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Raymond E Moellering

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentChemistry
AddressChicago IL 60637
Email
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Montgomery JE, Moellering RE. Diels-Alder Cycloadditions for Peptide Macrocycle Formation. Methods Mol Biol. 2022; 2371:159-174. PMID: 34596848.
      View in: PubMed
    2. Coukos JS, Moellering RE. Methylglyoxal Forms Diverse Mercaptomethylimidazole Crosslinks with Thiol and Guanidine Pairs in Endogenous Metabolites and Proteins. ACS Chem Biol. 2021 11 19; 16(11):2453-2461. PMID: 34581579.
      View in: PubMed
    3. Huang JX, Wu D, Stein BD, Moellering RE. Huang et al. reply. Nat Methods. 2021 07; 18(7):763-767. PMID: 34140701.
      View in: PubMed
    4. Huang JX, Coukos JS, Moellering RE. Corrigendum to "Interaction profiling methods to map protein and pathway targets of bioactive ligands", [Curr Opin Chem Biol 54 (February 2020) 76-84]. Curr Opin Chem Biol. 2021 Aug; 63:230. PMID: 33223432.
      View in: PubMed
    5. Speltz TE, Moellering RE. Protein targeting with SAF(er) electrophiles. Nat Chem. 2020 10; 12(10):885-887. PMID: 32978603.
      View in: PubMed
    6. Chang JW, Bhuiyan M, Tsai HM, Zhang HJ, Li G, Fathi S, McCutcheon DC, Leoni L, Freifelder R, Chen CT, Moellering RE. In Vivo Imaging of the Tumor-Associated Enzyme NCEH1 with a Covalent PET Probe. Angew Chem Int Ed Engl. 2020 08 24; 59(35):15161-15165. PMID: 32415874.
      View in: PubMed
    7. Huang JX, Coukos JS, Moellering RE. Interaction profiling methods to map protein and pathway targets of bioactive ligands. Curr Opin Chem Biol. 2020 02; 54:76-84. PMID: 32146330.
      View in: PubMed
    8. Moellering RE. Editorial Overview: Tracking the ties that bind: Emerging technologies to profile biomolecular interactions in native environments. Curr Opin Chem Biol. 2020 02; 54:A1-A4. PMID: 32245537.
      View in: PubMed
    9. McCutcheon DC, Lee G, Carlos A, Montgomery JE, Moellering RE. Photoproximity Profiling of Protein-Protein Interactions in Cells. J Am Chem Soc. 2020 01 08; 142(1):146-153. PMID: 31820968.
      View in: PubMed
    10. Li G, Eckert MA, Chang JW, Montgomery JE, Chryplewicz A, Lengyel E, Moellering RE. Ultrasensitive, multiplexed chemoproteomic profiling with soluble activity-dependent proximity ligation. Proc Natl Acad Sci U S A. 2019 10 22; 116(43):21493-21500. PMID: 31591248.
      View in: PubMed
    11. Montgomery JE, Donnelly JA, Fanning SW, Speltz TE, Shangguan X, Coukos JS, Greene GL, Moellering RE. Versatile Peptide Macrocyclization with Diels-Alder Cycloadditions. J Am Chem Soc. 2019 10 16; 141(41):16374-16381. PMID: 31523967.
      View in: PubMed
    12. Huang JX, Lee G, Cavanaugh KE, Chang JW, Gardel ML, Moellering RE. High throughput discovery of functional protein modifications by Hotspot Thermal Profiling. Nat Methods. 2019 09; 16(9):894-901. PMID: 31384043.
      View in: PubMed
    13. Chang JW, Moellering RE. No Bones About It: Small Molecules for Bone Regeneration. Cell Chem Biol. 2019 07 18; 26(7):911-912. PMID: 31323220.
      View in: PubMed
    14. Li G, Moellering RE. Chemical probes for spatially resolved measurement of active enzymes in single cells. Methods Enzymol. 2019; 628:243-262. PMID: 31668232.
      View in: PubMed
    15. Li G, Moellering RE. A Concise, Modular Antibody-Oligonucleotide Conjugation Strategy Based on Disuccinimidyl Ester Activation Chemistry. Chembiochem. 2019 06 14; 20(12):1599-1605. PMID: 30767357.
      View in: PubMed
    16. Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaženovic I, Lastra RR, Curtis M, Yamada SD, Perets R, McGregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel E. Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts. Nature. 2019 05; 569(7758):723-728. PMID: 31043742.
      View in: PubMed
    17. Chang JW, Montgomery JE, Lee G, Moellering RE. Chemoproteomic Profiling of Phosphoaspartate Modifications in Prokaryotes. Angew Chem Int Ed Engl. 2018 11 26; 57(48):15712-15716. PMID: 30231186.
      View in: PubMed
    18. Bollong MJ, Lee G, Coukos JS, Yun H, Zambaldo C, Chang JW, Chin EN, Ahmad I, Chatterjee AK, Lairson LL, Schultz PG, Moellering RE. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. 2018 10; 562(7728):600-604. PMID: 30323285.
      View in: PubMed
    19. Yang H, Swartz AM, Park HJ, Srivastava P, Ellis-Guardiola K, Upp DM, Lee G, Belsare K, Gu Y, Zhang C, Moellering RE, Lewis JC. Evolving artificial metalloenzymes via random mutagenesis. Nat Chem. 2018 03; 10(3):318-324. PMID: 29461523.
      View in: PubMed
    20. Li G, Montgomery JE, Eckert MA, Chang JW, Tienda SM, Lengyel E, Moellering RE. An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells. Nat Commun. 2017 11 24; 8(1):1775. PMID: 29176560.
      View in: PubMed
    21. KleinJan A, Tindemans I, Montgomery JE, Lukkes M, de Bruijn MJW, van Nimwegen M, Bergen I, Moellering RE, Hoogsteden HC, Boon L, Amsen D, Hendriks RW. The Notch pathway inhibitor stapled a-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma. J Allergy Clin Immunol. 2018 07; 142(1):76-85.e8. PMID: 29111218.
      View in: PubMed
    22. Mitra S, Montgomery JE, Kolar MJ, Li G, Jeong KJ, Peng B, Verdine GL, Mills GB, Moellering RE. Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer. Nat Commun. 2017 09 22; 8(1):660. PMID: 28939823.
      View in: PubMed
    23. Chang JW, Lee G, Coukos JS, Moellering RE. Profiling Reactive Metabolites via Chemical Trapping and Targeted Mass Spectrometry. Anal Chem. 2016 07 05; 88(13):6658-61. PMID: 27314642.
      View in: PubMed
    24. Moellering RE, Cravatt BF. Functional lysine modification by an intrinsically reactive primary glycolytic metabolite. Science. 2013 Aug 02; 341(6145):549-53. PMID: 23908237.
      View in: PubMed
    25. Grossmann TN, Yeh JT, Bowman BR, Chu Q, Moellering RE, Verdine GL. Inhibition of oncogenic Wnt signaling through direct targeting of ß-catenin. Proc Natl Acad Sci U S A. 2012 Oct 30; 109(44):17942-7. PMID: 23071338.
      View in: PubMed
    26. Moellering RE, Cravatt BF. How chemoproteomics can enable drug discovery and development. Chem Biol. 2012 Jan 27; 19(1):11-22. PMID: 22284350.
      View in: PubMed
    27. Chang JW, Moellering RE, Cravatt BF. An activity-based imaging probe for the integral membrane hydrolase KIAA1363. Angew Chem Int Ed Engl. 2012 Jan 23; 51(4):966-70. PMID: 22162147.
      View in: PubMed
    28. Moellering RE, Cornejo M, Davis TN, Del Bianco C, Aster JC, Blacklow SC, Kung AL, Gilliland DG, Verdine GL, Bradner JE. Direct inhibition of the NOTCH transcription factor complex. Nature. 2009 Nov 12; 462(7270):182-8. PMID: 19907488.
      View in: PubMed
    29. Moellering RE, Black KC, Krishnamurty C, Baggett BK, Stafford P, Rain M, Gatenby RA, Gillies RJ. Acid treatment of melanoma cells selects for invasive phenotypes. Clin Exp Metastasis. 2008; 25(4):411-25. PMID: 18301995.
      View in: PubMed
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