"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
| Descriptor ID |
D012333
|
| MeSH Number(s) |
D13.444.735.544
|
| Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 10 | 35 | 45 |
| 1997 | 9 | 52 | 61 |
| 1998 | 4 | 30 | 34 |
| 1999 | 3 | 37 | 40 |
| 2000 | 7 | 41 | 48 |
| 2001 | 5 | 57 | 62 |
| 2002 | 4 | 58 | 62 |
| 2003 | 5 | 63 | 68 |
| 2004 | 6 | 74 | 80 |
| 2005 | 5 | 46 | 51 |
| 2006 | 2 | 47 | 49 |
| 2007 | 8 | 48 | 56 |
| 2008 | 8 | 62 | 70 |
| 2009 | 5 | 44 | 49 |
| 2010 | 7 | 50 | 57 |
| 2011 | 3 | 43 | 46 |
| 2012 | 11 | 42 | 53 |
| 2013 | 11 | 34 | 45 |
| 2014 | 10 | 34 | 44 |
| 2015 | 19 | 43 | 62 |
| 2016 | 13 | 19 | 32 |
| 2017 | 10 | 33 | 43 |
| 2018 | 11 | 21 | 32 |
| 2019 | 17 | 14 | 31 |
| 2020 | 5 | 23 | 28 |
| 2021 | 5 | 20 | 25 |
| 2022 | 5 | 24 | 29 |
| 2023 | 1 | 24 | 25 |
| 2024 | 10 | 14 | 24 |
| 2025 | 4 | 6 | 10 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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m6A mRNA methylation decorates genes involved in fibrinogen synthesis to regulate liver regeneration in mice. Am J Physiol Gastrointest Liver Physiol. 2025 Nov 01; 329(5):G614-G627.
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FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia. Sci Adv. 2025 Aug 15; 11(33):eadv7648.
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Development of Emerin mRNA Lipid Nanoparticles to Rescue Myogenic Differentiation. Int J Mol Sci. 2025 Aug 12; 26(16).
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RNA binding proteins PCBP1 and PCBP2 regulate pancreatic ß cell translation. Mol Metab. 2025 Aug; 98:102175.
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Endotoxin-induced m6A RNA methylation landscape in lung endothelial cells: role of METTL3 in regulating inflammation and injury during acute lung injury. Biochim Biophys Acta Mol Basis Dis. 2025 08; 1871(6):167907.
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N6-methyladenosine reader YTHDF2 in cell state transition and antitumor immunity. RNA. 2025 Feb 19; 31(3):395-401.
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Distinct plasmablast developmental intermediates produce graded expression of IgM secretory transcripts. Cell Rep. 2025 Feb 25; 44(2):115283.
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Characterization and molecular targeting of CFIm25 (NUDT21/CPSF5) mRNA using miRNAs. FASEB J. 2025 Jan 31; 39(2):e70324.
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Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism. Nat Commun. 2025 Jan 09; 16(1):533.
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Quantitative RNA pseudouridine maps reveal multilayered translation control through plant rRNA, tRNA and mRNA pseudouridylation. Nat Plants. 2025 02; 11(2):234-247.