"Cullin Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of structurally related proteins that were originally discovered for their role in cell-cycle regulation in CAENORHABDITIS ELEGANS. They play important roles in regulation of the CELL CYCLE and as components of UBIQUITIN-PROTEIN LIGASES.
| Descriptor ID |
D044842
|
| MeSH Number(s) |
D08.811.464.938.750.750.500 D12.776.167.175
|
| Concept/Terms |
Cullin Proteins- Cullin Proteins
- Cullin Domain Proteins
- Cullins
- Cullin Domain Protein
- Cullin Protein
|
Below are MeSH descriptors whose meaning is more general than "Cullin Proteins".
Below are MeSH descriptors whose meaning is more specific than "Cullin Proteins".
This graph shows the total number of publications written about "Cullin Proteins" by people in this website by year, and whether "Cullin Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cullin Proteins" by people in Profiles.
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Scaled and efficient derivation of loss-of-function alleles in risk genes for neurodevelopmental and psychiatric disorders in human iPSCs. Stem Cell Reports. 2024 Oct 08; 19(10):1489-1504.
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CAND1 orchestrates CRLs through rock and roll. Cell. 2023 04 27; 186(9):1817-1818.
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YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. PLoS Biol. 2020 04; 18(4):e3000664.
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Novel KLHL26 variant associated with a familial case of Ebstein's anomaly and left ventricular noncompaction. Mol Genet Genomic Med. 2020 04; 8(4):e1152.
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A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation. J Exp Med. 2014 Jun 02; 211(6):1137-51.
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Inhibition of CUL4A Neddylation causes a reversible block to SAMHD1-mediated restriction of HIV-1. J Virol. 2013 Nov; 87(21):11741-50.
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BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Nature. 2012 Nov 22; 491(7425):618-21.
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KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Mol Cell. 2009 Oct 09; 36(1):131-40.
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Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell. 2009 Oct 09; 36(1):39-50.
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Intermittent hypoxia regulates RNA polymerase II in hippocampus and prefrontal cortex. Neuroscience. 2009 Feb 18; 158(4):1436-45.