 Lobeline
"Lobeline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid that has actions similar to NICOTINE on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
| Descriptor ID |
D008120
|
| MeSH Number(s) |
D03.132.478 D03.383.621.418
|
| Concept/Terms |
Smokeless- Smokeless
- Inibsa Brand of Lobelin Sulfate
|
Below are MeSH descriptors whose meaning is more general than "Lobeline".
Below are MeSH descriptors whose meaning is more specific than "Lobeline".
This graph shows the total number of publications written about "Lobeline" by people in this website by year, and whether "Lobeline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Lobeline" by people in Profiles.
-
Mohammad Hosseini Naveh Z, Malliavin TE, Maragliano L, Cottone G, Ciccotti G. Conformational changes in acetylcholine binding protein investigated by temperature accelerated molecular dynamics. PLoS One. 2014; 9(2):e88555.
-
Meyer AC, Neugebauer NM, Zheng G, Crooks PA, Dwoskin LP, Bardo MT. Effects of VMAT2 inhibitors lobeline and GZ-793A on methamphetamine-induced changes in dopamine release, metabolism and synthesis in vivo. J Neurochem. 2013 Oct; 127(2):187-98.
-
Neugebauer NM, Harrod SB, Stairs DJ, Crooks PA, Dwoskin LP, Bardo MT. Lobelane decreases methamphetamine self-administration in rats. Eur J Pharmacol. 2007 Sep 24; 571(1):33-8.
-
Miller DK, Lever JR, Rodvelt KR, Baskett JA, Will MJ, Kracke GR. Lobeline, a potential pharmacotherapy for drug addiction, binds to mu opioid receptors and diminishes the effects of opioid receptor agonists. Drug Alcohol Depend. 2007 Jul 10; 89(2-3):282-91.
-
Polston JE, Cunningham CS, Rodvelt KR, Miller DK. Lobeline augments and inhibits cocaine-induced hyperactivity in rats. Life Sci. 2006 Aug 01; 79(10):981-90.
-
Prabhakar NR, Mitra J, Overholt JL, Cherniack NS. Analysis of postinspiratory activity of phrenic motoneurons with chemical and vagal reflexes. J Appl Physiol (1985). 1986 Oct; 61(4):1499-509.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|