Cell Lung Cancer With CDKN2A Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Use of Biosimilar Medications in Oncology.
Academic Article Palbociclib in Patients With Pancreatic and Biliary Cancer With CDKN2A Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Use of Next-Generation Sequencing Tests to Guide Cancer Treatment: Results From a Nationally Representative Survey of Oncologists in the United States.
Academic Article A WIN Consortium phase I study exploring avelumab, palbociclib, and axitinib in advanced non-small cell lung cancer.
Academic Article Beyond the COVID-19 Pandemic: Sustaining and Improving Equitable Cancer Care and Research.
Academic Article Pertuzumab Plus Trastuzumab in Patients With Colorectal Cancer With ERBB2 Amplification or ERBB2/3 Mutations: Results From the TAPUR Study.
Academic Article Transcriptomics in Tumor and Normal Lung Tissues Identify Patients With Early-Stage Non-Small-Cell Lung Cancer With High Risk of Postsurgery Recurrence Who May Benefit From Adjuvant Therapies.
Academic Article Cobimetinib Plus Vemurafenib in Patients With Colorectal Cancer With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Olaparib in Patients With Metastatic Prostate Cancer With BRCA1/2 Mutation: Results From the TAPUR Study.
Concept Stakeholder Participation
Concept Drug-Related Side Effects and Adverse Reactions
Concept Observational Studies as Topic
Grant Cancer and Leukemia Group B
Grant Cancer and Leukemia Group B Human Specimen Repositories
Grant CANCER AND LEUKEMIA GROUP B--PET COMMITTEE
Grant CALGB STUDIES OF BREAST CANCER IN THE ELDERLY
Grant Cancer and Leukemia Group B CCOP Research Base
Grant CELLULAR PHARMACOLOGY OF THE STEREOISOMERS OF LEUCOVORIN
Academic Article Pertuzumab Plus Trastuzumab in Patients With Endometrial Cancer With ERBB2/3 Amplification, Overexpression, or Mutation: Results From the TAPUR Study.
Academic Article Pertuzumab Plus Trastuzumab in Patients With Lung Cancer With ERBB2 Mutation or Amplification: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Health Data Sharing Perspectives of Patients Receiving Care in CancerLinQ-Participating Oncology Practices.
Academic Article The Targeted Agent and Profiling Utilization Registry Study: A pragmatic clinical trial.
Academic Article Pembrolizumab in Patients With Tumors With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Nivolumab Plus Ipilimumab in Patients With Solid Tumors With ATM Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
Academic Article Cobimetinib Plus Vemurafenib in Patients With Solid Tumors With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Sunitinib in Patients With Breast Cancer With FGFR1 or FGFR2 Amplifications or Mutations: Results From the Targeted Agent and Profiling Utilization Registry Study.
Academic Article Concordance in Molecular Tumor Board Case Reviews in the ASCO TAPUR Study.
Academic Article Regorafenib in Patients With Solid Tumors With BRAF Alterations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
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