Phosphatidylethanolamine Binding Protein
"Phosphatidylethanolamine Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously found basic protein that binds to phosphatidylethanolamine and NUCLEOTIDES. It is an endogenous inhibitor of RAF KINASES and may play a role in regulating SIGNAL TRANSDUCTION. Phosphatidylethanolamine-binding protein is the precursor of hippocampal cholinergic neurostimulating peptide, which is cleaved from the N-terminal region of the protein.
Descriptor ID |
D049488
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MeSH Number(s) |
D12.644.360.562 D12.776.157.661 D12.776.476.555
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Concept/Terms |
Phosphatidylethanolamine Binding Protein- Phosphatidylethanolamine Binding Protein
- Hippocampal Cholinergic Neurostimulating Peptide Precursor
- HCNP Precursor Protein
- Raf Kinase Inhibitor Protein
- Phosphatidylethanolamine-Binding Protein
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylethanolamine Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylethanolamine Binding Protein".
This graph shows the total number of publications written about "Phosphatidylethanolamine Binding Protein" by people in this website by year, and whether "Phosphatidylethanolamine Binding Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2006 | 1 | 1 | 2 |
2008 | 3 | 0 | 3 |
2009 | 2 | 0 | 2 |
2010 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2012 | 1 | 1 | 2 |
2013 | 3 | 1 | 4 |
2014 | 3 | 0 | 3 |
2015 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2017 | 1 | 1 | 2 |
2021 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphatidylethanolamine Binding Protein" by people in Profiles.
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Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop. Proc Natl Acad Sci U S A. 2022 06 21; 119(25):e2121867119.
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Limited inhibition of multiple nodes in a driver network blocks metastasis. Elife. 2021 05 11; 10.
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Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):13453-13458.
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Raf kinase inhibitor protein: lessons of a better way for ß-adrenergic receptor activation in the heart. J Physiol. 2017 06 15; 595(12):4073-4087.
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Gene expression in local stroma reflects breast tumor states and predicts patient outcome. Sci Rep. 2016 12 16; 6:39240.
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Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages. Cancer Res. 2015 Oct 01; 75(19):4063-73.
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Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):E364-73.
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Raf kinase inhibitory protein (RKIP) as a metastasis suppressor: regulation of signaling networks in cancer. Crit Rev Oncog. 2014; 19(6):447-54.
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RKIP structure drives its function: a three-state model for regulation of RKIP. Crit Rev Oncog. 2014; 19(6):483-8.
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A prognostic gene signature for metastasis-free survival of triple negative breast cancer patients. PLoS One. 2013; 8(12):e82125.