 Interferon Regulatory Factor-7
"Interferon Regulatory Factor-7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that is induced by INTERFERONS as well as LMP-1 protein from EPSTEIN-BARR VIRUS. IRF-7 undergoes PHOSPHORYLATION prior to nuclear translocation and it activates GENETIC TRANSCRIPTION of multiple interferon GENES.
| Descriptor ID |
D050839
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| MeSH Number(s) |
D12.644.360.024.302.437 D12.776.157.057.050.437 D12.776.260.504.437 D12.776.476.024.385.437 D12.776.744.631 D12.776.930.332.437
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| Concept/Terms |
IRF-7C Transcription Factor- IRF-7C Transcription Factor
- Factor, IRF-7C Transcription
- IRF 7C Transcription Factor
- Transcription Factor, IRF-7C
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Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-7".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-7".
This graph shows the total number of publications written about "Interferon Regulatory Factor-7" by people in this website by year, and whether "Interferon Regulatory Factor-7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factor-7" by people in Profiles.
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Ohguchi A, Yamauchi H, Doi K, Nakayama H. Activation of type I interferon signaling in the parotid and exorbital lachrymal glands during the acute phase of encephalomyocarditis (EMC) virus infection in mice. Exp Mol Pathol. 2016 06; 100(3):434-40.
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Mitra S, Wade MS, Sun X, Moldobaeva N, Flores C, Ma SF, Zhang W, Garcia JG, Jacobson JR. GADD45a promoter regulation by a functional genetic variant associated with acute lung injury. PLoS One. 2014; 9(6):e100169.
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Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, Hafler DA, Kellis M, Raychaudhuri S, Zhang F, Stranger BE, Benoist CO, De Jager PL, Regev A, Hacohen N. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science. 2014 Mar 07; 343(6175):1246980.
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O'Connor MA, Green WR. Use of IRF-3 and/or IRF-7 knockout mice to study viral pathogenesis: lessons from a murine retrovirus-induced AIDS model. J Virol. 2014 Feb; 88(4):2349-53.
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Otero DC, Baker DP, David M. IRF7-dependent IFN-ß production in response to RANKL promotes medullary thymic epithelial cell development. J Immunol. 2013 Apr 01; 190(7):3289-98.
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Salloum R, Franek BS, Kariuki SN, Rhee L, Mikolaitis RA, Jolly M, Utset TO, Niewold TB. Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients. Arthritis Rheum. 2010 Feb; 62(2):553-61.
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Joo CH, Shin YC, Gack M, Wu L, Levy D, Jung JU. Inhibition of interferon regulatory factor 7 (IRF7)-mediated interferon signal transduction by the Kaposi's sarcoma-associated herpesvirus viral IRF homolog vIRF3. J Virol. 2007 Aug; 81(15):8282-92.
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