Crk-Associated Substrate Protein
"Crk-Associated Substrate Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It is a signal transducing adaptor protein that undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.
| Descriptor ID |
D050719
|
| MeSH Number(s) |
D12.644.360.024.282 D12.776.157.057.016 D12.776.476.024.316 D12.776.744.425
|
| Concept/Terms |
Crk-Associated Substrate Protein- Crk-Associated Substrate Protein
- Crk Associated Substrate Protein
- Substrate Protein, Crk-Associated
- p130 Cas Protein
- Cas Protein, p130
- BCAR1 Protein
- p130 Crk-Associated Substrate
- Crk-Associated Substrate, p130
- Substrate, p130 Crk-Associated
- p130 Crk Associated Substrate
- p130Cas Protein
- Breast Cancer Anti-Estrogen Resistance 1 Protein
- Breast Cancer Anti Estrogen Resistance 1 Protein
- Crk-Associated Substrate
- Crk Associated Substrate
- CKRAS Protein
|
Below are MeSH descriptors whose meaning is more general than "Crk-Associated Substrate Protein".
Below are MeSH descriptors whose meaning is more specific than "Crk-Associated Substrate Protein".
This graph shows the total number of publications written about "Crk-Associated Substrate Protein" by people in this website by year, and whether "Crk-Associated Substrate Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Crk-Associated Substrate Protein" by people in Profiles.
-
Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells. J Biol Chem. 1997 Feb 14; 272(7):4230-6.
-
p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene. J Biol Chem. 1996 Oct 11; 271(41):25198-203.