"Binding, Competitive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.
| Descriptor ID |
D001667
|
| MeSH Number(s) |
E05.196.080 G02.111.084 G02.111.570.120.309
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Binding, Competitive".
Below are MeSH descriptors whose meaning is more specific than "Binding, Competitive".
This graph shows the total number of publications written about "Binding, Competitive" by people in this website by year, and whether "Binding, Competitive" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 6 | 6 |
| 1995 | 0 | 5 | 5 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 4 | 4 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 5 | 5 |
| 2002 | 0 | 7 | 7 |
| 2003 | 0 | 6 | 6 |
| 2005 | 0 | 5 | 5 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 6 | 6 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 2 | 2 |
| 2015 | 0 | 3 | 3 |
| 2016 | 0 | 4 | 4 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Binding, Competitive" by people in Profiles.
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Chaperones directly and efficiently disperse stress-triggered biomolecular condensates. Mol Cell. 2022 02 17; 82(4):741-755.e11.
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Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation. Mol Pharm. 2021 10 04; 18(10):3871-3881.
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High-resolution structures of multiple 5-HT3AR-setron complexes reveal a novel mechanism of competitive inhibition. Elife. 2020 10 16; 9.
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Evaluation of a New Generation Automated Assay for 25-Hydroxy Vitamin D Based on Competitive Protein Binding. J Appl Lab Med. 2019 09; 4(2):247-253.
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sNASP and ASF1A function through both competitive and compatible modes of histone binding. Nucleic Acids Res. 2017 01 25; 45(2):643-656.
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Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus. Proc Natl Acad Sci U S A. 2016 10 18; 113(42):11931-11936.
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Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen. Nucleic Acids Res. 2016 Nov 16; 44(20):9565-9577.
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Internetwork competition for monomers governs actin cytoskeleton organization. Nat Rev Mol Cell Biol. 2016 12; 17(12):799-810.
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FliW antagonizes CsrA RNA binding by a noncompetitive allosteric mechanism. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):9870-5.
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DNA-binding sequence specificity of DUX4. Skelet Muscle. 2016; 6:8.