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O'Donnell, Peter H.
One or more keywords matched the following items that are connected to O'Donnell, Peter H.
Item TypeName
Concept Action Potentials
Concept Age Factors
Concept Academic Medical Centers
Concept Antibodies, Neoplasm
Concept Antibodies, Viral
Concept Analgesics, Opioid
Concept Blood Platelets
Concept Alleles
Concept Adenosine Triphosphate
Concept Administration, Oral
Concept Antineoplastic Agents
Concept Cell Line, Transformed
Concept Ceramides
Concept Antimetabolites, Antineoplastic
Concept Carcinoma
Concept Anesthetics
Concept Antibodies, Monoclonal
Concept Codeine
Concept Benzamides
Concept BCG Vaccine
Concept DNA Damage
Concept Carcinoma, Renal Cell
Concept Carcinoma, Transitional Cell
Concept BK Virus
Concept Biopsy
Concept Epilepsies, Myoclonic
Concept Fanconi Anemia
Concept Cholesterol, Dietary
Concept Chicago
Concept Cisplatin
Concept Creatinine
Concept Contrast Media
Concept Diabetes Mellitus, Type 2
Concept Diarrhea
Concept Insulin
Concept Endothelium, Vascular
Concept Decision Support Techniques
Concept DNA Repair
Concept Chemotaxis, Leukocyte
Concept Disease Susceptibility
Concept Endonucleases
Concept G(M2) Ganglioside
Concept Liver Neoplasms
Concept Herpesvirus 4, Human
Concept Infusions, Intravenous
Concept Genetics, Medical
Concept Genetics, Population
Concept Pharmacogenetics
Concept Immunohistochemistry
Concept Orchiectomy
Concept Microsomes, Liver
Concept Patient Education as Topic
Concept Laparoscopy
Concept Oxycodone
Concept Prostatic Neoplasms
Concept Recurrence
Concept Receptors, Cell Surface
Concept Risk Factors
Concept Receptors, LDL
Concept Cohort Studies
Concept RNA Polymerase II
Concept Tay-Sachs Disease
Concept Incidence
Concept Cluster Analysis
Concept Transcription, Genetic
Concept Software
Concept Succinylcholine
Concept Clinical Trials, Phase I as Topic
Concept Warfarin
Concept Vaccination
Concept Hematopoietic Stem Cell Transplantation
Concept Randomized Controlled Trials as Topic
Concept Tumor Cells, Cultured
Concept Cell Adhesion Molecules
Concept Metabolic Clearance Rate
Concept Leukemia, Myeloid, Acute
Concept Parathyroidectomy
Concept Lymphocytes, Tumor-Infiltrating
Concept Gene Expression
Concept Stem Cell Transplantation
Concept Clinical Trials, Phase II as Topic
Concept Case-Control Studies
Concept CD8-Positive T-Lymphocytes
Concept Cell Proliferation
Concept Genes, X-Linked
Concept Disease Progression
Concept Antineoplastic Agents, Alkylating
Concept Transgenes
Concept Angiogenesis Inhibitors
Concept Cytochrome P-450 CYP2D6
Concept Receptor, ErbB-3
Concept Collagen Type I
Concept Fatal Outcome
Concept Vascular Endothelial Growth Factor Receptor-2
Concept B7-H1 Antigen
Concept Primary Cell Culture
Concept Population Groups
Concept Methylenetetrahydrofolate Reductase (NADPH2)
Concept Area Under Curve
Concept 5' Untranslated Regions
Concept Response Elements
Concept Evidence-Based Medicine
Concept Platinum
Concept Promoter Regions, Genetic
Concept Stomach Neoplasms
Concept Quality Improvement
Concept Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Concept Benzodioxoles
Concept Antibodies, Monoclonal, Humanized
Concept Transcription Factor RelA
Concept Tunica Intima
Concept Survival Rate
Concept Transplantation Chimera
Concept Receptor, ErbB-2
Concept Vascular Cell Adhesion Molecule-1
Concept Urothelium
Concept Carotid Artery Injuries
Concept Basic Helix-Loop-Helix Transcription Factors
Concept Genome-Wide Association Study
Concept Precision Medicine
Concept Programmed Cell Death 1 Receptor
Concept Cell Line, Tumor
Concept CREB-Binding Protein
Concept Receptor, Fibroblast Growth Factor, Type 3
Concept Brain Neoplasms
Concept Cell Line
Concept Cells, Cultured
Concept Clinical Trials as Topic
Concept Data Interpretation, Statistical
Concept Deoxycytidine
Concept Diabetes Mellitus
Concept Drug Screening Assays, Antitumor
Concept Follow-Up Studies
Concept Genetic Testing
Concept Longitudinal Studies
Concept Lymphocytes
Concept Omeprazole
Concept Prospective Studies
Concept Receptors, Antigen, T-Cell
Concept Retrospective Studies
Concept T-Lymphocytes
Concept Tramadol
Concept User-Computer Interface
Concept Vaccines, Synthetic
Concept Tumor Suppressor Protein p53
Concept Hospital Mortality
Concept Fenretinide
Concept E-Selectin
Concept Computational Biology
Concept Genetic Predisposition to Disease
Concept Genomics
Concept Polyomavirus Infections
Concept Chromosomes, Human, X
Concept Drug Recalls
Academic Article The role of chemotherapy in upper tract urothelial carcinoma.
Academic Article Renal medullary-like carcinoma in an adult without sickle cell hemoglobinopathy.
Academic Article Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy.
Academic Article Population differences in platinum toxicity as a means to identify novel genetic susceptibility variants.
Academic Article Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines.
Academic Article Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoietic stem cell transplant: reduced clearance at high doses and occurrence of late sinusoidal obstruction syndrome/veno-occlusive disease.
Academic Article Evaluating the activity of temsirolimus in neuroendocrine cancer.
Academic Article A phase I study of continuous infusion cilengitide in patients with solid tumors.
Academic Article Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients.
Academic Article BK virus infection is associated with hematuria and renal impairment in recipients of allogeneic hematopoetic stem cell transplants.
Academic Article Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation.
Academic Article Pharmacogenomics in early-phase oncology clinical trials: is there a sweet spot in phase II?
Academic Article Bladder cancer pharmacogenomics: recent insights and future perspectives.
Academic Article Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity.
Academic Article The 1200 patients project: creating a new medical model system for clinical implementation of pharmacogenomics.
Academic Article Germline pharmacogenomics in oncology: decoding the patient for targeting therapy.
Academic Article Population differences in the rate of proliferation of international HapMap cell lines.
Academic Article Editorial comment.
Academic Article Efficacy and toxicity of sunitinib in patients with metastatic renal cell carcinoma with severe renal impairment or on haemodialysis.
Academic Article Clinicopathologic features of late-onset veno-occlusive disease/sinusoidal obstruction syndrome after high dose intravenous busulfan and hematopoietic cell transplant.
Academic Article Identification of novel germline polymorphisms governing capecitabine sensitivity.
Academic Article Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers.
Academic Article A randomized, phase II study of pazopanib in castrate-sensitive prostate cancer: a University of Chicago Phase II Consortium/Department of Defense Prostate Cancer Clinical Trials Consortium study.
Academic Article Time from prior chemotherapy enhances prognostic risk grouping in the second-line setting of advanced urothelial carcinoma: a retrospective analysis of pooled, prospective phase 2 trials.
Academic Article Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations.
Academic Article 12th Annual meeting of the Society of Urologic Oncology (SUO) bladder cancer sessions I and II summary report.
Academic Article Implementing genomic medicine in the clinic: the future is here.
Academic Article Critical analysis of contemporary clinical research in muscle-invasive and metastatic urothelial cancer: a report from the Bladder Cancer Advocacy Network Clinical Trials Working Group.
Academic Article A nomogram including baseline prognostic factors to estimate the activity of second-line therapy for advanced urothelial carcinoma.
Academic Article N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes.
Academic Article Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival.
Academic Article Institutional Profile: University of Chicago Center for Personalized Therapeutics: research, education and implementation science.
Academic Article Adoption of a clinical pharmacogenomics implementation program during outpatient care--initial results of the University of Chicago "1,200 Patients Project".
Academic Article Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
Academic Article Clofarabine-associated acute kidney injury in patients undergoing hematopoietic stem cell transplant.
Academic Article Unleashing the power of preemptive pharmacogenomics.
Academic Article Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs.
Academic Article Differential role of an NF-?B transcriptional response element in endothelial versus intimal cell VCAM-1 expression.
Academic Article Pharmacogenomics and cardiology: improving treatment with existing drugs.
Academic Article Serum C-Telopeptide Collagen Crosslinks and Plasma Soluble VEGFR2 as Pharmacodynamic Biomarkers in a Trial of Sequentially Administered Sunitinib and Cilengitide.
Academic Article Case Report of a Rare Presentation of Urothelial Carcinoma With Gastric Metastasis.
Academic Article Saracatinib as a metastasis inhibitor in metastatic castration-resistant prostate cancer: A University of Chicago Phase 2 Consortium and DOD/PCF Prostate Cancer Clinical Trials Consortium Study.
Academic Article The Outlier in All of Us: Why Implementing Pharmacogenomics Could Matter for Everyone.
Academic Article Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial.
Academic Article Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
Academic Article Disease-drug database for pharmacogenomic-based prescribing.
Academic Article Safety and Efficacy of Durvalumab (MEDI4736), an Anti-Programmed Cell Death Ligand-1 Immune Checkpoint Inhibitor, in Patients With Advanced Urothelial Bladder Cancer.
Academic Article Spectrum of genomic alterations in FGFR3: current appraisal of the potential role of FGFR3 in advanced urothelial carcinoma.
Academic Article Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a Pharmacodynamic Biomarker for Pazopanib in Metastatic Renal Carcinoma.
Academic Article Utility of patient-derived lymphoblastoid cell lines as an ex vivo capecitabine sensitivity prediction model for breast cancer patients.
Academic Article Clinical Evaluation of Cisplatin Sensitivity of Germline Polymorphisms in Neoadjuvant Chemotherapy for Urothelial Cancer.
Academic Article Patient Perceptions of Care as Influenced by a Large Institutional Pharmacogenomic Implementation Program.
Academic Article Safety and activity of pembrolizumab in patients with locally advanced or metastatic urothelial cancer (KEYNOTE-012): a non-randomised, open-label, phase 1b study.
Academic Article The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems.
Academic Article Phase I study of dose-escalated busulfan with fludarabine and alemtuzumab as conditioning for allogeneic hematopoetic stem cell transplantation (alloHCT).
Academic Article Assessment of patient perceptions of genomic testing to inform pharmacogenomic implementation.
Academic Article Pharmacogenomics-Based Point-of-Care Clinical Decision Support Significantly Alters Drug Prescribing.
Academic Article Analyzing the clinical actionability of germline pharmacogenomic findings in oncology.
Academic Article Low T-cell Receptor Diversity, High Somatic Mutation Burden, and High Neoantigen Load as Predictors of Clinical Outcome in Muscle-invasive Bladder Cancer.
Academic Article Efficacy and Safety of Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma: Updated Results From a Phase 1/2 Open-label Study.
Academic Article Atypical post-renal transplantation hyperparathyroidism--further support for "removing all enlarged glands".
Academic Article Long-term results of blood and marrow transplantation for Hodgkin's lymphoma.
Academic Article Simplifying the use of pharmacogenomics in clinical practice: Building the genomic prescribing system.
Academic Article Breaking Down Barriers to Effective Patient Care.
Academic Article Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy.
Academic Article Cyclophosphamide-based in vivo T-cell depletion for HLA-haploidentical transplantation in Fanconi anemia.
Academic Article Erratum to: Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of bladder carcinoma.
Academic Article Blood glucose control using a computer-guided glucose management system in allogeneic hematopoietic cell transplant recipients.
Academic Article First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 study.
Academic Article Safety and Efficacy of Hypofractionated Radiotherapy With Capecitabine in Elderly Patients With Urothelial Carcinoma.
Academic Article Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of bladder carcinoma.
Academic Article Assessment of provider-perceived barriers to clinical use of pharmacogenomics during participation in an institutional implementation study.
Academic Article Analysis of comprehensive pharmacogenomic profiling to impact in-hospital prescribing.
Academic Article Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes.
Academic Article Restructuring of the Diabetes Day Centre: a pilot lean project in a tertiary referral centre in the West of Ireland.
Academic Article The ACCOuNT Consortium: A Model for the Discovery, Translation, and Implementation of Precision Medicine in African Americans.
Academic Article Patient-provider communications about pharmacogenomic results increase patient recall of medication changes.
Academic Article Pivotal Trial of Enfortumab Vedotin in Urothelial Carcinoma After Platinum and Anti-Programmed Death 1/Programmed Death Ligand 1 Therapy.
Academic Article Pharmacogenomic considerations for medications in the perioperative setting.
Academic Article The ImPreSS Trial: Implementation of Point-of-Care Pharmacogenomic Decision Support in Perioperative Care.
Academic Article Assessment of Patient Knowledge and Perceptions of Pharmacogenomics Before and After Using a Mock Results Patient Web Portal.
Academic Article Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation.
Academic Article Patient-reported outcomes and inflammatory biomarkers in patients with locally advanced/metastatic urothelial carcinoma treated with durvalumab in phase 1/2 dose-escalation study 1108.
Academic Article Clonal Hematopoiesis in Related Allogeneic Transplant Donors: Implications for Screening and Management.
Academic Article Pharmacogenomic-Based Decision Support to Predict Adherence to Medications.
Academic Article Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015.
Academic Article Pembrolizumab as First-line Therapy in Cisplatin-ineligible Advanced Urothelial Cancer (KEYNOTE-052): Outcomes in Older Patients by Age and Performance Status.
Academic Article Long-Term Outcomes in KEYNOTE-052: Phase II Study Investigating First-Line Pembrolizumab in Cisplatin-Ineligible Patients With Locally Advanced or Metastatic Urothelial Cancer.
Academic Article CD8 lymphocytes in tumors and nonsynonymous mutational load correlate with prognosis of bladder cancer patients treated with immune checkpoint inhibitors.
Academic Article A randomized phase 2 trial of pembrolizumab versus pembrolizumab and acalabrutinib in patients with platinum-resistant metastatic urothelial cancer.
Academic Article TCC in Transplant Ureter--When and When Not to Preserve the Transplant Kidney.
Academic Article Incorporating preemptive pharmacogenomic testing into the clinical setting.
Academic Article Patient insights on features of an effective pharmacogenomics patient portal.
Academic Article Validation of an Extensive CYP2D6 Assay Panel Based on Invader and TaqMan Copy Number Assays.
Academic Article Implementation of pharmacogenomic testing in oncology care (PhOCus): study protocol of a pragmatic, randomized clinical trial.
Academic Article Impact and applicability of pharmacogenomics in rheumatology: an integrated analysis.
Academic Article Adjuvant atezolizumab versus observation in muscle-invasive urothelial carcinoma (IMvigor010): a multicentre, open-label, randomised, phase 3 trial.
Academic Article Enfortumab vedotin after PD-1 or PD-L1 inhibitors in cisplatin-ineligible patients with advanced urothelial carcinoma (EV-201): a multicentre, single-arm, phase 2 trial.
Academic Article EZR-ROS1 fusion renal cell carcinoma mimicking urothelial carcinoma: report of a previously undescribed gene fusion in renal cell carcinoma.
Academic Article Phase I Study of Stereotactic Body Radiotherapy plus Nivolumab and Urelumab or Cabiralizumab in Advanced Solid Tumors.
Academic Article Validation of a Large Custom-Designed Pharmacogenomics Panel on an Array Genotyping Platform.
Academic Article Appraisal and development of evidence-based clinical decision support to enable perioperative pharmacogenomic application.
Academic Article Impact of CYP2D6 Pharmacogenomic Status on Pain Control Among Opioid-Treated Oncology Patients.
Academic Article Creation of a pharmacogenomics patient portal complementary to an existing institutional provider-facing clinical decision support system.
Academic Article Anesthesia providers as stakeholders to adoption of pharmacogenomic information in perioperative care.
Academic Article Underrepresented patient views and perceptions of personalized medication treatment through pharmacogenomics.
Academic Article The Contribution of Pharmacogenetic Drug Interactions to 90-Day Hospital Readmissions: Preliminary Results from a Real-World Healthcare System.
Academic Article Applicability of Pharmacogenomically Guided Medication Treatment during Hospitalization of At-Risk Minority Patients.
Academic Article Clinically actionable genotypes for anticancer prescribing among >1500 patients with pharmacogenomic testing.
Academic Article Health-related Quality of Life of Patients with Locally Advanced or Metastatic Urothelial Cancer Treated with Enfortumab Vedotin after Platinum and PD-1/PD-L1 Inhibitor Therapy: Results from Cohort 1 of the Phase 2 EV-201 Clinical Trial.
Academic Article Pilot Findings of Pharmacogenomics in Perioperative Care: Initial Results From the First Phase of the ImPreSS Trial.
Academic Article Putative Biomarkers of Clinical Benefit With Pembrolizumab in Advanced Urothelial Cancer: Results from the KEYNOTE-045 and KEYNOTE-052 Landmark Trials.
Academic Article Management of Dermatologic Events Associated With the Nectin-4-directed Antibody-Drug Conjugate Enfortumab Vedotin.
Academic Article Modern developments in germline pharmacogenomics for oncology prescribing.
Academic Article Antibody and T cell responses to COVID-19 vaccination in patients receiving anticancer therapies.
Academic Article Effect Modification by Social Determinants of Pharmacogenetic Medication Interactions on 90-Day Hospital Readmissions within an Integrated U.S. Healthcare System.
Academic Article In Reply.
Academic Article Efficacy and safety of pembrolizumab in metastatic urothelial carcinoma: results from KEYNOTE-045 and KEYNOTE-052 after up to 5 years of follow-up.
Academic Article Collaborative study from the Bladder Cancer Advocacy Network for the genomic analysis of metastatic urothelial cancer.
Academic Article Implementation of pharmacogenomics into inpatient general medicine.
Academic Article DPYD Testing: Time to Put Patient Safety First.
Concept Poly(ADP-ribose) Polymerase Inhibitors
Concept Capecitabine
Concept Patient Reported Outcome Measures
Concept Pharmacogenomic Testing
Concept Patient Portals
Concept Antineoplastic Agents, Immunological
Concept Netrin Receptors
Concept Alemtuzumab
Concept Nectins
Concept Tertiary Care Centers
Concept Prostatic Neoplasms, Castration-Resistant
Concept Glycoside Hydrolase Inhibitors
Academic Article Phase II Trial of Olaparib in Patients With Metastatic Urothelial Cancer Harboring DNA Damage Response Gene Alterations.
Academic Article Enfortumab Vedotin With or Without Pembrolizumab in Cisplatin-Ineligible Patients With Previously Untreated Locally Advanced or Metastatic Urothelial Cancer.
Academic Article Implementation of pharmacogenomics testing for precision medicine.
Academic Article Atezolizumab plus chemotherapy versus placebo plus chemotherapy in untreated locally advanced or metastatic urothelial carcinoma (IMvigor130): final overall survival analysis results from a randomised, controlled, phase 3 study.
Academic Article Patient-Reported Outcomes in Patients With Advanced Urothelial Cancer Who Are Ineligible for Cisplatin and Treated With First-Line Enfortumab Vedotin Alone or With Pembrolizumab.
Academic Article Bladder-Preserving Trimodality Therapy With Capecitabine.
Academic Article Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy.
Academic Article A phase I trial of enzalutamide plus selective glucocorticoid receptor modulator relacorilant in patients with metastatic castration resistant prostate cancer.
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