"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Descriptor ID |
D012333
|
MeSH Number(s) |
D13.444.735.544
|
Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 12 | 36 | 48 |
1995 | 3 | 47 | 50 |
1996 | 10 | 35 | 45 |
1997 | 10 | 52 | 62 |
1998 | 4 | 30 | 34 |
1999 | 3 | 37 | 40 |
2000 | 7 | 41 | 48 |
2001 | 5 | 57 | 62 |
2002 | 4 | 57 | 61 |
2003 | 5 | 64 | 69 |
2004 | 5 | 74 | 79 |
2005 | 5 | 46 | 51 |
2006 | 2 | 46 | 48 |
2007 | 8 | 47 | 55 |
2008 | 8 | 62 | 70 |
2009 | 5 | 41 | 46 |
2010 | 7 | 50 | 57 |
2011 | 3 | 43 | 46 |
2012 | 10 | 41 | 51 |
2013 | 11 | 34 | 45 |
2014 | 10 | 32 | 42 |
2015 | 18 | 41 | 59 |
2016 | 11 | 19 | 30 |
2017 | 9 | 28 | 37 |
2018 | 9 | 19 | 28 |
2019 | 15 | 13 | 28 |
2020 | 3 | 17 | 20 |
2021 | 5 | 17 | 22 |
2022 | 4 | 20 | 24 |
2023 | 1 | 18 | 19 |
2024 | 5 | 11 | 16 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency. Sci Adv. 2024 Oct 18; 10(42):eadp7727.
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Microbiome-induced reprogramming in post-transcriptional landscape using nanopore direct RNA sequencing. Cell Rep. 2024 Oct 22; 43(10):114798.
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Rogaratinib Plus Atezolizumab in Cisplatin-Ineligible Patients With FGFR RNA-Overexpressing Urothelial Cancer: The FORT-2 Phase 1b Nonrandomized Clinical Trial. JAMA Oncol. 2024 Nov; 10(11):1565-1570.
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Global impact of unproductive splicing on human gene expression. Nat Genet. 2024 Sep; 56(9):1851-1861.
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IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 Aug 28; 15(1):7421.
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RNA interacts with topoisomerase I to adjust DNA topology. Mol Cell. 2024 Sep 05; 84(17):3192-3208.e11.
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Proximity sequencing for the detection of mRNA, extracellular proteins and extracellular protein complexes in single cells. Nat Protoc. 2024 Dec; 19(12):3568-3589.
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Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display. J Am Chem Soc. 2024 Aug 28; 146(34):24053-24060.
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Pseudouridine Detection and Quantification Using Bisulfite Incorporation Hindered Ligation. ACS Chem Biol. 2024 Aug 16; 19(8):1813-1819.
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Internal mRNA 2'-O-methyl mapping by nanopore sequencing and consequence on mRNA stability and role in cancer. Mol Cell. 2024 Jun 20; 84(12):2215-2217.