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Weichselbaum, Ralph R.
One or more keywords matched the following items that are connected to Weichselbaum, Ralph R.
Item TypeName
Concept Alleles
Concept Amino Acid Sequence
Concept Base Sequence
Concept Genes, Regulator
Concept Gene Expression Regulation
Concept Genes, Dominant
Concept Genes, Viral
Concept Gene Conversion
Concept Genes
Concept Genes, Recessive
Concept Oncogenes
Concept Gene Amplification
Concept Multigene Family
Concept Molecular Sequence Data
Concept Sequence Homology, Nucleic Acid
Concept Genes, ras
Concept Sequence Homology, Amino Acid
Concept Gene Rearrangement
Concept Genes, Essential
Concept Genes, BRCA2
Concept Genes, Tumor Suppressor
Concept Genes, jun
Concept Gene Expression
Concept Genes, Retinoblastoma
Concept Genes, Immediate-Early
Concept Gene Transfer Techniques
Concept Gene Deletion
Concept Transgenes
Concept Genes, MDR
Concept Gene Regulatory Networks
Concept src Homology Domains
Concept Gene Knockout Techniques
Concept Genes, BRCA1
Concept Gene Expression Profiling
Concept Genes, myc
Concept Genome, Human
Concept Gene Expression Regulation, Viral
Concept Gene Expression Regulation, Enzymologic
Concept Gene Expression Regulation, Leukemic
Concept Genes, p53
Concept Genes, fos
Concept Genes, myb
Concept Gene Silencing
Concept Gene Knockdown Techniques
Concept Gene Targeting
Concept Protein Sorting Signals
Concept Transcriptome
Concept Genes, Neoplasm
Concept Proto-Oncogenes
Concept Gene Expression Regulation, Neoplastic
Concept Conserved Sequence
Academic Article Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
Academic Article Attenuation of G2-phase cell cycle checkpoint control is associated with increased frequencies of unrejoined chromosome breaks in human tumor cells.
Academic Article C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure.
Academic Article Ionizing radiation down-regulates histone H1 gene expression by transcriptional and post-transcriptional mechanisms.
Academic Article p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.
Academic Article Phorbol ester-induced monocytic differentiation is associated with G2 delay and down-regulation of cdc25 expression.
Academic Article Footprinting of individual tumors and their variants by constitutive cytokine expression patterns.
Academic Article Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor.
Academic Article Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation.
Academic Article Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
Academic Article Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis.
Academic Article Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature.
Academic Article Down-regulation of cell cycle control genes by ionizing radiation.
Academic Article Prolonged c-jun expression in irradiated ataxia telangiectasia fibroblasts.
Academic Article Differentiation and retrodifferentiation of human myeloid leukemia cells is associated with reversible induction of cell cycle-regulatory genes.
Academic Article Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors.
Academic Article Involvement of reactive oxygen intermediates in the induction of c-jun gene transcription by ionizing radiation.
Academic Article In vivo replication-deficient adenovirus vector-mediated transduction of the cytosine deaminase gene sensitizes glioma cells to 5-fluorocytosine.
Academic Article Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts.
Academic Article Human papillomavirus expression and p53 gene mutations in squamous cell carcinoma.
Academic Article Radiogenetic therapy: on the interaction of viral therapy and ionizing radiation for improving local control of tumors.
Academic Article Regulation of Rad51 function by c-Abl in response to DNA damage.
Academic Article Thymidylate synthase expression and response to neoadjuvant chemotherapy in patients with advanced head and neck cancer.
Academic Article The essential functions of human Rad51 are independent of ATP hydrolysis.
Academic Article Strategies for enhancing viral-based gene therapy using ionizing radiation.
Academic Article Determination of cell fate by c-Abl activation in the response to DNA damage.
Academic Article Gene therapy of cancer.
Academic Article Replication-competent, nonneuroinvasive genetically engineered herpes virus is highly effective in the treatment of therapy-resistant experimental human tumors.
Academic Article Role of gene therapy in radiation oncology.
Academic Article p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.
Academic Article Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
Academic Article Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Academic Article Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
Academic Article Radiation-inducible gene therapy.
Academic Article Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
Academic Article Molecular targeting of gene therapy and radiotherapy.
Academic Article Gene therapy enhances the antiproliferative effect of radiation in intimal hyperplasia.
Academic Article Quantitative analysis of DNA array autoradiographs.
Academic Article TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene.
Academic Article Prospects for viral-based strategies enhancing the anti-tumor effects of ionizing radiation.
Academic Article Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.
Academic Article cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.
Academic Article Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma.
Academic Article Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors.
Academic Article Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
Academic Article The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin.
Academic Article Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process.
Academic Article The role of cdc2 in the expression of herpes simplex virus genes.
Academic Article Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model.
Academic Article The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma.
Academic Article Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
Academic Article Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV).
Academic Article Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.
Academic Article Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells.
Academic Article Transcriptional control of viral gene therapy by cisplatin.
Academic Article Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor.
Academic Article Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.
Academic Article Control of gene therapy by MDR1 and EGR1 promoter sequences in transcriptional targeting by chemotherapy (Review).
Academic Article Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy.
Academic Article Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology.
Academic Article Prevention of restenosis by a herpes simplex virus mutant capable of controlled long-term expression in vascular tissue in vivo.
Academic Article Endothelial cells co-cultured with wild-type and dominant/negative p53-transfected glioblastoma cells exhibit differential sensitivity to radiation-induced apoptosis.
Academic Article Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay.
Academic Article Two prostate carcinoma cell lines demonstrate abnormalities in tumor suppressor genes.
Academic Article Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation.
Academic Article Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines.
Academic Article Possible applications of biotechnology to radiotherapy.
Academic Article Biological consequences of gene regulation after ionizing radiation exposure.
Academic Article Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
Academic Article Interaction of amifostine and ionizing radiation on transcriptional patterns of apoptotic genes expressed in human microvascular endothelial cells (HMEC).
Academic Article Ionizing radiation: a genetic switch for cancer therapy.
Academic Article Gene therapy: the challenges of translating laboratory research into clinical practice.
Academic Article Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.
Academic Article Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
Academic Article Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
Academic Article Ionizing radiation regulates expression of the c-jun protooncogene.
Academic Article TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors.
Academic Article An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer.
Academic Article p53 gene mutations and abnormal retinoblastoma protein in radiation-induced human sarcomas.
Academic Article MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer.
Academic Article Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.
Academic Article Chemo-inducible gene therapy.
Academic Article Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.
Academic Article Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers.
Academic Article Characterization of response to radiation mediated gene therapy by means of multimodality imaging.
Academic Article MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients.
Academic Article Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression.
Academic Article Vascular endothelial growth factor pathway.
Academic Article STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.
Academic Article Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
Academic Article Increased oncolytic efficacy for high-grade gliomas by optimal integration of ionizing radiation into the replicative cycle of HSV-1.
Academic Article Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.
Academic Article MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment.
Academic Article Sensitivities of NIH/3T3-derived clonal cell lines to ionizing radiation: significance for gene transfer studies.
Academic Article Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
Academic Article Southern analysis of human head and neck cancer cells for homologous sequences using yeast gamma repair genes.
Academic Article Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines.
Academic Article Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression.
Academic Article Chromosome 13 homozygosity in osteosarcoma without retinoblastoma.
Academic Article An important step in radiation carcinogenesis may be inactivation of cellular genes.
Academic Article Some retinoblastomas, osteosarcomas, and soft tissue sarcomas may share a common etiology.
Academic Article Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer.
Academic Article Effect of Bcl-2 on ionizing radiation and 1-beta-D-arabinofuranosylcytosine-induced internucleosomal DNA fragmentation and cell survival in human myeloid leukemia cells.
Academic Article Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.
Academic Article Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner.
Academic Article Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
Academic Article Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response.
Academic Article Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.
Academic Article Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.
Academic Article Ionizing radiation activates transcription of the EGR1 gene via CArG elements.
Academic Article Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy.
Academic Article Spatial and temporal control of gene therapy using ionizing radiation.
Academic Article Ketoconazole attenuates radiation-induction of tumor necrosis factor.
Academic Article Radiation induction of immediate early genes: effectors of the radiation-stress response.
Academic Article Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.
Academic Article Gene therapy targeted by ionizing radiation.
Academic Article Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
Academic Article Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
Academic Article Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.
Academic Article Molecular targets to overcome radioresistance.
Academic Article Human papilloma virus and p53 in head and neck cancer: clinical correlates and survival.
Academic Article Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer.
Academic Article The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes.
Academic Article Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma.
Academic Article Friendly fire: redirecting herpes simplex virus-1 for therapeutic applications.
Academic Article Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
Academic Article Regulation of tumor necrosis factor gene expression by ionizing radiation in human myeloid leukemia cells and peripheral blood monocytes.
Academic Article Monosomy 12p in a radiation-induced germ cell tumor.
Academic Article Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis.
Academic Article Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
Academic Article MicroRNA expression characterizes oligometastasis(es).
Academic Article Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer.
Academic Article Expression and methylation of the Blym gene in human tumor cell lines.
Academic Article p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
Academic Article DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site.
Academic Article Modulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK.
Academic Article Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas.
Academic Article DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.
Academic Article Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs.
Academic Article Poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer.
Academic Article DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.
Academic Article Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.
Academic Article 14q32-encoded microRNAs mediate an oligometastatic phenotype.
Academic Article Imaging of tumor clones with differential liver colonization.
Academic Article MUC1-C activates the TAK1 inflammatory pathway in colon cancer.
Academic Article Protection from Radiation-Induced Pulmonary Fibrosis by Peripheral Targeting of Cannabinoid Receptor-1.
Academic Article Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article Clinical and molecular markers of long-term survival after oligometastasis-directed stereotactic body radiotherapy (SBRT).
Academic Article MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation.
Academic Article Very low doses of ionizing radiation and redox associated modifiers affect survivin-associated changes in radiation sensitivity.
Academic Article Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers.
Academic Article Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance.
Academic Article Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma.
Academic Article CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.
Academic Article Low Recombination Proficiency Score (RPS) Predicts Heightened Sensitivity to DNA-Damaging Chemotherapy in Breast Cancer.
Academic Article Systemic delivery of the tumor necrosis factor gene to tumors by a novel dual DNA-nanocomplex in a nanoparticle system.
Academic Article In Vivo Delivery and Therapeutic Effects of a MicroRNA on Colorectal Liver Metastases.
Academic Article BCL3 expression promotes resistance to alkylating chemotherapy in gliomas.
Academic Article A Critical Role of the IL-1ß-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis.
Academic Article Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis.
Academic Article ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response.
Academic Article TP53 Mutational Status and ROS Effect the Expression of the Survivin-Associated Radio-Adaptive Response.
Academic Article DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs.
Academic Article Molecular Classification of Lymph Node Metastases Subtypes Predict for Survival in Head and Neck Cancer.
Academic Article Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma.
Academic Article Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer.
Academic Article Tumor-reprogrammed resident T cells resist radiation to control tumors.
Academic Article Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Academic Article Improved Survival Associated with Local Tumor Response Following Multisite Radiotherapy and Pembrolizumab: Secondary Analysis of a Phase I Trial.
Academic Article RIG-I-Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy.
Academic Article The Change of Soluble Programmed Cell Death-Ligand 1 in Glioma Patients Receiving Radiotherapy and Its Impact on Clinical Outcomes.
Academic Article CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma.
Academic Article The relationship between expression of PD-L1 and HIF-1a in glioma cells under hypoxia.
Academic Article YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
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