 Binding Sites
"Binding Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
| Descriptor ID |
D001665
|
| MeSH Number(s) |
G02.111.570.120
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| Concept/Terms |
Binding Sites- Binding Sites
- Site, Binding
- Sites, Binding
- Binding Site
- Combining Site
- Combining Sites
- Site, Combining
- Sites, Combining
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Below are MeSH descriptors whose meaning is more general than "Binding Sites".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites".
This graph shows the total number of publications written about "Binding Sites" by people in this website by year, and whether "Binding Sites" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 4 | 4 | | 1981 | 0 | 2 | 2 | | 1982 | 0 | 4 | 4 | | 1983 | 0 | 6 | 6 | | 1984 | 0 | 2 | 2 | | 1985 | 0 | 4 | 4 | | 1986 | 0 | 3 | 3 | | 1987 | 0 | 2 | 2 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 7 | 7 | | 1990 | 0 | 10 | 10 | | 1991 | 0 | 8 | 8 | | 1992 | 0 | 16 | 16 | | 1993 | 0 | 22 | 22 | | 1994 | 0 | 20 | 20 | | 1995 | 0 | 25 | 25 | | 1996 | 0 | 25 | 25 | | 1997 | 0 | 18 | 18 | | 1998 | 1 | 29 | 30 | | 1999 | 0 | 31 | 31 | | 2000 | 0 | 28 | 28 | | 2001 | 0 | 28 | 28 | | 2002 | 0 | 39 | 39 | | 2003 | 0 | 42 | 42 | | 2004 | 0 | 38 | 38 | | 2005 | 1 | 34 | 35 | | 2006 | 0 | 33 | 33 | | 2007 | 0 | 34 | 34 | | 2008 | 0 | 27 | 27 | | 2009 | 0 | 25 | 25 | | 2010 | 3 | 30 | 33 | | 2011 | 2 | 29 | 31 | | 2012 | 0 | 36 | 36 | | 2013 | 0 | 39 | 39 | | 2014 | 3 | 26 | 29 | | 2015 | 0 | 27 | 27 | | 2016 | 0 | 30 | 30 | | 2017 | 0 | 20 | 20 | | 2018 | 0 | 25 | 25 | | 2019 | 1 | 13 | 14 | | 2020 | 0 | 9 | 9 |
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Below are the most recent publications written about "Binding Sites" by people in Profiles.
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Wu L, Crawley CD, Garofalo A, Nichols JW, Campbell PA, Khramtsova GF, Olopade OI, Weichselbaum RR, Yamini B. p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability. Nat Commun. 2020 10 06; 11(1):5007.
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Binas O, Tants JN, Peter SA, Janowski R, Davydova E, Braun J, Niessing D, Schwalbe H, Weigand JE, Schlundt A. Structural basis for the recognition of transiently structured AU-rich elements by Roquin. Nucleic Acids Res. 2020 07 27; 48(13):7385-7403.
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Kumar A, Basak S, Rao S, Gicheru Y, Mayer ML, Sansom MSP, Chakrapani S. Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nat Commun. 2020 07 27; 11(1):3752.
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Clark MD, Contreras GF, Shen R, Perozo E. Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1. Nature. 2020 07; 583(7814):145-149.
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Pillai AS, Chandler SA, Liu Y, Signore AV, Cortez-Romero CR, Benesch JLP, Laganowsky A, Storz JF, Hochberg GKA, Thornton JW. Origin of complexity in haemoglobin evolution. Nature. 2020 05; 581(7809):480-485.
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Li J, Xie Y, Cornelius S, Jiang X, Sando R, Kordon SP, Pan M, Leon K, Südhof TC, Zhao M, Araç D. Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism. Nat Commun. 2020 05 01; 11(1):2140.
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Ikegami K, Secchia S, Almakki O, Lieb JD, Moskowitz IP. Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria. Dev Cell. 2020 03 23; 52(6):699-713.e11.
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Leon K, Cunningham RL, Riback JA, Feldman E, Li J, Sosnick TR, Zhao M, Monk KR, Araç D. Structural basis for adhesion G protein-coupled receptor Gpr126 function. Nat Commun. 2020 01 10; 11(1):194.
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MacKerell AD, Jo S, Lakkaraju SK, Lind C, Yu W. Identification and characterization of fragment binding sites for allosteric ligand design using the site identification by ligand competitive saturation hotspots approach (SILCS-Hotspots). Biochim Biophys Acta Gen Subj. 2020 04; 1864(4):129519.
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Zost SJ, Lee J, Gumina ME, Parkhouse K, Henry C, Wu NC, Lee CD, Wilson IA, Wilson PC, Bloom JD, Hensley SE. Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans. Cell Rep. 2019 12 24; 29(13):4460-4470.e8.
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