 Binding Sites
"Binding Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
| Descriptor ID |
D001665
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| MeSH Number(s) |
G02.111.570.120
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| Concept/Terms |
Binding Sites- Binding Sites
- Site, Binding
- Sites, Binding
- Binding Site
- Combining Site
- Combining Sites
- Site, Combining
- Sites, Combining
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Below are MeSH descriptors whose meaning is more general than "Binding Sites".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites".
This graph shows the total number of publications written about "Binding Sites" by people in this website by year, and whether "Binding Sites" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 4 | 4 | | 1981 | 0 | 2 | 2 | | 1982 | 0 | 4 | 4 | | 1983 | 0 | 6 | 6 | | 1984 | 0 | 2 | 2 | | 1985 | 0 | 4 | 4 | | 1986 | 0 | 3 | 3 | | 1987 | 0 | 2 | 2 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 7 | 7 | | 1990 | 0 | 10 | 10 | | 1991 | 0 | 8 | 8 | | 1992 | 0 | 16 | 16 | | 1993 | 0 | 22 | 22 | | 1994 | 0 | 20 | 20 | | 1995 | 0 | 25 | 25 | | 1996 | 0 | 23 | 23 | | 1997 | 0 | 18 | 18 | | 1998 | 1 | 29 | 30 | | 1999 | 0 | 31 | 31 | | 2000 | 0 | 28 | 28 | | 2001 | 0 | 28 | 28 | | 2002 | 0 | 39 | 39 | | 2003 | 0 | 43 | 43 | | 2004 | 0 | 38 | 38 | | 2005 | 1 | 32 | 33 | | 2006 | 0 | 33 | 33 | | 2007 | 0 | 35 | 35 | | 2008 | 0 | 27 | 27 | | 2009 | 0 | 26 | 26 | | 2010 | 3 | 32 | 35 | | 2011 | 2 | 29 | 31 | | 2012 | 0 | 36 | 36 | | 2013 | 0 | 40 | 40 | | 2014 | 3 | 26 | 29 | | 2015 | 0 | 27 | 27 | | 2016 | 0 | 30 | 30 | | 2017 | 0 | 20 | 20 | | 2018 | 0 | 29 | 29 | | 2019 | 1 | 15 | 16 | | 2020 | 0 | 21 | 21 | | 2021 | 0 | 11 | 11 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Binding Sites" by people in Profiles.
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Baxa MC, Sosnick TR. Engineered Metal-Binding Sites to Probe Protein Folding Transition States: Psi Analysis. Methods Mol Biol. 2022; 2376:31-63.
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Pan M, Zheng Q, Wang T, Liang L, Mao J, Zuo C, Ding R, Ai H, Xie Y, Si D, Yu Y, Liu L, Zhao M. Structural insights into Ubr1-mediated N-degron polyubiquitination. Nature. 2021 12; 600(7888):334-338.
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Borowska MT, Drees C, Yarawsky AE, Viswanathan M, Ryan SM, Bunker JJ, Herr AB, Bendelac A, Adams EJ. The molecular characterization of antibody binding to a superantigen-like protein from a commensal microbe. Proc Natl Acad Sci U S A. 2021 09 28; 118(39).
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Gupta Y, Kumar S, Zak SE, Jones KA, Upadhyay C, Sharma N, Azizi SA, Kathayat RS. Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach. Bioorg Med Chem. 2021 10 01; 47:116393.
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Chen Q, Plasencia M, Li Z, Mukherjee S, Patra D, Chen CL, Klose T, Yao XQ, Kossiakoff AA, Chang L, Andrews PC, Tesmer JJG. Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature. 2021 07; 595(7868):600-605.
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Pan T, Dan Y, Guo D, Jiang J, Ran D, Zhang L, Tian B, Yuan J, Yu Y, Gan Z. Discovery of 2,4-pyrimidinediamine derivatives as potent dual inhibitors of ALK and HDAC. Eur J Med Chem. 2021 Nov 15; 224:113672.
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Michalska K, Wellington S, Maltseva N, Jedrzejczak R, Selem-Mojica N, Rosas-Becerra LR, Barona-Gómez F, Hung DT, Joachimiak A. Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB. Protein Sci. 2021 09; 30(9):1904-1918.
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Cater RJ, Chua GL, Erramilli SK, Keener JE, Choy BC, Tokarz P, Chin CF, Quek DQY, Kloss B, Pepe JG, Parisi G, Wong BH, Clarke OB, Marty MT, Kossiakoff AA, Khelashvili G, Silver DL, Mancia F. Structural basis of omega-3 fatty acid transport across the blood-brain barrier. Nature. 2021 07; 595(7866):315-319.
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Amobi-McCloud A, Muthuswamy R, Battaglia S, Yu H, Liu T, Wang J, Putluri V, Singh PK, Qian F, Huang RY, Putluri N, Tsuji T, Lugade AA, Liu S, Odunsi K. IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation. Front Immunol. 2021; 12:678999.
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Voce DJ, Bernal GM, Cahill KE, Wu L, Mansour N, Crawley CD, Campbell PS, Arina A, Weichselbaum RR, Yamini B. CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma. Sci Rep. 2021 03 11; 11(1):5665.
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