 Chymases
"Chymases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
| Descriptor ID |
D053818
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| MeSH Number(s) |
D08.811.277.656.300.760.103 D08.811.277.656.959.350.103
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| Concept/Terms |
Chymases- Chymases
- Chymase
- Chymotrypsin-Like Proteases
- Chymotrypsin Like Proteases
- Chymotrypsin-Like Protease
- Chymotrypsin Like Protease
- Chymase-1
- Chymase 1
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Below are MeSH descriptors whose meaning is more general than "Chymases".
Below are MeSH descriptors whose meaning is more specific than "Chymases".
This graph shows the total number of publications written about "Chymases" by people in this website by year, and whether "Chymases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1996 | 0 | 2 | 2 | | 1998 | 0 | 2 | 2 | | 2000 | 0 | 2 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chymases" by people in Profiles.
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Saadalla AM, Osman A, Gurish MF, Dennis KL, Blatner NR, Pezeshki A, McNagny KM, Cheroutre H, Gounari F, Khazaie K. Mast cells promote small bowel cancer in a tumor stage-specific and cytokine-dependent manner. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):1588-1592.
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Seo GY, Lee JM, Jang YS, Kang SG, Yoon SI, Ko HJ, Lee GS, Park SR, Nagler CR, Kim PH. Mechanism underlying the suppressor activity of retinoic acid on IL4-induced IgE synthesis and its physiological implication. Cell Immunol. 2017 Dec; 322:49-55.
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Choi HW, Bowen SE, Miao Y, Chan CY, Miao EA, Abrink M, Moeser AJ, Abraham SN. Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules. Immunity. 2016 12 20; 45(6):1258-1269.
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Lynch JP, Renz CL, Laroche D, Moss J. Value of baseline levels in assessing tryptase release. Inflamm Res. 2000 Apr; 49 Suppl 1:S23-4.
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Kim JS, Kubota H, Nam SY, Doi K, Saegusa J. Expression of cytokines and proteases in mast cells in the lesion of subcapsular cell hyperplasia in mouse adrenal glands. Toxicol Pathol. 2000 Mar-Apr; 28(2):297-303.
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Kanthawatana S, Carias K, Arnaout R, Hu J, Irani AM, Schwartz LB. The potential clinical utility of serum alpha-protryptase levels. J Allergy Clin Immunol. 1999 Jun; 103(6):1092-9.
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Renz CL, Laroche D, Thurn JD, Finn HA, Lynch JP, Thisted R, Moss J. Tryptase levels are not increased during vancomycin-induced anaphylactoid reactions. Anesthesiology. 1998 Sep; 89(3):620-5.
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Jackson DS, Fraser SA, Ni LM, Kam CM, Winkler U, Johnson DA, Froelich CJ, Hudig D, Powers JC. Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase. J Med Chem. 1998 Jun 18; 41(13):2289-301.
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Ibrahim MZ, Reder AT, Lawand R, Takash W, Sallouh-Khatib S. The mast cells of the multiple sclerosis brain. J Neuroimmunol. 1996 Nov; 70(2):131-8.
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Naclerio RM, Hubbard W, Lichtenstein LM, Kagey-Sobotka A, Proud D. Origin of late phase histamine release. J Allergy Clin Immunol. 1996 Oct; 98(4):721-3.
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