Transforming Growth Factor beta
"Transforming Growth Factor beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
| Descriptor ID |
D016212
|
| MeSH Number(s) |
D12.644.276.374.687 D12.644.276.954.775 D12.776.467.374.687 D12.776.467.942.775 D23.529.374.687 D23.529.942.775
|
| Concept/Terms |
Transforming Growth Factor beta- Transforming Growth Factor beta
- Milk Growth Factor
- Factor, Milk Growth
- Growth Factor, Milk
- TGF-beta
- TGFbeta
- Platelet Transforming Growth Factor
- Bone-Derived Transforming Growth Factor
- Bone Derived Transforming Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta".
This graph shows the total number of publications written about "Transforming Growth Factor beta" by people in this website by year, and whether "Transforming Growth Factor beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 3 | 1 | 4 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 2 | 3 |
| 1997 | 4 | 4 | 8 |
| 1998 | 4 | 1 | 5 |
| 1999 | 3 | 2 | 5 |
| 2000 | 3 | 1 | 4 |
| 2001 | 6 | 7 | 13 |
| 2002 | 3 | 2 | 5 |
| 2003 | 5 | 5 | 10 |
| 2004 | 8 | 3 | 11 |
| 2005 | 5 | 11 | 16 |
| 2006 | 5 | 2 | 7 |
| 2007 | 5 | 3 | 8 |
| 2008 | 4 | 5 | 9 |
| 2009 | 6 | 4 | 10 |
| 2010 | 4 | 3 | 7 |
| 2011 | 9 | 5 | 14 |
| 2012 | 7 | 3 | 10 |
| 2013 | 3 | 5 | 8 |
| 2014 | 3 | 3 | 6 |
| 2015 | 2 | 7 | 9 |
| 2016 | 5 | 3 | 8 |
| 2017 | 3 | 4 | 7 |
| 2018 | 2 | 6 | 8 |
| 2019 | 2 | 7 | 9 |
| 2020 | 4 | 2 | 6 |
| 2021 | 0 | 5 | 5 |
| 2022 | 0 | 3 | 3 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta" by people in Profiles.
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Memory Precursors and Short-Lived Effector T cell Subsets Have Different Sensitivities to TGF?. Int J Mol Sci. 2023 Feb 15; 24(4).
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Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity. Cell Metab. 2022 10 04; 34(10):1486-1498.e7.
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RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling. Biochim Biophys Acta Rev Cancer. 2022 Sep; 1877(5):188803.
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CWHM-12, an Antagonist of Integrin-Mediated Transforming Growth Factor-Beta Activation Confers Protection During Early Mycobacterium tuberculosis Infection in Mice. J Interferon Cytokine Res. 2022 08; 42(8):421-429.
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Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment. Nat Metab. 2021 11; 3(11):1484-1499.
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Anti-latent TGF? binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy. Sci Transl Med. 2021 Sep 08; 13(610):eabf0376.
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Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion. Sci Adv. 2021 06; 7(24).
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Inhibition of the sonic hedgehog pathway activates TGF-?-activated kinase (TAK1) to induce autophagy and suppress apoptosis in thyroid tumor cells. Cell Death Dis. 2021 05 08; 12(5):459.
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Suppression of Rheumatoid Arthritis by Enhanced Lymph Node Trafficking of Engineered Interleukin-10 in Murine Models. Arthritis Rheumatol. 2021 05; 73(5):769-778.
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IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection. Commun Biol. 2021 03 05; 4(1):290.