"Guanylate Cyclase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
| Descriptor ID |
D006162
|
| MeSH Number(s) |
D08.811.520.650.600 D12.644.360.350 D12.776.476.350
|
| Concept/Terms |
Guanylate Cyclase- Guanylate Cyclase
- Cyclase, Guanylate
- Guanyl Cyclase
- Cyclase, Guanyl
- Guanylyl Cyclase
- Cyclase, Guanylyl
- Inosinate Cyclase
- Cyclase, Inosinate
- Deoxyguanylate Cyclase
- Cyclase, Deoxyguanylate
|
Below are MeSH descriptors whose meaning is more general than "Guanylate Cyclase".
Below are MeSH descriptors whose meaning is more specific than "Guanylate Cyclase".
This graph shows the total number of publications written about "Guanylate Cyclase" by people in this website by year, and whether "Guanylate Cyclase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 4 | 0 | 4 |
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2014 | 3 | 0 | 3 |
| 2018 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanylate Cyclase" by people in Profiles.
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Microbiota-derived butyrate dampens linaclotide stimulation of the guanylate cyclase C pathway in patient-derived colonoids. Neurogastroenterol Motil. 2023 Dec; 35(12):e14681.
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T Cell Receptor-Regulated TGF-ß Type I Receptor Expression Determines T Cell Quiescence and Activation. Immunity. 2018 04 17; 48(4):745-759.e6.
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Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Clin Pharmacol Ther. 2015 Jan; 97(1):88-102.
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a1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders. Circ Cardiovasc Genet. 2014 Dec; 7(6):920-9.
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Inhibiting CARD11 translation during BCR activation by targeting the eIF4A RNA helicase. Blood. 2014 Dec 11; 124(25):3758-67.
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Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway. J Comp Neurol. 2009 Sep 01; 516(1):36-48.
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Nitroglycerin reperfusion reduces ischemia-reperfusion injury in non-heart-beating donor lungs. J Heart Lung Transplant. 2006 Jan; 25(1):110-9.
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G protein-coupled endothelial receptor for atypical cannabinoid ligands modulates a Ca2+-dependent K+ current. J Biol Chem. 2003 Nov 14; 278(46):46188-94.
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Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase. Am J Physiol Heart Circ Physiol. 2003 Aug; 285(2):H669-78.
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Guanylate cyclase activity and sperm function. Endocr Rev. 2002 Aug; 23(4):484-94.